No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lactase Enzyme Ingredients & Drug Interactions

by Puritan's Pride

Softgel Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lactase Enzyme is a dietary supplement by Puritan's Pride with 1 active ingredient. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lactase Enzyme by Puritan's Pride

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Puritan's Pride Lactase Enzyme contains one active ingredient: lactase enzyme, an enzyme that breaks down lactose (the sugar in milk and dairy products) so your body can digest it more easily. The inactive ingredients are soybean oil, maltodextrin, gelatin, glycerin, soy lecithin, turmeric extract, and yellow beeswax — these are fillers, binders, and capsule materials that hold the enzyme stable.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: milk and dairy digestant; supports digestive health.
  • We looked for evidence on: Lactose intolerance, lactose malabsorption, dairy digestion, milk sensitivity.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase enzyme is rated effective for lactose intolerance — the condition where your body has trouble digesting dairy because it doesn't make enough of this enzyme naturally. For prematurity and colic, the evidence isn't established enough to rate it either way.

If you're taking this to manage lactose intolerance, the data supports its use.

The evidence, ingredient by ingredient Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase enzyme is generally well tolerated when used as directed. A rare case of contact dermatitis and allergic rhinoconjunctivitis (itchy, inflamed nose and eyes) has been reported in a worker exposed to powdered lactase — an occupational exposure scenario — so if you've ever had an allergic reaction to lactase itself, steer clear.

For pregnancy and breastfeeding, the safety data rates it likely safe, though the notes advise checking with your doctor before regular use during pregnancy and asking your doctor or pharmacist first if you're nursing, since the data is limited.

Side effects, ingredient by ingredient Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the lactase enzyme in this product. That said, confirm it with your own doctor or pharmacist before starting, especially if you take medications regularly.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Lactase Enzyme by Puritan's Pride is straightforward for lactose intolerance. If you're pregnant, nursing, or take medications regularly, a quick conversation with your doctor or pharmacist before you start is a good idea.

Anyone with a known allergy to lactase should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactase Enzyme, straight from the product label.

Brand Puritan's Pride
Barcode (UPC) 074312149320
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318157
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactase Enzyme by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
Servings per container
40
UPC/BARCODE
074312149320
IngredientAmount% DV
Lactase Enzyme375 mg--

Other ingredients: Soybean Oil, Maltodextrin, Gelatin, Glycerin, Soy Lecithin, Turmeric Extract, Yellow Beeswax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Puritan's Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health... choose the best.

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Do not use if seal under cap is broken or missing.

Keep out of reach of children.

Contains wheat and soy ingredients.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Puritan's Pride is a registered trademark

Formulation

Milk & dairy digestant Supports digestive health Different color Same product

Contains ingredients that may result in a variation of color and appearance over time.

No artificial flavor or sweetener, no sugar, no milk, no lactose, no fish. Sodium free.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take three (3) softgels just before consuming food or drink that contains lactose. Take one (1) softgel with medications or supplements that contain lactose. These softgels should be swallowed, and should not be added directly to milk or other dairy products.

See for yourself

Lactase Enzyme by Puritan's Pride label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lactase Enzyme by Puritan's Pride

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container40 Amounts shown are per serving.

Lactase Enzyme

No known
interactions
375 mg per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase Enzyme monograph & interactions

Other (inactive) ingredients: Soybean Oil, Maltodextrin, Gelatin, Glycerin, Soy Lecithin, Turmeric Extract, Yellow Beeswax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactase Enzyme by Puritan's Pride Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lactase Enzyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lactase Enzyme, from the product label.

Puritan's Pride

See all Puritan's Pride products
Name
Puritan's Pride, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
1-800-645-1030
Web Address
www.puritan.com
Pharmacist Counseling Corner

Lactase Enzyme by Puritan's Pride: Common Questions

Does Lactase Enzyme by Puritan's Pride interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lactase Enzyme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lactase Enzyme contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lactase enzyme actually help with lactose intolerance?
Yes — it's rated effective for lactose intolerance. The enzyme breaks down lactose in your digestive tract so your body can absorb it, which is exactly what happens naturally when your own lactase production is low or absent.
Can I take this if I'm pregnant or breastfeeding?
The safety data rates lactase enzyme likely safe in pregnancy and breastfeeding. That said, the notes advise you to check with your doctor before regular use during pregnancy and to ask your doctor or pharmacist first if you're nursing, since the data is limited. A quick conversation with them will help you decide what's right for your situation.
Are there any side effects I should know about?
Lactase enzyme is generally well tolerated. A rare case of allergic reaction (contact dermatitis and allergic rhinoconjunctivitis) has been reported, but it occurred in a worker exposed to powdered lactase in an occupational setting. If you've ever had an allergic reaction to lactase, avoid this product.
What are the inactive ingredients?
The capsule and formula contain soybean oil, maltodextrin, gelatin, glycerin, soy lecithin, turmeric extract, and yellow beeswax. If you're allergic to soy or bee products, let your doctor or pharmacist know before taking it.
Will this help with colic or prematurity?
For both colic and prematurity, there isn't enough evidence to say whether it helps or doesn't. Lactase enzyme is proven effective for lactose intolerance, but the data on those other uses is too limited to rate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactase Enzyme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactase Enzyme label
Go deeper

The Full Monographs Behind Lactase Enzyme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lactase Enzyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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