Less Stress, More Yes Mango Lemon Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Less Stress, More Yes Mango Lemon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Less Stress, More Yes Mango Lemon is a dietary supplement by N by Nutrilite with 2 active ingredients. Its ingredients are commonly taken for anxiety and stress, relaxation and calm, sleep support.Based on those ingredients, 581 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Theanine, Lemon Balm (aerial) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Less Stress, More Yes Mango Lemon by N by Nutrilite
Ask about any prescription or over-the-counter medication and we check it for interactions with Less Stress, More Yes Mango Lemon by N by Nutrilite — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Less Stress, More Yes Mango Lemon by N by Nutrilite
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has 2 active ingredients. L-theanine is an amino acid that may support calm focus and cognitive function.
Lemon balm aerial extract is a plant-based ingredient traditionally used for stress and mood support. The remaining ingredients — tapioca syrup, cane sugar, water, glycerin, agar, citric acid, lactic acid, natural flavors, turmeric, locust bean gum, and paprika — are inactive ingredients that give the gummy its texture, taste, and shelf stability.
Does it work?
Moderate evidence
L-theanine is possibly effective for supporting cognitive function, though the evidence for age-related cognitive decline and Alzheimer's disease is insufficient to rate. Its effectiveness for anxiety disorders, OCD, or cancer is also not well established in the data we hold.
Lemon balm extract is possibly effective for cold sores and stress, and possibly effective for mood support. The evidence for depression is listed as possibly effective as well.
How safe is it?
Well-documented data
L-theanine is generally well tolerated for short-term use in healthy adults, but long-term safety hasn't been well studied. The most common side effects are headaches, drowsiness, and increased dream activity.
One case of facial tics was reported in a child, though it wasn't clearly linked to the ingredient. Lemon balm is generally well tolerated for short-term use, and studies show it doesn't impair reaction time or cognitive performance even when combined with alcohol.
One case of heart rhythm changes was reported with a multi-ingredient product containing lemon balm, but it's unclear if lemon balm was the cause. There's not enough safety data for either ingredient during pregnancy; the facts advise against use unless your doctor advises otherwise.
For breastfeeding, lemon balm safety information is limited — talk with your doctor or pharmacist before use.
Meds to double-check
Moderate interaction found
Before you take this, double-check with your doctor or pharmacist if you're on thyroid hormone replacement therapy (lemon balm may interfere with it) or blood pressure medications (L-theanine may lower pressure further). Also flag any CNS depressants — sedatives, sleep aids, anxiety medications, or pain relievers that make you drowsy — since both ingredients can add to that effect.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood pressure medications, thyroid hormone replacement, or sedating medications (sleep aids, anxiety drugs, pain relievers), talk with your doctor or pharmacist before starting this product. L-theanine and lemon balm are generally well tolerated short-term, but long-term safety data is limited.
Avoid during pregnancy unless your doctor says it's okay, and check with your pharmacist if you're breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Less Stress, More Yes Mango Lemon, straight from the product label.
| Brand | N by Nutrilite |
|---|---|
| Barcode (UPC) | 850210008460 |
| Net contents | 60 Gummy(ies) |
| Market status | On market |
| Date entered into DSLD | Apr 22, 2021 |
| DSLD ID | 246527 |
| Product type | Other Combinations |
| Supplement form | Gummy Or Jelly |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Less Stress, More Yes Mango Lemon by N by Nutrilite, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Total Carbohydrates | 5 Gram(s) | 2% |
| L-Theanine | 50 mg | -- |
| Added Sugars | 3 Gram(s) | 6% |
| Total Sugars | 3 Gram(s) | -- |
| Lemon Balm (aerial) extract | 20 mg | -- |
Other ingredients: Tapioca Syrup, Cane Sugar, Water, Glycerin, Agar, Citric Acid, Lactic Acid, Natural Flavors, Turmeric, Locust Bean Gum, Paprika
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Feeling stressed? Try these great tasting gummies!
U got this.
Exclusively from Amway
Formulation
Free from all the nasties of artificial flavors, sweeteners, and colors.
These can help you find you Zen.
Free From: Peanuts, tree nuts, soy, eggs, high fructose corn syrup, shellfish, and crustacean. GF (Gluten free) Dairy free
V (Vegetarian)
Produced following Amway standards.
Relax
Product of Colombia.
Formula
The Good Stuff L-Theanine - a natural amino acid known to help reduce occasional stress. Lemon Balm - used traditionally as a calming botanical.
Mango lemon with other natural flavors
L-Theanine & lemon balm
Precautions
Keep out of the reach of children
If you have a medical condition, long-term stress disorder, chronic illness, are taking prescription drugs or are pregnant or nursing, please consult your healthcare professional prior to use.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Use Instructions: Adults: Take 2 gummies daily. Chew thoroughly before swallowing.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Less Stress, More Yes Mango Lemon by N by Nutrilite label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Less Stress, More Yes Mango Lemon by N by Nutrilite
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Theanine
Interacts with565 drugs
Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...
L-Theanine monograph & interactionsLemon Balm (aerial) extract
Interacts with264 drugs
Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold so...
Lemon Balm (aerial) extract monograph & interactionsOther (inactive) ingredients: Tapioca Syrup, Cane Sugar, Water, Glycerin, Agar, Citric Acid, Lactic Acid, Natural Flavors, Turmeric, Locust Bean Gum, Paprika. These complete the product’s ingredient list but are not active constituents.
Less Stress, More Yes Mango Lemon by N by Nutrilite Drug Interactions
HelloPharmacist Interaction Report
Less Stress, More Yes Mango Lemon by N by Nutrilite contains L-theanine and lemon balm extract, both of which have documented interactions with medications.
The most serious concern is a moderate-severity interaction: lemon balm may interfere with thyroid hormone replacement therapy by blocking the signal that tells your thyroid how much hormone to make.
Read the full breakdown — every affected drug type, severity by severity
L-theanine can lower blood pressure (moderate severity), which means it may strengthen the effects of blood pressure medications — your pressure could drop lower than intended. Both ingredients also carry minor or moderate concerns with CNS depressants (sedatives, sleep aids, anxiety medications, pain relievers with sedating effects): lemon balm's effect is moderate, while theanine's is minor, and together they could add up to extra drowsiness or sedation.
Theanine also has a minor theoretical interaction with serotonergic drugs (antidepressants that work on serotonin), though no cases of serotonin syndrome have been reported with it.
Altogether, these interactions span 581 individual medications. Use the search tool below to check your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Less Stress, More Yes Mango Lemon?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Less Stress, More Yes Mango Lemon interact with 581 drugs. Click any drug to see the details.
2 of the 2 ingredients in Less Stress, More Yes Mango Lemon interact with drugs. Each result below shows which ingredient is responsible. L-Theanine Lemon Balm (aerial) extract
AmbrisentanLetairis, Volibris
How Ambrisentan interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amiloride, Hydrochlorothiazide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aminoglutethimide interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aminophylline, Amobarbital, Ephedrine interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aminophylline, Amobarbital, Ephedrine interactionAmitriptylineElavil
How Amitriptyline interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Amitriptyline interactionL-theanineSerotonergic Drugs, Cns Depressants Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Amitriptyline, Chlordiazepoxide interactionL-theanineCns Depressants, Serotonergic Drugs Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Amitriptyline, Perphenazine interactionL-theanineSerotonergic Drugs, Cns Depressants Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Ammonium Chloride interactionAmobarbitalAmytal
How Amobarbital interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Amobarbital interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Amobarbital, Ephedrine Sulfate interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Amobarbital, Secobarbital interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Amobarbital, Secobarbital interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aprobarbital, Butabarbital, Phenobarbital interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aprobarbital, Butabarbital, Phenobarbital interactionAprocitentanTryvio
How Aprocitentan interacts with Less Stress, More Yes Mango Lemon — through 1 ingredient. Tap an ingredient for the detail:
L-theanineAntihypertensive Drugs Moderate
Interaction Summary
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full L-theanine + Aprocitentan interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aripiprazole interactionL-theanineCns Depressants, Serotonergic Drugs Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aripiprazole Lauroxil interactionL-theanineSerotonergic Drugs, Cns Depressants Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Aripiprazole Lauroxil interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Caffeine, Codeine Phosphate interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Caffeine, Hydrocodone interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Carisoprodol, Codeine Phosphate interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Codeine Phosphate interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Less Stress, More Yes Mango Lemon — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm (aerial) ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm (aerial) Extract + Aspirin, Codeine Phosphate, Methocarbamol interactionL-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Aspirin, Codeine Phosphate, Methocarbamol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Less Stress, More Yes Mango Lemon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Theanine
Antihypertensive Drugs
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.
Cns Depressants
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.
Serotonergic Drugs
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.
Lemon Balm (aerial) extract
Cns Depressants
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.
Thyroid Hormone
Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.
Brand information
Manufacturer and brand details for Less Stress, More Yes Mango Lemon, from the product label.
N by Nutrilite
See all N by Nutrilite products- Name
- Amway Corp.
- City
- Ada
- State
- MI
- ZipCode
- 49355
- Phone Number
- 1-800-253-6500
- Web Address
- Amway.com
Less Stress, More Yes Mango Lemon by N by Nutrilite: Common Questions
Does Less Stress, More Yes Mango Lemon by N by Nutrilite interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects?
Does L-theanine actually help with focus and thinking?
Can lemon balm really help with stress and mood?
Will this make me drowsy?
Is this safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Less Stress, More Yes Mango Lemon’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Theanine
Interacts with 565 drugsTheanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong drowsiness. Early research suggests it may...
Read the full Theanine monograph → Herb & supplement monographLemon Balm
Interacts with 264 drugsLemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...
Read the full Lemon Balm monograph →Sources & How We Checked
Less Stress, More Yes Mango Lemon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Theanine 6 references
- Yokogoshi H, Kobayashi M. Hypotensive effect of gamma-glutamylethylamide in spontaneously hypertensive rats. Life Sci 1998;62:1065-8.
- Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., and Scholey, A. B. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol.Psychol. 2008;77(2):113-122. PubMed
- Yokogoshi, H., Kato, Y., Sagesaka, Y. M., Takihara-Matsuura, T., Kakuda, T., and Takeuchi, N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci.Biotechnol.Biochem. 1995;59(4):615-618. PubMed
- Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011;16(4):348-
- Hidese S, Ota M, Wakabayashi C, et al. Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Acta Neuropsychiatr 2017;29(2):72-9.
- Tsuchiya T, Honda H, Oikawa M, et al. Oral administration of the amino acids cystine and theanine attenuates the adverse events of S-1 adjuvant chemotherapy in gastrointestinal cancer patients. Int J Clin Oncol 2016;21(6):1085-90. PubMed
Lemon Balm 12 references
- Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
- Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
- Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
- Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
- Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
- Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
- Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
- Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
- Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
- Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
- Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
- Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC