Lion's Mane Berry Flavor Ingredients & Drug Interactions
by Horbaach
What is this page for?
First and foremost: checking Lion's Mane Berry Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lion's Mane Berry Flavor is a dietary supplement by Horbaach with 2 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 511 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane Mushroom Fruiting Body Extract, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Lion's Mane Berry Flavor by Horbaach
Ask about any prescription or over-the-counter medication and we check it for interactions with Lion's Mane Berry Flavor by Horbaach — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Lion's Mane Berry Flavor by Horbaach
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients. Sodium is an electrolyte your body needs in small amounts to manage fluid balance and nerve function, but the amount in this gummy is a dosing consideration if you're watching your sodium intake or taking blood pressure or heart medications.
Lion's Mane Mushroom Fruiting Body Extract is derived from the fruiting body of the lion's mane fungus. The product also contains inactive ingredients — sugar, glucose syrup, pectin, citric acid, fruit and vegetable juice, sodium citrate, natural flavors, and vitamin E — which serve as sweeteners, gelling agents, and preservatives.
Does it work?
Not established
The evidence on Lion's Mane Mushroom for cognitive function, anxiety, Alzheimer disease, and other uses we hold data on is insufficient to establish whether it works for those purposes. For Sodium, the data shows it is likely effective for cystic fibrosis and possibly effective for reducing kidney damage from the antifungal drug amphotericin B, but evidence is insufficient to establish use in heart failure or bipolar disorder.
Since this is a gummy with berry flavor, it's not being marketed for those clinical uses anyway.
How safe is it?
Well-documented data
Sodium is well tolerated in the amounts most people get from food — the safety caution is against excess intake without medical advice. Too much dietary sodium is linked to high blood pressure and strain on your heart and kidneys.
Lion's Mane Mushroom is generally well tolerated as a food; the most common side effects reported in studies are gastrointestinal discomfort, nausea, and occasionally skin rash. Long-term supplement safety hasn't been well studied, and the safety data advises against use during pregnancy and breastfeeding due to insufficient information.
Meds to double-check
Moderate interaction found
Talk to your pharmacist before taking this if you use blood pressure medications, lithium, corticosteroids, HIV medications like didanosine, blood thinners, diabetes medications, immunosuppressants, or any drug that contains sodium. These are the medication types with Moderate interactions documented for the ingredients in this product.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood pressure medications, lithium, immunosuppressants, diabetes drugs, or blood thinners, check with your pharmacist before using this gummy — sodium and lion's mane both have documented interactions. If you're watching your sodium intake for heart or kidney health, ask your pharmacist whether this product fits your diet.
Otherwise, for most people without those medications or conditions, the individual ingredients are generally well tolerated.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lion's Mane Berry Flavor, straight from the product label.
| Brand | Horbaach |
|---|---|
| Barcode (UPC) | X0042CE8HT |
| Net contents | 60 Vegan Gummy(ies) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 331657 |
| Product type | Botanical |
| Supplement form | Gummy Or Jelly |
| Dietary claims / uses | All Other |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lion's Mane Berry Flavor by Horbaach, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Total Carbohydrates | 5 Gram(s) | 2% |
| Sodium | 20 mg | 1% |
| Added Sugars | 4 Gram(s) | -- |
| Total Sugars | 4 Gram(s) | -- |
| Lion's Mane Mushroom Fruiting Body Extract | 750 mg | -- |
Other ingredients: Sugar, Glucose Syrup, Pectin, Citric Acid, Fruit and Vegetable Juice, Sodium Citrate, Natural Flavors, Vitamin E
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
New
Our mission is simple-to provide the best nutritional care you need to live happy and healthy, the Horbaach way.
Formulation
Horbaach Non-GMO Promise
At Horbaach, it's been our promise to deliver the highest quality vitamins and self care products for over 40 years. It starts with meticulously sourcing the best ingredients from around the globe, then manufacturing them to the highest standards, and finally testing them here in the USA to confirm we are best in class. We put all our products to the test in our cutting-edge laboratory to guarantee the utmost purity and potency.
Non-GMO / Gluten free
No gluten, wheat, yeast, milk, lactose, soy, artificial sweetener Non-GMO Vegan formula
Non-GMO Vegan formula
Precautions
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.
Keep out of reach of children.
Storage
Store in a cool, dry place. Avoid excessive heat.
Brand IP Statement(s)
Copyright 2024 Horbaach Manufacturing LLC
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take three (3) vegan gummies daily, preferably with a meal.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lion's Mane Berry Flavor by Horbaach label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lion's Mane Berry Flavor by Horbaach
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Vegan Gummy(ies) Dosage formGummy Or Jelly Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsLion's Mane Mushroom Fruiting Body Extract
Interacts with327 drugs
Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...
Lion's Mane Mushroom Fruiting Body Extract monograph & interactionsOther (inactive) ingredients: Sugar, Glucose Syrup, Pectin, Citric Acid, Fruit and Vegetable Juice, Sodium Citrate, Natural Flavors, Vitamin E. These complete the product’s ingredient list but are not active constituents.
Lion's Mane Berry Flavor by Horbaach Drug Interactions
HelloPharmacist Interaction Report
Horbaach's Lion's Mane Berry Flavor Gummy contains two active ingredients, and both carry documented interactions with medications.
Sodium is the primary concern here. It interacts with blood pressure medications (antihypertensives) at Moderate severity — high sodium intake can reduce how well these drugs work and may require you to take more of them to control your blood pressure.
Read the full breakdown — every affected drug type, severity by severity
Sodium also interacts Moderately with corticosteroids (steroids that retain sodium in your body), lithium (a mood stabilizer where sodium changes can cause toxicity), didanosine (an HIV medication), sodium phosphate bowel-prep solutions, tolvaptan (a drug that raises sodium levels), and other sodium-containing medications. The risk in all these cases centers on dangerously high blood sodium levels.
Lion's Mane Mushroom Fruiting Body Extract carries Moderate interactions with blood thinners (anticoagulants and antiplatelets) — it may increase bleeding risk — with diabetes medications where it could add to their blood-sugar-lowering effect, and with immunosuppressants used after transplant or for autoimmune conditions, where it might interfere with their job. Altogether, these interactions span 504 individual medications.
Check your exact medications using the tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Lion's Mane Berry Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Lion's Mane Berry Flavor interact with 511 drugs. Click any drug to see the details.
2 of the 2 ingredients in Lion's Mane Berry Flavor interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane Mushroom Fruiting Body Extract Sodium
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane Mushroom Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom Fruiting Body Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Lion's Mane Berry Flavor — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Lion's Mane Berry Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lion's Mane Mushroom Fruiting Body Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.
Immunosuppressants
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Lion's Mane Berry Flavor, from the product label.
Horbaach
See all Horbaach products- Name
- Horbaach Manufacturing LLC
- City
- Las Vegas
- State
- NV
- ZipCode
- 89703
- Phone Number
- 1-800-945-8802
Lion's Mane Berry Flavor by Horbaach: Common Questions
Does Lion's Mane Berry Flavor by Horbaach interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the main side effects of lion's mane mushroom?
Is the sodium content a problem if I'm on a low-sodium diet?
Does lion's mane mushroom actually help with memory or brain function?
Can I take this with my diabetes medication?
What are the inactive ingredients, and are there any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lion's Mane Berry Flavor is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lion's Mane Berry Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographLion's Mane Mushroom
Interacts with 327 drugsLion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...
Read the full Lion's Mane Mushroom monograph →Sources & How We Checked
Lion's Mane Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 44 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
- Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
- Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
- Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
- Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
- Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
- D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
- Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
- Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
- Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
- Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
- Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
- Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
- Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
- O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
- Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
- Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
- Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
- He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
- Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
- Messerli FH, Hofstetter L, Syrogiannouli L, et al. Sodium intake, life expectancy, and all-cause mortality. Eur Heart J 2021;42(21):2103-2112. PubMed
- Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev 2020;12(12):CD004022. PubMed
- Giatti S, Santos RB, Aielo AN, et al. Association of sodium with obstructive sleep apnea. The ELSA-Brasil study. Ann Am Thorac Soc 2021;18(3):502-510. PubMed
- Nan X, Lu H, Wu J, et al. The interactive association between sodium intake, alcohol consumption and hypertension among elderly in northern China: a cross-sectional study. BMC Geriatr 2021;21(1):135. PubMed
- Kyozuka H, Fukusda T, Murata T, et al. Impact of preconception sodium intake on hypertensive disorders of pregnancy: The Japan Environment and Children's study. Pregnancy Hypertens 2021;23:66-72. PubMed
- Zhao L, Ogden CL, Yang Q, et al. Association of usual sodium intake with obesity among US children and adolescents, NHANES 2009-2016. Obesity (Silver Spring) 2021;29(3):587-594. PubMed
- Ma Y, He FJ, Sun Q, et al. 24-Hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med 2022;386(3):252-263. PubMed
- Liu J, Yang X, Zhang P, et al. Association of urinary sodium excretion and left ventricular hypertrophy in people with type 2 diabetes mellitus: A cross-sectional study. Front Endocrinol (Lausanne) 2021;12:728493. PubMed
- Filippini T, Malavolti M, Whelton PK, Vinceti M. Sodium intake and risk of hypertension: A systematic review and dose-response meta-analysis of observational cohort studies. Curr Hypertens Rep 2022;24(5):133-144. PubMed
- Wang DD, Li Y, Nguyen XT, et al. Dietary sodium and potassium intake and risk of non-fatal cardiovascular diseases: The million veteran program. Nutrients 2022;14(5):1121. PubMed
- Kwak JH, Park CH, Eun CS, et al. The associations of dietary intake of high sodium and low zinc with gastric cancer mortality: A prospective cohort study in Korea. Nutr Cancer 2022;74(10):3501-3508. PubMed
- George S, Maiti R, Mishra BR, Jena M, Mohapatra D. Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial. Bipolar Disord 2023;25(1):66-75. PubMed
- Zhou TL, Schütten MTJ, Kroon AA, et al. Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. J Am Heart Assoc 2023;12(1):e026578. PubMed
Lion's Mane Mushroom 6 references
- Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
- Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
- Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
- Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
- Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
- Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.
See these in context on the Lion's Mane Mushroom monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC