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Dietary supplement

Lion's Mane Gummies Blueberry Flavored Ingredients & Drug Interactions

by Host Defense Mushrooms

Lion's Mane Gummies Blueberry Flavored label
See full label image
Gummy Or Jelly Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lion's Mane Gummies Blueberry Flavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lion's Mane Gummies Blueberry Flavored is a dietary supplement by Host Defense Mushrooms with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms

Ask about any prescription or over-the-counter medication and we check it for interactions with Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lion's mane mushroom, a fungus traditionally used in Asian medicine and now studied for potential effects on brain function. The gummies also include inactive ingredients like tapioca syrup, cane sugar, and agar for texture, plus natural flavoring and citric acid.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lion's Mane Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support for cognition, memory, and focus.
  • We looked for evidence on: Cognitive function, Memory, Cognitive impairment, Dementia, Alzheimer disease, Parkinson disease — and 4 related terms.
  • The closest evidence on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Cognitive function, Cognitive impairment, Dementia, and more.

The evidence for lion's mane isn't established yet. The facts we hold show insufficient reliable evidence to rate it for Alzheimer disease, anxiety, athletic performance, cancer, cognitive function, or cognitive impairment.

That doesn't mean it doesn't work—it means we don't have enough solid human research to say one way or the other. If you're considering it for a specific reason, your pharmacist can discuss what preliminary research exists and whether it makes sense for your situation.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lion's mane is generally well tolerated as a food, but its safety as a long-term supplement hasn't been studied extensively. The most common side effects are gastrointestinal discomfort, nausea, and skin rash—usually mild and infrequent.

The safety data available advises against use during pregnancy and breastfeeding, so talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking if you use blood thinners or antiplatelet drugs (like warfarin or aspirin), diabetes medications, or immunosuppressants. All three drug types have Moderate-severity interactions documented with lion's mane.

Use the medication checker on this page to verify your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Lion's Mane Gummies might appeal to you if you're interested in mushroom supplements and don't take blood thinners, diabetes medications, or immunosuppressants. If you're on any of those drug classes—or any prescription medication at all—check with your pharmacist first.

A conversation with your pharmacist can help you weigh whether this product is right for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lion's Mane Gummies Blueberry Flavored, straight from the product label.

Brand Host Defense Mushrooms
Barcode (UPC) 633422235172
Net contents 90 Gummy(ies)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 335814
Product type Botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gummy(ies)
Maximum serving Sizes:
3 Gummy(ies)
Servings per container
30
UPC/BARCODE
633422235172
IngredientAmount% DV
Calories25 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
Added Sugars4 Gram(s)8%
Total Sugars4 Gram(s)--
Lion's Mane1 Gram(s)--

Other ingredients: Tapioca Syrup, Cane Sugar, Agar, Locust Bean Gum, Natural Flavors, Citric Acid, Vegetable Juice, Monk Fruit extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Paul Stamets Paul Stamets Fungi Perfecti, LLC

Seals/Symbols

Vegan Certified B Corporation

USDA Organic Certified Organic Washington State Department of Agriculture Organic Program

Formulation

Vegan

GF Gluten free

Climate positive

Memory & nerve support

Non GMO

USDA Organic Certified Organic Washington State Department of Agriculture Organic Program Certified Organic by WSDA

Formula

Feeling foggy? Lion's Mane-known as "The Smart Mushroom" is the perfect choice for anyone seeking support for cognition, memory, and focus. Besides promoting brain health, Lion's Mane also supports mood and immune system health.

Made with organic mushroom mycelium Blueberry flavored With other natural flavors

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 3 gummies once per day. Chew thoroughly. Can be taken with food or on an empty stomach or as recommended by your healthcare professional.

Precautions

Caution: If you have a medical condition, are taking medications, or are pregnant or breastfeeding, consult a healthcare professional before using this product.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lion's Mane Gummies Blueberry Flavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Lion's Mane

Interacts with
327 drugs
1 Gram(s) per serving Form: Hericium erinaceus

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane monograph & interactions

Other (inactive) ingredients: Tapioca Syrup, Cane Sugar, Agar, Locust Bean Gum, Natural Flavors, Citric Acid, Vegetable Juice, Monk Fruit extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms Drug Interactions

Want to check YOUR meds against Lion's Mane Gummies Blueberry Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Lion's Mane 327

Individual Drug Interactions

The ingredients in Lion's Mane Gummies Blueberry Flavored interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lion's Mane Gummies Blueberry Flavored interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane

Each ingredient & the kinds of drugs it affects

For each ingredient in Lion's Mane Gummies Blueberry Flavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lion's Mane Gummies Blueberry Flavored, from the product label.

Host Defense Mushrooms

See all Host Defense Mushrooms products
Name
Fungi Perfecti, LLC
Street Address
PO Box 7634
City
Olympia
State
WA
ZipCode
98507
Phone Number
877-504-6926
Web Address
Hostdefense.com
Pharmacist Counseling Corner

Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms: Common Questions

Does Lion's Mane Gummies Blueberry Flavored by Host Defense Mushrooms interact with any medications?
Yes. Based on its ingredients, Lion's Mane Gummies Blueberry Flavored has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lion's Mane Gummies Blueberry Flavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin or aspirin?
You shouldn't without checking with your pharmacist first. Lion's mane may increase bleeding risk when combined with blood thinners or antiplatelet drugs, according to laboratory research. Your pharmacist can review your specific medication and dose to advise you.
What are the side effects?
The most common ones are gastrointestinal discomfort, nausea, and skin rash. These tend to be mild and don't affect most people. If you experience any of these, let your pharmacist know.
Is lion's mane safe to take while pregnant or breastfeeding?
The safety data available advises against it during pregnancy and breastfeeding. There isn't enough research to know either way. Talk with your doctor or pharmacist about what's right for your situation.
Does this actually work for brain health or memory?
The evidence we hold shows insufficient reliable data to say whether lion's mane helps with Alzheimer disease, cognitive function, or cognitive impairment. Some preliminary research exists, but we don't have enough solid human studies yet. Your pharmacist can discuss what's being researched.
What's in these gummies besides lion's mane?
The gummies are sweetened with tapioca syrup and cane sugar, held together with agar and locust bean gum, and flavored with natural flavors and monk fruit extract. Those are all inactive ingredients—fillers and binders to make the gummy.
I'm on diabetes medication. Can I take this?
You'll need to check with your pharmacist first. Lion's mane may lower blood sugar in addition to what your medication does, which could make your glucose drop too low. Your pharmacist can help you decide if it's safe for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lion's Mane Gummies Blueberry Flavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lion's Mane Gummies Blueberry Flavored label
Go deeper

The Full Monographs Behind Lion's Mane Gummies Blueberry Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph →
Sources

Sources & How We Checked

Lion's Mane Gummies Blueberry Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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