Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Liposomal NMN + NR Ingredients & Drug Interactions

by GenuinePurity

Capsule Category: Other Combinations
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Liposomal NMN + NR is a dietary supplement by GenuinePurity with 2 active ingredients. Its ingredients are commonly taken for healthy aging, boosting cellular energy, supporting metabolism.Based on those ingredients, 172 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Nicotinamide Riboside. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Liposomal NMN + NR by GenuinePurity

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has two active ingredients: beta-nicotinamide mononucleotide and nicotinamide riboside. Both are forms of B-vitamin–related compounds that your body can convert to NAD+, a coenzyme involved in cellular energy and aging-related processes.

The formula also contains several inactive ingredients — cellulose, microcrystalline cellulose, maltodextrin, sunflower lecithin, phosphatidylcholine, silicon dioxide, and stearate — which serve as capsule material and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Nicotinamide Riboside's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: healthy aging and cellular energy support.
  • We looked for evidence on: Athletic performance, Physical performance, Cellular metabolism, NAD+ metabolism, Mitochondrial function.
  • The closest evidence on file: Nicotinamide Riboside is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Nicotinamide Riboside is rated "Insufficient Reliable Evidence To Rate" for Physical performance.

The evidence for nicotinamide riboside in this product isn't established yet. We hold insufficient reliable evidence to rate it for age-related macular degeneration, Alzheimer disease, athletic performance, nonalcoholic fatty liver disease, or heart failure — the conditions most commonly studied.

That doesn't mean it doesn't work; it means the clinical data we have isn't strong enough to make a confident claim either way.

The evidence, ingredient by ingredient Nicotinamide Riboside

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Nicotinamide riboside appears well tolerated in short-term studies, but long-term safety isn't fully known. The most common side effects reported in trials are bloating, muscle pain, nausea, itching, sweating, and changes in bowel movements — usually mild and temporary.

One person in a trial reported leg cramps. Because we don't have enough safety data, the evidence advises against use during pregnancy and while breastfeeding.

Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Nicotinamide Riboside

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Nicotinamide Riboside.
  • The most serious interaction on file is rated Minor.
  • For scale: 172 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antihypertensive drugs (blood pressure medications), check with your pharmacist or doctor first — nicotinamide riboside may amplify their effect and lower your blood pressure more than intended. We could not check beta-nicotinamide mononucleotide for interactions, so ask your pharmacist about that ingredient too, especially if you're on multiple prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

This product may appeal to you if you're interested in NAD+ support and aging-related research, though the clinical evidence for its specific health claims isn't yet established. If you take blood pressure medication, check with your pharmacist first — nicotinamide riboside may lower your blood pressure further.

Same goes if you're pregnant or breastfeeding. Run your exact medications through our checker below before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liposomal NMN + NR, straight from the product label.

Brand GenuinePurity
Barcode (UPC) 628043001459
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336118
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liposomal NMN + NR by GenuinePurity, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 VCapsule(s)
Maximum serving Sizes:
2 VCapsule(s)
Servings per container
30
UPC/BARCODE
628043001459
IngredientAmount% DV
Beta-Nicotinamide Mononucleotide250 mg--
Nicotinamide Riboside250 mg--

Other ingredients: Cellulose, Microcrystalline Cellulose, Maltodextrin, Sunflower Lecithin, Phosphatidylcholine, Silicon Dioxide, Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 2 capsules daily preferably with meals or as directed by a healthcare professional.

Precautions

Caution: Do not exceed recommended dose. Do not purchase if seal is broken.

This product is not intended for pregnant or nursing mothers, children under the age of 18, or persons with a known medical condition including any cardiovascular disorder, hypotension (low blood pressure) and Parkinson's disease.

This product is not intended for pregnant or nursing mothers, children under the age of 18, or persons with a known medical condition including any cardiovascular disorder, hypotension (low blood pressure) and Parkinson's disease. Keep out of the reach of children.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg. peanuts, tree nuts, fish, and crustacean shellfish.

Storage

Protect from heat, light and moisture. Store at 15 degrees C-30 degrees C (59-86 degrees F).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Please recycle

Seals/Symbols

Made in USA GMP Sourced from a GMP Certified Facility

Formulation

Promotes Cellular Regeneration, Mitochondrial Function & DNA Health

FDA Statement of Identity

Dietary Supplement

See for yourself

Liposomal NMN + NR by GenuinePurity label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liposomal NMN + NR by GenuinePurity

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 VCapsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Beta-Nicotinamide Mononucleotide

250 mg per serving

Nicotinamide Riboside

Interacts with
172 drugs
250 mg per serving

Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into NAD+, a molecule involved in cellular energy and repair. Early human st...

Nicotinamide Riboside monograph & interactions

Other (inactive) ingredients: Cellulose, Microcrystalline Cellulose, Maltodextrin, Sunflower Lecithin, Phosphatidylcholine, Silicon Dioxide, Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liposomal NMN + NR by GenuinePurity Drug Interactions

Want to check YOUR meds against Liposomal NMN + NR?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
172Drugs
172 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Liposomal NMN + NR with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Nicotinamide Riboside1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
One small clinical study suggests that nicotinamide riboside can modestly reduce blood pressure in hypertensive patients. However, other clinical research did not find a reduction in blood pressure when compared with control.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Liposomal NMN + NR, from the product label.

GenuinePurity

See all GenuinePurity products
Name
GenuinePurity
Street Address
100 Fidelitone Way
City
Elizabethton
State
TN
ZipCode
37643
Web Address
www.GenuinePurity.com
Pharmacist Counseling Corner

Liposomal NMN + NR by GenuinePurity: Common Questions

Does Liposomal NMN + NR by GenuinePurity interact with any medications?
Yes. Based on its ingredients, Liposomal NMN + NR has a known interaction with 172 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liposomal NMN + NR contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Not enough safety data exists, so the evidence advises against it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you in those situations — it's an individual medical decision.
What are the common side effects?
In clinical trials, the most common side effects were bloating, muscle pain, nausea, itching, sweating, and changes in bowel movements. These were usually mild and temporary. One person reported leg cramps.
Does this product actually work?
We don't have strong enough clinical evidence yet to rate nicotinamide riboside for age-related macular degeneration, Alzheimer disease, athletic performance, fatty liver disease, or heart failure. That means the research so far isn't conclusive either way.
What is nicotinamide riboside, and why is it in here?
It's a form of B-vitamin–related compound that your body converts to NAD+, a coenzyme involved in cellular energy and aging processes. It's one of the two active ingredients in this supplement.
Is beta-nicotinamide mononucleotide safe?
We don't hold interaction data for this ingredient, so we can't tell you what it might do alongside your medications. Ask your pharmacist to check it for you, especially if you're on prescriptions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liposomal NMN + NR is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liposomal NMN + NR label
Sources

Sources & How We Checked

Liposomal NMN + NR's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Nicotinamide Riboside 7 references
  1. Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun 2018;9(1):1286. PubMed
  2. Dollerup OL, Christensen B, Svart M, et al. A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. Am J Clin Nutr 2018;108(2):343-53. PubMed
  3. Dellinger RW, Santos SR, Morris M, et al. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safety and sustainably: a randomized, double-blind, placebo-controlled study. NPJ J Aging Mech Dis 2017;3:17.
  4. Conze D, Brenner C, Kruger CL. Safety and metabolism of long-term administration of NIAGEN (nicotinamide riboside chloride) in a randomized, double-blind, placebo-controlled clinical trial of healthy overweight adults. Sci Rep 2019;9(1):9772. PubMed
  5. Remie CME, Roumans KHM, Moonen MPB, et al. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans. Am J Clin Nutr. 2020;112(2):413-426. PubMed
  6. Turck D, Castenmiller J, de Henauw S, et al. Safety of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283 and bioavailability of nicotinamide from this source, in the context of Directive 2002/46/EC. EFSA J. 2019;17(8):e0
  7. EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, et al. Extension of use of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283. EFSA J 2021;19(11):e06843.

See these in context on the Nicotinamide Riboside monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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