Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Lungwort and Coltsfoot Ingredients & Drug Interactions

by Hawaii Pharm

Lungwort and Coltsfoot label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lungwort and Coltsfoot against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lungwort and Coltsfoot is a dietary supplement by Hawaii Pharm with 2 active ingredients. Its ingredients are commonly taken for coughs and chest congestion, sore throat and hoarseness, bronchitis and respiratory complaints.Based on those ingredients, 374 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Coltsfoot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lungwort and Coltsfoot by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Lungwort and Coltsfoot by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Lungwort and Coltsfoot by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: certified organic Lungwort extract and certified organic Coltsfoot extract. Both are herbal extracts in liquid form, suspended in vegetable palm glycerin and alcohol.

The product is labeled as having two active botanical ingredients total.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: respiratory health and cough support.
  • We looked for evidence on: bronchitis, cough, sore throat, congestion.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't have effectiveness data on file for either Lungwort or Coltsfoot in the facts provided to us. The evidence backing their use isn't established in our data, so we can't tell you what they're meant to do or how well they work.

The evidence, ingredient by ingredient Lungwort Coltsfoot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's what you need to know: Coltsfoot is the serious safety concern. It naturally contains liver-toxic compounds called pyrrolizidine alkaloids that can damage your liver and lungs — chronic use has been linked to a condition called veno-occlusive disease, which causes pain, vomiting, fluid buildup, and persistent liver enlargement within weeks.

The facts emphasize using only certified pyrrolizidine-alkaloid-free products, if you use coltsfoot at all. Lungwort has not been well studied for safety in modern research, though it's traditionally used in small amounts in tea.

Neither ingredient should be used during pregnancy or while breastfeeding — the safety data advises against it. If you're pregnant, planning pregnancy, or nursing, do not use this product without talking to your doctor or pharmacist first.

Side effects, ingredient by ingredient Lungwort Coltsfoot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Coltsfoot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on any blood thinners or antiplatelet drugs (aspirin, warfarin, clopidogrel, enoxaparin, heparin, and others) — Coltsfoot can increase bleeding risk. Also flag any drugs that speed up liver metabolism, such as carbamazepine, phenobarbital, phenytoin, rifampin, or rifabutin, as these may activate coltsfoot's toxic alkaloids.

Finally, if you take blood pressure medications, mention this product to your pharmacist, as high doses may interfere with their effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product carries real safety red flags, especially around coltsfoot's liver and lung toxicity. If you're on blood thinners, blood pressure medications, or drugs that speed up liver metabolism, you need to check your exact medications with the tool on this page before considering it.

Talk to your pharmacist — the interaction and toxicity profile here warrants a detailed conversation about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lungwort and Coltsfoot, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 650905462061
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 237522
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lungwort and Coltsfoot by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
650905462061
IngredientAmount% DV
certified organic Lungwort extract250 mcL--
certified organic Coltsfoot extract250 mcL--

Other ingredients: Vegetable Palm Glycerin, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lungwort and Coltsfoot by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lungwort and Coltsfoot label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lungwort and Coltsfoot by Hawaii Pharm

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Certified organic Lungwort extract

No known
interactions
250 mcL per serving

Lungwort (Pulmonaria officinalis) is a traditional European herb long used as a tea for coughs and minor breathing complaints, named for its lung-shap...

Certified organic Lungwort extract monograph & interactions

Certified organic Coltsfoot extract

Interacts with
374 drugs
250 mcL per serving

Coltsfoot is a traditional herb long used to soothe coughs and clear mucus, but solid human evidence for these uses is lacking. More importantly, the...

Certified organic Coltsfoot extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lungwort and Coltsfoot by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Lungwort and Coltsfoot?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
374Drugs
374 Moderate

Ingredients driving the most interactions

certified organic Coltsfoot extract 374

Individual Drug Interactions

The ingredients in Lungwort and Coltsfoot interact with 374 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lungwort and Coltsfoot interact with drugs. Each result below shows which ingredient is responsible. certified organic Coltsfoot extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Lungwort and Coltsfoot with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Coltsfoot extract3 drug types · 374 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use might increase the risk of bleeding due to decreased platelet aggregation. Coltsfoot has been reported to inhibit platelet aggregation; avoid concomitant use. Some of these drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, excessive doses of coltsfoot may interfere with antihypertensive or cardiovascular therapy.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Inducers

Hepatotoxic pyrrolizidine alkaloids (PA) are substrates of cytochrome P450 3A4 (CYP3A4). Theoretically, drugs that induce CYP3A4 might increase the conversion of PAs to toxic metabolites. Some drugs that induce CYP3A4 include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.

Likelihood Possible Evidence D
certified organic Coltsfoot extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lungwort and Coltsfoot, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Lungwort and Coltsfoot by Hawaii Pharm: Common Questions

Does Lungwort and Coltsfoot by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Lungwort and Coltsfoot has a known interaction with 374 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lungwort and Coltsfoot contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to use during pregnancy or while breastfeeding?
No. The safety data advises against both ingredients during pregnancy and lactation. Coltsfoot carries particular risk because its toxic alkaloids can harm the baby and pass into breast milk. Do not use this product if you're pregnant, planning to become pregnant, or breastfeeding without talking to your doctor or pharmacist first.
What are pyrrolizidine alkaloids, and why should I care?
Pyrrolizidine alkaloids (PAs) are naturally occurring toxic compounds in coltsfoot. They can damage your liver and lungs, and chronic exposure has been linked to a serious condition that causes pain, vomiting, fluid buildup, and liver enlargement. The facts stress that you should only use certified PA-free coltsfoot products, if at all.
I'm on a blood thinner like warfarin. Can I take this?
Not without checking with your pharmacist first. Coltsfoot may interfere with how your blood clots work and increase bleeding risk. Run your exact medication through the interaction checker on this page before starting this product.
How much of this product is actually herbal extract versus filler?
The facts tell us this is a liquid product with two active herbal extracts in vegetable palm glycerin and alcohol as the base, but we don't have a breakdown of the exact percentages or doses of each extract.
What is Lungwort supposed to do?
We don't have effectiveness information on file for Lungwort. The evidence backing its use isn't documented in our data, so we can't tell you what it's meant to treat or how well it works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lungwort and Coltsfoot is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lungwort and Coltsfoot label
Go deeper

The Full Monographs Behind Lungwort and Coltsfoot’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lungwort

Lungwort (Pulmonaria officinalis) is a traditional European herb long used as a tea for coughs and minor breathing complaints, named for its lung-shaped, spotted leaves. There is very little...

Read the full Lungwort monograph → Herb & supplement monograph

Coltsfoot

Interacts with 374 drugs

Coltsfoot is a traditional herb long used to soothe coughs and clear mucus, but solid human evidence for these uses is lacking. More importantly, the raw plant can contain liver-toxic pyrrol...

Read the full Coltsfoot monograph →
Sources

Sources & How We Checked

Lungwort and Coltsfoot's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lungwort 1 reference
  1. Pyrrolizidine Alkaloids — NIH LiverTox Source

See these in context on the Lungwort monograph →

Coltsfoot 8 references
  1. Roulet M, Laurini R, Rivier L, Calame A. Hepatic veno-occlusive disease in newborn infant of a woman drinking herbal tea. J Pediatr 1988;112:433-6. PubMed
  2. WHO working group. Pyrrolizidine alkaloids. Environmental Health Criteria, 80. WHO: Geneva, 1988.
  3. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  4. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  5. Wilson BE, Hobbs WN. Case report: pseudoephedrine-associated thyroid storm: thyroid hormone-catecholamine interactions. Am J Med Sci 1993;306:317-9. PubMed
  6. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  7. Hwang SB, Chang MN, Garcia ML, et al. L-652,469--a dual receptor antagonist of platelet activating factor and dihydropyridines from Tussilago farfara L. Eur J Pharmacol 1987;141:269-81. PubMed
  8. Freshour JE, Odle B, Rikhye S, Stewart DW. Coltsfoot as a potential cause of deep vein thrombosis and pulmonary embolism in a patient also consuming kava and blue vervain. J Diet Suppl 2012;9:149-54. PubMed

See these in context on the Coltsfoot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team