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Dietary supplement

Maitake Mushroom 1000 mg Ingredients & Drug Interactions

by Remedys Nutrition

Maitake Mushroom 1000 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Maitake Mushroom 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Maitake Mushroom 1000 mg is a dietary supplement by Remedys Nutrition with 1 active ingredient. Its ingredients are commonly taken for immune support, blood sugar support in diabetes, high blood pressure.Based on those ingredients, 260 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Maitake Mushroom. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Maitake Mushroom 1000 mg by Remedys Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Maitake Mushroom 1000 mg by Remedys Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Maitake Mushroom 1000 mg by Remedys Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: organic maitake mushroom at 1000 mg per capsule. Maitake is a medicinal mushroom used in traditional practice; the supplement extracts its active compounds, called polysaccharides, which are the components studied in clinical research.

The capsule itself is made from a vegan capsule material (an inactive ingredient).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Maitake Mushroom product and its label doesn't state a use — see Maitake Mushroom's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish how well maitake mushroom works for any particular condition. It's been studied for allergic rhinitis (hay fever), chemotherapy-related side effects like anemia and diarrhea, laryngeal cancer, and chronic fatigue syndrome, but the data we have rates all of these as insufficient — meaning the evidence isn't strong or complete enough to draw a conclusion.

If you're considering it for a specific health goal, that's worth discussing with your doctor or pharmacist.

The evidence, ingredient by ingredient Maitake Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maitake mushroom is generally well tolerated when eaten as food, but the safety of concentrated supplements hasn't been fully studied. The most common side effects in clinical trials were gastrointestinal — mild stomach discomfort, diarrhea, and nausea.

A small number of trial participants reported these; one person withdrew from a study because of diarrhea, and one reported a rash and itching (an allergic reaction) that cleared on its own. The safety data advises against using concentrated maitake supplements during pregnancy and while breastfeeding because there isn't enough information to know they're safe.

Side effects, ingredient by ingredient Maitake Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Maitake Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 260 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you're on warfarin or other blood thinners, blood pressure medications, or diabetes drugs — all carry Moderate-severity interaction risk with maitake mushroom. Your doctor may want to monitor your blood pressure, blood glucose, or INR more closely if you combine them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're on blood pressure medication, diabetes medication, or warfarin, you'll need to check with your doctor or pharmacist before adding this supplement — the interactions are real, even if they're not guaranteed to cause harm. For other medications, run them through the tool on this page.

Maitake is generally well tolerated, though stomach upset can happen. Talk it over with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maitake Mushroom 1000 mg, straight from the product label.

Brand Remedys Nutrition
Barcode (UPC) 672299450424
Net contents 60 Vcap(s)
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 241491
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maitake Mushroom 1000 mg by Remedys Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegan Capsule(s)
Maximum serving Sizes:
1 Vegan Capsule(s)
Servings per container
60
UPC/BARCODE
672299450424
IngredientAmount% DV
organic Maitake Mushroom1000 mg--

Other ingredients: Vegan Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: One capsule daily

Formulation

Made in the U.S.A.

Non-GMO Gluten free No additives No preservatives No dairy No yeast No corn No fillers

Vegan

Quality and potency guaranteed

Cellular health Sugar Pressure Pharmacist approved

Precautions

Caution: As with any dietary supplement, consult your healthcare practitioner before using this product.

Keep out of reach of children.

Adult use only

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, or prevent any disease.

General Statements

Remedys Nutrition Est. 1972 Quality Purity Pride Two month supply

Scan here to learn more:

Formula

Maitake Mushroom 1000 mg per capsule 60000 mg per bottle

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Maitake Mushroom 1000 mg by Remedys Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Maitake Mushroom 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Maitake Mushroom 1000 mg by Remedys Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegan Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Organic Maitake Mushroom

Interacts with
260 drugs
1000 mg per serving

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and bl...

Organic Maitake Mushroom monograph & interactions

Other (inactive) ingredients: Vegan Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maitake Mushroom 1000 mg by Remedys Nutrition Drug Interactions

Want to check YOUR meds against Maitake Mushroom 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
260Drugs
260 Moderate

Ingredients driving the most interactions

organic Maitake Mushroom 260

Individual Drug Interactions

The ingredients in Maitake Mushroom 1000 mg interact with 260 drugs. Click any drug to see the details.

1 of the 1 ingredient in Maitake Mushroom 1000 mg interact with drugs. Each result below shows which ingredient is responsible. organic Maitake Mushroom

Each ingredient & the kinds of drugs it affects

For each ingredient in Maitake Mushroom 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Maitake Mushroom3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
organic Maitake Mushroom full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Maitake Mushroom 1000 mg, from the product label.

Remedys Nutrition

See all Remedys Nutrition products
Name
Remedy's Nutrition
Street Address
99696 Overseas Highway Ste 6
City
Key Largo
State
FL
ZipCode
33037
Web Address
www.RMDYS.com
Pharmacist Counseling Corner

Maitake Mushroom 1000 mg by Remedys Nutrition: Common Questions

Does Maitake Mushroom 1000 mg by Remedys Nutrition interact with any medications?
Yes. Based on its ingredients, Maitake Mushroom 1000 mg has a known interaction with 260 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Maitake Mushroom 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it. There isn't enough information to know whether concentrated maitake supplements are safe during pregnancy or while breastfeeding, so talk with your doctor or pharmacist before using it if you're in either situation.
What's maitake mushroom supposed to do?
Maitake has been studied for allergic rhinitis (hay fever), side effects from chemotherapy, and chronic fatigue syndrome, but we don't have strong enough evidence yet to say how well it works for any of these. That doesn't mean it won't help — just that more research is needed.
What are the side effects?
Most people tolerate it well. The main ones reported in studies were stomach upset — diarrhea, nausea, and mild epigastric discomfort. A very small number of people reported a rash and itching that went away on its own.
Is this safe if I'm not on any medications?
For most people not taking medications that interact with it, maitake is generally well tolerated. Just keep in mind that concentrated supplement safety hasn't been fully studied the way foods are. If you develop stomach upset or any other unusual symptoms, stop and talk with your pharmacist.
Why does this interact with so many drugs?
The 260 medications affected come from just three drug categories: blood pressure medications, diabetes medications, and warfarin. Those are large groups with many options in each, which adds up the count. The real concern is whether YOU take any of those types.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maitake Mushroom 1000 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maitake Mushroom 1000 mg label
Go deeper

The Full Monographs Behind Maitake Mushroom 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph →
Sources

Sources & How We Checked

Maitake Mushroom 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maitake Mushroom 8 references
  1. Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
  2. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. PubMed
  3. Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. PubMed
  4. Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Compl
  5. Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. PubMed
  6. Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. PubMed
  7. Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., and Cassileth, B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: i
  8. Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. PubMed

See these in context on the Maitake Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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