Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Malic Acid 600 mg Ingredients & Drug Interactions

by Swanson Premium Brand

Malic Acid 600 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Malic Acid 600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Malic Acid 600 mg is a dietary supplement by Swanson Premium Brand with 1 active ingredient. Its ingredients are commonly taken for fibromyalgia symptoms, muscle pain and fatigue, dry mouth (used in some lozenges).Based on those ingredients, 172 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Malic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Malic Acid 600 mg by Swanson Premium Brand

Ask about any prescription or over-the-counter medication and we check it for interactions with Malic Acid 600 mg by Swanson Premium Brand — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Malic Acid 600 mg by Swanson Premium Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-malic acid, 600 mg per capsule. Malic acid is an organic compound found naturally in fruits and other foods.

The capsule also contains inactive ingredients (hypromellose, silica, calcium palmitate, and microcrystalline cellulose) that help form and fill the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Malic Acid's overall clinical evidence instead.

Moderate

Some clinical evidence supports Malic Acid for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dry mouth — rated "Possibly Effective" (Natural Medicines).

Malic acid is possibly effective for dry mouth. For acne, gastroesophageal reflux disease (GERD), fatigue, fibromyalgia, and psoriasis, the evidence isn't established in the data we hold—there just isn't enough reliable research to say whether it works or not.

The evidence, ingredient by ingredient Malic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Malic acid from food is generally well tolerated. At supplement doses like the 600 mg in this product, though, safety hasn't been well studied.

The facts advise caution and suggest avoiding supplement doses unless your doctor recommends it. When malic acid is taken by mouth, it seems well tolerated overall; diarrhea and nausea have been reported in patients taking a combination product with malic acid and magnesium, though it's unclear which ingredient caused those effects.

Topically (on skin), malic acid can cause skin irritation, peeling, and in some cases hives or contact dermatitis.

Side effects, ingredient by ingredient Malic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Malic Acid.
  • The most serious interaction on file is rated Moderate.
  • For scale: 172 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any blood pressure-lowering medications (antihypertensive drugs). Malic acid may increase the risk of blood pressure dropping too low.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Malic acid is possibly effective for dry mouth, though evidence for other uses isn't established. The main concern is its potential to lower blood pressure alongside antihypertensive medications.

Because supplement-dose safety isn't well studied, talk with your doctor or pharmacist about whether this product is right for you, especially if you take blood pressure medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Malic Acid 600 mg, straight from the product label.

Brand Swanson Premium Brand
Barcode (UPC) 087614019390
Net contents 100 Veggie Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 212687
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Malic Acid 600 mg by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614019390
IngredientAmount% DV
L-Malic Acid600 mg--

Other ingredients: Hypromellose, Silica, Calcium Palmitate, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bringing wellness to the world since 1969

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

FDA Statement of Identity

Dietary Supplement

Formulation

Vegetarian Formula

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one veggie capsule two times per day with water.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Malic Acid 600 mg by Swanson Premium Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Malic Acid 600 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Malic Acid 600 mg by Swanson Premium Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

L-Malic Acid

Interacts with
172 drugs
600 mg per serving

Malic acid is a natural acid found in apples and other fruits, often combined with magnesium in supplements marketed for fibromyalgia and muscle pain....

L-Malic Acid monograph & interactions

Other (inactive) ingredients: Hypromellose, Silica, Calcium Palmitate, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Malic Acid 600 mg by Swanson Premium Brand Drug Interactions

Want to check YOUR meds against Malic Acid 600 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
172Drugs
172 Moderate

Ingredients driving the most interactions

L-Malic Acid 172

Individual Drug Interactions

The ingredients in Malic Acid 600 mg interact with 172 drugs. Click any drug to see the details.

1 of the 1 ingredient in Malic Acid 600 mg interact with drugs. Each result below shows which ingredient is responsible. L-Malic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Malic Acid 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Malic Acid1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, malic acid might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that malic acid isolated from tagetes roots can reduce mean arterial blood pressure.

Likelihood Possible Evidence D
L-Malic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Malic Acid 600 mg, from the product label.

Swanson Premium Brand

See all Swanson Premium Brand products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Malic Acid 600 mg by Swanson Premium Brand: Common Questions

Does Malic Acid 600 mg by Swanson Premium Brand interact with any medications?
Yes. Based on its ingredients, Malic Acid 600 mg has a known interaction with 172 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Malic Acid 600 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is malic acid safe during pregnancy or while breastfeeding?
Malic acid is rated likely safe during pregnancy and lactation. That said, if you're pregnant or nursing, it's smart to confirm with your doctor or pharmacist before starting any supplement.
What side effects might I experience taking this?
Taken by mouth, malic acid is generally well tolerated. Diarrhea and nausea have been reported in people taking a supplement combining malic acid with magnesium, though it's unclear which ingredient caused those effects. Supplement-dose safety overall hasn't been thoroughly studied.
Will this help my dry mouth?
Malic acid is possibly effective for dry mouth, so it may help—but the evidence isn't strong. Talk with your doctor about whether it's worth trying for your situation.
Can I take this if I have GERD or fibromyalgia?
The evidence for malic acid in GERD and fibromyalgia isn't established in our data. There just isn't enough reliable research to say whether it works or not. Your doctor or pharmacist can help you decide if it's worth trying.
What are the inactive ingredients?
The capsule contains hypromellose, silica, calcium palmitate, and microcrystalline cellulose—all inactive ingredients that form and fill the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Malic Acid 600 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Malic Acid 600 mg label
Go deeper

The Full Monographs Behind Malic Acid 600 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Malic Acid

Interacts with 172 drugs

Malic acid is a natural acid found in apples and other fruits, often combined with magnesium in supplements marketed for fibromyalgia and muscle pain. The evidence for its health benefits is...

Read the full Malic Acid monograph →
Sources

Sources & How We Checked

Malic Acid 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Malic Acid 7 references
  1. Russell IJ, Michalek JE, Flechas JD, Abraham GE. Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study. J Rheumatol 1995;22:953-8.
  2. Fiume, Z. Final report on the safety assessment of malic acid and sodium malate. Int J Toxicol 2001;20 Suppl 1:47-55. PubMed
  3. Electronic Code of Federal Regulations. Title 21. Part 184 - Direct Food Substances Affirmed as Generally Recognized as Safe. Available at: http://www.ecfr.gov/cgi-bin/text-idx?c=ecfr&sid=786bafc6f6343634fbf79fcdca7061e1&rgn=div5&view=text&node=21:3.0.1.1
  4. Saleem R, Ahmad M, Naz A, et al. Hypotensive and toxicological study of citric acid and other constituents from Tagetes patula roots. Arch Pharm Res 2004;27(10):1037-42.
  5. Chiriac A, Brzezinski P. Topical malic acid in combination with citric acid: an option to treat recalcitrant warts. Dermatol Ther. 2015;28(6):336-8. PubMed
  6. CFR - Code of Federal Regulations Title 21 SUBCHAPTER B. 184.1069 Malic Acid. Food and Drug Administration Department Of Health And Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1069.
  7. Amended Safety Assessment of Malic Acid and Sodium Malate as Used in Cosmetics. Cosmetic Ingredient Review Expert Panel. Updated May 19, 2017. http://www.cir-safety.org/sites/default/files/malic%20acid.pdf. Accessed January 24, 2018.

See these in context on the Malic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team