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Dietary supplement

Maximum Beta Glucan 400 mg Ingredients & Drug Interactions

by Supplement Spot

Maximum Beta Glucan 400 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Maximum Beta Glucan 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Maximum Beta Glucan 400 mg is a dietary supplement by Supplement Spot with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pureglucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Maximum Beta Glucan 400 mg by Supplement Spot

Ask about any prescription or over-the-counter medication and we check it for interactions with Maximum Beta Glucan 400 mg by Supplement Spot — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Maximum Beta Glucan 400 mg by Supplement Spot

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Pureglucan” is listed as a grouped ingredient — the label gives one combined amount (400 mg) without saying how much of each component you get.

This product contains one active ingredient: beta-glucans (specifically beta 1,3/1,6 glucan), supplied as Pureglucan at 400 mg per capsule. Beta-glucans are a type of fiber found naturally in foods like oats, barley, and certain mushrooms, and they're the ingredient studied for effects on cholesterol and heart health.

The capsule also contains gelatin, stabilized rice bran, and magnesium stearate as inactive ingredients (binders and capsule material).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy immune function.
  • We looked for evidence on: Exercise-induced respiratory infections, Lower respiratory tract infections, Otitis media, Upper respiratory tract infection (URTI), Critical illness (trauma), Wound healing — and 3 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections, Lower respiratory tract infections, Otitis media, Wound healing, and more.

Beta-glucans are likely effective for lowering cholesterol (dyslipidemia) and supporting heart health in coronary heart disease. The evidence we hold is based on clinical research showing real benefit in these areas, though results vary from person to person.

We don't have effectiveness data on other conditions.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated. However, concentrated supplements like this one lack robust safety data, so use caution—this is a reminder that "supplement dose" doesn't mean the same evidence backs it as food amounts do.

Side effects are uncommon when taken by mouth. There isn't enough research on supplement doses during breastfeeding to know whether they're safe, so talk with your doctor or pharmacist if you're nursing.

We hold no pregnancy safety data for this ingredient.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your doctor or pharmacist if you take blood pressure medications (antihypertensives) or drugs that suppress your immune system (immunosuppressants). Beta-glucans may lower blood pressure further or interfere with immune-suppressing therapy.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking to support cholesterol and heart health, beta-glucans have solid evidence behind them. But if you take blood pressure medication or immunosuppressants, you'll need to check with your doctor or pharmacist first — the interaction potential is real.

And since concentrated supplement doses haven't been studied as thoroughly as food sources, starting a conversation with your healthcare provider is smart.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maximum Beta Glucan 400 mg, straight from the product label.

Brand Supplement Spot
Barcode (UPC) 617375775954
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 264629
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maximum Beta Glucan 400 mg by Supplement Spot, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
30
UPC/BARCODE
617375775954
IngredientAmount% DV
Pureglucan400 mg--
Beta 1,3/1,6 Glucan0 NP--

Other ingredients: Gelatin, stabilized Rice Bran, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take 2 capsules daily with food and water. May take up to 4 capsules daily, as needed. Take consistently each day for best results.

Precautions

Note: If you are pregnant or lactating, consult a healthcare professional before using this product.

Keep out of reach of children.

Do not use this product if the safety seal on the bottle is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Supports healthy immune function

FDA Statement of Identity

Dietary Supplement

Formula

Maximum Beta Glucan 400 mg per serving

Seals/Symbols

Formulated in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Maximum Beta Glucan 400 mg by Supplement Spot label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Maximum Beta Glucan 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Maximum Beta Glucan 400 mg by Supplement Spot

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Pureglucan

Interacts with
293 drugs
400 mg per serving Form: Beta-Glucan

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Pureglucan monograph & interactions

Other (inactive) ingredients: Gelatin, Stabilized Rice Bran, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maximum Beta Glucan 400 mg by Supplement Spot Drug Interactions

Want to check YOUR meds against Maximum Beta Glucan 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Pureglucan 293

Individual Drug Interactions

The ingredients in Maximum Beta Glucan 400 mg interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Maximum Beta Glucan 400 mg interact with drugs. Each result below shows which ingredient is responsible. Pureglucan

Each ingredient & the kinds of drugs it affects

For each ingredient in Maximum Beta Glucan 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pureglucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Pureglucan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Maximum Beta Glucan 400 mg, from the product label.

Supplement Spot

See all Supplement Spot products
Name
Supplement Spot, LLC
Street Address
1828 Touby Pike
City
Kokomo
State
IN
ZipCode
46901
Phone Number
866-285-1998
Web Address
supplementspot.com
Pharmacist Counseling Corner

Maximum Beta Glucan 400 mg by Supplement Spot: Common Questions

Does Maximum Beta Glucan 400 mg by Supplement Spot interact with any medications?
Yes. Based on its ingredients, Maximum Beta Glucan 400 mg has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Maximum Beta Glucan 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does beta-glucan actually do?
Beta-glucan is a type of fiber that's been studied for supporting heart and cholesterol health. The evidence shows it's likely effective for lowering cholesterol and helping with coronary heart disease.
Will beta-glucans cause side effects?
When taken by mouth, beta-glucans are generally well tolerated and most people don't report problems. The research we hold doesn't describe common side effects from oral use at supplement doses.
Is this safe if I'm breastfeeding?
There isn't enough research on supplement doses of beta-glucans during breastfeeding to know either way. Talk with your doctor or pharmacist about whether this is right for you while nursing.
What's in the capsule besides beta-glucan?
The capsule contains gelatin, stabilized rice bran, and magnesium stearate—these are inactive ingredients used to hold the supplement together and as a capsule material.
Why do I need to be careful about blood pressure medication?
Beta-glucans can lower blood pressure on their own. If you're already taking medication to lower blood pressure, combining them might drop your blood pressure too much, which is why your doctor needs to know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maximum Beta Glucan 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maximum Beta Glucan 400 mg label
Go deeper

The Full Monographs Behind Maximum Beta Glucan 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Maximum Beta Glucan 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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