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Dietary supplement

Maximum Potency Horny Goat Weed Extract 300 mg Ingredients & Drug Interactions

by Swanson Superior Herbs

Maximum Potency Horny Goat Weed Extract 300 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Maximum Potency Horny Goat Weed Extract 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Maximum Potency Horny Goat Weed Extract 300 mg is a dietary supplement by Swanson Superior Herbs with 1 active ingredient. Its ingredients are commonly taken for erectile dysfunction, low libido, fatigue and low energy.Based on those ingredients, 963 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horny Goat Weed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Horny Goat Weed extract at 300 mg per capsule. It also includes inactive ingredients — rice extract, hypromellose (a capsule material), and rice concentrate — which help form and fill the capsule.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Support sexual function and vitality.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, Fatigue, Postmenopausal conditions, Libido, Energy — and 1 related terms.
  • The closest evidence on file: Horny Goat Weed is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Horny Goat Weed is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Fatigue, Postmenopausal conditions.

The evidence for horny goat weed is not established in our data. For sexual dysfunction, osteoporosis, bronchitis, and coronary heart disease, we have insufficient reliable evidence to rate how well it works.

This doesn't mean it's ineffective — just that we don't have strong human trial data backing its use for these conditions.

The evidence, ingredient by ingredient Horny Goat Weed

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of horny goat weed seems to be generally well tolerated, but human safety data is limited and product quality varies. The most common side effects are dizziness, dry mouth, nosebleed, thirst, and vomiting.

Long-term use has been linked to vomiting, dry mouth, thirst, and nosebleed. One rare case reported a heart rhythm problem (tachyarrhythmia) in a man with heart disease, though we can't be sure horny goat weed caused it.

During pregnancy, safety data advises against use — it's rated possibly unsafe. While breastfeeding, there isn't enough data to know either way, so talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Horny Goat Weed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horny Goat Weed.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 964 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your blood thinners or antiplatelet drugs (like warfarin or aspirin), blood pressure medications, estrogen or hormonal birth control, and any medication your liver breaks down via CYP1A2, CYP2B6, or CYP3A4 pathways. All of these have documented moderate interactions in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Horny goat weed extract is worth considering if you're interested in trying it for sexual function or bone health, but understand the evidence is still limited. If you take blood thinners, blood pressure meds, hormonal birth control, or medications processed by your liver, you should check with your pharmacist first — the interaction potential is real.

Avoid it in pregnancy, and talk with your doctor before use if you're breastfeeding or have heart disease.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maximum Potency Horny Goat Weed Extract 300 mg, straight from the product label.

Brand Swanson Superior Herbs
Barcode (UPC) 087614142494
Net contents 30 Veggie Capsule(s)
Market status Off market
Date entered into DSLD Aug 31, 2018
DSLD ID 180586
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614142494
IngredientAmount% DV
Horny Goat Weed extract300 mg--

Other ingredients: Rice extract, Hypromellose, Rice concentrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Standardized Herbal Supplement

Formula

50% Icariins

Seals/Symbols

V Vegetarian formula Guaranteed purity & potency

Formulation

V Vegetarian formula

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Warning: Consult your healthcare provider before use if you are taking prescription medication or if you are pregnant or nursing.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one veggie capsule one to two times per day between meals, with water.

General Statements

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

General

SWH249 Rev 0 01 31 18

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Maximum Potency Horny Goat Weed Extract 300 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Horny Goat Weed extract

Interacts with
963 drugs
300 mg per serving Form: Icariin

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these...

Horny Goat Weed extract monograph & interactions

Other (inactive) ingredients: Rice extract, Hypromellose, Rice concentrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs Drug Interactions

Want to check YOUR meds against Maximum Potency Horny Goat Weed Extract 300 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
963Drugs
963 Moderate

Ingredients driving the most interactions

Horny Goat Weed extract 963

Individual Drug Interactions

The ingredients in Maximum Potency Horny Goat Weed Extract 300 mg interact with 963 drugs. Click any drug to see the details.

1 of the 1 ingredient in Maximum Potency Horny Goat Weed Extract 300 mg interact with drugs. Each result below shows which ingredient is responsible. Horny Goat Weed extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Maximum Potency Horny Goat Weed Extract 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horny Goat Weed extract6 drug types · 963 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, horny goat weed might increase the risk of bleeding.
In vitro research and animal research shows that horny goat weed can inhibit platelet aggregation and thrombus formation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, horny goat weed might increase the risk of hypotension.
Laboratory research suggests that horny goat weed might have hypotensive effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP1A2 substrates.
In vitro, horny goat weed leaf extract inhibits CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP2B6 substrates.
In vitro, horny goat weed leaf extract inhibits CYP2B6. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.
In vitro, horny goat weed extract inhibits CYP3A4 and suppresses CYP3A4 mRNA expression. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of horny goat weed with estrogens might increase their therapeutic and adverse effects.
In vitro evidence suggests that horny goat weed has estrogenic activity. In clinical research, horny goat weed has been shown to increase blood levels of estrogen in some females.

Likelihood Possible Evidence D
Horny Goat Weed extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Maximum Potency Horny Goat Weed Extract 300 mg, from the product label.

Swanson Superior Herbs

See all Swanson Superior Herbs products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs: Common Questions

Does Maximum Potency Horny Goat Weed Extract 300 mg by Swanson Superior Herbs interact with any medications?
Yes. Based on its ingredients, Maximum Potency Horny Goat Weed Extract 300 mg has a known interaction with 963 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Maximum Potency Horny Goat Weed Extract 300 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is horny goat weed safe to take while I'm on birth control?
Horny goat weed may theoretically increase estrogen levels in your body, which could affect how your hormonal birth control works or boost its side effects. You should check with your pharmacist or doctor before adding this to your routine.
What are the side effects I might notice?
The most common ones are dizziness, dry mouth, nosebleed, thirst, and vomiting. These tend to show up with short-term use. If you use it longer, dry mouth, thirst, nosebleed, and vomiting have been reported. Stop and talk to your pharmacist if anything feels off.
Can I take this while pregnant or breastfeeding?
During pregnancy, there isn't enough safety data — avoid it. While breastfeeding, the data isn't there either way, so talk with your doctor or pharmacist about whether it's right for you before starting.
Does horny goat weed actually work for sexual dysfunction?
We don't have reliable evidence yet to say how well it works. The data we hold rates it as having insufficient evidence — meaning more research is needed before we can call it effective or ineffective.
Will this interfere with my blood pressure or heart medications?
Possibly. Horny goat weed may theoretically lower blood pressure further and interfere with how your liver processes certain heart drugs. If you take either type of medication, check with your pharmacist before starting this supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maximum Potency Horny Goat Weed Extract 300 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maximum Potency Horny Goat Weed Extract 300 mg label
Go deeper

The Full Monographs Behind Maximum Potency Horny Goat Weed Extract 300 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horny Goat Weed

Interacts with 963 drugs

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these uses is lacking. While short-term use s...

Read the full Horny Goat Weed monograph →
Sources

Sources & How We Checked

Maximum Potency Horny Goat Weed Extract 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horny Goat Weed 11 references
  1. Cirigliano MD, Szapary PO. Horny goat weed for erectile dysfunction. Alt Med Alert 2001;4:19-22.
  2. Partin JF, Pushkin YR. Tachyarrhythmia and hypomania with horny goat weed. Psychosomatics 2004;45:536-7. PubMed
  3. De Naeyer A, Pocock V, Milligan S, De Keukeleire D. Estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum. Fitoterapia 2005;76:35-40. PubMed
  4. Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
  5. Yap SP, Shen P, Li J, et al. Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium. J Ethnopharmacol 2007;113:218-24. PubMed
  6. Yan, F. F., Liu, Y., Liu, Y. F., and Zhao, Y. X. Herba Epimedii water extract elevates estrogen level and improves lipid metabolism in postmenopausal women. Phytother.Res. 2008;22(9):1224-1228. PubMed
  7. Ramanathan VS, Mitropoulos E, Shlopov B, et al. An Enzyte'ing' case of acute hepatitis. J Clin Gastroenterol 2011;45(9):834-5. PubMed
  8. Zhong Q, Shi Z, Zhang L, et al. The potential of Epimedium koreanum Nakai for herb-drug interaction. J Pharm Pharmacol 2017;69(10):1398-408. doi: 10.1111/jphp.12773.
  9. Irfan M, Kwon TH, Lee DH, et al. Antiplatelet and Antithrombotic Effects of Epimedium koreanum Nakai. Evid Based Complement Alternat Med. Apr 2021;2021:7071987. PubMed
  10. Tan K, Yang W, Pang L, Hou F. Differences in clinical characteristics among 726 patients with Chinese herbal medicine- or Western medicine-induced liver injury. Medicine (Baltimore) 2022;101(32):e29909. PubMed
  11. Li K, Yu XH, Maskey AR, et al. Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid. Front Pharmacol 2023;13:1042756. PubMed

See these in context on the Horny Goat Weed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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