Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor Ingredients & Drug Interactions

by Aurora NutraScience

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor is a dietary supplement by Aurora NutraScience with 4 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 412 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin C, Sodium, Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience

Ask about any prescription or over-the-counter medication and we check it for interactions with Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid supplement contains 4 active ingredients: sodium, vitamin C, coenzyme Q10 (CoQ10), and PQQ. Sodium is an essential mineral that helps maintain fluid balance and nerve function, though the product's sodium content is the primary concern with certain medications.

Vitamin C is an antioxidant and immune support nutrient. Coenzyme Q10 is a compound your body produces naturally and uses for cellular energy and heart health.

The product also includes inactive ingredients such as water, soy lecithin, glycerin, natural flavors, xanthan gum, stevia leaf extract, sodium citrate, and potassium sorbate.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Cellular support and antioxidant health.
  • We looked for evidence on: Aging, Coenzyme Q10 deficiency, Fatigue, Cardiovascular disease (CVD), Congestive heart failure, Congestive heart failure (CHF) — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Likely Effective" for Coenzyme Q10 deficiency (Natural Medicines).
  • Also on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF).
  • Also on file: Vitamin C is rated "Possibly Effective" for Atrial fibrillation.

Sodium is Likely Effective for cystic fibrosis and Possibly Effective for amphotericin B–related kidney damage, though evidence for other conditions like bipolar disorder and heart failure is insufficient. Vitamin C is Effective for vitamin C deficiency and Possibly Effective for anemia of chronic disease, atrial fibrillation, cataracts, and respiratory infections from exercise.

Coenzyme Q10 is Likely Effective for CoQ10 deficiency and Possibly Effective for fibromyalgia, migraine headache, heart failure, and diabetic nerve pain. We hold no effectiveness data for PQQ.

The evidence, ingredient by ingredient Sodium Vitamin C Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin C is generally well tolerated at normal doses but can cause abdominal cramps, heartburn, diarrhea, nausea, and kidney stones — especially above 2 grams daily — in those prone to kidney stones. Coenzyme Q10 is generally well tolerated; the most common side effects are mild gastrointestinal discomfort like nausea, diarrhea, and heartburn, occurring in less than 1% of users.

Sodium is essential in small amounts, but high intake is linked to high blood pressure and heart strain; normal dietary amounts are fine, but avoid sodium supplements or very high intake without medical advice. Pregnancy and lactation safety data exist for sodium and vitamin C (both Likely Safe in pregnancy, though vitamin C is Possibly Unsafe in breastfeeding); we hold no pregnancy or breastfeeding data for coenzyme Q10 or PQQ.

Side effects, ingredient by ingredient Sodium Vitamin C Coenzyme Q10

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Coenzyme Q10, Vitamin C, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; lithium.
  • For scale: 412 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check blood pressure medications (antihypertensives) and blood thinners (warfarin) first — both carry Moderate interactions. Also check if you take corticosteroids, lithium, thyroid medication (levothyroxine), chemotherapy drugs (alkylating agents or antitumor antibiotics), estrogen-based contraceptives, didanosine, sodium phosphate, or tolvaptan.

All have documented Moderate (or in the case of antihypertensives with CoQ10, Minor) interactions with one or more of this product's ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're deficient in any of its active ingredients and have no blood pressure or blood-thinning medications. If you take blood pressure drugs, blood thinners like warfarin, thyroid medication, lithium, chemotherapy, corticosteroids, or estrogen-based contraceptives, check your exact medications with the tool on this page before starting.

Talk to your pharmacist about the sodium content and whether it fits your dietary intake goals.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor, straight from the product label.

Brand Aurora NutraScience
Barcode (UPC) 628504648025
Net contents 16 Fluid Ounce(s); 480 Milliliter(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 276654
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
32
UPC/BARCODE
628504648025
IngredientAmount% DV
Sodium10 mg1%
Total Fat0.5 Gram(s)1%
Vitamin C180 mg200%
Calories5 Calorie(s)--
Coenzyme Q10300 mg--
PQQ30 mg--

Other ingredients: Water, Purified, Soy Lecithin, Glycerin, Natural Flavors, Xantham Gum, Stevia leaf extract, Sodium Citrate, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Cellular support complex plus vitamin C

Why use Mega-Liposomal CoQ10/PQQ+? Our Mega-Liposomal CoQ10/PQQ+ nutrients are encapsulated into all-natural lipospheres. This helps protect the nutrients while facilitating a more efficient transition through the digestive system and into the body's bloodstream. We use only 100% organic fruit flavoring and natural stevia leaf extract to give our product a great taste that everyone can enjoy!

Formulation

Liposomal delivery technology

Gluten free Non GMO ingredients Sugar free

We use only 100% organic fruit flavoring and natural stevia leaf extract to give our product a great taste that everyone can enjoy!

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Shake gently

As a dietary supplement, take 1 tablespoon (15mL) daily or as directed by your healthcare professional. Shake gently before each use. Take anytime, preferably on an empty stomach. Drink straight or with cold water, juice or yogurt. Do not high speed machine blend.

Best if consumed within 45 days of opening.

Storage

Refrigerate after opening

Store in cool dry place away from heat or direct sunlight. Refrigerate after opening.

Precautions

Keep out of reach of children.

Consult your healthcare provider if you are pregnant or breastfeeding before consuming this product.

Tamper evident customer protection: Do not use if product label has been removed or if tamper-evident cap security ring is not intact.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Recycle

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container32 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
10 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Vitamin C

Interacts with
207 drugs
180 mg per serving Form: Ascorbic Acid

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Coenzyme Q10

Interacts with
198 drugs
300 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

PQQ

30 mg per serving Form: Pyrroloquinoline Quinone Disodium Salt

Other (inactive) ingredients: Water, Purified, Soy Lecithin, Glycerin, Natural Flavors, Xantham Gum, Stevia leaf extract, Sodium Citrate, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience Drug Interactions

Want to check YOUR meds against Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
412Drugs
306 Moderate 106 Minor

Ingredients driving the most interactions

Vitamin C 207
Sodium 205
Coenzyme Q10 198

Individual Drug Interactions

The ingredients in Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor interact with 412 drugs. Click any drug to see the details.

3 of the 4 ingredients in Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor interact with drugs. Each result below shows which ingredient is responsible. Vitamin C Sodium Coenzyme Q10

Each ingredient & the kinds of drugs it affects

For each ingredient in Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor, from the product label.

Aurora NutraScience

Name
Vida Lifescience
City
Irvine
State
CA
Phone Number
1-844-321-8432
Web Address
www.VidaLifescience.com
Pharmacist Counseling Corner

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience: Common Questions

Does Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor by Aurora NutraScience interact with any medications?
Yes. Based on its ingredients, Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor has a known interaction with 412 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product actually work?
That depends on what you're using it for. Vitamin C is established for vitamin C deficiency and has solid evidence for anemia and some infections. Coenzyme Q10 is proven for CoQ10 deficiency and has reasonable evidence for heart failure, migraines, and fibromyalgia. Sodium's effectiveness is proven mainly for cystic fibrosis. For other uses, the evidence ranges from weak to absent — your doctor can tell you whether it fits your situation.
Is it safe to take this while pregnant?
Sodium and vitamin C are both Likely Safe in pregnancy at normal doses; however, vitamin C is Possibly Unsafe while breastfeeding, so if you're nursing or planning to, check with your doctor or pharmacist first. We don't have safety data on file for coenzyme Q10 or PQQ in pregnancy or breastfeeding, so discuss those with your provider for personalized advice.
What side effects should I expect?
Vitamin C can cause stomach cramps, heartburn, diarrhea, or nausea — especially at high doses. Coenzyme Q10 may cause mild nausea, diarrhea, or heartburn in less than 1% of users. Both are generally well tolerated at the doses you'd find in a supplement. The main concern with this product is sodium content and its effects on your medications and blood pressure, not the side effects of the ingredients themselves.
Can I take this if I'm on a blood thinner?
Both vitamin C and coenzyme Q10 interact with warfarin (Coumadin), a common blood thinner, potentially reducing how well it works. Sodium also raises concerns with certain medications. Do not start this product without checking your specific medication on the interaction tool on this page and talking to your pharmacist.
Will this affect my blood pressure medication?
Yes — sodium can reduce the effectiveness of blood pressure drugs, and coenzyme Q10 might have mild additive effects that lower blood pressure further. If you're on a blood pressure medication, you need to check your specific drugs with the tool on this page and discuss with your pharmacist or doctor before adding this supplement.
What is PQQ and why can't you check it?
PQQ (pyrroloquinoline quinone) is another antioxidant compound in this formula. We don't hold a monograph or interaction data for it, so we can't tell you whether it interacts with your medications. That's another reason to run your full drug list through our checker before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor label
Go deeper

The Full Monographs Behind Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

Mega-Liposomal CoQ10/PQQ+ Organic Fruit Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 129 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
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Coenzyme Q10 40 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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