MitoRestore Ingredients & Drug Interactions
What is this page for?
First and foremost: checking MitoRestore against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
MitoRestore is a dietary supplement by Microbe Formulas with 3 active ingredients. Its ingredients are commonly taken for general wellness and energy, gut health, antioxidant support.Based on those ingredients, 257 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Polyelectrole extracts. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against MitoRestore by Microbe Formulas
Ask about any prescription or over-the-counter medication and we check it for interactions with MitoRestore by Microbe Formulas — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of MitoRestore by Microbe Formulas
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
MitoRestore contains 3 active ingredients: fulvic acid compounds (supplied as polyelectrole extracts and dibasic acid) and polysaccharides. Fulvic acid is a carbon-based compound formed from the breakdown of organic matter in soil; it's the active component here.
The inactive ingredients include trace minerals and other organic acid carbon compounds in various particle sizes.
Does it work?
Couldn't assess
The evidence base for fulvic acid in MitoRestore hasn't been established in our data. All measured uses — respiratory tract infections, lead toxicity, atopic dermatitis (eczema), fatigue, and allergic rhinitis (hay fever) — are rated insufficient reliable evidence to rate.
That means we don't have enough quality research to confirm whether it works for any of these conditions.
How safe is it?
Some data gaps
Short-term oral use of fulvic acid appears generally well tolerated, though high-quality safety data in humans is limited. The most common side effects from trials are diarrhea, headache, and sore throat.
A rare serious effect called Kashin-Beck bone disease has been reported. Because there isn't enough safety information, the data advises against use during pregnancy and while breastfeeding — talk with your doctor or pharmacist about your personal situation.
Meds to double-check
Moderate interaction found
Check blood thinners (anticoagulants) and antiplatelet drugs, immunosuppressants, and thyroid hormone therapy before taking MitoRestore — fulvic acid may reduce how well they work. All three carry Moderate interaction severity.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.
MitoRestore's fulvic acid may reduce the effectiveness of blood thinners, immunosuppressants, and thyroid hormone therapy, and the evidence for its intended uses hasn't been established. If you take any of those medication types or have other prescriptions, check them against the tool on this page before you start.
It's also not recommended in pregnancy or breastfeeding without talking to your doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about MitoRestore, straight from the product label.
| Brand | Microbe Formulas |
|---|---|
| Barcode (UPC) | 788000132487 |
| Net contents | 2 Fluid Ounce(s); 59 mL |
| Market status | On market |
| Date entered into DSLD | Jan 22, 2021 |
| DSLD ID | 242205 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for MitoRestore by Microbe Formulas, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0.5 mL | -- |
| Polyelectrole extracts | 0 NP | -- |
| Polysaccharides | 0 NP | -- |
| Dibasic acid | 0 NP | -- |
Other ingredients: Ionic macro-, micro- and nano-size polyelectrolytes to include trace minerals and other organic acid carbon compounds
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Use 10 drops twice daily or as otherwise directed by a healthcare practitioner.
Precautions
Warning: Please consult your healthcare practitioner before use if you are pregnant, breastfeeding, or considering use for a child.
Warning: Please consult your healthcare practitioner before use if you are pregnant, breastfeeding, or considering use for a child.
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Statement of Identity
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Dietary Supplement
Formulation
Whole body support
Non GMO Gluten free No fillers
100% Vegan
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
MitoRestore by Microbe Formulas label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in MitoRestore by Microbe Formulas
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container118 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Polyelectrole extracts
- › Polysaccharides
- › Dibasic acid
Other (inactive) ingredients: Ionic macro-, micro- and nano-size polyelectrolytes to include trace minerals and other organic acid carbon compounds. These complete the product’s ingredient list but are not active constituents.
MitoRestore by Microbe Formulas Drug Interactions
HelloPharmacist Interaction Report
MitoRestore by Microbe Formulas interacts with medications through its fulvic acid content (listed as polyelectrole extracts and dibasic acid).
The most serious documented interaction is Moderate severity: fulvic acid may reduce how well blood thinners (anticoagulants) and antiplatelet drugs work. In vitro evidence shows fulvic acid can shorten clotting time in blood, raising the risk of clot formation.
Read the full breakdown — every affected drug type, severity by severity
Fulvic acid also carries Moderate interactions with immunosuppressant drugs — animal research suggests it stimulates immune function, which could undermine immunosuppressive therapy — and with thyroid hormone therapy. It may interfere with your ability to reach the right thyroid hormone dose by raising thyroid-stimulating hormone (TSH) levels and shifting the balance between T4 and T3.
We could not check one ingredient, polysaccharides, against our interaction database. Altogether, these interactions span 257 individual medications.
Use the medication checker on this page to search for your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against MitoRestore?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in MitoRestore interact with 257 drugs. Click any drug to see the details.
1 of the 3 ingredients in MitoRestore interact with drugs. Each result below shows which ingredient is responsible. Polyelectrole extracts
EtrasimodVelsipity
How Etrasimod interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Etrasimod interactionFamotidine, IbuprofenDuexis
How Famotidine, Ibuprofen interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Famotidine, Ibuprofen interactionFingolimodGilenya, Tascenso ODT
How Fingolimod interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Fingolimod interactionFish Oil TriglyceridesOmegaven
How Fish Oil Triglycerides interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Fish Oil Triglycerides interactionFludrocortisoneFlorinef Acetate
How Fludrocortisone interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Fludrocortisone interactionFluorouracil (iv)Fluorouracil
How Fluorouracil (iv) interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Fluorouracil (iv) interactionFlupenthixolFluanxol
How Flupenthixol interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Flupenthixol interactionFondaparinuxArixtra
How Fondaparinux interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Fondaparinux interactionFostamatinibTavalisse
How Fostamatinib interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Fostamatinib interactionGlatiramer AcetateCopaxone
How Glatiramer Acetate interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Glatiramer Acetate interactionGlofitamab-gxbmColumvi
How Glofitamab-gxbm interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Glofitamab-gxbm interactionGolimumabSimponi Aria
How Golimumab interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Golimumab interactionGuselkumabTremfya
How Guselkumab interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Guselkumab interactionHeparinHeparin
How Heparin interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Heparin interactionHuman Chorionic Gonadotropin (hcg)Pregnyl
How Human Chorionic Gonadotropin (hcg) interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidThyroid Hormone Moderate
Interaction Summary
Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Read the full Dibasic Acid + Human Chorionic Gonadotropin (hcg) interactionHyaluronidase, RituximabRituxan Hycela
How Hyaluronidase, Rituximab interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Hyaluronidase, Rituximab interactionHydrocodone, IbuprofenVicoprofen
How Hydrocodone, Ibuprofen interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Hydrocodone, Ibuprofen interactionHydrocortisoneAlkindi Sprinkle, Alphaderm, Calmurid HC, Carmol HC cream, Cortef, Dioderm +8 more
How Hydrocortisone interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Hydrocortisone interactionIbrutinibImbruvica
How Ibrutinib interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Ibrutinib interactionIbuprofenAdvil, Arthrofen, Brufen, Brufen Retard, Calodor, Calprofen +14 more
How Ibuprofen interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Ibuprofen interactionIbuprofen LysineNeoProfen
How Ibuprofen Lysine interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Ibuprofen Lysine interactionIbuprofen, AcetaminophenAdvil Dual Action
How Ibuprofen, Acetaminophen interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Ibuprofen, Acetaminophen interactionIbuprofen, HydrocodoneIbucodone
How Ibuprofen, Hydrocodone interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Ibuprofen, Hydrocodone interactionIbuprofen, OxycodoneCombunox
How Ibuprofen, Oxycodone interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Ibuprofen, Oxycodone interactionIbuprofen, PseudoephedrineDristan
How Ibuprofen, Pseudoephedrine interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Ibuprofen, Pseudoephedrine interactionIcosapent Ethyl (prescription Drug)Vascepa
How Icosapent Ethyl (prescription Drug) interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Icosapent Ethyl (prescription Drug) interactionIloprostAurlumyn, Ventavis
How Iloprost interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Iloprost interactionInebilizumab-cdonUplizna
How Inebilizumab-cdon interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Inebilizumab-cdon interactionInfliximab-abdaRenflexis
How Infliximab-abda interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Infliximab-abda interactionInfliximab-dyybInflectra
How Infliximab-dyyb interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Infliximab-dyyb interactionEach ingredient & the kinds of drugs it affects
For each ingredient in MitoRestore with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Polyelectrole extracts
Anticoagulant/Antiplatelet Drugs
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.
Immunosuppressants
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.
Thyroid Hormone
Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.
Brand information
Manufacturer and brand details for MitoRestore, from the product label.
Microbe Formulas
See all Microbe Formulas products- Name
- Microbe Formulas
- Street Address
- 3750 E. Pewter Falls St., Suite 100
- City
- Meridian
- State
- ID
- ZipCode
- 83642
- Web Address
- MicrobeFormulas.com
MitoRestore by Microbe Formulas: Common Questions
Does MitoRestore by Microbe Formulas interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does fulvic acid do in this product?
What side effects might I notice?
Can I take this while pregnant or breastfeeding?
Why does this product interact with so many drugs?
Is fulvic acid the same as humic acid?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if MitoRestore is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind MitoRestore’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
MitoRestore's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fulvic Acid 3 references
- Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
- Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
- Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC