MitoRestore Ingredients & Drug Interactions
What is this page for?
First and foremost: checking MitoRestore against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
MitoRestore is a dietary supplement by Microbe Formulas with 3 active ingredients. Its ingredients are commonly taken for general wellness and energy, gut health, antioxidant support.Based on those ingredients, 257 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Polyelectrole extracts. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against MitoRestore by Microbe Formulas
Ask about any prescription or over-the-counter medication and we check it for interactions with MitoRestore by Microbe Formulas — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of MitoRestore by Microbe Formulas
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
MitoRestore contains 3 active ingredients: fulvic acid compounds (supplied as polyelectrole extracts and dibasic acid) and polysaccharides. Fulvic acid is a carbon-based compound formed from the breakdown of organic matter in soil; it's the active component here.
The inactive ingredients include trace minerals and other organic acid carbon compounds in various particle sizes.
Does it work?
Couldn't assess
The evidence base for fulvic acid in MitoRestore hasn't been established in our data. All measured uses — respiratory tract infections, lead toxicity, atopic dermatitis (eczema), fatigue, and allergic rhinitis (hay fever) — are rated insufficient reliable evidence to rate.
That means we don't have enough quality research to confirm whether it works for any of these conditions.
How safe is it?
Some data gaps
Short-term oral use of fulvic acid appears generally well tolerated, though high-quality safety data in humans is limited. The most common side effects from trials are diarrhea, headache, and sore throat.
A rare serious effect called Kashin-Beck bone disease has been reported. Because there isn't enough safety information, the data advises against use during pregnancy and while breastfeeding — talk with your doctor or pharmacist about your personal situation.
Meds to double-check
Moderate interaction found
Check blood thinners (anticoagulants) and antiplatelet drugs, immunosuppressants, and thyroid hormone therapy before taking MitoRestore — fulvic acid may reduce how well they work. All three carry Moderate interaction severity.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.
MitoRestore's fulvic acid may reduce the effectiveness of blood thinners, immunosuppressants, and thyroid hormone therapy, and the evidence for its intended uses hasn't been established. If you take any of those medication types or have other prescriptions, check them against the tool on this page before you start.
It's also not recommended in pregnancy or breastfeeding without talking to your doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about MitoRestore, straight from the product label.
| Brand | Microbe Formulas |
|---|---|
| Barcode (UPC) | 788000132487 |
| Net contents | 2 Fluid Ounce(s); 59 mL |
| Market status | On market |
| Date entered into DSLD | Jan 22, 2021 |
| DSLD ID | 242205 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for MitoRestore by Microbe Formulas, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0.5 mL | -- |
| Polyelectrole extracts | 0 NP | -- |
| Polysaccharides | 0 NP | -- |
| Dibasic acid | 0 NP | -- |
Other ingredients: Ionic macro-, micro- and nano-size polyelectrolytes to include trace minerals and other organic acid carbon compounds
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Use 10 drops twice daily or as otherwise directed by a healthcare practitioner.
Precautions
Warning: Please consult your healthcare practitioner before use if you are pregnant, breastfeeding, or considering use for a child.
Warning: Please consult your healthcare practitioner before use if you are pregnant, breastfeeding, or considering use for a child.
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Statement of Identity
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Dietary Supplement
Formulation
Whole body support
Non GMO Gluten free No fillers
100% Vegan
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
MitoRestore by Microbe Formulas label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in MitoRestore by Microbe Formulas
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container118 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Polyelectrole extracts
- › Polysaccharides
- › Dibasic acid
Other (inactive) ingredients: Ionic macro-, micro- and nano-size polyelectrolytes to include trace minerals and other organic acid carbon compounds. These complete the product’s ingredient list but are not active constituents.
MitoRestore by Microbe Formulas Drug Interactions
HelloPharmacist Interaction Report
MitoRestore by Microbe Formulas interacts with medications through its fulvic acid content (listed as polyelectrole extracts and dibasic acid).
The most serious documented interaction is Moderate severity: fulvic acid may reduce how well blood thinners (anticoagulants) and antiplatelet drugs work. In vitro evidence shows fulvic acid can shorten clotting time in blood, raising the risk of clot formation.
Read the full breakdown — every affected drug type, severity by severity
Fulvic acid also carries Moderate interactions with immunosuppressant drugs — animal research suggests it stimulates immune function, which could undermine immunosuppressive therapy — and with thyroid hormone therapy. It may interfere with your ability to reach the right thyroid hormone dose by raising thyroid-stimulating hormone (TSH) levels and shifting the balance between T4 and T3.
We could not check one ingredient, polysaccharides, against our interaction database. Altogether, these interactions span 257 individual medications.
Use the medication checker on this page to search for your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against MitoRestore?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in MitoRestore interact with 257 drugs. Click any drug to see the details.
1 of the 3 ingredients in MitoRestore interact with drugs. Each result below shows which ingredient is responsible. Polyelectrole extracts
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Alemtuzumab interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Antithrombin Iii interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidImmunosuppressants Moderate
Interaction Summary
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Dibasic Acid + Antithymocyte Globulin interactionApixabanEliquis
How Apixaban interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with MitoRestore — through 1 ingredient. Tap an ingredient for the detail:
Dibasic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Dibasic Acid + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in MitoRestore with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Polyelectrole extracts
Anticoagulant/Antiplatelet Drugs
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.
Immunosuppressants
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.
Thyroid Hormone
Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.
Brand information
Manufacturer and brand details for MitoRestore, from the product label.
Microbe Formulas
See all Microbe Formulas products- Name
- Microbe Formulas
- Street Address
- 3750 E. Pewter Falls St., Suite 100
- City
- Meridian
- State
- ID
- ZipCode
- 83642
- Web Address
- MicrobeFormulas.com
MitoRestore by Microbe Formulas: Common Questions
Does MitoRestore by Microbe Formulas interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does fulvic acid do in this product?
What side effects might I notice?
Can I take this while pregnant or breastfeeding?
Why does this product interact with so many drugs?
Is fulvic acid the same as humic acid?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if MitoRestore is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind MitoRestore’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
MitoRestore's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fulvic Acid 3 references
- Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
- Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
- Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC