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Dietary supplement

Modified Citrus Pectin Ingredients & Drug Interactions

by Douglas Laboratories

Modified Citrus Pectin label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Modified Citrus Pectin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Modified Citrus Pectin is a dietary supplement by Douglas Laboratories with 1 active ingredient. Its ingredients are commonly taken for diarrhea relief, constipation and digestive health, cholesterol support.Based on those ingredients, 23 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are PectaSol(R). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Modified Citrus Pectin by Douglas Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Modified Citrus Pectin by Douglas Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Modified Citrus Pectin by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: PectaSol®, a form of modified citrus pectin. Pectin is a fiber derived from citrus fruit that's used as a dietary supplement.

The capsules also contain cellulose, gelatin, and vegetable stearate as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Pectin's overall clinical evidence instead.

Moderate

Some clinical evidence supports Pectin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Hypercholesterolemia — rated "Possibly Effective" (Natural Medicines).

Modified citrus pectin is possibly effective for high cholesterol (hypercholesterolemia) based on current evidence. For blood sugar control in prediabetes and for protecting against radiation exposure, there isn't enough reliable evidence in our data to say whether it works.

The evidence, ingredient by ingredient Pectin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pectin from food and typical supplement doses is generally well tolerated. The most common side effects are mild — diarrhea, gas, loose stools, and mild stomach cramps.

Rarely, allergic reactions including severe reactions (anaphylaxis) can occur in people sensitive to pectin; occupational exposure to pectin dust can also trigger asthma. For pregnancy and breastfeeding, the safety data shows concentrated supplements haven't been well studied, so talk with your doctor or pharmacist before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Pectin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pectin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 23 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check if you're on digoxin (a heart medication), lovastatin (a cholesterol drug), or tetracycline antibiotics — pectin may reduce how much of these your body absorbs and decrease their effectiveness. Use the medication checker on this page to confirm your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Modified citrus pectin may help with high cholesterol, but it can reduce how your body absorbs certain heart, cholesterol, and antibiotic medications. If you take digoxin, lovastatin, or tetracycline antibiotics, check with your doctor or pharmacist before starting.

Most people tolerate it well, though digestive side effects and rare allergies are possible.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Modified Citrus Pectin, straight from the product label.

Brand Douglas Laboratories
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2012
DSLD ID 10077
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Modified Citrus Pectin by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
90
IngredientAmount% DV
PectaSol(R)800 mg--

Other ingredients: Cellulose, Gelatin, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 3-18 capsules per day. Take 1-6 capsules with water, juice or other liquid drink, three times per day, or as directed by your healthcare professional.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

General Statements

A Natural Product Made from Citrus Fruit: Variations in color, texture or flavor may occur.

General

Formula #82046

Brand IP Statement(s)

Ordinary pectin is a complex carbohydrate molecule found in almost all plants, which is not absorbed due to its long molecular chain. PectaSol(R)'s exclusive formulation and processing result in a shorter molecular chain that is readily absorbed, thus allowing the body to utilize the essential polysaccharide compounds.

PectaSol(R) is a registered trademark of EcoNugenics(R), Inc. PectaSol(R) is protected under US Patent No. #6,274,566, #6,462,029 and #7,026,302.

PectaSol(R) is manufactured to GMP/ISO-9001 standards. Meets requirements of GRAS, CAS, WHO, EC, FCC.

PectaSol(R) Modified Citrus Pectin is a complex polysaccharide rich in galactosyl residues.

PectaSol(R) was developed by a research and development team working with the world's leading pectin scientists.

Formulation

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Modified Citrus Pectin by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Modified Citrus Pectin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Modified Citrus Pectin by Douglas Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

PectaSol(R)

Interacts with
23 drugs
800 mg per serving

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...

PectaSol(R) monograph & interactions

Other (inactive) ingredients: Cellulose, Gelatin, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Modified Citrus Pectin by Douglas Laboratories Drug Interactions

Want to check YOUR meds against Modified Citrus Pectin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
23Drugs
23 Moderate

Ingredients driving the most interactions

PectaSol(R) 23

Individual Drug Interactions

The ingredients in Modified Citrus Pectin interact with 23 drugs. Click any drug to see the details.

1 of the 1 ingredient in Modified Citrus Pectin interact with drugs. Each result below shows which ingredient is responsible. PectaSol(R)

Each ingredient & the kinds of drugs it affects

For each ingredient in Modified Citrus Pectin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

PectaSol(R)3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
PectaSol(R) full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Modified Citrus Pectin, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Modified Citrus Pectin by Douglas Laboratories: Common Questions

Does Modified Citrus Pectin by Douglas Laboratories interact with any medications?
Yes. Based on its ingredients, Modified Citrus Pectin has a known interaction with 23 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Modified Citrus Pectin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
The safety data hasn't thoroughly studied concentrated pectin supplements in pregnancy. Talk with your doctor or pharmacist before taking it — they can weigh the pros and cons for your situation.
What are the side effects?
Most people experience mild digestive effects like diarrhea, gas, loose stools, or mild cramps. Rarely, sensitive individuals may have an allergic reaction; if you have a history of food allergies or oral allergy syndrome, mention that to your pharmacist.
Does this actually work for cholesterol?
Yes, modified citrus pectin is possibly effective for high cholesterol based on available evidence. For blood sugar problems or radiation protection, we don't have enough reliable data to say whether it works.
Why might it interfere with my medications?
Pectin is a fiber that can bind to certain medications in your digestive tract and reduce how much of them your body absorbs — that's especially true for digoxin, lovastatin, and tetracycline antibiotics, which may then work less well.
Is it safe for breastfeeding?
Dietary amounts of pectin are fine, but the safety of concentrated supplements while breastfeeding hasn't been well studied. Check with your doctor or pharmacist for personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Modified Citrus Pectin is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Modified Citrus Pectin label
Go deeper

The Full Monographs Behind Modified Citrus Pectin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pectin

Interacts with 23 drugs

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...

Read the full Pectin monograph →
Sources

Sources & How We Checked

Modified Citrus Pectin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pectin 11 references
  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed

See these in context on the Pectin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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