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Dietary supplement

Moringa Ingredients & Drug Interactions

by Ayur Earth

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Moringa is a dietary supplement by Ayur Earth with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement, blood sugar support, cholesterol support.Based on those ingredients, 869 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shigru powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Moringa by Ayur Earth

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: shigru powder, also called moringa leaf powder. Moringa is a plant whose leaves have been used in traditional medicine and as a food supplement.

The tablets also include inactive ingredients — xanthan gum, maize starch, silicon dioxide, HPMC (a capsule material), and magnesium stearate — which are fillers and binders that hold the tablet together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support healthy bodily function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for moringa's effectiveness against the conditions it's marketed for — iron deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, and high cholesterol — is not established in our data. Each of these carries a rating of insufficient reliable evidence, meaning the research to date hasn't been strong or consistent enough to draw firm conclusions.

If you're considering moringa for one of these uses, talk with your doctor or pharmacist about whether the current research supports it for your specific situation.

The evidence, ingredient by ingredient Moringa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Moringa leaf powder appears generally well tolerated when used as food, though high-quality safety data are limited. The most common side effect reported is transient diarrhea — in one trial, about a quarter of people taking 8 grams daily experienced it.

Rare but serious allergic reactions, including anaphylaxis, have been reported. Stevens-Johnson syndrome (a severe skin and mucous membrane reaction) has also been linked to moringa leaf consumption in at least one case report.

Do not use medicinal amounts of moringa root or bark, as they may stimulate the uterus and safety data are lacking. If you are breastfeeding and interested in moringa (traditionally used to boost milk supply), safety has not been well studied, so check with your doctor or pharmacist before use.

Side effects, ingredient by ingredient Moringa

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Moringa.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 870 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this moringa product, double-check with your doctor or pharmacist if you take levothyroxine (Synthroid) or any thyroid medication; moringa may weaken its effect. Also check if you take medications metabolized by your liver's CYP3A4 enzyme (a very large group — your pharmacist can tell you) or by a kidney protein called P-glycoprotein, antidiabetes drugs, or any CYP1A2 substrates.

No interactions are documented with any other medication types in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Moringa may be an option if you're interested in a plant-based supplement, but it carries Moderate interaction risks with thyroid, liver, and kidney medications — and the effect is sometimes unpredictable. If you take levothyroxine, any medications metabolized by CYP3A4 or P-glycoprotein, or diabetes drugs, you'll need to check with your own doctor or pharmacist before starting.

The evidence for its marketed uses isn't established yet, so it's not a proven remedy for any specific condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Moringa, straight from the product label.

Brand Ayur Earth
Barcode (UPC) 689128589835
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 248045
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Moringa by Ayur Earth, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
689128589835
IngredientAmount% DV
Shigru powder500 mg--

Other ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, HPMC, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Ayurvedic herbs Pure Natural Effective

V Vegetarian

Non GMO

May support healthy bodily function. Accordingly to traditional texts Moringa is considered to have more than 90 beneficial compounds & antioxidants properties.

Product of India

Free of dairy & soy

Gluten free

Formula

Moringa oleifera

Seals/Symbols

V Vegetarian

ISO Certified Company GMP Good Manufacturing Practice FDA Registered Facility 12251469598

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Direction for Use: As a dietary supplement take 1 tablet twice daily, preferably after meals. For better results it should be taken with warm water

Precautions

Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.

Keep out of reach of children.

Do not use if inner seal is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Batch No. : AT621 Expiry DT. : 03/2020 Neutral Code: MH/PD/AYU/002/10

Storage

Store in a cool dry place away from direct sunlight.

See for yourself

Moringa by Ayur Earth label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Moringa by Ayur Earth

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Shigru powder

Interacts with
869 drugs
500 mg per serving

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....

Shigru powder monograph & interactions

Other (inactive) ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, HPMC, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Moringa by Ayur Earth Drug Interactions

Want to check YOUR meds against Moringa?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
869Drugs
717 Moderate 152 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Moringa with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Shigru powder6 drug types · 869 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Possible Evidence D
Levothyroxine (Synthroid, Others)

Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Nevirapine (Viramune)

Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Moringa, from the product label.

Ayur Earth

See all Ayur Earth products
Name
U4LIFE, LLC. d.b.a. Ayur Earth
Street Address
PO Box #5
City
Edgewater
State
NJ
ZipCode
07020
Web Address
www.ayurearth.com
Pharmacist Counseling Corner

Moringa by Ayur Earth: Common Questions

Does Moringa by Ayur Earth interact with any medications?
Yes. Based on its ingredients, Moringa has a known interaction with 869 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Moringa contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take moringa if I'm pregnant?
Moringa leaf is rated possibly safe in pregnancy, but the safety data aren't robust. Do not use medicinal amounts of the root or bark, as they may stimulate the uterus and safety information is lacking. Talk with your doctor or pharmacist about whether moringa is right for your situation.
Can I take moringa while breastfeeding?
Moringa is rated possibly safe during breastfeeding and has been traditionally used to boost milk supply, but safety hasn't been well studied. Check with your doctor or pharmacist before starting, especially if you're relying on it for a specific purpose.
What's the most common side effect?
Diarrhea is the main side effect — and it's usually temporary. In one trial, about 25% of people taking 8 grams daily experienced it. Allergic reactions and Stevens-Johnson syndrome have been reported but are rare.
Does moringa actually work for anemia, diabetes, or asthma?
The evidence we have isn't strong enough yet to say. All of these uses are rated insufficient reliable evidence, meaning research hasn't been consistent or thorough enough to confirm moringa helps. Your doctor can tell you whether it's worth trying for your specific condition.
Is moringa safe to take long-term?
Moringa leaf appears well tolerated as food, but high-quality long-term safety data are limited. If you're taking it daily alongside medications, the interaction risks with liver and kidney drugs are the bigger concern — check those with your pharmacist.
What exactly is shigru powder?
Shigru is another name for moringa leaf powder — the dried, ground leaves of the moringa plant. It's used in traditional medicine and is sometimes eaten as a food or supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Moringa is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Moringa label
Sources

Sources & How We Checked

Moringa's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Moringa 23 references
  1. Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
  2. Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000;41:319-23. PubMed
  3. Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
  4. Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
  5. Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
  6. Monera TG, Wolfe AR, Maponga CC, et al. Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2008;2:379-83.
  7. Estrella M, Mantaring J, David G, Taup M. A double blind, randomised controlled trial on the use of malunggay (Moringa oleifera) for augmentation of the volume of breastmilk among non-nursing mothers of preterm infants. Philipp J Pediatr 2000;49:3-6.
  8. Morton, J. F. The Horseradish Tree, Moringa Pterygosperma (Moringaceae) - a boon to arid lands? Economic Botany 1991;45:318-333. DOI
  9. Espinosa-Kuo CL. A Randomized Controlled Trial on the Use of Malunggay (Moringa oleifera) for Augmentation of the Volume of Breastmilk Among Mothers of Term Infants. Filipino Family Physician. 2005;43(1):26-33.
  10. King JS, Raguindin PFN, Dans LF. Moringa oleifera (Malunggay) as a Galactagogue for Breastfeeding Mothers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Philipp J Pediatr 2013;61(2):34-42.
  11. Singh D, Choudhury S, Singh TU, Garg SK. Pharmacodynamics of uterotonic effect of Moringa oleifera flowers extract. J Vet Pharmcol Toxicol 2008;7(1-2):12-15.
  12. William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
  13. Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017;14:12. doi: 10.1186/s1 PubMed
  14. Witharana EWRA, Wijetunga WMGASTB, Wijesinghe SKJ. Stevens - Johnson syndrome (SJS) following murunga leaf (Moringa oleifera) consumption. Ceylon Med J 2018;63(4):188-9.
  15. Nur R, Demak IPK, Radhiah S, Rusydi M, Mantao E, Larasati RD. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women. Enferm Clin. 2020;30 Suppl 4:79-82. DOI
  16. Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M
  17. Sumiaty, Tahir A, Burhanuddin B, Nurhaedar J, Veni H. The effect of moringa leaves on pregnancy on growth and morbidity of 6-11 month. Enferm Clin. 2020;30 Suppl 4:104-108. DOI
  18. Ulmy MN, Tahir A, Arsunan AA, Burhanuddin B, Veni H. Effect of moringa leaves during pregnancy on growth and morbidity in 0-5 months. Enferm Clin. 2020;30 Suppl 4:61-65. DOI
  19. Amaeze O, Marques ES, Wei W, et al. Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction. Curr Drug Metab. 2021;22(14):1103-1113. PubMed
  20. Ebhohon E, Miller D. Moringa Oleifera leaf extract induced pulmonary embolism-a case report. Int J Emerg Med 2022;15(1):16. PubMed
  21. Basri H, Hadju V, Zulkifli A, Syam A, Indriasari R. Effect of Moringa oleifera supplementation during pregnancy on the prevention of stunted growth in children between the ages of 36 to 42 months. J Public Health Res 2021;10(2):2207.
  22. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  23. Amsler E, Mahevas T, Soria A, Barbaud A. Fixed food eruption to Moringa oleifera. Contact Dermatitis 2023;89(4):301-302.

See these in context on the Moringa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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