Moringa Ingredients & Drug Interactions
by Ayur Earth
What is this page for?
First and foremost: checking Moringa against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Moringa is a dietary supplement by Ayur Earth with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement, blood sugar support, cholesterol support.Based on those ingredients, 869 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shigru powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Moringa by Ayur Earth
Ask about any prescription or over-the-counter medication and we check it for interactions with Moringa by Ayur Earth — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Moringa by Ayur Earth
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: shigru powder, also called moringa leaf powder. Moringa is a plant whose leaves have been used in traditional medicine and as a food supplement.
The tablets also include inactive ingredients — xanthan gum, maize starch, silicon dioxide, HPMC (a capsule material), and magnesium stearate — which are fillers and binders that hold the tablet together.
Does it work?
Couldn't assess
The evidence for moringa's effectiveness against the conditions it's marketed for — iron deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, and high cholesterol — is not established in our data. Each of these carries a rating of insufficient reliable evidence, meaning the research to date hasn't been strong or consistent enough to draw firm conclusions.
If you're considering moringa for one of these uses, talk with your doctor or pharmacist about whether the current research supports it for your specific situation.
How safe is it?
Well-documented data
Moringa leaf powder appears generally well tolerated when used as food, though high-quality safety data are limited. The most common side effect reported is transient diarrhea — in one trial, about a quarter of people taking 8 grams daily experienced it.
Rare but serious allergic reactions, including anaphylaxis, have been reported. Stevens-Johnson syndrome (a severe skin and mucous membrane reaction) has also been linked to moringa leaf consumption in at least one case report.
Do not use medicinal amounts of moringa root or bark, as they may stimulate the uterus and safety data are lacking. If you are breastfeeding and interested in moringa (traditionally used to boost milk supply), safety has not been well studied, so check with your doctor or pharmacist before use.
Meds to double-check
Moderate interaction found
Before taking this moringa product, double-check with your doctor or pharmacist if you take levothyroxine (Synthroid) or any thyroid medication; moringa may weaken its effect. Also check if you take medications metabolized by your liver's CYP3A4 enzyme (a very large group — your pharmacist can tell you) or by a kidney protein called P-glycoprotein, antidiabetes drugs, or any CYP1A2 substrates.
No interactions are documented with any other medication types in our data.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Moringa may be an option if you're interested in a plant-based supplement, but it carries Moderate interaction risks with thyroid, liver, and kidney medications — and the effect is sometimes unpredictable. If you take levothyroxine, any medications metabolized by CYP3A4 or P-glycoprotein, or diabetes drugs, you'll need to check with your own doctor or pharmacist before starting.
The evidence for its marketed uses isn't established yet, so it's not a proven remedy for any specific condition.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Moringa, straight from the product label.
| Brand | Ayur Earth |
|---|---|
| Barcode (UPC) | 689128589835 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 248045 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Moringa by Ayur Earth, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Shigru powder | 500 mg | -- |
Other ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, HPMC, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Ayurvedic herbs Pure Natural Effective
V Vegetarian
Non GMO
May support healthy bodily function. Accordingly to traditional texts Moringa is considered to have more than 90 beneficial compounds & antioxidants properties.
Product of India
Free of dairy & soy
Gluten free
Formula
Moringa oleifera
Seals/Symbols
V Vegetarian
ISO Certified Company GMP Good Manufacturing Practice FDA Registered Facility 12251469598
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Direction for Use: As a dietary supplement take 1 tablet twice daily, preferably after meals. For better results it should be taken with warm water
Precautions
Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.
Keep out of reach of children.
Do not use if inner seal is broken or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Batch No. : AT621 Expiry DT. : 03/2020 Neutral Code: MH/PD/AYU/002/10
Storage
Store in a cool dry place away from direct sunlight.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Moringa by Ayur Earth label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Moringa by Ayur Earth
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Shigru powder
Interacts with869 drugs
Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....
Shigru powder monograph & interactionsOther (inactive) ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, HPMC, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Moringa by Ayur Earth Drug Interactions
HelloPharmacist Interaction Report
Moringa by Ayur Earth contains shigru powder (moringa leaf), which does interact with several medication types.
The most serious documented interaction is Moderate severity with levothyroxine (Synthroid and others), a thyroid hormone — moringa may reduce how well your body converts the inactive form to the active form your cells need, potentially weakening the drug's effect.
Read the full breakdown — every affected drug type, severity by severity
Moringa also has Moderate interactions with two other drug categories: CYP3A4 substrates (a large group of medications whose levels your liver controls — moringa's effect here is unpredictable, as research shows it might increase OR decrease them) and P-glycoprotein substrates (a group of drugs your kidneys handle — moringa may raise their levels and effects). Minor interactions are documented with antidiabetes drugs and CYP1A2 substrates; moringa might lower blood sugar additively (though human evidence is mixed) or reduce how well the second group of drugs work.
One medication, nevirapine (an HIV drug), was studied directly with moringa in patients, and no change in drug levels was observed — so that's the one case where real-world evidence reassures us.
Altogether, these interactions span 870 individual medications. Because moringa's effects on liver and kidney drug handling are unpredictable, you'll want to check your exact medications with the tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Moringa?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Moringa interact with 869 drugs. Click any drug to see the details.
1 of the 1 ingredient in Moringa interact with drugs. Each result below shows which ingredient is responsible. Shigru powder
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acalabrutinib interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Shigru Powder + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Moringa — through 1 ingredient. Tap an ingredient for the detail:
Shigru PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Shigru Powder + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Moringa with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Shigru powder
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.
Levothyroxine (Synthroid, Others)
Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.
P-Glycoprotein Substrates
Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.
Antidiabetes Drugs
Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.
Nevirapine (Viramune)
Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.
Brand information
Manufacturer and brand details for Moringa, from the product label.
Ayur Earth
See all Ayur Earth products- Name
- U4LIFE, LLC. d.b.a. Ayur Earth
- Street Address
- PO Box #5
- City
- Edgewater
- State
- NJ
- ZipCode
- 07020
- Web Address
- www.ayurearth.com
Moringa by Ayur Earth: Common Questions
Does Moringa by Ayur Earth interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take moringa if I'm pregnant?
Can I take moringa while breastfeeding?
What's the most common side effect?
Does moringa actually work for anemia, diabetes, or asthma?
Is moringa safe to take long-term?
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The Full Monographs Behind Moringa’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Moringa's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Moringa 23 references
- Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
- Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000;41:319-23. PubMed
- Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
- Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
- Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
- Monera TG, Wolfe AR, Maponga CC, et al. Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2008;2:379-83.
- Estrella M, Mantaring J, David G, Taup M. A double blind, randomised controlled trial on the use of malunggay (Moringa oleifera) for augmentation of the volume of breastmilk among non-nursing mothers of preterm infants. Philipp J Pediatr 2000;49:3-6.
- Morton, J. F. The Horseradish Tree, Moringa Pterygosperma (Moringaceae) - a boon to arid lands? Economic Botany 1991;45:318-333. DOI
- Espinosa-Kuo CL. A Randomized Controlled Trial on the Use of Malunggay (Moringa oleifera) for Augmentation of the Volume of Breastmilk Among Mothers of Term Infants. Filipino Family Physician. 2005;43(1):26-33.
- King JS, Raguindin PFN, Dans LF. Moringa oleifera (Malunggay) as a Galactagogue for Breastfeeding Mothers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Philipp J Pediatr 2013;61(2):34-42.
- Singh D, Choudhury S, Singh TU, Garg SK. Pharmacodynamics of uterotonic effect of Moringa oleifera flowers extract. J Vet Pharmcol Toxicol 2008;7(1-2):12-15.
- William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
- Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017;14:12. doi: 10.1186/s1 PubMed
- Witharana EWRA, Wijetunga WMGASTB, Wijesinghe SKJ. Stevens - Johnson syndrome (SJS) following murunga leaf (Moringa oleifera) consumption. Ceylon Med J 2018;63(4):188-9.
- Nur R, Demak IPK, Radhiah S, Rusydi M, Mantao E, Larasati RD. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women. Enferm Clin. 2020;30 Suppl 4:79-82. DOI
- Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M
- Sumiaty, Tahir A, Burhanuddin B, Nurhaedar J, Veni H. The effect of moringa leaves on pregnancy on growth and morbidity of 6-11 month. Enferm Clin. 2020;30 Suppl 4:104-108. DOI
- Ulmy MN, Tahir A, Arsunan AA, Burhanuddin B, Veni H. Effect of moringa leaves during pregnancy on growth and morbidity in 0-5 months. Enferm Clin. 2020;30 Suppl 4:61-65. DOI
- Amaeze O, Marques ES, Wei W, et al. Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction. Curr Drug Metab. 2021;22(14):1103-1113. PubMed
- Ebhohon E, Miller D. Moringa Oleifera leaf extract induced pulmonary embolism-a case report. Int J Emerg Med 2022;15(1):16. PubMed
- Basri H, Hadju V, Zulkifli A, Syam A, Indriasari R. Effect of Moringa oleifera supplementation during pregnancy on the prevention of stunted growth in children between the ages of 36 to 42 months. J Public Health Res 2021;10(2):2207.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Amsler E, Mahevas T, Soria A, Barbaud A. Fixed food eruption to Moringa oleifera. Contact Dermatitis 2023;89(4):301-302.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC