Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Myo & D-Chiro Inositol + Folate Ingredients & Drug Interactions

by ForestLeaf

Myo & D-Chiro Inositol + Folate label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Myo & D-Chiro Inositol + Folate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Myo & D-Chiro Inositol + Folate is a dietary supplement by ForestLeaf with 3 active ingredients. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Chiro Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Myo & D-Chiro Inositol + Folate by ForestLeaf

Ask about any prescription or over-the-counter medication and we check it for interactions with Myo & D-Chiro Inositol + Folate by ForestLeaf — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Myo & D-Chiro Inositol + Folate by ForestLeaf

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 3 active ingredients: two forms of inositol — D-Chiro Inositol and Myo-Inositol — and Folate. The inositols are naturally occurring compounds that play a role in how your body manages blood sugar and has been studied in several reproductive and metabolic conditions.

Folate is a B vitamin. The capsule also contains inactive ingredients — Hypromellose, Magnesium Stearate, Silicon Dioxide, and Microcrystalline Cellulose — which are standard binders and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: female hormone balance and menstrual health.
  • We looked for evidence on: Polycystic ovary syndrome (PCOS), Infertility, Anxiety, Depression, Panic disorder, Metabolic syndrome — and 4 related terms.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Effective" for Metabolic syndrome.
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety, Depression.

The inositols in this product are rated possibly effective for polycystic ovary syndrome (PCOS), metabolic syndrome, and preterm labor. For anxiety, diabetic nerve pain, and depression, the evidence suggests they are possibly ineffective.

The strength of evidence varies, so talk to your doctor about whether this product fits your particular situation. We don't have effectiveness data on file for Folate in this product.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both forms of inositol are generally well tolerated at common doses. The most common side effects from taking it by mouth are mild digestive ones — diarrhea, gas, and nausea.

Some research combined inositol with omega-3s in children and reported cold and allergy symptoms in a small number of participants. The inositols have been used in pregnancy in some studies, but safety is not fully established, so use only under medical supervision if you're pregnant or planning pregnancy.

There isn't enough reliable information to know how safe they are when breastfeeding — check with your doctor.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (like metformin, glyburide, or insulin), check with your pharmacist first — the inositol in this product can lower your blood sugar further and may increase your risk of hypoglycemia. We were unable to check Folate for interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have PCOS, metabolic syndrome, or are at risk of preterm labor, this product may be worth talking about with your doctor. If you take diabetes medication, you'll need to watch your blood sugar closely — the inositol here actively lowers it.

Stop if you get diarrhea, gas, or nausea, and bring your medications to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Myo & D-Chiro Inositol + Folate, straight from the product label.

Brand ForestLeaf
Net contents 120 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 323040
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Myo & D-Chiro Inositol + Folate by ForestLeaf, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Folate400 mcg DFE100%
D-Chiro Inositol50 mg--
Myo-Inositol2000 mg--

Other ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Myo & D-Chiro Inositol supports female hormone balance, physical functions, memory, focus, energy and clarity.

Women's Health

Myo & D-Chiro Inositol + Folate Effective 40:1 Ratio

Formulation

Hormonal balance Physical functions Healthy menstrual cycle

GMP Compliant Lab Verified

Vegetarian friendly

Non GMO Dairy, gluten. egg & nut free

Tested for absorption Female hormone support

FDA Disclaimer Statement

Theses statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in USA with Globally sourced ingredients Vegetarian friendly

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, adults take 4 capsules daily, preferably with a meal, or as directed by your healthcare professional. For those with a sensitive stomach take 2 capsules twice daily.

Precautions

Caution: Keep out of reach of children.

If you are pregnant, nursing, or taking any prescription medicine, consult your physician before taking this product.

Storage

Store in a cool, dry place.

General Statements

Instagram Facebook T: 929.810.5089

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Myo & D-Chiro Inositol + Folate by ForestLeaf label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Myo & D-Chiro Inositol + Folate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Myo & D-Chiro Inositol + Folate by ForestLeaf

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Folate

400 mcg DFE per serving Form: L-Methylfolate Calcium Salt

D-Chiro Inositol

Interacts with
86 drugs
50 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

D-Chiro Inositol monograph & interactions

Myo-Inositol

Interacts with
86 drugs
2000 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Myo-Inositol monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Myo & D-Chiro Inositol + Folate by ForestLeaf Drug Interactions

Want to check YOUR meds against Myo & D-Chiro Inositol + Folate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Chiro Inositol 86

Individual Drug Interactions

The ingredients in Myo & D-Chiro Inositol + Folate interact with 86 drugs. Click any drug to see the details.

1 of the 3 ingredients in Myo & D-Chiro Inositol + Folate interact with drugs. Each result below shows which ingredient is responsible. D-Chiro Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Myo & D-Chiro Inositol + Folate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Chiro Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
D-Chiro Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Myo & D-Chiro Inositol + Folate, from the product label.

ForestLeaf

See all ForestLeaf products
Name
ForestLeaf
City
Brooklyn
State
NY
ZipCode
11219
Phone Number
929.810.5089
Web Address
www.ForestLeaf.com
Pharmacist Counseling Corner

Myo & D-Chiro Inositol + Folate by ForestLeaf: Common Questions

Does Myo & D-Chiro Inositol + Folate by ForestLeaf interact with any medications?
Yes. Based on its ingredients, Myo & D-Chiro Inositol + Folate has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Myo & D-Chiro Inositol + Folate contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or trying to become pregnant?
The inositols in this product have been studied in pregnancy, but safety isn't fully established. If you're pregnant or planning pregnancy, use this only under your doctor's direct supervision. There's not enough data on breastfeeding either — talk with your doctor or pharmacist for personalized advice.
What side effects should I watch for?
The most common ones are mild and digestive — diarrhea, gas, and nausea. These are usually mild at standard doses. If you're taking it with omega-3 supplements, a small number of children in trials reported cold and allergy-like symptoms.
Does this actually work for PCOS?
The inositols here are rated possibly effective for PCOS based on available research. It's not a guarantee, but there's enough evidence to suggest it may help. Your doctor can tell you if it's a fit for your situation.
What does each ingredient do?
The two forms of inositol — D-Chiro Inositol and Myo-Inositol — are compounds your body uses to regulate blood sugar and have been studied for PCOS and metabolic health. Folate is a B vitamin. Together they're meant to support metabolic and reproductive function.
Is this safe if I don't have diabetes?
It's generally well tolerated at common doses for people without diabetes. The main concern is digestive side effects like diarrhea, gas, or nausea. If you have any health conditions or take medications, check with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Myo & D-Chiro Inositol + Folate is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Myo & D-Chiro Inositol + Folate label
Go deeper

The Full Monographs Behind Myo & D-Chiro Inositol + Folate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Myo & D-Chiro Inositol + Folate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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