Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Natural Tropical Papaya Ingredients & Drug Interactions

by Country Life

Natural Tropical Papaya label
See full label image
Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Natural Tropical Papaya against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Natural Tropical Papaya is a dietary supplement by Country Life with 5 active ingredients. Its ingredients are commonly taken for digestive support for protein digestion, wound cleaning (debridement of dead tissue), sore throat and inflammation.Based on those ingredients, 92 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Papaya, Papain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Natural Tropical Papaya by Country Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Natural Tropical Papaya by Country Life — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Natural Tropical Papaya by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 4 active ingredients: papain (an enzyme from papaya that breaks down proteins), protease (another protein-digesting enzyme), alpha-amylase (a starch-digesting enzyme), and papaya fruit itself. They're combined in a form containing inactive ingredients like fructose, mannitol, starch, silica, and cellulose that act as fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: digestive enzymes support for nutrient absorption.
  • We looked for evidence on: Intestinal parasite infection, Indigestion, Constipation, Bloating.
  • The closest evidence on file: Papain is rated "Insufficient Reliable Evidence To Rate" for Intestinal parasite infection (Natural Medicines).
  • Also on file: Papaya is rated "Insufficient Reliable Evidence To Rate" for Intestinal parasite infection.

The evidence for papain isn't established in the data we hold—it's rated as having insufficient reliable evidence for cancer, dental cavities, radiation skin damage, exercise muscle soreness, shingles, and intestinal parasites. Papaya shows the same pattern: insufficient reliable evidence for aging skin, hair loss, various cancers, and diabetes.

We have no effectiveness ratings on file for protease or alpha-amylase.

The evidence, ingredient by ingredient Papain Proteolytic Enzymes (proteases) Papaya

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Papain is generally tolerated as food but can irritate the digestive tract and trigger allergic reactions (itchy eyes, runny nose, sneezing, abdominal cramps, or diarrhea) in sensitive people. High doses may be unsafe and in rare cases have caused severe inflammation or perforation of the esophagus.

Unripe papaya and concentrated papain are best avoided in pregnancy due to safety concerns; there isn't enough data to know if supplemental papain is safe while breastfeeding, so talk with your doctor or pharmacist. Protease is generally well tolerated but may cause digestive upset or allergic reactions.

Safety hasn't been established in pregnancy, so it's best avoided unless prescribed; there's little safety data during breastfeeding. Papaya fruit itself is well tolerated in food amounts; ripe fruit is likely safe in moderation, but concentrated supplements and unripe papaya are less well studied and should be avoided, especially in pregnancy.

Side effects, ingredient by ingredient Papain Proteolytic Enzymes (proteases) Papaya

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Papain, Papaya.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 92 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before using if you take warfarin (Coumadin) or any blood thinner—papain may boost its effects. Also double-check if you're on diabetes medications, amiodarone (Cordarone) for heart rhythm, or levothyroxine (Synthroid) for thyroid function, as papaya may affect how they work.

Use the medication search on this page to confirm your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines fruit enzymes with unknown effectiveness for most claimed uses. If you take warfarin, any diabetes medication, amiodarone, or levothyroxine, check your exact medications with the tool on this page before starting.

Allergic reactions and digestive upset are possible, especially in sensitive individuals. Talk with your doctor or pharmacist before you take it, particularly if you're pregnant, breastfeeding, or on prescription drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natural Tropical Papaya, straight from the product label.

Brand Country Life
Barcode (UPC) 015794053835
Net contents 200 Chewable Wafer(s)
Market status On market
Date entered into DSLD Sep 22, 2016
DSLD ID 64975
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natural Tropical Papaya by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Wafer(s)
Maximum serving Sizes:
4 Wafer(s)
Servings per container
50
UPC/BARCODE
015794053835
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Sugar1 Gram(s)--
Papain28 mg--
Protease24 mg--
Alpha-Amylase24 mg--
Papaya22 mg--

Other ingredients: Fructose, Mannitol, Stearic Acid, Starch, Maltodextrin, Glycine, natural Papaya flavors, Silica, Magnesium Stearate, Cellulose, natural Pineapple flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Yes Kosher

This product is made from real papaya and comes as delicious, chewable wafers.

General Statements

USP - United States Pharmacopoeia

Yes Recycling Packaging Yes Manufacturing Supports Wind Power

Digestive enzymes, such as those naturally found in papaya, papain and protease are essential to the body's absorption of food nutrients.

Available in 200 and 500 wafers.

This product has been manufactured at a GMP Registered facility.

Established 1971

~ Natural digestive enzyme support ~ From whole papaya

Our Pledge of Integrity Authenticity ~ Cleanliness ~ Freshness Consistency ~ Accuracy

Formulation

Yes Certified Vegan by the AVA

Yes Certified Gluten-Free by GFCO.ORG

Certified Gluten-Free

No Yeast or Wheat No Soy, Milk or Salt No Artificial Colors Flavors or Sweeteners

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

K

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults chew four (4) wafers after each meal, up to three times a day.

Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers.

Caution: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

If any adverse reactions occur, stop taking the product and consult your doctor.

Do not accept if seal is broken.

Keep out of reach of children.

Storage

Store in a dry place between 59(0)-86(0) F.

General

Product No. 5383 05J16NL

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Natural Tropical Papaya by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Natural Tropical Papaya label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Natural Tropical Papaya by Country Life

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Wafer(s) Dosage formOther (e.g. Tea Bag) Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Papain

Interacts with
2 drugs
28 mg per serving Form: Papaya

Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food an...

Papain monograph & interactions

Protease

No known
interactions
24 mg per serving Form: Aspergillus oryzae

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease monograph & interactions

Alpha-Amylase

24 mg per serving Form: Aspergillus oryzae

Papaya

Interacts with
92 drugs
22 mg per serving Form: Papaya

Papaya is a tropical fruit that is nutritious and generally safe to eat as food, and it contains an enzyme called papain used as a digestive aid and m...

Papaya monograph & interactions

Other (inactive) ingredients: Fructose, Mannitol, Stearic Acid, Starch, Maltodextrin, Glycine, Natural Papaya flavors, Silica, Magnesium Stearate, Cellulose, Natural Pineapple flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natural Tropical Papaya by Country Life Drug Interactions

Want to check YOUR meds against Natural Tropical Papaya?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
92Drugs
92 Moderate

Ingredients driving the most interactions

Papaya 92
Papain 2

Individual Drug Interactions

The ingredients in Natural Tropical Papaya interact with 92 drugs. Click any drug to see the details.

2 of the 5 ingredients in Natural Tropical Papaya interact with drugs. Each result below shows which ingredient is responsible. Papaya Papain

Each ingredient & the kinds of drugs it affects

For each ingredient in Natural Tropical Papaya with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Papaya4 drug types · 92 drugs

Amiodarone (Cordarone)

Theoretically, papaya extract may increase the levels and clinical effects of amiodarone.
Animal research in rats shows that a single oral dose of papaya extract, as well as multiple doses of papaya extract daily over 14 days, prior to a single dose of amiodarone delays the time to maximum amiodarone concentration. However, only the 14-day papaya extract regimen increases systemic amiodarone exposure by 60% to 70%. This interaction has not been reported in humans.

Likelihood Probable Evidence D
Antidiabetes Drugs

Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects. It is unclear if other forms of papaya have the same effect.
A small low-quality clinical study in patients with type 2 diabetes who are taking glibenclamide shows that taking a fermented papaya preparation 3 grams daily for 2 months decreases fasting and postprandial blood glucose levels when compared to baseline. Additionally, of the 25 patients in the study, 9 required a reduction in glibenclamide dose.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Theoretically, consuming large quantities of papaya fruit can reduce the clinical effects of levothyroxine.
In one case-report, a 37-year-old male with a history of thyroidectomy who was stabilized on levothyroxine for 5 years presented with hypothyroidism after consuming 5-6 papaya fruits daily for 14 days during vacation. In a controlled re-challenge test involving 5-6 papayas daily, the patient remained euthyroid for 7 days, but developed mild hypothyroidism after 14 days. Both times, thyroid levels normalized 40-45 days after discontinuing papaya.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, concomitant use of warfarin with papain-containing papaya extract might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.

Likelihood Possible Evidence D
Papaya full monograph & interactions

Papain1 drug type · 2 drugs

Warfarin (Coumadin)

Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.

Likelihood Possible Evidence D
Papain full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Natural Tropical Papaya, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Natural Tropical Papaya by Country Life: Common Questions

Does Natural Tropical Papaya by Country Life interact with any medications?
Yes. Based on its ingredients, Natural Tropical Papaya has a known interaction with 92 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Natural Tropical Papaya contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Papain and protease safety hasn't been well studied in pregnancy, and unripe papaya and concentrated papain are best avoided. Papaya fruit itself appears likely safe in moderation, but concentrated supplements raise concerns. There isn't enough data to know what's safe at supplement doses—talk with your doctor or pharmacist before taking it.
Can I take this while breastfeeding?
There isn't enough reliable safety information on papain or protease during breastfeeding, and sources recommend avoiding supplemental papain unless advised by a doctor. Papaya fruit itself appears likely safe. Speak with your doctor or pharmacist before starting.
What are the most common side effects?
Allergic reactions are the most common issue—itchy watery eyes, runny nose, sneezing, abdominal cramps, sweating, or diarrhea in people sensitive to papain. Digestive upset is also possible. High doses may cause more serious stomach inflammation or injury.
Does this actually work for the conditions listed?
The evidence isn't established in our data. Papain and papaya both show insufficient reliable evidence for cancer, muscle soreness, skin issues, diabetes, and other claimed uses. You'd want to ask your doctor whether it makes sense for your situation.
What does each ingredient do?
Papain and protease are enzymes that digest protein; alpha-amylase breaks down starch. Papaya fruit contains papain naturally and adds its whole-plant content. The idea is that these enzymes may support digestion, but clinical proof is lacking.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Natural Tropical Papaya is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natural Tropical Papaya label
Go deeper

The Full Monographs Behind Natural Tropical Papaya’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Papain

Interacts with 2 drugs

Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food and laboratory uses, strong human evidence...

Read the full Papain monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Papaya

Interacts with 92 drugs

Papaya is a tropical fruit that is nutritious and generally safe to eat as food, and it contains an enzyme called papain used as a digestive aid and meat tenderizer. Papaya leaf extract is b...

Read the full Papaya monograph →
Sources

Sources & How We Checked

Natural Tropical Papaya's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Papaya 14 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13. PubMed
  6. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
  7. Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
  8. Oderinde, O., Noronha, C., Oremosu, A., Kusemiju, T., and Okanlawon, O. A. Abortifacient properties of aqueous extract of Carica papaya (Linn) seeds on female Sprague-Dawley rats. Niger.Postgrad.Med J 2002;9(2):95-98. DOI
  9. Danese, C., Esposito, D., D'Alfonso, V., Cirene, M., Ambrosino, M., and Colotto, M. Plasma glucose level decreases as collateral effect of fermented papaya preparation use. Clin Ter. 2006;157(3):195-198.
  10. Iliev, D. and Elsner, P. Generalized drug reaction due to papaya juice in throat lozenges. Dermatology 1997;194(4):364-366. PubMed
  11. Andersen HA, Bernatz PE, Grindlay JH. Perforation of the esophagus after use of a digestant agent: report of case and experimental study. Ann Otol Rhinol Laryngol 1959;68:890-6. PubMed
  12. Deiana L, Marini S, Mariotti S. Ingestion of large amounts of papaya fruit and impaired effectiveness of levothyroxine therapy. Endocr Pract 2012;18(1):98-100. PubMed
  13. Rodrigues M, Alves G, Francisco J, Fortuna A, Falcão A. Herb-drug pharmacokinetic interaction between Carica papaya extract and amiodarone in rats. J Pharm Pharm Sci 2014;17(3):302-15. PubMed
  14. Rajapakse S, de Silva NL, Weeratunga P, Rodrigo C, Sigera C, Fernando SD. Carica papaya extract in dengue: a systematic review and meta-analysis. BMC Complement Altern Med. 2019;19(1):265. PubMed

See these in context on the Papaya monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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