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Dietary supplement

Nordic GLA Ingredients & Drug Interactions

by Nordic Naturals

Nordic GLA label
See full label image
Liquid Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Nordic GLA against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Nordic GLA is a dietary supplement by Nordic Naturals with 1 active ingredient. Its ingredients are commonly taken for eczema and dry skin, rheumatoid arthritis, inflammation.Based on those ingredients, 226 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Borage Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Nordic GLA by Nordic Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Nordic GLA by Nordic Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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Computed from our clinical databases

HelloPharmacist Scorecard of Nordic GLA by Nordic Naturals

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

None of the active ingredients could be matched to our evidence database, so intended use can't be graded.

Why this rating?
  • None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Borage Oil” is listed as a grouped ingredient — the label gives one combined amount (2,300 mg) without saying how much of each component you get.
Known Interaction Concern
Not assessable

None of the active ingredients could be matched to our interaction database.

Why this rating?
  • We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
Safety Information
Unable to assess

None of the active ingredients could be matched to our safety data.

Why this rating?
  • We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.

Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Nordic GLA, straight from the product label.

Brand Nordic Naturals
Barcode (UPC) 768990016653
Net contents 4 Fluid Ounce(s); 119 mL
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 223170
Product type Fat/fatty Acid
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Nordic GLA by Nordic Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 mL
Maximum serving Sizes:
2.5 mL
Servings per container
48
UPC/BARCODE
768990016653
IngredientAmount% DV
Calories20 Calorie(s)--
Saturated Fat0 Gram(s)--
Gamma-Linolenic Acid480 mg--
Total Fat2.5 Gram(s)3%
Trans Fat0 Gram(s)--
Borage Oil2300 mg--

Other ingredients: Borage seed oil, D-Alpha-Tocopherol, Rosemary extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

100% vegetarian borage oil

480 mg GLA

Borage oil for healthy skin and joints, and optimal fat metabolism

Formulation

100% vegetarian borage oil

Nordic GLA is a non-GMO, 100% vegetarian borage oil that nourishes skin, promotes immunity and healthy joints, and supports optimal fat metabolism.

Every batch of Nordic Naturals borage oils is tested by a third-party certified lab for environmental toxins, including heavy metals. All borage oils are in the triglyceride form and surpass the strictest international standards for purity and freshness. Certificates of Analysis available upon request.

Radiant skin Flexible joints Fat metabolism

Non GMO

No gluten, milk derivatives, or artificial colors or flavors.

Suggested/Recommended/Usage/Directions

Suggested Use: One-half teaspoon daily, with food, or as directed by your health care professional or pharmacist.

Best if used within 3 months after opening

Precautions

Do not take if tamper-evident seal is broken or missing

Keep out of the reach of children

Warning: Consult with your physician before using this product if you are pregnant or lactating, or use blood thinners.

Storage

Refrigerate after opening

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Non GMO Verified

Third-Party Purity Tested

FDA Statement of Identity

Dietary Supplement

General Statements

Please recycle this container

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Nordic GLA by Nordic Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Nordic GLA label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Nordic GLA by Nordic Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2.5 mL Dosage formLiquid Servings per container48 Amounts shown are per serving.

Borage Oil

Interacts with
226 drugs
2300 mg per serving

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arth...

Borage Oil monograph & interactions
  • › Gamma-Linolenic Acid

Other (inactive) ingredients: Borage seed oil, D-Alpha-Tocopherol, Rosemary extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Nordic GLA by Nordic Naturals Drug Interactions

Nordic GLA contains a single active ingredient, and it has known interactions with 226 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Nordic GLA?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
226Drugs
226 Moderate

Ingredients driving the most interactions

Borage Oil 226

Individual Drug Interactions

The ingredients in Nordic GLA interact with 226 drugs. Click any drug to see the details.

1 of the 1 ingredient in Nordic GLA interact with drugs. Each result below shows which ingredient is responsible. Borage Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Nordic GLA with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Borage Oil3 drug types · 226 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.

Likelihood Possible Evidence D
Borage Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Nordic GLA, from the product label.

Nordic Naturals

See all Nordic Naturals products
Name
Nordic Naturals, Mfg.
Street Address
111 Jennings Drive
City
Watsonville
State
CA
ZipCode
95076
Phone Number
800-662-2544
Web Address
nordicnaturals.com
Pharmacist Counseling Corner

Nordic GLA by Nordic Naturals: Common Questions

Does Nordic GLA by Nordic Naturals interact with any medications?
Yes. Based on its ingredients, Nordic GLA has a known interaction with 226 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Nordic GLA contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Nordic GLA is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Nordic GLA label
Go deeper

The Full Monographs Behind Nordic GLA’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Borage

Interacts with 226 drugs

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...

Read the full Borage monograph →
Sources

Sources & How We Checked

Nordic GLA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Borage 11 references
  1. Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty A PubMed
  2. WHO working group. Pyrrolizidine alkaloids. Environmental Health Criteria, 80. WHO: Geneva, 1988.
  3. Fan YY, Chapkin RS. Importance of dietary gamma-linolenic acid in human health and nutrition. J Nutr 1998;128:1411-4.
  4. Takwale A, Tan E, Agarwal S, et al. Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. BMJ 2003;327:1385. PubMed
  5. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  6. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  7. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  8. Holman CP and Bell AF. A trial of evening primrose oil in the treatment of chronic schizophrenia. J Orhtomolecular Psych 1983;12:302-304.
  9. Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. PubMed
  10. Bard, J. M., Luc, G., Jude, B., Bordet, J. C., Lacroix, B., Bonte, J. P., Parra, H. J., and Duriez, P. A therapeutic dosage (3 g/day) of borage oil supplementation has no effect on platelet aggregation in healthy volunteers. Fundam.Clin.Pharmacol. 1997;1
  11. Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3. PubMed

See these in context on the Borage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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