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Dietary supplement

Oregano Extract Ingredients & Drug Interactions

by The Vitamin Shoppe

Oregano Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oregano Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oregano Extract is a dietary supplement by The Vitamin Shoppe with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oregano Extract by The Vitamin Shoppe

Ask about any prescription or over-the-counter medication and we check it for interactions with Oregano Extract by The Vitamin Shoppe — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oregano Extract by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: oregano extract. Oregano is a culinary herb from the mint family, and the extract concentrates its active compounds—the same ones that give it flavor and aroma in cooking, now in a more potent form.

The capsule also holds inactive ingredients: dicalcium phosphate, gelatin, water, and magnesium stearate. These are standard excipients that hold the extract together and form the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oregano's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: anti-fungal and anti-microbial properties.
  • We looked for evidence on: Tinea capitis, Tinea corporis, Tinea pedis, Intestinal parasite infection, Upper respiratory tract infection (URTI), Bronchitis — and 3 related terms.
  • The closest evidence on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Cough, Intestinal parasite infection, Tinea corporis, and more.

The evidence we hold doesn't establish that oregano extract works for acne, bronchitis, asthma, headache, or upper respiratory tract infections. All of these are rated insufficient reliable evidence to rate—meaning the data we have isn't strong enough to say whether it helps or doesn't.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano used in regular food amounts is generally well tolerated. But this is a concentrated supplement, which is stronger and less studied than what you'd eat on a pizza or in a salad.

The most common side effect from oral use is stomach upset. Rarely, people have had serious allergic reactions, including anaphylaxis (a life-threatening reaction)—especially those sensitive to other plants in the mint family like thyme.

Topical oregano oil can cause skin irritation, particularly in concentrations above 1% or on mucous membranes. During pregnancy, the safety data advises against medicinal or supplement amounts of oregano; food amounts are likely fine.

While breastfeeding, the safety of oregano supplements isn't established, so stick to normal food amounts.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood thinners (anticoagulants) and antiplatelet drugs (like aspirin or warfarin) and your diabetes medications before starting—oregano may increase bleeding risk and lower blood sugar, respectively. Both are moderate-severity concerns based on lab findings.

Use the search tool on this page to confirm your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Oregano extract is worth a second look if you take blood thinners or diabetes medications—check with your own doctor or pharmacist first. If you're pregnant or breastfeeding, talk it over before taking a supplement rather than just eating oregano as a spice.

People with allergies to mint-family plants should be cautious, as serious allergic reactions have been reported.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Extract, straight from the product label.

Brand The Vitamin Shoppe
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Oct 25, 2012
DSLD ID 13045
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Extract by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
100
IngredientAmount% DV
Oregano extract450 mg--

Other ingredients: Dicalcium Phosphate, Gelatin, Water, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

This traditional herbal, oregano extract has been valued for its anti-fungal and anti-microbial properties. This much sought supplement is in a convenient capsule form.

SINCE 1977

Suggested/Recommended/Usage/Directions

Directions As a dietary supplement, take one (1) to three (3) capsules daily, preferably with meals.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Warning Consult your physician prior to use if you are pregnant or nursing.

General

VS-1674 / 1057757

Formulation

Does Not Contain: Yeast, Corn, Wheat, Sugar, Salt, Soy, Starch, Dairy, Citrus, Fish, Preservatives, Artificial Colors or Flavors.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oregano Extract by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oregano Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oregano Extract by The Vitamin Shoppe

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Oregano extract

Interacts with
208 drugs
450 mg per serving Form: Oregano Volatile Oils

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano extract monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Gelatin, Water, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Extract by The Vitamin Shoppe Drug Interactions

Want to check YOUR meds against Oregano Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano extract 208

Individual Drug Interactions

The ingredients in Oregano Extract interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Oregano Extract interact with drugs. Each result below shows which ingredient is responsible. Oregano extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano extract2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oregano Extract, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
The Vitamin Shoppe
Pharmacist Counseling Corner

Oregano Extract by The Vitamin Shoppe: Common Questions

Does Oregano Extract by The Vitamin Shoppe interact with any medications?
Yes. Based on its ingredients, Oregano Extract has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is oregano extract safe during pregnancy?
Food amounts of oregano are likely fine, but the safety data advises against medicinal or supplement doses during pregnancy. Talk with your doctor or pharmacist about what's right for you.
What's the most common side effect?
Stomach upset. Oregano is well tolerated in food amounts, and serious side effects are rare—but allergic reactions, including severe ones, have been reported in sensitive individuals, particularly those with allergies to other mint-family plants.
Why is this a concentrated extract and not just oregano powder?
An extract concentrates the active compounds, making it stronger and more potent than dried herb. That's also why it's less studied in supplement form—we have more safety data on oregano as food than as medicine.
Can I take this if I'm allergic to thyme?
Be cautious. Thyme and oregano are both members of the mint family, and allergic reactions to one can mean reactions to the other. Talk with your doctor or pharmacist before taking it.
Does oregano extract actually help with colds or cough?
The evidence we hold doesn't establish that it works for upper respiratory infections, bronchitis, or asthma—we don't have reliable data to say whether it helps or doesn't.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Extract label
Go deeper

The Full Monographs Behind Oregano Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oregano Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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