Interactions on record — worth a quick check against your medications. Based on 2 of 7 ingredients. Check your meds →
Dietary supplement

PB Assist Jr Natural Strawberry Melon Flavored Ingredients & Drug Interactions

by doTERRA

PB Assist Jr Natural Strawberry Melon Flavored label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PB Assist Jr Natural Strawberry Melon Flavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PB Assist Jr Natural Strawberry Melon Flavored is a dietary supplement by doTERRA with 7 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against PB Assist Jr Natural Strawberry Melon Flavored by doTERRA

Ask about any prescription or over-the-counter medication and we check it for interactions with PB Assist Jr Natural Strawberry Melon Flavored by doTERRA — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of PB Assist Jr Natural Strawberry Melon Flavored by doTERRA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 7 active ingredients.
  • “PB Assist Jr Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

PB Assist Jr is a powder blend of 7 active probiotic and prebiotic ingredients designed to support digestive health. It contains several strains of Lactobacillus and Bifidobacterium — live beneficial bacteria — along with fructooligosaccharides (a type of fiber that feeds the good bacteria in your gut).

The inactive ingredients are sweeteners (xylitol and erythritol), natural strawberry melon flavor, citric acid, and silica.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Probiotic support for digestive and gut health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Irritable bowel syndrome (IBS), Rotaviral diarrhea, Travelers' diarrhea — and 4 related terms.
  • The closest evidence on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Constipation (Natural Medicines).
  • Also on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Travelers' diarrhea.
  • Also on file: Bifidobacterium Breve is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Constipation, Rotaviral diarrhea, Ulcerative colitis, and more.

The evidence for this product's ingredients is still being sorted out. Fructooligosaccharides show insufficient reliable evidence for osteoporosis, constipation, diabetes, travelers' diarrhea, and high cholesterol, meaning studies haven't yet established whether it works for these uses.

Bifidobacterium breve appears possibly ineffective for age-related cognitive decline and sepsis, and shows insufficient evidence for hay fever, antibiotic-associated diarrhea, and atopic disease (allergic conditions). We don't have effectiveness ratings on file for the other probiotic strains in this blend.

The evidence, ingredient by ingredient Fructo-oligosaccharides (fos) Bifidobacterium Breve

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fructooligosaccharides and probiotics are generally well tolerated, but the evidence for supplement doses is limited, so use this product only under your doctor's guidance. The most common side effects from fructooligosaccharides are gas, bloating, and belly pain — though studies show these don't happen more often at doses under 10 grams per day compared to placebo.

Rare cases of Bifidobacterium bacteremia (the bacteria entering the bloodstream) have been reported in critically ill infants and very ill or immunocompromised people. Because safety data for supplements are limited, talk with your healthcare provider before starting, especially if you're very ill or have a weakened immune system.

Pregnancy and breastfeeding safety data for these ingredients aren't on file — discuss with your doctor or pharmacist whether this product is right for you during pregnancy or lactation.

Side effects, ingredient by ingredient Fructo-oligosaccharides (fos) Bifidobacterium Breve

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Bifidobacterium Breve.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, double-check the timing before starting this product — the antibiotics can kill the beneficial bacteria and make the probiotic less effective. For the other ingredients, we couldn't check interaction data, so run your full medication list through the tool below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

PB Assist Jr is a multi-strain probiotic powder meant to support digestive health through live bacteria and prebiotic fiber. If you take antibiotics, separate your doses by a couple of hours so the probiotic isn't killed.

Because the evidence for effectiveness is still limited and safety data for supplement doses are sparse, talk with your doctor or pharmacist before starting, especially if you're ill or have a weakened immune system.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PB Assist Jr Natural Strawberry Melon Flavored, straight from the product label.

Brand doTERRA
Net contents 30 Sachet(s); 60 Gram(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 276384
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PB Assist Jr Natural Strawberry Melon Flavored by doTERRA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Sachet(s)
Maximum serving Sizes:
1 Sachet(s)
Servings per container
30
IngredientAmount% DV
Lactobacillus salivarius0 NP--
Fructooligosaccharides150 mg--
Lactobacillus rhamnosus0 NP--
Bifidobacterium breve0 NP--
Bifidobacterium animalis lactis0 NP--
PB Assist Jr Probiotic Blend0 NP--
Lactobacillus plantarum LP010 NP--
Lactobacillus plantarum LP020 NP--

Other ingredients: Xylitol, Erythritol, natural Strawberry Melon flavor, Citric Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Probiotic Powder

FDA Statement of Identity

Dietary Supplement

General Statements

Net. Wt. 60.0 g Sachets (Total Weight)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions for use Consume the contents of one sachet a day. Pour contents of sachet directly into mouth or mix with 4 oz of water, juice, or preferred beverage and drink immediately. Do not mix with hot water. It can also be mixed with cold foods such as yogurt, smoothies, breakfast cereal, etc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PB Assist Jr Natural Strawberry Melon Flavored by doTERRA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PB Assist Jr Natural Strawberry Melon Flavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PB Assist Jr Natural Strawberry Melon Flavored by doTERRA

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Sachet(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fructooligosaccharides

No known
interactions
150 mg per serving

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...

Fructooligosaccharides monograph & interactions

PB Assist Jr Probiotic Blend

0 NP per serving
  • › Lactobacillus salivarius
  • › Lactobacillus rhamnosus
  • › Bifidobacterium breve
  • › Bifidobacterium animalis lactis
  • › Lactobacillus plantarum LP01
  • › Lactobacillus plantarum LP02

Other (inactive) ingredients: Xylitol, Erythritol, Natural Strawberry Melon flavor, Citric Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

PB Assist Jr Natural Strawberry Melon Flavored by doTERRA Drug Interactions

Want to check YOUR meds against PB Assist Jr Natural Strawberry Melon Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bifidobacterium breve 182

Individual Drug Interactions

The ingredients in PB Assist Jr Natural Strawberry Melon Flavored interact with 182 drugs. Click any drug to see the details.

1 of the 7 ingredients in PB Assist Jr Natural Strawberry Melon Flavored interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium breve

Each ingredient & the kinds of drugs it affects

For each ingredient in PB Assist Jr Natural Strawberry Melon Flavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium breve1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium breve full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PB Assist Jr Natural Strawberry Melon Flavored, from the product label.

doTERRA

See all doTERRA products
Name
doTERRA
Pharmacist Counseling Corner

PB Assist Jr Natural Strawberry Melon Flavored by doTERRA: Common Questions

Does PB Assist Jr Natural Strawberry Melon Flavored by doTERRA interact with any medications?
Yes. Based on its ingredients, PB Assist Jr Natural Strawberry Melon Flavored has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PB Assist Jr Natural Strawberry Melon Flavored contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the bacteria in this product supposed to do?
The Lactobacillus and Bifidobacterium strains are live, beneficial bacteria meant to support your gut health and digestion. The fructooligosaccharides act as a prebiotic — food for those good bacteria — to help them thrive.
Will this help with my specific digestive issue?
The evidence isn't settled yet. Studies so far show we don't have reliable proof that fructooligosaccharides or Bifidobacterium breve work for constipation, diarrhea, allergies, or other conditions — that's why we rate them as having insufficient evidence. Talk with your doctor about whether this is right for your situation.
What side effects might I get?
Gas, bloating, belly pain, and flatulence are the most commonly reported — usually mild. These tend to happen at higher doses, though studies suggest they're no more common than placebo at doses under 10 grams per day of fructooligosaccharides. If you're very ill or immunocompromised, talk with your doctor first, since rare serious infections have been reported with probiotic use in those groups.
Can I take this while I'm on antibiotics?
Not at the same time. Antibiotics kill bacteria — including the beneficial ones in this product — which makes the probiotic less effective. Separate your antibiotic dose and this powder by at least a couple of hours.
Is it safe to take during pregnancy or breastfeeding?
We don't have safety information on file for these ingredients during pregnancy or lactation. Talk with your doctor or pharmacist to decide whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PB Assist Jr Natural Strawberry Melon Flavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PB Assist Jr Natural Strawberry Melon Flavored label
Go deeper

The Full Monographs Behind PB Assist Jr Natural Strawberry Melon Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph →
Sources

Sources & How We Checked

PB Assist Jr Natural Strawberry Melon Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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