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Dietary supplement

Pearl Tomato 400 mg Ingredients & Drug Interactions

by Solumeve

Pearl Tomato 400 mg label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pearl Tomato 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pearl Tomato 400 mg is a dietary supplement by Solumeve with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, skin and hair health, liver support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Cysteine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pearl Tomato 400 mg by Solumeve

Ask about any prescription or over-the-counter medication and we check it for interactions with Pearl Tomato 400 mg by Solumeve — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pearl Tomato 400 mg by Solumeve

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Pearl Tomato contains 2 active ingredients: L-cysteine, an amino acid, and white tomato fruit extract. L-cysteine is a building block your body uses to make protein and other compounds.

White tomato fruit extract is derived from the tomato fruit itself and concentrates compounds naturally present in tomatoes. The capsule also contains several inactive ingredients—modified cellulose, calcium carbonate, microcrystalline cellulose, magnesium stearate, and silicon dioxide—which are standard binders, fillers, and flow agents used to hold the supplement together and fill the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: skin health and appearance support.
  • We looked for evidence on: Aging skin, Radiation dermatitis, skin photoprotection, skin antioxidant defense.
  • The closest evidence on file: Tomato is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Tomato is rated "Insufficient Reliable Evidence To Rate" for Radiation dermatitis.

The evidence for what this supplement can actually do is very limited. L-cysteine has been studied for androgenic alopecia (male or female pattern hair loss), venous leg ulcers, hangover, stroke, and gastritis, but the data is not strong enough to say whether it works for any of these.

White tomato fruit extract appears ineffective for bladder cancer and breast cancer; for diabetes, high cholesterol (hyperlipidemia), exercise-induced asthma, and benign prostatic hyperplasia (BPH—prostate enlargement), the evidence is also insufficient to know whether it helps. In short, we don't have reliable data showing this product is effective for the conditions it might be marketed for.

The evidence, ingredient by ingredient L-cysteine Tomato

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-cysteine from food is generally well tolerated, but the long-term safety of high-dose supplements isn't well studied, so caution is advised. White tomato fruit extract, including the extract used here, is generally well tolerated in typical amounts.

However, tomatine—a compound in tomato leaves and unripe green tomatoes—can cause serious side effects like dizziness, headache, mild muscle spasms, or diarrhea if consumed in very large amounts, though this is rare with ripe tomato fruit. Some people have reported airborne allergies to tomato stem proteins, though this is uncommon and separate from food allergy to the fruit itself.

Both L-cysteine and white tomato fruit extract are rated likely safe in pregnancy and lactation based on the data we hold, but high-dose L-cysteine supplement safety over time has not been well studied, so talk with your doctor or pharmacist if you're pregnant or nursing and considering this product.

Side effects, ingredient by ingredient L-cysteine Tomato

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — L-cysteine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs—insulin, metformin, sulfonylureas, or any other blood-sugar medication—double-check this product with your doctor or pharmacist first. L-cysteine may increase the risk of low blood sugar (hypoglycemia) when combined with these medications.

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Pearl Tomato may be worth a conversation if you're interested in tomato or cysteine supplementation, but the evidence that it actually works for any specific condition isn't strong. The main concern is if you take antidiabetes medication—the L-cysteine in this product could theoretically lower your blood sugar further.

If you take any blood-sugar medication, check with your doctor or pharmacist before starting. Overall, this is a supplement where the data is limited on both efficacy and long-term safety of supplement-dose amounts.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pearl Tomato 400 mg, straight from the product label.

Brand Solumeve
Barcode (UPC) 898220018208
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 299025
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pearl Tomato 400 mg by Solumeve, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
898220018208
IngredientAmount% DV
L-Cysteine25 mg--
White Tomato Fruit Extract400 mg--

Other ingredients: Modified Cellulose, Calcium Carbonate, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Solumeve A healthy look starts from within

Solumeve is a registered trademark of Madre Labs, LLC

Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 capsule daily, or as recommended by health care practitioner.

Formulation

Formulated without: Gluten GMOs Soy

This product is not manufactured with milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten.

Precautions

Warning: Keep out of reach of children.

Consult your healthcare practitioner before using this product, especially if you are pregnant, nursing, have existing medical conditions or taking prescription medications.

Sealed for your protection. Do not use if seal is missing or broken.

This product is not manufactured with milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pearl Tomato 400 mg by Solumeve label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pearl Tomato 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pearl Tomato 400 mg by Solumeve

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Cysteine

Interacts with
86 drugs
25 mg per serving

L-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and su...

L-Cysteine monograph & interactions

White Tomato Fruit Extract

No known
interactions
400 mg per serving Form: Solanum lycopersicum Fruit Extract

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people...

White Tomato Fruit Extract monograph & interactions

Other (inactive) ingredients: Modified Cellulose, Calcium Carbonate, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pearl Tomato 400 mg by Solumeve Drug Interactions

Want to check YOUR meds against Pearl Tomato 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

L-Cysteine 86

Individual Drug Interactions

The ingredients in Pearl Tomato 400 mg interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Pearl Tomato 400 mg interact with drugs. Each result below shows which ingredient is responsible. L-Cysteine

Each ingredient & the kinds of drugs it affects

For each ingredient in Pearl Tomato 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Cysteine1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that L-cysteine can have hypoglycemic effects.

Likelihood Possible Evidence D
L-Cysteine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pearl Tomato 400 mg, from the product label.

Solumeve

See all Solumeve products
Name
Madre Labs, LLC
Street Address
301 N. Lake Ave. #500
City
Pasadena
State
CA
ZipCode
91101
Web Address
www.solumeve.com
Pharmacist Counseling Corner

Pearl Tomato 400 mg by Solumeve: Common Questions

Does Pearl Tomato 400 mg by Solumeve interact with any medications?
Yes. Based on its ingredients, Pearl Tomato 400 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pearl Tomato 400 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this supplement actually work for hair loss, stroke, or any specific condition?
The evidence we have isn't strong enough to say. Both L-cysteine and white tomato extract have been studied for several conditions—hair loss, ulcers, cancer, diabetes, and others—but the data is either insufficient or shows they may not work. If you're considering this for a specific health issue, talk with your doctor about whether there's better evidence for other options.
Is this safe if I'm pregnant or breastfeeding?
Both ingredients are rated likely safe in pregnancy and lactation based on the data we hold. That said, high-dose L-cysteine supplement safety over time hasn't been well studied, so it's worth a conversation with your doctor or pharmacist to make sure it's right for your situation.
Can I be allergic to the tomato in this product?
Most people tolerate tomato fruit well. Rarely, some people develop airborne allergies to tomato stem proteins (not the fruit itself). If you have a known tomato allergy or have had unusual reactions to tomato products before, check with your pharmacist before taking this.
What is L-cysteine and why is it in this product?
L-cysteine is an amino acid—a building block your body uses to make protein and other compounds. It's included in this supplement because some research suggests it *might* support certain conditions, though the evidence isn't reliable yet. It's naturally present in foods like garlic, onions, and poultry.
I take metformin for diabetes. Is this safe to combine with it?
Animal research suggests L-cysteine can lower blood sugar, so taking it with metformin or any other diabetes medication might increase your risk of low blood sugar. Before you start this supplement, check with your doctor or pharmacist—they can tell you whether it's okay or if you need any monitoring.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pearl Tomato 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pearl Tomato 400 mg label
Go deeper

The Full Monographs Behind Pearl Tomato 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-cysteine

Interacts with 86 drugs

L-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and supplements are usually well tolerated, bu...

Read the full L-cysteine monograph → Herb & supplement monograph

Tomato

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supple...

Read the full Tomato monograph →
Sources

Sources & How We Checked

Pearl Tomato 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-cysteine 2 references
  1. Dowlati Y, Maheux M, Meyer JH. The effect of oral L-cysteine on breast milk and plasma cysteine concentrations. Neuropsychiatr Dis Treat 2020;16:3163-3172.
  2. Lee S, Han KH, Nakamura Y, et al. Dietary L-cysteine improves the antioxidative potential and lipid metabolism in rats fed a normal diet. Biosci Biotechnol Biochem 2013;77(7):1430-4.

See these in context on the L-cysteine monograph →

Tomato 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Asero R, Mistrello G, Amato S. Airborne allergy to tomato proteins. Allergy. 2010;65(12):1626-7. PubMed
  3. Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed

See these in context on the Tomato monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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