Phosphatidylserine Ingredients & Drug Interactions
by Absonutrix
What is this page for?
First and foremost: checking Phosphatidylserine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phosphatidylserine is a dietary supplement by Absonutrix with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Phosphatidylserine by Absonutrix
Ask about any prescription or over-the-counter medication and we check it for interactions with Phosphatidylserine by Absonutrix — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Phosphatidylserine by Absonutrix
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product has three active ingredients. Phosphatidylserine (listed here as both L-a-Phosphatidyl-L-serine and as a blend component) is thought to support brain function and may help with memory in older age.
L-a-Phosphatidylcholine is a compound related to choline, an important nutrient for nerve and brain health. The capsules also contain inactive ingredients — cellulose, magnesium stearate, and gellan gum — which are standard binders and capsule materials.
Does it work?
Moderate evidence
The evidence for phosphatidylserine is strongest for age-related cognitive decline and Alzheimer disease, where it's rated Possibly Effective based on available studies. For other uses — athletic performance, ADHD, general cognitive function, and dementia — the evidence isn't solid enough to rate yet.
Phosphatidylcholine shows Possibly Effective evidence for ulcerative colitis. For its other studied uses — liver disease, Alzheimer disease, and anxiety — evidence is still insufficient.
How safe is it?
Well-documented data
Phosphatidylserine is generally well tolerated, though long-term safety hasn't been fully studied. The most common side effects are flatulence, stomach upset, headache, insomnia, and nausea — insomnia is more likely at higher doses (600 mg).
Phosphatidylcholine is also well tolerated in food and supplement amounts, though high doses can cause digestive upset. At very high doses (30 grams per day), you might see diarrhea, bloating, or nausea; more modest amounts can still cause altered taste, nausea, or vomiting in some people.
For pregnancy: there isn't enough safety data for phosphatidylserine, so it's best to avoid it. Phosphatidylcholine's safety as a supplement in pregnancy hasn't been well studied — while choline itself is needed, talk with your doctor before taking supplements.
Breastfeeding safety is unknown for both ingredients; speak with your healthcare provider first.
Meds to double-check
Moderate interaction found
Check with your pharmacist before using this if you take anticholinergic drugs (medications that block acetylcholine activity) or cholinergic drugs (that increase it). Both are Moderate-severity interactions.
The ingredient Maltodextrin hasn't been checked for interactions, so your pharmacist should verify your full medication list.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Phosphatidylserine may help with memory and thinking in aging, but it can interact with medications that affect acetylcholine. If you take any anticholinergic or cholinergic drugs — or any prescription medications — check them with your pharmacist before you start.
Watch for stomach upset or insomnia, especially at higher doses.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phosphatidylserine, straight from the product label.
| Brand | Absonutrix |
|---|---|
| Barcode (UPC) | 709257078113 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 293438 |
| Product type | Fat/fatty Acid |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phosphatidylserine by Absonutrix, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Maltodextrin | 0 NP | -- |
| Phosphatidylserine | 515 mg | -- |
| L-a-Phosphatidyl-L-serine | 0 NP | -- |
| L-a-Phosphatidylcholine | 0 NP | -- |
Other ingredients: Cellulose, Magnesium Stearate, Gellan Gum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take one (1) capsule daily, preferably with a meal or as directed by your healthcare professional.
Precautions
Caution: Pregnant or nursing women, children under the age of 18 or individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Caution: Pregnant or nursing women, children under the age of 18 or individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Discontinue use if you experience any adverse reaction to this product. Do not consume more than 5 capsules per day.
Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Store in a cool, dry place.
Seals/Symbols
Made in USA
General Statements
Please recycle.
Formulation
High quality Made in the USA
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phosphatidylserine by Absonutrix label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phosphatidylserine by Absonutrix
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Phosphatidylserine
Interacts with219 drugs
Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...
Phosphatidylserine monograph & interactions- › Maltodextrin
- › L-a-Phosphatidyl-L-serine
- › L-a-Phosphatidylcholine
Other (inactive) ingredients: Cellulose, Magnesium Stearate, Gellan Gum. These complete the product’s ingredient list but are not active constituents.
Phosphatidylserine by Absonutrix Drug Interactions
HelloPharmacist Interaction Report
Phosphatidylserine by Absonutrix contains an active ingredient (L-a-Phosphatidyl-L-serine) that's documented to interact with medications.
The main concern is anticholinergic drugs — medications that block a brain chemical called acetylcholine. Phosphatidylserine is thought to raise acetylcholine levels, which could theoretically reduce how well these drugs work.
This is rated a Moderate interaction.
Read the full breakdown — every affected drug type, severity by severity
Another group to watch is cholinergic drugs (medications that increase acetylcholine activity). Phosphatidylserine might add to their effect, creating extra cholinergic activity.
This is also Moderate severity.
We also have a second active ingredient, L-a-Phosphatidylcholine, which we've checked and found no documented interactions for.
One more ingredient, Maltodextrin, we couldn't check — we hold no data on it. Altogether, these interactions span 218 individual medications.
Before you start, run your exact prescriptions through the checker below.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Phosphatidylserine?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Phosphatidylserine interact with 219 drugs. Click any drug to see the details.
1 of the 1 ingredient in Phosphatidylserine interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine
AmifampridineRuzurgi
How Amifampridine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Amifampridine interactionAmifampridine PhosphateFirdapse
How Amifampridine Phosphate interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Amifampridine Phosphate interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Aminoglutethimide interactionAmitriptylineElavil
How Amitriptyline interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Amitriptyline, Perphenazine interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAtropineSal-Tropine
How Atropine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine interactionAtropine Methyl Nitrate, Digestive EnzymesFestalan
How Atropine Methyl Nitrate, Digestive Enzymes interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine Methyl Nitrate, Digestive Enzymes interactionAtropine SulfateAtropine Sulfate, Isopto Atropine
How Atropine Sulfate interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine Sulfate interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, PhenylAtrosept
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl SalicylateUrinary Antiseptic 2, Urised
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAtropine, DifenoxinMotofen
How Atropine, Difenoxin interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Difenoxin interactionAtropine, DiphenoxylateLofene, Lomotil
How Atropine, Diphenoxylate interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Diphenoxylate interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, ScopolamineColytrol
How Atropine, Hyoscyamine, Scopolamine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Hyoscyamine, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Phenobarbital interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Atropine, Morphine Sulfate interactionBarbital, Hyoscyamine, Scopolamine, Passiflora, ValeriBarbatose #2
How Barbital, Hyoscyamine, Scopolamine, Passiflora, Valeri interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Barbital, Hyoscyamine, Scopolamine, Passiflora, Valeri interactionBelladonna Alkaloids (prescription Drug)Bellafoline
How Belladonna Alkaloids (prescription Drug) interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Belladonna Alkaloids (prescription Drug) interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna Alkaloids, PhenobarbitalBarbidonna, Donnatal
How Belladonna Alkaloids, Phenobarbital interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Belladonna Alkaloids, Phenobarbital interactionBelladonna Extract, Butabarbital SodiumButibel
How Belladonna Extract, Butabarbital Sodium interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Belladonna Extract, Butabarbital Sodium interactionBelladonna Extract, PhenobarbitalBelap
How Belladonna Extract, Phenobarbital interacts with Phosphatidylserine — through 1 ingredient. Tap an ingredient for the detail:
L-a-phosphatidyl-l-serineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full L-a-phosphatidyl-l-serine + Belladonna Extract, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Phosphatidylserine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Phosphatidylserine
Anticholinergic Drugs
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.
Cholinergic Drugs
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.
Brand information
Manufacturer and brand details for Phosphatidylserine, from the product label.
Absonutrix
See all Absonutrix products- Name
- Absonutrix
- Street Address
- 8905 West Market Street
- City
- Colfax
- State
- NC
- ZipCode
- 27235
- Phone Number
- 1-855-368-8749
- Web Address
- www.absonutrix.com
Phosphatidylserine by Absonutrix: Common Questions
Does Phosphatidylserine by Absonutrix interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my memory?
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What side effects might I get?
Can I breastfeed while taking this?
What exactly is phosphatidylserine?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phosphatidylserine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phosphatidylserine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Phosphatidylserine
Interacts with 219 drugsPhosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...
Read the full Phosphatidylserine monograph → Herb & supplement monographPhosphatidylcholine
Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...
Read the full Phosphatidylcholine monograph →Sources & How We Checked
Phosphatidylserine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 24 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylserine 9 references
- Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
- Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
- Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
- Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
- Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
- Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
- Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
- Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
- Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed
Phosphatidylcholine 15 references
- Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
- Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
- Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
- Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
- Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
- Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
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