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Dietary supplement

Ba-Co-Flor Ingredients & Drug Interactions

by Marco Pharma Int'l

Ba-Co-Flor label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ba-Co-Flor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ba-Co-Flor is a dietary supplement by Marco Pharma Int'l with 1 active ingredient. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus coagulans bacteria. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ba-Co-Flor by Marco Pharma Int'l

Ask about any prescription or over-the-counter medication and we check it for interactions with Ba-Co-Flor by Marco Pharma Int'l — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Ba-Co-Flor by Marco Pharma Int'l

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Bacillus Coagulans Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Ba-Co-Flor contains one active ingredient: a proprietary blend of Bacillus coagulans bacteria, a live probiotic organism. The capsule also holds inactive ingredients — magnesium stearate, maltodextrin, microcrystalline cellulose, and water — which serve as fillers and binders to hold the capsule together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: probiotic dietary supplement.
  • We looked for evidence on: Constipation, Diarrhea, Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), Antibiotic-associated diarrhea — and 4 related terms.
  • The strongest evidence on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Diarrhea, Dyspepsia, Flatulence, and more.

The evidence for Bacillus coagulans is mixed. It's rated Possibly Effective for constipation and irritable bowel syndrome (IBS) — meaning there's some promising data, but we'd like to see more.

For antibiotic-associated diarrhea, athletic performance, cancer, and nonalcoholic fatty liver disease, the evidence is either too thin or too unreliable for us to rate it at all. Talk to your doctor about whether this product might help your particular situation.

The evidence, ingredient by ingredient Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus coagulans is generally well tolerated in healthy adults, though the quality and safety data vary across different products. The safety information we have is limited, so it's wise to check with your doctor or pharmacist before you start, especially if you have any chronic health issues.

One important caution: because this is a live probiotic product, there's a theoretical risk of serious infection (bacteremia or sepsis) in people who are severely ill, have a weakened immune system, have indwelling catheters, or are premature infants. Healthy people with intact immune systems who don't have catheters appear to be at very low risk.

If you're in a high-risk group, talk it over with your doctor before taking it.

Side effects, ingredient by ingredient Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotics are the one medication type we've documented to interact with Bacillus coagulans — the bacteria may be killed off if you take them together. Separate your doses by timing them apart, and ask your doctor or pharmacist how much time to leave between them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Ba-Co-Flor may help with constipation or IBS, but the evidence is still developing. If you're on antibiotics, space out your doses — don't take them at the same time.

If you're severely ill, immunocompromised, or have a central line, check with your doctor first. Talk to your doctor or pharmacist about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ba-Co-Flor, straight from the product label.

Brand Marco Pharma Int'l
Net contents 60 Veggie Cap(s)
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 25226
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Children (All), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ba-Co-Flor by Marco Pharma Int'l, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Cap(s)
Maximum serving Sizes:
3 Veggie Cap(s)
Servings per container
20
IngredientAmount% DV
Proprietary Bacillus Coagulans Blend0 Not Present--
Bacillus coagulans bacteria0 NP--

Other ingredients: Magnesium Stearate, Maltodextrin, Microcrystalline Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Dairy Free

Seals/Symbols

+{arrow}

MPI

Suggested/Recommended/Usage/Directions

Suggested Use: Adults take 1 to 3 caps before a meal three times daily as a Probiotic Dietary Supplement*. Reducing the amount to a maintenance level of 2 caps daily. Capsules may be opened and added to food. Children receive 1/2 or less of the adult amount.

Precautions

Tamper evident: Do not use this product if the tamper evident shrink band with the MPI logo is broken or missing from base of cap.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Probiotic Dietary Supplement*

Formula

250 Million Per Capsule

General Statements

Survives Stomach Acid

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ba-Co-Flor by Marco Pharma Int'l label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ba-Co-Flor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ba-Co-Flor by Marco Pharma Int'l

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Cap(s) Dosage formCapsule Servings per container20 Amounts shown are per serving.

Proprietary Bacillus Coagulans Blend

0 Not Present per serving

Other (inactive) ingredients: Magnesium Stearate, Maltodextrin, Microcrystalline Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ba-Co-Flor by Marco Pharma Int'l Drug Interactions

Want to check YOUR meds against Ba-Co-Flor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bacillus coagulans bacteria 182

Individual Drug Interactions

The ingredients in Ba-Co-Flor interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in Ba-Co-Flor interact with drugs. Each result below shows which ingredient is responsible. Bacillus coagulans bacteria

Each ingredient & the kinds of drugs it affects

For each ingredient in Ba-Co-Flor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacillus coagulans bacteria1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans bacteria full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ba-Co-Flor, from the product label.

Marco Pharma Int'l

See all Marco Pharma Int'l products
Name
Marco Pharma Int'l
City
Roseburg
State
OR
ZipCode
97470
Pharmacist Counseling Corner

Ba-Co-Flor by Marco Pharma Int'l: Common Questions

Does Ba-Co-Flor by Marco Pharma Int'l interact with any medications?
Yes. Based on its ingredients, Ba-Co-Flor has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ba-Co-Flor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this work if I'm taking an antibiotic?
Not as well if you take them at the same time — the antibiotic will kill the live bacteria in the probiotic. Ask your pharmacist or doctor how long to wait between doses; spacing them out should let the probiotic work.
What does Bacillus coagulans actually do?
It's a live probiotic bacterium that may help with constipation or irritable bowel syndrome, though the evidence is promising but not yet strong. The exact way it works isn't fully understood.
Is it safe if I'm pregnant or breastfeeding?
The product facts don't include safety data for pregnancy or breastfeeding, so we don't have enough information to say either way. Talk to your doctor or pharmacist for personalized advice.
Can this cause an infection?
In rare cases, live probiotics have caused serious infections in people who are severely ill, have a weakened immune system, or have central catheters. If you're generally healthy with a working immune system and no indwelling lines, the risk is very low. If you're in a higher-risk group, check with your doctor first.
Does it have fillers?
Yes, the capsule contains magnesium stearate, maltodextrin, and microcrystalline cellulose as inactive ingredients to bind and fill the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ba-Co-Flor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ba-Co-Flor label
Go deeper

The Full Monographs Behind Ba-Co-Flor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph →
Sources

Sources & How We Checked

Ba-Co-Flor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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