Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Kiddi-Flora Ingredients & Drug Interactions

by Marco Pharma Int'l

Kiddi-Flora label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kiddi-Flora against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kiddi-Flora is a dietary supplement by Marco Pharma Int'l with 3 active ingredients. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus sporogenes. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kiddi-Flora by Marco Pharma Int'l

Ask about any prescription or over-the-counter medication and we check it for interactions with Kiddi-Flora by Marco Pharma Int'l — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kiddi-Flora by Marco Pharma Int'l

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Kiddi-Flora has 3 active ingredients: two probiotics — Lactobacillus sporogenes and Bacillus coagulans — plus a prebiotic fiber called Nutraflora FOS. The probiotics are live, beneficial bacteria meant to support gut health.

The FOS acts as food for those bacteria, helping them thrive. The tablet also contains inactive ingredients like cellulose, fructose, natural raspberry flavor, and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive and gut health support.
  • We looked for evidence on: Constipation, Diarrhea, Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), Bloating — and 1 related terms.
  • The strongest evidence on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Constipation, Travelers' diarrhea.

The probiotics in Kiddi-Flora (Lactobacillus sporogenes and Bacillus coagulans) are possibly effective for constipation and irritable bowel syndrome (IBS). For other uses like antibiotic-associated diarrhea, athletic performance, cancer prevention, and fatty liver disease, the evidence isn't established in our data.

As for Nutraflora FOS, we don't have enough evidence to rate it for any of the conditions listed — osteoporosis, constipation, diabetes, travelers' diarrhea, or high cholesterol — so talk with your child's doctor about what it might help with.

The evidence, ingredient by ingredient Bacillus Coagulans Fructo-oligosaccharides (fos)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both Lactobacillus sporogenes and Bacillus coagulans are generally well tolerated in healthy children, though the quality and evidence base for probiotic products vary widely. There's a theoretical concern that live probiotics could cause serious infection in kids who are severely ill, immunocompromised, or have central lines in place — if that applies to your child, check with their doctor before starting.

Nutraflora FOS is generally well tolerated in food amounts, but at supplement doses it can cause bloating, gas, abdominal pain, and constipation, especially at higher doses — these symptoms are usually mild under 10 grams per day. The product facts note that safety data for this supplement is limited, so talk with your doctor or pharmacist before giving it to your child.

Side effects, ingredient by ingredient Bacillus Coagulans Fructo-oligosaccharides (fos)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If your child is on antibiotics, don't give Kiddi-Flora at the same time. Separate the doses by a few hours so the antibiotic doesn't kill off the beneficial bacteria.

Antibiotic drugs are the only medication type we've documented an interaction with for this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Kiddi-Flora's probiotics are possibly helpful for constipation and IBS, but the main thing to watch for is any antibiotics your child is on — timing matters, so space them out. The prebiotic fiber may cause some gas or bloating at first.

Before you start, chat with your child's doctor or pharmacist to make sure it fits their health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kiddi-Flora, straight from the product label.

Brand Marco Pharma Int'l
Net contents 60 Chewblet(s)(TM)
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 25294
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Children (All)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kiddi-Flora by Marco Pharma Int'l, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chewblet(s)(TM)
Maximum serving Sizes:
3 Chewblet(s)(TM)
Servings per container
20
IngredientAmount% DV
Lactobacillus sporogenes150000000 {Unit(s)}--
Bacillus coagulans350 FCC Unit(s)--
Nutraflora FOS200 mg--

Other ingredients: Cellulose, Fructose, natural Raspberry flavor, magnesium stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Chew (or dissolve in mouth) 1-3 Chewblets(TM) per day or as directed. For small children, break the Chewblet(TM) into small pieces.

Precautions

Warning: Keep out of reach of children.

Storage

Keep in a cool, dry place.

General Statements

CHEWABLE PROBIOTIC

Seals/Symbols

MPI

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kiddi-Flora by Marco Pharma Int'l label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kiddi-Flora label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kiddi-Flora by Marco Pharma Int'l

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Chewblet(s)(TM) Dosage formTablet Or Pill Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lactobacillus sporogenes

Interacts with
182 drugs
150000000 {Unit(s)} per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

Lactobacillus sporogenes monograph & interactions

Bacillus coagulans

Interacts with
182 drugs
350 FCC Unit(s) per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

Bacillus coagulans monograph & interactions

Nutraflora FOS

No known
interactions
200 mg per serving

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...

Nutraflora FOS monograph & interactions

Other (inactive) ingredients: Cellulose, Fructose, Natural Raspberry flavor, Magnesium stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kiddi-Flora by Marco Pharma Int'l Drug Interactions

Want to check YOUR meds against Kiddi-Flora?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus sporogenes 182

Individual Drug Interactions

The ingredients in Kiddi-Flora interact with 182 drugs. Click any drug to see the details.

1 of the 3 ingredients in Kiddi-Flora interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus sporogenes

Each ingredient & the kinds of drugs it affects

For each ingredient in Kiddi-Flora with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus sporogenes1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus sporogenes full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kiddi-Flora, from the product label.

Marco Pharma Int'l

See all Marco Pharma Int'l products
Name
Marco Pharma Int'l
City
Roseburg
State
OR
ZipCode
97470
Pharmacist Counseling Corner

Kiddi-Flora by Marco Pharma Int'l: Common Questions

Does Kiddi-Flora by Marco Pharma Int'l interact with any medications?
Yes. Based on its ingredients, Kiddi-Flora has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kiddi-Flora contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give Kiddi-Flora to my child while they're on an antibiotic?
You can, but timing is key. Antibiotics can kill the live bacteria in the probiotic, making it less effective. Space out the doses — give the antibiotic and Kiddi-Flora a few hours apart. Ask your child's doctor or pharmacist for the best schedule.
Will Kiddi-Flora cause side effects?
The probiotics are generally well tolerated. The prebiotic fiber (Nutraflora FOS) is the more likely culprit for bloating, gas, and abdominal discomfort, especially at higher doses — these symptoms are usually mild. If your child has a weakened immune system or a central line in place, talk to their doctor first.
Is Kiddi-Flora safe during pregnancy and breastfeeding?
The product facts don't include safety data for pregnancy or breastfeeding. Talk with your doctor or pharmacist to see if it's right for you or your nursing child.
Does Kiddi-Flora actually work for constipation or IBS?
The probiotics in it are possibly effective for both constipation and IBS based on the evidence we have. The prebiotic fiber doesn't have enough evidence behind it yet, so don't expect that to do the heavy lifting.
What exactly are these ingredients?
Lactobacillus sporogenes and Bacillus coagulans are live, beneficial bacteria (probiotics) that help support gut health. Nutraflora FOS is a prebiotic fiber that feeds those good bacteria so they can grow.
Should I worry about the inactive ingredients?
The inactive ingredients — cellulose, fructose, natural raspberry flavor, and magnesium stearate — are common tablet fillers and binders. If your child has a fructose sensitivity, let your doctor know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kiddi-Flora label
Go deeper

The Full Monographs Behind Kiddi-Flora’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph → Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph →
Sources

Sources & How We Checked

Kiddi-Flora's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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