Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Pine Pollen & Lion's Mane Ingredients & Drug Interactions

by Raw Forest Foods

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pine Pollen & Lion's Mane is a dietary supplement by Raw Forest Foods with 3 active ingredients. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pine Pollen & Lion's Mane by Raw Forest Foods

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 3 active ingredients: raw pine pollen, lion's mane extract, and pine pollen extract. Lion's mane is a medicinal mushroom whose extract is the one we have effectiveness data for.

Pine pollen has been used traditionally, though we don't hold interaction or efficacy information for either form of it. The capsule also contains cellulose as an inactive filler.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lion's Mane Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Memory, cognitive support, and nerve health.
  • We looked for evidence on: Memory, Cognitive function, Cognitive impairment, Dementia, Alzheimer disease, Parkinson disease — and 4 related terms.
  • The closest evidence on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Cognitive impairment, Dementia, Memory, and more.

Lion's mane extract has been studied for Alzheimer disease, anxiety, athletic performance, cancer, cognitive function, and cognitive impairment — but the evidence for all of these is insufficient to rate. That means we don't have enough reliable data yet to say whether it works for any of those uses.

Pine pollen's effectiveness isn't established in our data.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lion's mane is generally well tolerated when eaten as food, though long-term supplement safety hasn't been well studied. The most common side effects are gastrointestinal discomfort, nausea, and skin rash.

The safety data advises against use during pregnancy and breastfeeding because there isn't enough information about risks. We don't have safety data on file for pine pollen or pine pollen extract.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this if you're on blood thinners or antiplatelet drugs (like warfarin or aspirin), diabetes medications, or immunosuppressive drugs — lion's mane extract has documented interactions with all three. The risks range from increased bleeding to changes in blood sugar control to reduced immune suppression.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This blend may appeal to people looking for cognitive or immune support, but the evidence for those uses isn't established yet. If you take blood thinners, diabetes drugs, or immunosuppressants, you need to check with your pharmacist first — lion's mane may interfere with how they work.

Anyone pregnant or breastfeeding should also have a conversation with their doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pine Pollen & Lion's Mane, straight from the product label.

Brand Raw Forest Foods
Barcode (UPC) 850004627105
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 309794
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pine Pollen & Lion's Mane by Raw Forest Foods, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
40
UPC/BARCODE
850004627105
IngredientAmount% DV
Pine Pollen, Raw472.5 mg--
Lion's Mane Extract540 mg--
Pine Pollen Extract337.5 mg--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

This is our profoundly restorative and deeply renewing alchemical blend of Mountain Harvest RAW Pine Pollen and full potency, full spectrum, unstandardized extracts of Pine Pollen and organic Lion's Mane. Together, these well-respected tonics offer endocrine, cognitive, and immune support.

General Statements

Using hand-selected, premiere ingredients, our products are professionally - and artfully - crafted to meet our discerningly high standards. We invite you to discover the infinite power within.

Discover the Infinite Power Within

Formulated by Master Herbalists

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take three (3) capsules daily, preferably on an empty stomach. As with all dietary supplements, please consult a qualified healthcare practitioner prior to use.

Precautions

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

May contain traces of maltodextrin (used as part of the extraction process).

Caution: Do not exceed recommended dose.

Storage

Store at room temperature.

Formulation

Vegan

Mountain harvest Clinical grade Unstandardized Elevated extracts Elite endocrine, cognitive, & immune support

No fillers, no drying agents. Never irradiated. This product is GMO free, vegan/vegetarians, and has been manufactured in the USA in an FDA, cGMP certified facility.

This product is GMO free, vegan/vegetarian, and has been manufactured in the USA in an FDA, cGMP certified facility.

This product is GMO free, vegan/vegetarian, and has been manufactured in the USA in an FDA, cGMP certified facility.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Pine Pollen & Lion's Mane by Raw Forest Foods label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pine Pollen & Lion's Mane by Raw Forest Foods

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pine Pollen, Raw

472.5 mg per serving Form: Pinus massoniana, Raw

Lion's Mane Extract

Interacts with
327 drugs
540 mg per serving

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane Extract monograph & interactions

Pine Pollen Extract

337.5 mg per serving Form: Pinus massoniana Extract

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pine Pollen & Lion's Mane by Raw Forest Foods Drug Interactions

Want to check YOUR meds against Pine Pollen & Lion's Mane?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pine Pollen & Lion's Mane with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Pine Pollen & Lion's Mane, from the product label.

Raw Forest Foods

See all Raw Forest Foods products
Name
RAW Forest Foods LLC
Street Address
11 Elmwood Ave, Suite 102
City
Burlington
State
VT
ZipCode
05402
Phone Number
(802) 349-1347
Web Address
Rawforestfoods.com
Pharmacist Counseling Corner

Pine Pollen & Lion's Mane by Raw Forest Foods: Common Questions

Does Pine Pollen & Lion's Mane by Raw Forest Foods interact with any medications?
Yes. Based on its ingredients, Pine Pollen & Lion's Mane has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pine Pollen & Lion's Mane contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lion's mane actually work for memory or focus?
The evidence we have is insufficient to rate it for cognitive function, cognitive impairment, or any of the other conditions it's marketed for. There just isn't enough reliable research yet to say whether it does.
What are the side effects I might notice?
Most common are stomach discomfort, nausea, and skin rash. Lion's mane is generally well tolerated overall, but long-term safety as a supplement hasn't been well studied.
Is it safe to use if I'm pregnant or breastfeeding?
No — there isn't enough safety data, so the guidance is to avoid it during pregnancy and breastfeeding. Talk with your doctor or pharmacist about your options.
What's the difference between the pine pollen and the lion's mane in here?
Lion's mane is a medicinal mushroom extract we have data on. Pine pollen is there for traditional use, but we don't hold interaction or effectiveness information for it.
Are there any fillers in this?
Yes — cellulose is listed as an inactive ingredient. It's a common filler used in capsules.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pine Pollen & Lion's Mane is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pine Pollen & Lion's Mane label
Sources

Sources & How We Checked

Pine Pollen & Lion's Mane's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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