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Dietary supplement

Potassium Chloride 365 mg Ingredients & Drug Interactions

by Nutricost

Potassium Chloride 365 mg label
See full label image
Powder Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Potassium Chloride 365 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Potassium Chloride 365 mg is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Potassium Chloride 365 mg by Nutricost

Ask about any prescription or over-the-counter medication and we check it for interactions with Potassium Chloride 365 mg by Nutricost — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Potassium Chloride 365 mg by Nutricost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: potassium, supplied as potassium chloride in a powder form, providing 365 mg per serving. There are no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Potassium product and its label doesn't state a use — see Potassium's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for this product in our records. Potassium supplements are commonly used to prevent or correct low potassium levels, but the evidence for specific health claims isn't in the information we have on file.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe, but supplements can cause dangerously high blood levels in some people — especially those with kidney disease. When taken by mouth, potassium is generally well-tolerated, though common side effects include abdominal pain, belching, diarrhea, flatulence, nausea, and vomiting.

Serious adverse effects (rare) linked to high potassium levels include irregular heartbeats, heart block, low blood pressure, and mental confusion; slow-release potassium tablets have also been associated with bleeding duodenal ulcers. During pregnancy, dietary potassium is appropriate, but use supplements only under medical guidance.

While breastfeeding, check with your doctor before using supplements — dietary potassium is fine, but the same caution applies to supplemental forms.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this supplement, double-check your medications with your doctor or pharmacist if you're on a potassium-sparing diuretic (water pill), ACE inhibitor, or ARB — all carry a Moderate risk of high blood potassium (hyperkalemia). The risk is especially serious if you have kidney problems.

No other medication interactions are documented in our data for this ingredient, but always confirm your full medication list with your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is for people whose doctor has identified low potassium and wants them to supplement — not for casual use. If you take a blood pressure medication (especially potassium-sparing diuretics, ACE inhibitors, or ARBs), or if you have kidney disease, you'll want to confirm with your doctor or pharmacist before adding this, because the interaction risk is real and can affect your heart rhythm.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Potassium Chloride 365 mg, straight from the product label.

Brand Nutricost
Barcode (UPC) 810014672878
Net contents 35 oz; 2.2 Pound(s); 1000 Gram(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 270725
Product type Mineral
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Potassium Chloride 365 mg by Nutricost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 Gram(s)
Maximum serving Sizes:
0.7 Gram(s)
Servings per container
1425
UPC/BARCODE
810014672878
IngredientAmount% DV
Potassium365 mg8%

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1/8 tsp (0.7 g) once daily or as directed by your healthcare professional.

Precautions

Warning: For healthy individuals 18 years and older.

Consult a healthcare professional prior to use if you are pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not use if safety seal is broken or missing.

Storage

Notice: Store in a cool, dry place.

Formula

Potassium Chloride 365 mg per serving

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Quality Guaranteed Nutricost

Formulation

Third Party Tested

Gluten-Free Product Non-GMO Product

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Potassium Chloride 365 mg by Nutricost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Potassium Chloride 365 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Potassium Chloride 365 mg by Nutricost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 Gram(s) Dosage formPowder Servings per container1425 Amounts shown are per serving.

Potassium

Interacts with
62 drugs
365 mg per serving Form: Potassium Chloride

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Potassium Chloride 365 mg by Nutricost Drug Interactions

Want to check YOUR meds against Potassium Chloride 365 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Potassium Chloride 365 mg interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Potassium Chloride 365 mg interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Potassium Chloride 365 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Potassium Chloride 365 mg, from the product label.

Nutricost

See all Nutricost products
Name
Nutricost
Street Address
351 E 1750 N
City
Vineyard
State
UT
ZipCode
84059
Phone Number
(866) 438-3694
Web Address
www.nutricost.com
Pharmacist Counseling Corner

Potassium Chloride 365 mg by Nutricost: Common Questions

Does Potassium Chloride 365 mg by Nutricost interact with any medications?
Yes. Based on its ingredients, Potassium Chloride 365 mg has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Potassium Chloride 365 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood pressure medication?
It depends on which one. If you take a potassium-sparing diuretic, ACE inhibitor, or ARB, combining this supplement with those drugs raises your blood potassium to a dangerous level — that's a Moderate-severity interaction. Talk to your doctor or pharmacist about your specific medication before starting this.
Is potassium supplement safe if I have kidney disease?
No — kidney disease is a major caution. Your kidneys control how much potassium your body keeps or lets go, so if kidney function is impaired, a supplement can cause dangerously high blood levels. This is something to discuss with your doctor before considering any potassium supplement.
What are the side effects I might notice?
The common ones are stomach-related: abdominal pain, belching, diarrhea, flatulence, nausea, and vomiting. Rare but serious effects from too much blood potassium include irregular heartbeats, heart block, low blood pressure, and confusion — these need urgent medical attention.
Is it safe to use this while pregnant or breastfeeding?
Dietary potassium is fine during both pregnancy and breastfeeding, but supplements should only be used under medical guidance. Talk with your doctor before taking this supplement in either situation — they'll know whether you need it and in what dose.
Why is this powder instead of a tablet?
The facts on file don't explain the choice of form. If you have concerns about powder versus tablet, your pharmacist can help you pick the form that works best for you.
Do I need a potassium supplement?
That's something only your doctor can decide based on your blood work and health history. Supplements aren't for everyone, and taking one without medical guidance — especially if you have kidney issues or take certain blood pressure drugs — can be risky. Check with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Potassium Chloride 365 mg label
Go deeper

The Full Monographs Behind Potassium Chloride 365 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Potassium Chloride 365 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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