Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Potassium Gluconate 595 mg Ingredients & Drug Interactions

by Mason Natural

Potassium Gluconate 595 mg label
See full label image
Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Potassium Gluconate 595 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Potassium Gluconate 595 mg is a dietary supplement by Mason Natural with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Potassium Gluconate 595 mg by Mason Natural

Ask about any prescription or over-the-counter medication and we check it for interactions with Potassium Gluconate 595 mg by Mason Natural — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Potassium Gluconate 595 mg by Mason Natural

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: potassium, supplied as potassium gluconate at 595 mg per tablet. Potassium is an essential mineral that helps your heart, muscles, and nerves work properly and helps regulate fluid balance and blood pressure.

The tablet also contains inactive ingredients used to hold it together and make it easier to swallow: microcrystalline cellulose, croscarmellose sodium, stearic acid, vegetable magnesium stearate, and silicon dioxide.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support fluid balance.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The product facts we hold do not include effectiveness ratings for potassium gluconate, so we cannot tell you from our data whether this supplement works for its intended purpose. If you're considering it to address a specific health concern — especially low blood potassium — talk with your doctor or pharmacist first; they can confirm whether supplementation is right for you and what dose would be appropriate.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe for most people, but supplements can cause dangerously high blood levels in some people, especially those with kidney disease. Oral potassium is generally well tolerated, though some people experience stomach upset — abdominal pain, belching, diarrhea, flatulence, nausea, or vomiting.

Serious side effects from high potassium levels are rare but can include irregular heartbeat, low blood pressure, heart block, or mental confusion. During pregnancy, potassium from food is appropriate, but use supplements only under medical guidance.

If you're breastfeeding, the facts on file do not provide enough safety data for potassium supplements — talk with your doctor or pharmacist to decide what's right for you. People with kidney disease should be especially cautious, as their kidneys may not clear excess potassium safely.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take any potassium-sparing diuretics (such as spironolactone), ACE inhibitors (such as lisinopril), or angiotensin receptor blockers (such as losartan). All three increase your potassium levels, and adding a supplement can raise them to unsafe levels.

No interactions are documented for the ingredients we could check beyond these three drug classes.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If your doctor has told you that you're low in potassium and you're not taking a blood pressure medication that affects potassium levels, this supplement may be an option — but confirm the dose and timing with your own doctor first. If you take any diuretic, ACE inhibitor, or ARB, you'll need to check directly with your doctor or pharmacist before starting this product, because the risk of high blood potassium is real.

Kidney problems are also a red flag — bring them up before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Potassium Gluconate 595 mg, straight from the product label.

Brand Mason Natural
Barcode (UPC) 311845061812
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 244832
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Potassium Gluconate 595 mg by Mason Natural, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
311845061812
IngredientAmount% DV
Potassium99 mg2%

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Vegetable Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Mason Guarantee Laboratory Tested cGMP Certified Good Manufacturing Practice

General Statements

Certified N Mason natural Est. 1967

Please recycle

Formulation

May support fluid balance

Guaranteed no added: Sugar, starch, yeast, soy, corn, wheat, dairy, gluten, fish, tree nuts, peanuts, egg, fragrance, artificial colors or flavors, preservatives, animal products, crustacean shellfish. Sodium free.

Gluten free Soy free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults - Take one tablet daily, preferably with food and a full glass of water, as a dietary supplement. Swallow tablet without crushing or chewing.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: If you are pregnant, nursing, taking any medications or have any medical condition, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur.

Keep out of reach of children.

Tamper-Evident Seal: Do not use product if seal appears tampered.

Storage

Store in a dry place under controlled room temperature: 20 degrees - 25 degrees C (68 degrees - 77 degrees F).

Brand IP Statement(s)

Mason Natural is a registered trademark and does not refer to any product or ingredient claim.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Potassium Gluconate 595 mg by Mason Natural label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Potassium Gluconate 595 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Potassium Gluconate 595 mg by Mason Natural

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Potassium

Interacts with
62 drugs
99 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Potassium Gluconate 595 mg by Mason Natural Drug Interactions

Want to check YOUR meds against Potassium Gluconate 595 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Potassium Gluconate 595 mg interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Potassium Gluconate 595 mg interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Potassium Gluconate 595 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Potassium Gluconate 595 mg, from the product label.

Mason Natural

See all Mason Natural products
Name
Mason Vitamins, Inc.
City
Miami Lakes
State
FL
ZipCode
33014
Phone Number
1-888-860-5376
Web Address
www.MasonVitamins.com
Pharmacist Counseling Corner

Potassium Gluconate 595 mg by Mason Natural: Common Questions

Does Potassium Gluconate 595 mg by Mason Natural interact with any medications?
Yes. Based on its ingredients, Potassium Gluconate 595 mg has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Potassium Gluconate 595 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have kidney disease?
No — talk with your doctor first. The facts advise caution in people with kidney disease, because damaged kidneys may not clear excess potassium safely, and high blood potassium can cause serious heart problems. Your doctor needs to know about your kidney function before you start any potassium supplement.
What side effects might I notice?
Most people tolerate oral potassium well, but you might notice stomach upset — nausea, vomiting, abdominal pain, diarrhea, belching, or gas. Serious side effects (rare) from high potassium levels include irregular heartbeat, low blood pressure, or mental confusion. If you notice any of those, stop and contact your doctor right away.
Is this safe to take during pregnancy or while breastfeeding?
Potassium from food is fine in pregnancy. For supplements, the data notes they should be used only under medical guidance. If you're breastfeeding, there isn't enough safety data on file to say either way — talk with your doctor before starting.
Why does this interact with blood pressure medications?
Many blood pressure drugs (ACE inhibitors, ARBs, and potassium-sparing diuretics) work by affecting how your kidneys handle potassium. On their own, that helps your blood pressure — but when you add a potassium supplement, your blood potassium can climb too high, which stresses your heart.
How much potassium do I need?
The product facts don't address dosing. Your doctor or pharmacist can tell you how much is right for you based on your diet, kidneys, medications, and health. Don't guess on this one — potassium balance is serious.
Can I just get potassium from food instead?
Yes — potassium from food (like bananas, potatoes, spinach, and beans) is safe for most people and usually doesn't cause the high blood potassium levels that supplements can. If your doctor thinks you need supplementation, they'll tell you. Otherwise, food is the way to go.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Potassium Gluconate 595 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Potassium Gluconate 595 mg label
Go deeper

The Full Monographs Behind Potassium Gluconate 595 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Potassium Gluconate 595 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team