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Dietary supplement

Premium Apple Cider Vinegar Detox Ingredients & Drug Interactions

by Nobi Nutrition

Premium Apple Cider Vinegar Detox label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Premium Apple Cider Vinegar Detox against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Premium Apple Cider Vinegar Detox is a dietary supplement by Nobi Nutrition with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 162 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Premium Apple Cider Vinegar Detox by Nobi Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Premium Apple Cider Vinegar Detox by Nobi Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Premium Apple Cider Vinegar Detox by Nobi Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: apple cider vinegar. It also includes two inactive ingredients—cellulose and L-leucine—which are a filler and a capsule additive.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Apple Cider Vinegar's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight loss and detoxification support.
  • We looked for evidence on: Obesity, metabolic health, digestive wellness.
  • The closest evidence on file: Apple Cider Vinegar is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence we hold doesn't establish that apple cider vinegar works for any of the uses listed in this product—including acne, athletic performance, cognitive function, dental plaque, depression, or atopic dermatitis (eczema). For each of these, the data shows insufficient reliable evidence to say whether it helps.

The evidence, ingredient by ingredient Apple Cider Vinegar

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Apple cider vinegar in food amounts—the kind you'd use in salad dressing or a splash in water—is generally well tolerated. However, in larger supplement doses or undiluted, especially over the long term, safety data is limited and concerns arise.

Serious but rare side effects from long-term high-dose use include low potassium, high renin levels (a kidney hormone), and bone loss. If you apply it to your skin, it can cause chemical burns and irritation.

The safety notes advise that food amounts are likely fine, but large medicinal or unpasteurized doses should only be used with your doctor's approval.

Side effects, ingredient by ingredient Apple Cider Vinegar

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Apple Cider Vinegar.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 162 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on digoxin (a heart medication), diuretics (water pills), insulin, or other diabetes medications. Apple cider vinegar can raise the risk of low potassium or low blood sugar when combined with these drugs.

No interactions are documented for other medication types in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Apple cider vinegar in everyday food amounts is generally well tolerated, but this supplement form raises concerns about long-term safety and interactions with heart, blood pressure, and diabetes medications. If you take digoxin, diuretics, insulin, or diabetes drugs, talk with your doctor or pharmacist before starting.

The effectiveness evidence for the listed uses isn't established, so weigh that against the interaction risks for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Premium Apple Cider Vinegar Detox, straight from the product label.

Brand Nobi Nutrition
Barcode (UPC) B07Q8SZ5VP
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246785
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Premium Apple Cider Vinegar Detox by Nobi Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veggie Capsule(s)
Maximum serving Sizes:
2 Veggie Capsule(s)
Servings per container
30
UPC/BARCODE
B07Q8SZ5VP
IngredientAmount% DV
Apple Cider Vinegar1300 mg--

Other ingredients: Cellulose, L-Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) capsules once a day with food or as directed by your healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

General Statements

100% 60 Day Money Back Guarantee

Seals/Symbols

Formulated in the U.S.A. GMP Sourced From a GMP Certified Facility

Formulation

Women's Fat Burner Weight Loss Detoxification Heart Healthy

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Premium Apple Cider Vinegar Detox by Nobi Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Premium Apple Cider Vinegar Detox label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Premium Apple Cider Vinegar Detox by Nobi Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Apple Cider Vinegar

Interacts with
162 drugs
1300 mg per serving

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Other (inactive) ingredients: Cellulose, L-Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Premium Apple Cider Vinegar Detox by Nobi Nutrition Drug Interactions

Want to check YOUR meds against Premium Apple Cider Vinegar Detox?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
162Drugs
89 Moderate 73 Minor

Ingredients driving the most interactions

Apple Cider Vinegar 162

Individual Drug Interactions

The ingredients in Premium Apple Cider Vinegar Detox interact with 162 drugs. Click any drug to see the details.

1 of the 1 ingredient in Premium Apple Cider Vinegar Detox interact with drugs. Each result below shows which ingredient is responsible. Apple Cider Vinegar

Each ingredient & the kinds of drugs it affects

For each ingredient in Premium Apple Cider Vinegar Detox with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Premium Apple Cider Vinegar Detox, from the product label.

Nobi Nutrition

See all Nobi Nutrition products
Name
Nobi Nutrition
Street Address
427 N Tatnail Street
City
Wilmington
State
DE
ZipCode
19801
Pharmacist Counseling Corner

Premium Apple Cider Vinegar Detox by Nobi Nutrition: Common Questions

Does Premium Apple Cider Vinegar Detox by Nobi Nutrition interact with any medications?
Yes. Based on its ingredients, Premium Apple Cider Vinegar Detox has a known interaction with 162 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Premium Apple Cider Vinegar Detox contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is apple cider vinegar safe in regular food amounts?
Yes—in the amounts you'd use in cooking or a splash in water, apple cider vinegar is generally well tolerated. The safety concerns arise with larger supplement doses, especially over the long term or if it's undiluted.
Can I take this if I'm on a water pill for blood pressure?
Not without talking to your doctor or pharmacist first. Apple cider vinegar may lower your potassium level, and when combined with diuretics (water pills), that risk increases. Your healthcare provider needs to know about both to decide if it's safe for you.
Will this help my acne or eczema?
The evidence we have doesn't establish that apple cider vinegar works for acne or atopic dermatitis (eczema). The research is insufficient to say whether it helps with either condition.
What happens if I apply apple cider vinegar to my skin?
Topical application can cause chemical burns, skin irritation, and erosion. Cases have been reported after just a few days of use, so it's not recommended as a topical treatment.
Is it safe during pregnancy or while breastfeeding?
The safety data on file doesn't cover pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you in those situations.
Can this help me lose weight or detoxify my body?
The product facts don't include effectiveness data for weight loss or detoxification. The uses we have evidence for—or lack thereof—are acne, athletic performance, cognitive function, dental plaque, depression, and eczema, and the evidence doesn't support most of them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Premium Apple Cider Vinegar Detox is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Premium Apple Cider Vinegar Detox label
Go deeper

The Full Monographs Behind Premium Apple Cider Vinegar Detox’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph →
Sources

Sources & How We Checked

Premium Apple Cider Vinegar Detox's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Apple Cider Vinegar 11 references
  1. Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
  3. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
  4. Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
  5. Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
  6. Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
  7. Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
  8. Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
  9. Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
  10. Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
  11. Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro

See these in context on the Apple Cider Vinegar monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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