Prenatal Gummies Ingredients & Drug Interactions
by HappyMama
What is this page for?
First and foremost: checking Prenatal Gummies against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Prenatal Gummies is a dietary supplement by HappyMama with 5 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 995 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D3, Omega-3 Fatty Acids, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Prenatal Gummies by HappyMama
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Prenatal Gummies by HappyMama
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
HappyMama's Prenatal Gummies contain 5 active ingredients: eicosapentaenoic acid and docosahexaenoic acid (omega-3 fatty acids important during pregnancy), sodium, vitamin D3, and choline. These are combined with inactive ingredients — cane sugar, tapioca syrup, gelatin, pectin, citric acid, fumaric acid, natural flavors, and added colors — that give the gummy its form and taste.
Does it work?
Not established
Vitamin D3 in this product is effective for certain bone and mineral disorders — familial hypophosphatemia, osteomalacia (soft bones), renal osteodystrophy, rickets, and hypoparathyroidism. For the other active ingredients, the evidence we hold does not establish effectiveness for any particular condition; choline, for example, is rated insufficient evidence for age-related cognitive decline, Alzheimer's disease, and other uses, and omega-3 fatty acids' effectiveness for pregnancy outcomes is not rated in our data.
How safe is it?
Well-documented data
Vitamin D3 is generally well tolerated at recommended doses, though very high doses over time can cause toxicity with symptoms of high blood calcium. Choline is well tolerated in appropriate amounts, but doses above 3.5 grams daily may cause fishy body odor, nausea, vomiting, or diarrhea.
Sodium is essential in small amounts, but too much is linked to high blood pressure and heart strain — normal dietary sodium is fine, but avoid sodium supplements or very high intake without medical advice. For pregnancy and lactation: vitamin D3 is rated likely safe during pregnancy and lactation at recommended doses, choline is rated likely safe for both, and sodium is rated likely safe for pregnancy but possibly unsafe for lactation in some cases.
There is insufficient data on file for eicosapentaenoic acid and docosahexaenoic acid during pregnancy and lactation — talk with your doctor or pharmacist for personalized guidance.
Meds to double-check
Moderate interaction found
Before taking this gummy, check with your doctor or pharmacist if you take lithium, blood pressure medications (antihypertensives), corticosteroids, heart rhythm drugs (verapamil, diltiazem, digoxin), the HIV medication didanosine, the cholesterol drug atorvastatin, thiazide diuretics, or atropine. Sodium content can alter lithium levels and blood pressure control; vitamin D3 can raise blood calcium and interfere with heart medications.
These are Moderate-severity interactions that need individual review.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
HappyMama's Prenatal Gummies may be appropriate for pregnant or nursing people who need prenatal nutrition and want the omega-3 fatty acids, choline, and vitamin D it provides. If you take any medication for blood pressure, heart rhythm, lithium, HIV, or corticosteroids, or if you take a separate vitamin D or sodium supplement, you should check with your doctor or pharmacist before starting this product.
The interaction risks are real but manageable with the right oversight.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Prenatal Gummies, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Prenatal Gummies by HappyMama, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 40 Calorie(s) | -- |
| Total Carbohydrates | 9 Gram(s) | -- |
| Sugar | 6 Gram(s) | -- |
| Eicosapentaenoic Acid | 22 mg | -- |
| Docosahexaenoic Acid | 110 mg | -- |
| Sodium | 25 mg | -- |
| Total Fat | 0.5 Gram(s) | -- |
| Vitamin D3 | 600 IU | 150% |
| Choline | 45 mg | -- |
| Cholesterol | 5 mg | -- |
| Omega-3 Fatty Acids | 150 mg | -- |
Other ingredients: Cane Sugar, Tapioca Syrup, Gelatin, Pectin, Citric Acid, Fumaric Acid, Natural flavors, Colors Added
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
DHA, Omega-3's, Choline + Vitamin D
110 mg DHA 150 mg Omega-3's 45 mg Choline 150% DV Vitamin D3
These supplements come in a tasty mix of berry, lemon and orange flavors. With every serving, a blend of Omegas, DHA, Choline and Vitamin D provides nutrients needed to help support baby's healthy development.
Suitable for breastfeeding moms
Contains: Fish (Tuna).
General Statements
Lemon+Berry+Orange
Flavored with other natural flavors
Specially formulated, flavorful and downright fun, our prenatal gummies are an easy way to complement your prenatal Vitamin.
The most accurate information is always on the label on the actual product. We periodically update our labels, and the website does not necessarily get updated at the same time. The values on the website are intended to be a general guide to consumers. For the most accurate information, please refer to the product itself.
This product uses high quality, purified Fish Oil that has been tested for Mercury and PCBs.
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
2017 Nurture, Inc. All rights reserved.
Precautions
Contains: Fish (Tuna).
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Prenatal Gummies by HappyMama label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Prenatal Gummies by HappyMama
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Gummy(ies) Dosage formGummy Or Jelly Servings per container27 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsVitamin D3
Interacts with715 drugs
Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...
Vitamin D3 monograph & interactionsCholine
Interacts with16 drugs
Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...
Choline monograph & interactionsOmega-3 Fatty Acids
Interacts with375 drugs
DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...
Omega-3 Fatty Acids monograph & interactions- › Eicosapentaenoic Acid
- › Docosahexaenoic Acid
Other (inactive) ingredients: Cane Sugar, Tapioca Syrup, Gelatin, Pectin, Citric Acid, Fumaric Acid, Natural flavors, Colors Added. These complete the product’s ingredient list but are not active constituents.
Prenatal Gummies by HappyMama Drug Interactions
HelloPharmacist Interaction Report
HappyMama's Prenatal Gummies contain several ingredients with documented medication interactions.
The most serious concerns come through sodium, vitamin D3, and choline — sodium poses the biggest single risk, as high intake can dangerously alter lithium levels, reduce blood pressure medication effectiveness, and raise the risk of high blood sodium (hypernatremia) when combined with certain corticosteroids, blood pressure drugs, or the HIV medication didanosine.
Read the full breakdown — every affected drug type, severity by severity
Vitamin D3 interacts with heart rhythm medications (verapamil, diltiazem, digoxin) through its potential to raise blood calcium to unsafe levels, and also with thiazide diuretics, the cholesterol drug atorvastatin, and the psoriasis medication calcipotriene. Choline has one documented interaction: it may theoretically reduce the effects of atropine.
We could not check eicosapentaenoic acid or docosahexaenoic acid — interaction data is not held for these ingredients.
Although the sodium and vitamin D3 doses in a prenatal gummy are typically modest, the risk rises if you're also taking other sodium-containing products, high-dose vitamin D supplements elsewhere, or any of the drugs listed. Altogether, these interactions span 837 individual medications.
Check your exact medications with the tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Prenatal Gummies?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Prenatal Gummies interact with 995 drugs. Click any drug to see the details.
4 of the 5 ingredients in Prenatal Gummies interact with drugs. Each result below shows which ingredient is responsible. Vitamin D3 Omega-3 Fatty Acids Sodium Choline
Ibuprofen LysineNeoProfen
How Ibuprofen Lysine interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Ibuprofen Lysine interactionIbuprofen, AcetaminophenAdvil Dual Action
How Ibuprofen, Acetaminophen interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Ibuprofen, Acetaminophen interactionIbuprofen, HydrocodoneIbucodone
How Ibuprofen, Hydrocodone interacts with Prenatal Gummies — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Ibuprofen, Hydrocodone interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Ibuprofen, Hydrocodone interactionIbuprofen, OxycodoneCombunox
How Ibuprofen, Oxycodone interacts with Prenatal Gummies — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Ibuprofen, Oxycodone interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Ibuprofen, Oxycodone interactionIbuprofen, PseudoephedrineDristan
How Ibuprofen, Pseudoephedrine interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Ibuprofen, Pseudoephedrine interactionIcosapent Ethyl (prescription Drug)Vascepa
How Icosapent Ethyl (prescription Drug) interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Icosapent Ethyl (prescription Drug) interactionIloprostAurlumyn, Ventavis
How Iloprost interacts with Prenatal Gummies — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Iloprost interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Iloprost interactionIndapamideLozide, Lozol
How Indapamide interacts with Prenatal Gummies — through 3 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Indapamide interactionVitamin D3Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D3 + Indapamide interactionOmega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Indapamide interactionInhaled InsulinExubera
How Inhaled Insulin interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Inhaled Insulin interactionInotersenTegsedi
How Inotersen interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Inotersen interactionInsulinNovoRapid Insulin
How Insulin interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin interactionInsulin (bovine)Hypurin Bovine Neutral
How Insulin (bovine) interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin (bovine) interactionInsulin (human)Afrezza, Novolin 70/30, Novolin L, Novolin N, Novolin R
How Insulin (human) interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin (human) interactionInsulin (pork)Hypurin Porcine Neutral, Lente Iletin II, NPH Iletin, NPH Iletin II, Pork Actrapid, Regular Iletin +1 more
How Insulin (pork) interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin (pork) interactionInsulin (rdna)Actrapid, Humalog, Humalog Mix 75/25, Humulin 50/50, Humulin 70/30, Humulin L +8 more
How Insulin (rdna) interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin (rdna) interactionInsulin AspartFiasp
How Insulin Aspart interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Aspart interactionInsulin Aspart, Insulin DegludecRyzodeg 70/30
How Insulin Aspart, Insulin Degludec interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Aspart, Insulin Degludec interactionInsulin DegludecTresiba
How Insulin Degludec interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Degludec interactionInsulin Degludec, LiraglutideXultophy 100/3.6
How Insulin Degludec, Liraglutide interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Degludec, Liraglutide interactionInsulin GlargineBasaglar, Lusduna, Semglee
How Insulin Glargine interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Glargine interactionInsulin Glargine (rdna)Lantus
How Insulin Glargine (rdna) interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Glargine (rdna) interactionInsulin Glargine RecombinantToujeo Solostar
How Insulin Glargine Recombinant interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Glargine Recombinant interactionInsulin Glargine, LixisenatideSoliqua 100/33
How Insulin Glargine, Lixisenatide interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Glargine, Lixisenatide interactionInsulin Glulisine (rdna)Apidra
How Insulin Glulisine (rdna) interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Glulisine (rdna) interactionInsulin Human, Sodium ChlorideMyxredlin
How Insulin Human, Sodium Chloride interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Human, Sodium Chloride interactionInsulin LisproAdmelog, Admelog Solostar
How Insulin Lispro interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Lispro interactionInsulin Lispro RecombinantHumalog Kwikpen
How Insulin Lispro Recombinant interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Lispro Recombinant interactionInsulin Lispro-aabcLyumjev
How Insulin Lispro-aabc interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Lispro-aabc interactionInsulin DetermirLevemir
How Insulin Determir interacts with Prenatal Gummies — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Insulin Determir interactionIrbesartanAprovel, Avapro
How Irbesartan interacts with Prenatal Gummies — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Irbesartan interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Irbesartan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Prenatal Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin D3
Aluminum
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.
Atorvastatin (Lipitor)
Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.
Calcipotriene (Dovonex)
Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.
Digoxin (Lanoxin)
Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.
Diltiazem (Cardizem, Others)
Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.
Thiazide Diuretics
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.
Verapamil (Calan, Others)
Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.
Omega-3 Fatty Acids
Anticoagulant/Antiplatelet Drugs
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.
Antidiabetes Drugs
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.
Antihypertensive Drugs
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Choline
Atropine
Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.
Brand information
Manufacturer and brand details for Prenatal Gummies, from the product label.
Prenatal Gummies by HappyMama: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Prenatal Gummies’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographVitamin D
Interacts with 715 drugsVitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...
Read the full Vitamin D monograph → Herb & supplement monographCholine
Interacts with 16 drugsCholine is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...
Read the full Choline monograph → Herb & supplement monographDocosahexaenoic Acid (dha)
Interacts with 375 drugsDHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...
Read the full Docosahexaenoic Acid (dha) monograph →Sources & How We Checked
Prenatal Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 127 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
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Vitamin D 26 references
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Choline 14 references
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Docosahexaenoic Acid (dha) 49 references
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See these in context on the Docosahexaenoic Acid (dha) monograph →
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