Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

ProBiota Immune Ingredients & Drug Interactions

by Seeking Health

ProBiota Immune label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ProBiota Immune against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ProBiota Immune is a dietary supplement by Seeking Health with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-Glucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against ProBiota Immune by Seeking Health

Ask about any prescription or over-the-counter medication and we check it for interactions with ProBiota Immune by Seeking Health — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of ProBiota Immune by Seeking Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Prebiotic Blend” is a proprietary blend — the label gives one combined amount (550 mg) without saying how much of each component you get.

ProBiota Immune contains 2 active ingredients: a prebiotic blend and beta-glucan. Prebiotics are non-digestible food components that feed beneficial bacteria in your gut.

Beta-glucan is a type of soluble fiber derived from sources like yeast and mushrooms; it's known for its effects on cholesterol and heart health. The capsule also contains vegetarian-friendly inactive ingredients: cellulose, L-leucine, and the capsule shell itself.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune support.
  • We looked for evidence on: Exercise-induced respiratory infections, Lower respiratory tract infections, Critical illness (trauma), Wound healing, infection prevention, immune function.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Lower respiratory tract infections, Wound healing, Critical illness (trauma).

Beta-glucan in this product is rated likely effective for improving cholesterol levels (dyslipidemia) and supporting heart health in coronary heart disease. Research supports its use for these purposes.

We hold no effectiveness data on the prebiotic blend or galacto-oligosaccharides in our current monographs, so we can't speak to how well they work in this formulation.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated. However, concentrated supplements like this one lack extensive safety data, so caution is advised if you're new to them.

Topically (in creams), beta-glucans have caused mild, self-limiting skin reactions and contact dermatitis in clinical trials, though oral supplements haven't shown this issue. In one trial of children receiving very high doses, one patient developed temporary liver enzyme elevations.

There isn't enough research on supplement doses during breastfeeding to know what's safe, so talk with your doctor or pharmacist if you're nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking ProBiota Immune, check with your doctor or pharmacist if you take immunosuppressants (drugs that weaken immunity after transplant or for autoimmune disease) — beta-glucans may reduce their effectiveness. Also check if you're on blood pressure medications (antihypertensives), since beta-glucans may lower blood pressure further.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

ProBiota Immune may be worth considering if you're interested in prebiotic fiber and beta-glucan's documented benefits for cholesterol and heart health. If you take medications to suppress your immune system or control blood pressure, you'll want to check this product with your doctor or pharmacist first — the beta-glucan could interfere with how those drugs work.

Start a conversation with your own healthcare provider to see if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ProBiota Immune, straight from the product label.

Brand Seeking Health
Barcode (UPC) 810007521039
Net contents 60 Vegetarian Capsules
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 211093
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ProBiota Immune by Seeking Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
810007521039
IngredientAmount% DV
Prebiotic Blend550 mg--
Galacto-oligosaccharides0 NP--
Beta-Glucan0 NP--

Other ingredients: Vegetarian Capsule, L-Leucine, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule twice daily or as directed by your healthcare professional.

Precautions

Children and pregnant or lactating women should consult their healthcare professional prior to use.

Children and pregnant or lactating women should consult their healthcare professional prior to use.

Do not use if shrinkwrap is broken or missing.

Keep out of reach of children.

Storage

Storage: Store in a cool, dry place below 85(0)F away from direct light. Do not freeze.

Formulation

Does Not Contain: eggs, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.

General Statements

ProBiota Immune meets or exceeds cGMP Quality Standards. Targeted Support

FDA Statement of Identity

Prebiotic Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ProBiota Immune by Seeking Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ProBiota Immune label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ProBiota Immune by Seeking Health

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Prebiotic Blend

550 mg per serving

Other (inactive) ingredients: Vegetarian Capsule, L-Leucine, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

ProBiota Immune by Seeking Health Drug Interactions

Want to check YOUR meds against ProBiota Immune?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Beta-Glucan 293

Individual Drug Interactions

The ingredients in ProBiota Immune interact with 293 drugs. Click any drug to see the details.

1 of the 2 ingredients in ProBiota Immune interact with drugs. Each result below shows which ingredient is responsible. Beta-Glucan

Each ingredient & the kinds of drugs it affects

For each ingredient in ProBiota Immune with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Beta-Glucan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ProBiota Immune, from the product label.

Seeking Health

See all Seeking Health products
Name
Seeking Health
Street Address
3140 Mercer Ave
City
Bellingham
State
WA
ZipCode
98225
Phone Number
(800) 547-9812
Web Address
www.seekinghealth.com
Pharmacist Counseling Corner

ProBiota Immune by Seeking Health: Common Questions

Does ProBiota Immune by Seeking Health interact with any medications?
Yes. Based on its ingredients, ProBiota Immune has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ProBiota Immune contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my immune system?
We hold effectiveness data for beta-glucan's role in cholesterol and heart health, but we don't have evidence in our data that this product boosts immunity overall. Prebiotics and beta-glucan may support gut health, which plays a role in immunity, but we can't claim specific immune benefits from the data we have.
What's in the prebiotic blend?
The product contains a prebiotic blend, but the specific breakdown of which prebiotics are in it isn't listed in the product facts we have. You may find more detail on the manufacturer's website or the product label itself.
Is it safe if I'm breastfeeding?
There isn't enough research on concentrated supplement doses of beta-glucan during breastfeeding to know what's safe. Talk with your doctor or pharmacist about whether this product is right for you if you're nursing — they can give you personalized guidance.
Can beta-glucan cause side effects?
Beta-glucans are generally well tolerated when taken by mouth. In one trial, one patient on a very high dose developed temporary liver enzyme changes. Topical beta-glucan creams have caused mild, self-resolving skin reactions in some people, but that's not relevant for this oral capsule.
Why does the capsule contain L-leucine?
L-leucine is an amino acid used as an inactive ingredient in the capsule — it helps with things like flow and separation of the powder inside so it fills evenly. It's not an active therapeutic ingredient in this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ProBiota Immune is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ProBiota Immune label
Go deeper

The Full Monographs Behind ProBiota Immune’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

ProBiota Immune's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team