Probiotic 40 Billion CFU Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Probiotic 40 Billion CFU against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Probiotic 40 Billion CFU is a dietary supplement by Evlution Nutrition with 4 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, ProDURA. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Probiotic 40 Billion CFU by Evlution Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic 40 Billion CFU by Evlution Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Probiotic 40 Billion CFU by Evlution Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 4 active probiotic ingredients: two Lactobacillus species (L. plantarum and L. acidophilus), Bifidobacterium animalis lactis, and Bacillus coagulans (marketed as ProDURA). Together they deliver 40 billion colony-forming units (CFU)—live microorganisms meant to support your gut.
The inactive ingredients are microcrystalline cellulose, hypromellose, magnesium stearate, and silica, which are common capsule fillers and binders.
Does it work?
Moderate evidence
For Lactobacillus acidophilus, the evidence is "possibly effective" for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. For Bacillus coagulans (ProDURA), it's "possibly effective" for constipation and IBS.
For other conditions listed in the research—like acute respiratory distress syndrome or athletic performance—the data we hold either don't show clear benefit or aren't established enough to rate. Your own results will depend on your specific condition and how your body responds.
How safe is it?
Well-documented data
Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Bacillus coagulans is also generally well tolerated in healthy adults, though product quality and safety evidence vary.
Both probiotic ingredients are live microorganisms, so there is a theoretical concern—mainly in severely ill or immunocompromised patients—that they could cause infection if they spread beyond the gut. In healthy people with normal immune systems, this risk is very low.
Uncommon oral side effects from probiotics include stomach discomfort, bloating, gas, diarrhea, and nausea; a small number of trial participants taking a probiotic blend experienced rash and itching, though it's unclear whether L. acidophilus was responsible. Talk with your doctor or pharmacist before starting, especially if you have a weakened immune system, have central venous catheters, or are critically ill.
Meds to double-check
Moderate interaction found
Antibiotic drugs are the main medication type to watch—they may reduce the effectiveness of the live cultures in this product if taken at the same time. Your doctor or pharmacist can help you space out doses to avoid this interaction.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is built for gut support—most likely for IBS or diarrhea linked to antibiotics or other causes. If you're in good health and not on antibiotics, probiotics are generally well tolerated.
However, if you take antibiotic medications or have a weakened immune system, check with your doctor or pharmacist first before adding this product. Run your full medication list through our interaction checker on this page.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Probiotic 40 Billion CFU, straight from the product label.
| Brand | Evlution Nutrition |
|---|---|
| Barcode (UPC) | 818901020627 |
| Net contents | 60 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 24, 2024 |
| DSLD ID | 302135 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Probiotic 40 Billion CFU by Evlution Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0 NP | -- |
| Lactobacillus plantarum | 0 NP | -- |
| Lactobacillus acidophilus | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| ProDURA | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Hypromellose, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Evlution Nutrition Ultra Pure Probiotic key benefits: 40 Billion CFU Healthy bacteria replenishment
Formulation
Digestion support Immune health support
Non Gmo ingredients Vegetarian/Gluten free
Vegetarian/Gluten free
High potency Supports immune health Balanced digestive system Digestive and immune support Clinically validated strains Supports digestive and immune health Supports replenishment of healthy bacteria
Minimum potency of 40 billion CFU at time of production.
This product is made in the USA, has been distributed and manufactured by a (GMP) registered facility and contains ingredients of domestic and international origin.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take 1 serving (2 capsules) daily or use as directed by a physician or licensed nutritionist.
Precautions
Warning: Not for use by those with pre-existing medical conditions; those taking any medications or those under the age of 18.
Warning: Not for use by those with pre-existing medical conditions; those taking any medications or those under the age of 18. Keep out of reach of children and pets.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Instagram Facebook Twitter @EVLSports #EVL
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
ProDURA is a trademark of UAS Laboratories LLC and used under license.
Storage
Keep product under recommended storage conditions to ensure probiotic potency through date on bottle.
Seals/Symbols
Made in the USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Probiotic 40 Billion CFU by Evlution Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Probiotic 40 Billion CFU by Evlution Nutrition
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Lactobacillus plantarum
- › Lactobacillus acidophilus
- › Bifidobacterium animalis lactis
- › ProDURA
Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Probiotic 40 Billion CFU by Evlution Nutrition Drug Interactions
HelloPharmacist Interaction Report
Probiotic 40 Billion CFU by Evlution Nutrition contains two checked ingredients—Lactobacillus acidophilus and Bacillus coagulans (ProDURA)—that both interact with antibiotic drugs.
The most serious concern is Moderate severity: taking this probiotic with antibiotics at the same time may reduce how well the probiotic works, because the antibiotics can kill the live organisms in the product. Altogether, these interactions span 182 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Both ingredients carry the same antibiotic interaction. The live and active cultures in this product are sensitive to antibiotics, so if you're on antibiotic therapy, you'll want to separate when you take them—your doctor or pharmacist can advise you on timing.
We could not check two other ingredients in the blend: Lactobacillus plantarum and Bifidobacterium animalis lactis. Use the medication checker below to see if any of your prescriptions fall into the antibiotic category, and talk with your doctor or pharmacist before combining this product with your current medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Probiotic 40 Billion CFU?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Probiotic 40 Billion CFU interact with 182 drugs. Click any drug to see the details.
2 of the 4 ingredients in Probiotic 40 Billion CFU interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus ProDURA
RifaximinXifaxan
How Rifaximin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Rifaximin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Rifaximin interactionSecnidazoleSolosec
How Secnidazole interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Secnidazole interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Secnidazole interactionSparfloxacinZagam
How Sparfloxacin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sparfloxacin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sparfloxacin interactionSpectinomycinTrobicin
How Spectinomycin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Spectinomycin interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Spectinomycin interactionStreptomycinStreptomycin
How Streptomycin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Streptomycin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Streptomycin interactionSulbactam, DurlobactamXacduro
How Sulbactam, Durlobactam interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulbactam, Durlobactam interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulbactam, Durlobactam interactionSulfadiazineSulfadiazine
How Sulfadiazine interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfadiazine interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfadiazine interactionSulfadiazine, Sulfamerazine, SulfamethazineTerfonyl, Triple Sulfoid
How Sulfadiazine, Sulfamerazine, Sulfamethazine interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfadiazine, Sulfamerazine, Sulfamethazine interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfadiazine, Sulfamerazine, Sulfamethazine interactionSulfadiazine, TrimethoprimCoptin
How Sulfadiazine, Trimethoprim interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfadiazine, Trimethoprim interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfadiazine, Trimethoprim interactionSulfamerazine, SulfamethazineNeotrizine
How Sulfamerazine, Sulfamethazine interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfamerazine, Sulfamethazine interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfamerazine, Sulfamethazine interactionSulfamethazoleProklar
How Sulfamethazole interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfamethazole interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfamethazole interactionSulfamethizoleThiosulfil Forte
How Sulfamethizole interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfamethizole interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfamethizole interactionSulfamethoxazoleGantanol
How Sulfamethoxazole interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfamethoxazole interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfamethoxazole interactionSulfamethoxazole, TrimethoprimBactrim, Bactrim DS, Bactrim IV, Cotrim, Cotrim DS, Cotrimix +9 more
How Sulfamethoxazole, Trimethoprim interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfamethoxazole, Trimethoprim interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfamethoxazole, Trimethoprim interactionSulfapyridineSulfapyridine
How Sulfapyridine interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfapyridine interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfapyridine interactionSulfisoxazoleGantrisin
How Sulfisoxazole interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Sulfisoxazole interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Sulfisoxazole interactionTedizolid PhosphateSivextro
How Tedizolid Phosphate interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Tedizolid Phosphate interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Tedizolid Phosphate interactionTelavancinVibativ
How Telavancin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Telavancin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Telavancin interactionTelithromycinKetek
How Telithromycin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Telithromycin interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Telithromycin interactionTemafloxacinOmniflox
How Temafloxacin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Temafloxacin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Temafloxacin interactionTetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
How Tetracycline interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Tetracycline interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Tetracycline interactionTicarcillinTicar
How Ticarcillin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Ticarcillin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ticarcillin interactionTicarcillin , ClavulanateTimentin
How Ticarcillin , Clavulanate interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ticarcillin , Clavulanate interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Ticarcillin , Clavulanate interactionTigecyclineTygacil
How Tigecycline interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Tigecycline interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Tigecycline interactionTobramycinBethkis, Kitabis PAK, Nebcin, Tobi Podhaler
How Tobramycin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Tobramycin interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Tobramycin interactionTrimethoprimProloprim, Trimpex
How Trimethoprim interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Trimethoprim interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Trimethoprim interactionTroleandomycinTao
How Troleandomycin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Troleandomycin interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Troleandomycin interactionTrovafloxacinTrovan, Trovan Injection
How Trovafloxacin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Trovafloxacin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Trovafloxacin interactionVancomycinVancocin, Vancoled
How Vancomycin interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Vancomycin interactionProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Vancomycin interactionVancomycin HydrochlorideFirvanq
How Vancomycin Hydrochloride interacts with Probiotic 40 Billion CFU — through 2 ingredients. Tap an ingredient for the detail:
ProduraAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Produra + Vancomycin Hydrochloride interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Vancomycin Hydrochloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Probiotic 40 Billion CFU with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lactobacillus acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
ProDURA
Antibiotic Drugs
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.
Brand information
Manufacturer and brand details for Probiotic 40 Billion CFU, from the product label.
Evlution Nutrition
See all Evlution Nutrition products- Name
- Evlution Nutrition
- Street Address
- 1560 Sawgrass Corporate Parkway, 4th Floor
- City
- Sunrise
- State
- Florida
- ZipCode
- 33323
- Phone Number
- 1(855)385-2300
- Web Address
- Evlnutrition.com
Probiotic 40 Billion CFU by Evlution Nutrition: Common Questions
Does Probiotic 40 Billion CFU by Evlution Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this probiotic while I'm on antibiotics?
What side effects should I watch for?
Is this safe during pregnancy or while breastfeeding?
Will this help my IBS or antibiotic-related diarrhea?
Do I need to refrigerate this product?
What's the difference between this probiotic and others?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Probiotic 40 Billion CFU is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Probiotic 40 Billion CFU’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographBacillus Coagulans
Interacts with 182 drugsBacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...
Read the full Bacillus Coagulans monograph →Sources & How We Checked
Probiotic 40 Billion CFU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 35 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Bacillus Coagulans 20 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
- Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
- Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
- Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
- Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
- Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC