Probiotic + Fiber Drink Mix Berry Breeze Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Probiotic + Fiber Drink Mix Berry Breeze against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Probiotic + Fiber Drink Mix Berry Breeze is a dietary supplement by Dr. Stephanie's with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,053 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Mulberry Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's
Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This powder contains 2 active ingredients: Lactobacillus reuteri, a live probiotic bacterium, and mulberry leaf extract, a plant-based ingredient. The powder also includes several inactive ingredients — inulin and psyllium husk (both fiber sources), citric acid, natural flavoring, stevia for sweetness, and grape skin extract.
Does it work?
Strong evidence
The evidence on mulberry leaf extract is limited. For diabetes, menopausal symptoms, and mouth sores (oral mucositis), the data we hold rates it as having insufficient reliable evidence to rate its usefulness.
The probiotic Lactobacillus reuteri's effectiveness for the intended uses is not covered in the facts we have on file.
How safe is it?
Well-documented data
Orally, black mulberry leaf extracts and related preparations seem to be generally well tolerated, though a complete safety evaluation hasn't been done. One important caution: eating the fruit as food is likely fine, but concentrated supplement doses are less studied, so talk with your doctor before using the extract form unless they've approved it.
There isn't enough data on file to say whether it's safe in pregnancy or while breastfeeding — discuss this with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Check with your pharmacist before starting if you take antidiabetes drugs (there's a moderate risk of low blood sugar) or midazolam (a sedative used in medical procedures). No interactions are documented for the probiotic ingredient we could check.
The bottom line
Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product might appeal to you if you're looking for probiotics and fiber, but it's not a blank slate. If you take diabetes medications or midazolam, you need to check with your pharmacist first.
The supplement form of mulberry leaf is less tested than eating the fruit, so let your doctor know you're considering it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Probiotic + Fiber Drink Mix Berry Breeze, straight from the product label.
| Brand | Dr. Stephanie's |
|---|---|
| Barcode (UPC) | 850018712354 |
| Net contents | 3.96 Ounce(s); 112.5 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2024 |
| DSLD ID | 318642 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s), 40 Calorie(s) | -- |
| Total Carbohydrates | 3 Gram(s), 6 Gram(s) | 1%, 2% |
| Dietary Fiber | 3 Gram(s), 6 Gram(s) | 10%, 20% |
| Lactobacillus reuteri | 0 NP | -- |
| Mulberry Leaf Extract | 500 mg, 1000 mg | -- |
Other ingredients: Inulin, Psyllium Husk, Citric Acid, Natural flavoring, Stevia, Grape Skin Extract
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
How it works: Psyllium husk Promotes smooth digestion & toxin removal. Inulin Prebiotic fiber that reduces hunger & bloating. Probiotics Supports glucose metabolism & microbiome health. White mulberry Post-meal energy and blood sugar support
Formulation
Zero sugar & artificial additives
Meal defense Delicious & gentle Feel less hungry Smooths digestion Supports gut health Cancels carbs
We only use pure ingredients & no artificial fillers.
Suggested/Recommended/Usage/Directions
Dr. Stephanie's tips: Mixes best when shaken or stirred briskly. Use the scoopie to easily put powder into any water bottle for mixing! Drink before your first or biggest meal of the day. Suggested use: Mix 1-2 scoops with 6 oz of cool water and drink once daily before a meal. Add additional water to taste. Shake well. New users: Start with 1 scoop per day and gradually increase as your body adjusts to fiber.
General Statements
25 scoops per jar
FDA Statement of Identity
A Dietary Supplement
Precautions
Warning: For adult use only. Keep out of reach of children.
Not to be used during pregnancy or lactation. Consult with your doctor before use if you have any medical conditions or take medications.
Use only as directed. Do not use if bottle seal is broken. Notice: This food should be eaten with at least a full glass of liquid. Eating this product without enough liquid may cause choking. Do not eat this product if you have difficulty in swallowing.
Storage
Store at 72 degrees F or cooler. Do not expose to excessive heat or moisture.
Contents may settle.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size4.5 Gram(s) Dosage formPowder Servings per container13 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsLactobacillus reuteri
Mulberry Leaf Extract
Interacts with87 drugs
Black mulberry is a nutritious fruit rich in antioxidants and vitamins, and it is generally safe to enjoy as a food. Some early research on its leaf a...
Mulberry Leaf Extract monograph & interactionsOther (inactive) ingredients: Inulin, Psyllium Husk, Citric Acid, Natural flavoring, Stevia, Grape Skin Extract. These complete the product’s ingredient list but are not active constituents.
Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's Drug Interactions
HelloPharmacist Interaction Report
Probiotic + Fiber Drink Mix Berry Breeze contains mulberry leaf extract, which has documented interactions with certain medications.
The most serious concern is with antidiabetes drugs — the mulberry leaf may increase the risk of low blood sugar (hypoglycemia) when combined with these medications. The effect is based on small clinical evidence and lab research showing that mulberry leaf has blood-sugar-lowering effects.
Read the full breakdown — every affected drug type, severity by severity
Additionally, mulberry leaf extract may slow how your body breaks down midazolam (Versed, a sedative used during procedures), potentially raising its levels in your system. This interaction comes from lab research on midazolam metabolism; it hasn't been seen in humans yet.
We could not check the probiotic ingredient (Lactobacillus reuteri) — we hold no interaction data for it. Altogether, these interactions span 86 individual medications.
Use the medication checker on this page to verify your specific drugs before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Probiotic + Fiber Drink Mix Berry Breeze?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Probiotic + Fiber Drink Mix Berry Breeze interact with 2,053 drugs. Click any drug to see the details.
2 of the 3 ingredients in Probiotic + Fiber Drink Mix Berry Breeze interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Mulberry Leaf Extract
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Acetohexamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 1 ingredient. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Alogliptin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Alogliptin, Pioglitazone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Canagliflozin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Canagliflozin, Metformin Hydrochloride interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Carbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbamazepine interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Chlorpropamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Dapagliflozin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Dapagliflozin Propanediol, Metformin interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 1 ingredient. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 1 ingredient. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Empagliflozin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Empagliflozin, Metformin interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Empagliflozin, Metformin Hydrochloride interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Ertugliflozin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ertugliflozin, Metformin Hydrochloride interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 1 ingredient. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 1 ingredient. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Gliclazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Glimepiride interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Glipizide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Probiotic + Fiber Drink Mix Berry Breeze — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Glipizide, Metformin interactionMulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Mulberry Leaf Extract + Glipizide, Metformin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Probiotic + Fiber Drink Mix Berry Breeze with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Mulberry Leaf Extract
Antidiabetes Drugs
Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
One small clinical study shows that black mulberry leaf extract has hypoglycemic effects. This is supported by in vitro research which also suggests that constituents in black mulberry twigs and leaves might have hypoglycemic effects.
Midazolam (Versed)
Theoretically, black mulberry might inhibit the metabolism of midazolam.
In vitro research shows that black mulberry juice can inhibit midazolam 1'-hydroxylation, a reaction that is catalyzed by cytochrome P450 3A4. This effect has not been reported in humans.
Brand information
Manufacturer and brand details for Probiotic + Fiber Drink Mix Berry Breeze, from the product label.
Dr. Stephanie's
See all Dr. Stephanie's products- Name
- Pharmaganics LLC
- Street Address
- 2010 East Center Circle Suite 500
- City
- Plymouth
- State
- MN
- ZipCode
- 55441
- Phone Number
- 1-888-554-0345
- Web Address
- www.DrStephanies.com
Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Probiotic + Fiber Drink Mix Berry Breeze’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographBlack Mulberry
Interacts with 87 drugsBlack mulberry is a nutritious fruit rich in antioxidants and vitamins, and it is generally safe to enjoy as a food. Some early research on its leaf and fruit extracts hints at benefits for...
Read the full Black Mulberry monograph →Sources & How We Checked
Probiotic + Fiber Drink Mix Berry Breeze's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Black Mulberry 5 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Kim, H., Yoon, Y. J., Shon, J. H., Cha, I. J., Shin, J. G., and Liu, K. H. Inhibitory effects of fruit juices on CYP3A activity. Drug Metab Dispos. 2006;34(4):521-523. PubMed
- Xu LJ, Yu MH, Huang CY, et al. Isoprenylated flavonoids from Morus nigra and their PPAR ? agonistic activities. Fitoterapia 2018;127:109-14. PubMed
- Momeni H, Salehi A, Absalan A, Akbari M. Hydro-alcoholic extract of Morus nigra reduces fasting blood glucose and HbA1c% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and in silic
- Navarro-Triviño FJ, Jadczak P, Llamas-Molina JM, Ruiz-Villaverde R. Lichenoid contact dermatitis caused by Morus nigra L. Contact Dermatitis 2021;84(6):484-486.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC