Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Probiotic + Fiber Drink Mix Berry Breeze Ingredients & Drug Interactions

by Dr. Stephanie's

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Probiotic + Fiber Drink Mix Berry Breeze is a dietary supplement by Dr. Stephanie's with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,053 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Mulberry Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.

This powder contains 2 active ingredients: Lactobacillus reuteri, a live probiotic bacterium, and mulberry leaf extract, a plant-based ingredient. The powder also includes several inactive ingredients — inulin and psyllium husk (both fiber sources), citric acid, natural flavoring, stevia for sweetness, and grape skin extract.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestive health, gut health and blood sugar support.
  • We looked for evidence on: Constipation, Diarrhea, Diabetes, Obesity, Bloating, Microbiome balance — and 1 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Diarrhea, Obesity.
  • Also on file: Black Mulberry is rated "Insufficient Reliable Evidence To Rate" for Diabetes.

The evidence on mulberry leaf extract is limited. For diabetes, menopausal symptoms, and mouth sores (oral mucositis), the data we hold rates it as having insufficient reliable evidence to rate its usefulness.

The probiotic Lactobacillus reuteri's effectiveness for the intended uses is not covered in the facts we have on file.

The evidence, ingredient by ingredient Black Psyllium Black Mulberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, black mulberry leaf extracts and related preparations seem to be generally well tolerated, though a complete safety evaluation hasn't been done. One important caution: eating the fruit as food is likely fine, but concentrated supplement doses are less studied, so talk with your doctor before using the extract form unless they've approved it.

There isn't enough data on file to say whether it's safe in pregnancy or while breastfeeding — discuss this with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Black Psyllium Black Mulberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Black Psyllium, Black Mulberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,054 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before starting if you take antidiabetes drugs (there's a moderate risk of low blood sugar) or midazolam (a sedative used in medical procedures). No interactions are documented for the probiotic ingredient we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product might appeal to you if you're looking for probiotics and fiber, but it's not a blank slate. If you take diabetes medications or midazolam, you need to check with your pharmacist first.

The supplement form of mulberry leaf is less tested than eating the fruit, so let your doctor know you're considering it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic + Fiber Drink Mix Berry Breeze, straight from the product label.

Brand Dr. Stephanie's
Barcode (UPC) 850018712354
Net contents 3.96 Ounce(s); 112.5 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318642
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4.5 Gram(s)
Maximum serving Sizes:
9 Gram(s)
Servings per container
13
UPC/BARCODE
850018712354
IngredientAmount% DV
Calories20 Calorie(s), 40 Calorie(s)--
Total Carbohydrates3 Gram(s), 6 Gram(s)1%, 2%
Dietary Fiber3 Gram(s), 6 Gram(s)10%, 20%
Lactobacillus reuteri0 NP--
Mulberry Leaf Extract500 mg, 1000 mg--

Other ingredients: Inulin, Psyllium Husk, Citric Acid, Natural flavoring, Stevia, Grape Skin Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

How it works: Psyllium husk Promotes smooth digestion & toxin removal. Inulin Prebiotic fiber that reduces hunger & bloating. Probiotics Supports glucose metabolism & microbiome health. White mulberry Post-meal energy and blood sugar support

Formulation

Zero sugar & artificial additives

Meal defense Delicious & gentle Feel less hungry Smooths digestion Supports gut health Cancels carbs

We only use pure ingredients & no artificial fillers.

Suggested/Recommended/Usage/Directions

Dr. Stephanie's tips: Mixes best when shaken or stirred briskly. Use the scoopie to easily put powder into any water bottle for mixing! Drink before your first or biggest meal of the day. Suggested use: Mix 1-2 scoops with 6 oz of cool water and drink once daily before a meal. Add additional water to taste. Shake well. New users: Start with 1 scoop per day and gradually increase as your body adjusts to fiber.

General Statements

25 scoops per jar

FDA Statement of Identity

A Dietary Supplement

Precautions

Warning: For adult use only. Keep out of reach of children.

Not to be used during pregnancy or lactation. Consult with your doctor before use if you have any medical conditions or take medications.

Use only as directed. Do not use if bottle seal is broken. Notice: This food should be eaten with at least a full glass of liquid. Eating this product without enough liquid may cause choking. Do not eat this product if you have difficulty in swallowing.

Storage

Store at 72 degrees F or cooler. Do not expose to excessive heat or moisture.

Contents may settle.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4.5 Gram(s) Dosage formPowder Servings per container13 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
3 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Lactobacillus reuteri

0 NP per serving

Mulberry Leaf Extract

Interacts with
87 drugs
500 mg per serving Form: Morus alba Leaf Extract

Black mulberry is a nutritious fruit rich in antioxidants and vitamins, and it is generally safe to enjoy as a food. Some early research on its leaf a...

Mulberry Leaf Extract monograph & interactions

Other (inactive) ingredients: Inulin, Psyllium Husk, Citric Acid, Natural flavoring, Stevia, Grape Skin Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's Drug Interactions

Want to check YOUR meds against Probiotic + Fiber Drink Mix Berry Breeze?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,053Drugs
90 Moderate 1,963 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic + Fiber Drink Mix Berry Breeze with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

Mulberry Leaf Extract2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, black mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
One small clinical study shows that black mulberry leaf extract has hypoglycemic effects. This is supported by in vitro research which also suggests that constituents in black mulberry twigs and leaves might have hypoglycemic effects.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, black mulberry might inhibit the metabolism of midazolam.
In vitro research shows that black mulberry juice can inhibit midazolam 1'-hydroxylation, a reaction that is catalyzed by cytochrome P450 3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Probiotic + Fiber Drink Mix Berry Breeze, from the product label.

Dr. Stephanie's

See all Dr. Stephanie's products
Name
Pharmaganics LLC
Street Address
2010 East Center Circle Suite 500
City
Plymouth
State
MN
ZipCode
55441
Phone Number
1-888-554-0345
Web Address
www.DrStephanies.com
Pharmacist Counseling Corner

Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's: Common Questions

Does Probiotic + Fiber Drink Mix Berry Breeze by Dr. Stephanie's interact with any medications?
Yes. Based on its ingredients, Probiotic + Fiber Drink Mix Berry Breeze has a known interaction with 2,053 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic + Fiber Drink Mix Berry Breeze contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the probiotic in this drink mix?
It's Lactobacillus reuteri, a live bacterium. We don't have interaction data on file for it, but it's a well-known probiotic strain found in many supplements.
Does this have fiber in it?
Yes — inulin and psyllium husk are the fiber sources mixed in. They make up the inactive ingredients that bulk out the powder.
Is mulberry leaf extract proven to work?
Not yet, at least not reliably. For the main uses we have data on — diabetes, menopausal symptoms, and mouth sores — the evidence rates as insufficient, meaning we don't have enough strong proof either way.
Is it safe to drink if I have diabetes?
That's a question for your doctor or pharmacist. Mulberry leaf may lower blood sugar on its own, so combining it with your diabetes medication could push your levels too low. You'll want personalized advice.
Can I use this while pregnant or breastfeeding?
There isn't enough safety data on file to say one way or the other. Talk with your doctor or pharmacist — they can give you guidance based on your individual situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic + Fiber Drink Mix Berry Breeze label
Sources

Sources & How We Checked

Probiotic + Fiber Drink Mix Berry Breeze's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Black Mulberry 5 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Kim, H., Yoon, Y. J., Shon, J. H., Cha, I. J., Shin, J. G., and Liu, K. H. Inhibitory effects of fruit juices on CYP3A activity. Drug Metab Dispos. 2006;34(4):521-523. PubMed
  3. Xu LJ, Yu MH, Huang CY, et al. Isoprenylated flavonoids from Morus nigra and their PPAR ? agonistic activities. Fitoterapia 2018;127:109-14. PubMed
  4. Momeni H, Salehi A, Absalan A, Akbari M. Hydro-alcoholic extract of Morus nigra reduces fasting blood glucose and HbA1c% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and in silic
  5. Navarro-Triviño FJ, Jadczak P, Llamas-Molina JM, Ruiz-Villaverde R. Lichenoid contact dermatitis caused by Morus nigra L. Contact Dermatitis 2021;84(6):484-486.

See these in context on the Black Mulberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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