Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

ProDentim Ingredients & Drug Interactions

by ProDentim

ProDentim label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ProDentim against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

ProDentim is a dietary supplement by ProDentim with 5 active ingredients. Its ingredients are commonly taken for constipation and regularity, prebiotic gut health, blood sugar support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Inulin, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against ProDentim by ProDentim

Ask about any prescription or over-the-counter medication and we check it for interactions with ProDentim by ProDentim — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of ProDentim by ProDentim

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (20 mg) without saying how much of each component you get.

ProDentim is a tablet containing five active ingredients. Three are single-strain probiotics: Lactobacillus paracasei, Bifidobacterium lactis Bl-04, and Lactobacillus reuteri.

The product also includes a Proprietary Probiotic Blend and inulin powder, a fiber that acts as a prebiotic — food for the beneficial bacteria. The inactive ingredients are tricalcium phosphate, microcrystalline cellulose, natural strawberry flavor, and peppermint essential oil.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Inulin's overall clinical evidence instead.

Moderate

Some clinical evidence supports Inulin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Constipation — rated "Possibly Effective" (Natural Medicines).
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).
  • On file: Obesity — rated "Possibly Effective" (Natural Medicines).

Inulin, the prebiotic fiber in ProDentim, is rated Possibly Effective for obesity, constipation, and diabetes. The evidence is Insufficient to rate it for nonalcoholic fatty liver disease (NAFLD) or iron deficiency anemia.

We don't hold effectiveness ratings for the probiotic strains in this product, so we can't say what the research shows for their specific roles in oral or digestive health.

The evidence, ingredient by ingredient Inulin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inulin is generally well tolerated in food amounts, though concentrated supplements warrant a talk with your doctor first. The most common side effects are bloating, gas, diarrhea, constipation, and stomach cramps — especially at doses over 30 grams.

These tend to happen early and often improve with time. Rarely, anaphylaxis has occurred after eating foods high in inulin.

Inulin is rated Likely Safe in pregnancy and lactation. We have no safety data on file for the probiotic strains in this product.

Side effects, ingredient by ingredient Inulin

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inulin.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (Minor risk), check your exact medications with the search tool below before starting ProDentim. We could not verify the three probiotic strains or the proprietary blend against our interaction data, so there may be interactions we don't have documented.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Only minor medication interactions are documented, and safety information is well characterized.

ProDentim is a probiotic and prebiotic blend aimed at oral health. If you take antidiabetes drugs, check your specific medications with the tool on this page before starting, since inulin may affect blood sugar control.

Because we couldn't verify the bacterial strains against our database, talk to your doctor or pharmacist about whether this product fits your health profile and medications before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ProDentim, straight from the product label.

Brand ProDentim
Net contents 30 Soft Tablet(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 298943
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ProDentim by ProDentim, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
IngredientAmount% DV
Lactobacillus paracasei0 NP--
Proprietary Probiotic Blend20 mg--
Bifidobacterium lactis Bl-040 NP--
Lactobacillus reuteri0 NP--
Inulin, Powder100 mg--
Streptococcus salivarius20 mg--

Other ingredients: Tricalcium Phosphate, Microcrystalline Cellulose, Strawberry Flavor, Natural, Peppermint essential Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one soft tablet one or up to two times a day, or as recommended by your healthcare provider, ideally after brushing teeth or using mouthwash. Allow it to completely dissolve in mouth.

Precautions

Caution: As with any dietary supplement, you should consult your healthcare provider before use, especially if pregnant, nursing, have a medical condition, taking medications, or have known adverse reactions or allergies.

Caution: As with any dietary supplement, you should consult your healthcare provider before use, especially if pregnant, nursing, have a medical condition, taking medications, or have known adverse reactions or allergies.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Certified Good Manufacturing Practices

Made in the USA Using foreign and U.S. ingredients

Manufactured in a FDA registered facility

Formula

Advanced oral probiotics

Formulation

Clinically researched formula for: Healthy teeth and gums Long lasting fresh breath Ear, nose and throat immune health

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ProDentim by ProDentim label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ProDentim label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ProDentim by ProDentim

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

20 mg per serving
  • › Lactobacillus paracasei
  • › Bifidobacterium lactis Bl-04
  • › Lactobacillus reuteri

Inulin, Powder

Interacts with
86 drugs
100 mg per serving Form: Chicory

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...

Inulin, Powder monograph & interactions

Streptococcus salivarius

20 mg per serving

Other (inactive) ingredients: Tricalcium Phosphate, Microcrystalline Cellulose, Strawberry Flavor, Natural, Peppermint essential Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

ProDentim by ProDentim Drug Interactions

Want to check YOUR meds against ProDentim?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Minor

Ingredients driving the most interactions

Inulin, Powder 86

Individual Drug Interactions

The ingredients in ProDentim interact with 86 drugs. Click any drug to see the details.

1 of the 5 ingredients in ProDentim interact with drugs. Each result below shows which ingredient is responsible. Inulin, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in ProDentim with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inulin, Powder1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
Inulin, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ProDentim, from the product label.

ProDentim

See all ProDentim products
Name
ProDentim
City
Akron
State
OH
ZipCode
44301
Pharmacist Counseling Corner

ProDentim by ProDentim: Common Questions

Does ProDentim by ProDentim interact with any medications?
Yes. Based on its ingredients, ProDentim has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ProDentim contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does inulin cause bloating or gas?
Yes — bloating, gas, stomach cramps, and changes in bowel habits are common, especially at higher doses or when you first start. These effects often settle down over time. If they're bothersome, starting with a smaller amount or taking it with food may help.
Is ProDentim safe during pregnancy or breastfeeding?
The inulin in ProDentim is rated Likely Safe in pregnancy and lactation. We don't have safety data for the probiotic strains, so talk to your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.
Can ProDentim help me lose weight or manage my diabetes?
Inulin, a key ingredient here, is rated Possibly Effective for both obesity and diabetes. That means some evidence supports it, but more research is needed. It's not a replacement for your other treatments — talk to your doctor about how it might fit into your routine.
What are the inactive ingredients?
ProDentim also contains tricalcium phosphate, microcrystalline cellulose, natural strawberry flavor, and peppermint essential oil. These are fillers, binders, and flavoring agents.
Can I take ProDentim if I'm on blood sugar medication?
Inulin may theoretically increase the risk of low blood sugar with antidiabetes drugs, though the research on this is still mixed. Check your specific medications with the tool on this page, and run it by your doctor or pharmacist before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ProDentim is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ProDentim label
Go deeper

The Full Monographs Behind ProDentim’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inulin

Interacts with 86 drugs

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...

Read the full Inulin monograph →
Sources

Sources & How We Checked

ProDentim's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inulin 17 references
  1. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
  2. Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  5. Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
  6. Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
  7. Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
  8. Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
  9. Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
  10. Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
  11. Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
  12. Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
  13. Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
  14. Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
  15. Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
  16. Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
  17. Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed

See these in context on the Inulin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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