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Dietary supplement

ProstaSorb Ingredients & Drug Interactions

by Tesseract Medical Research

ProstaSorb label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ProstaSorb against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ProstaSorb is a dietary supplement by Tesseract Medical Research with 3 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.Based on those ingredients, 175 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto Extract, Cucurbita pepo Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against ProstaSorb by Tesseract Medical Research

Ask about any prescription or over-the-counter medication and we check it for interactions with ProstaSorb by Tesseract Medical Research — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of ProstaSorb by Tesseract Medical Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Prostasorb Complex” is a proprietary blend — the label gives one combined amount (300 mg) without saying how much of each component you get.

ProstaSorb has three active ingredients. Pygeum africanum Extract is derived from African plum tree bark and is traditionally used for men's prostate health.

Saw Palmetto Extract comes from the berry of the saw palmetto plant and is also used for prostate symptoms. Cucurbita pepo Extract is pumpkin seed extract, added for its potential role in urinary and prostate support.

The product also contains inactive ingredients — hypromellose, silicon dioxide, and other binders and capsule materials — that hold the formula together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Prostate and urinary tract health support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Non-neurogenic lower urinary tract symptoms (LUTS), Overactive bladder, Prostatitis, Urinary retention — and 2 related terms.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH).
  • Also on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH).

The evidence for ProstaSorb's ingredients is mixed. Pygeum africanum is likely effective for benign prostatic hyperplasia (BPH) — enlarged prostate — but the data on its long-term safety is limited.

Saw Palmetto Extract is listed as possibly ineffective for BPH, so it may not deliver the prostate relief you're hoping for. Pumpkin seed extract (Cucurbita pepo) is possibly effective for BPH.

For the other uses listed in the research — including sexual desire, Alzheimer disease, and hair loss — there isn't enough reliable evidence in our data to rate whether these ingredients help.

The evidence, ingredient by ingredient Pygeum Saw Palmetto Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum and Saw Palmetto are generally well tolerated short-term, but long-term safety data are limited. The most common side effects across these ingredients are mild: nausea, abdominal pain or discomfort, constipation, diarrhea, dizziness, headache, and fatigue.

Saw palmetto has rare reports of skin reactions and heart rhythm changes; pumpkin seed is generally safe as a food but concentrated supplements lack long-term study. Both Pygeum and Saw Palmetto carry safety warnings against use in pregnancy and breastfeeding due to insufficient data and possible hormone effects.

Pumpkin seed has not enough data on concentrated supplements in pregnancy and breastfeeding — discuss with your pharmacist if you're pregnant or nursing.

Side effects, ingredient by ingredient Pygeum Saw Palmetto Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Pumpkin, Saw Palmetto.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 175 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting ProstaSorb, run it through the checker below if you take blood thinners or antiplatelet drugs — Saw Palmetto may increase bleeding risk (Moderate severity). Also check if you're on estrogens, birth control pills, or lithium, as this product may interfere with them (Moderate severity for each).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

ProstaSorb is aimed at men with prostate symptoms, combining ingredients with some evidence for BPH support — though saw palmetto's track record is weak. The main thing to do before you start is check your medications against the interaction list below, especially if you take blood thinners, birth control, or lithium.

If you're pregnant, breastfeeding, or taking any hormonal medications, talk to your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ProstaSorb, straight from the product label.

Brand Tesseract Medical Research
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 328495
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ProstaSorb by Tesseract Medical Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Pygeum africanum Extract0 NP--
Prostasorb Complex300 mg--
Saw Palmetto Extract0 NP--
Cucurbita pepo Extract0 NP--

Other ingredients: CyLoc, Hypromellose, Hydroxypropyl Methylcellulose, Calcium Laurate, Leucine, Amylase, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take 1 or more capsules two times daily or as recommended by your health-care practitioner.

Precautions

Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Storage

Store tightly sealed in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Formulation

Hypoallergenic

Formula

Solubility enhanced extracts of Saw Palmetto (Serenoa repens), Cucurbita pepo and Pygeum africanum, in an octadextrin matrix molecular trap compounded with DexKey release agent (patent pending, AI Czap, Czap R&D, licensed by Tesseract Medical Research, LLC).

Brand IP Statement(s)

Solubility enhanced extracts of Saw Palmetto (Serenoa repens), Cucurbita pepo and Pygeum africanum, in an octadextrin matrix molecular trap compounded with DexKey release agent (patent pending, AI Czap, Czap R&D, licensed by Tesseract Medical Research, LLC).

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ProstaSorb by Tesseract Medical Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ProstaSorb label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ProstaSorb by Tesseract Medical Research

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Prostasorb Complex

300 mg per serving

Other (inactive) ingredients: CyLoc, Hypromellose, Hydroxypropyl Methylcellulose, Calcium Laurate, Leucine, Amylase, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

ProstaSorb by Tesseract Medical Research Drug Interactions

Want to check YOUR meds against ProstaSorb?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
175Drugs
175 Moderate

Ingredients driving the most interactions

Saw Palmetto Extract 174
Cucurbita pepo Extract 1

Individual Drug Interactions

The ingredients in ProstaSorb interact with 175 drugs. Click any drug to see the details.

2 of the 3 ingredients in ProstaSorb interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto Extract Cucurbita pepo Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in ProstaSorb with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Saw Palmetto Extract3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto Extract full monograph & interactions

Cucurbita pepo Extract1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Cucurbita pepo Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ProstaSorb, from the product label.

Tesseract Medical Research

See all Tesseract Medical Research products
Name
Tesseract Medical Research, LLC
Street Address
1370 Trancas St., #376
City
Napa
State
CA
ZipCode
94558
Web Address
www.TessMed.com
Pharmacist Counseling Corner

ProstaSorb by Tesseract Medical Research: Common Questions

Does ProstaSorb by Tesseract Medical Research interact with any medications?
Yes. Based on its ingredients, ProstaSorb has a known interaction with 175 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ProstaSorb contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this interfere with my birth control?
Saw Palmetto Extract in this product may reduce how well birth control works by blocking estrogen activity. It's a Moderate severity interaction, so talk to your doctor or pharmacist before adding this product if you're on hormonal contraceptives.
What if I'm taking a blood thinner like warfarin?
Saw Palmetto is reported to lengthen bleeding time, which could raise your bleeding risk if you're on blood thinners or antiplatelet drugs like aspirin. This is a Moderate concern, so don't start without checking with your pharmacist first.
Is this safe to take while pregnant?
No. Both Pygeum and Saw Palmetto are flagged as not safe in pregnancy due to possible hormone effects and lack of safety data. Pumpkin seed extract also lacks enough study. Talk to your doctor if you're pregnant or trying to conceive.
Can I take this if I'm breastfeeding?
The safety data aren't strong enough for any of these ingredients while breastfeeding. There isn't enough information to say either way, so check with your pharmacist or doctor for personalized advice.
Does this actually work for prostate problems?
Pygeum is likely effective for benign prostatic hyperplasia. Saw Palmetto, though, is listed as possibly ineffective for the same condition — the evidence doesn't back it up well. Pumpkin seed is possibly effective. So the product's track record is mixed.
What are the most common side effects?
The main ones are mild and reversible: nausea, abdominal pain or discomfort, diarrhea, constipation, dizziness, headache, and fatigue. These were similar to placebo in trials, so they're not frequent. Rare reports include skin reactions and heart rhythm changes with saw palmetto.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ProstaSorb is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ProstaSorb label
Go deeper

The Full Monographs Behind ProstaSorb’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pygeum

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...

Read the full Pygeum monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph →
Sources

Sources & How We Checked

ProstaSorb's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Saw Palmetto 22 references
  1. Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
  3. Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
  4. Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
  5. Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
  6. Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
  7. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  8. Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
  9. Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
  10. Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
  11. Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
  12. Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
  13. Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
  14. Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
  15. Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
  16. Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
  17. Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
  18. Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
  19. Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
  20. Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
  21. Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
  22. Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed

See these in context on the Saw Palmetto monograph →

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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