Prostol Ingredients & Drug Interactions
by Nature's Way
What is this page for?
First and foremost: checking Prostol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Prostol is a dietary supplement by Nature's Way with 2 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 336 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sabal extract, Urtica extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Prostol by Nature's Way
Ask about any prescription or over-the-counter medication and we check it for interactions with Prostol by Nature's Way — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Prostol by Nature's Way
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Prostol contains 2 active ingredients: sabal extract (saw palmetto) and urtica extract (stinging nettle). Saw palmetto is used to help with urinary and prostate symptoms, and stinging nettle is traditionally used to support urinary and prostate health as well.
The softgel also contains several inactive ingredients — plant glycerides, gelatin, glycerin, soybean oil, and color additives (caramel, titanium dioxide, and carmine) — that serve as the capsule shell and filler.
Does it work?
Leans against
The evidence for these ingredients is mixed. Saw palmetto is possibly ineffective for benign prostatic hyperplasia (enlarged prostate) based on the data we hold, though it's rated possibly effective for TURP (transurethral resection of the prostate, a surgical procedure).
Stinging nettle is possibly effective for diabetes, but we don't have established evidence on file for its use in prostate or urinary symptoms. For other conditions like hay fever, anemia, or asthma, the evidence is either insufficient or not rated in our data.
How safe is it?
Well-documented data
Both ingredients are generally well tolerated when used as directed. Saw palmetto's most common side effects are mild and reversible — abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, nausea, and decreased libido have been reported.
Rare cases of heart rhythm problems have also been documented. Stinging nettle commonly causes constipation or diarrhea, and case reports describe rare liver injury and severe tongue swelling when the raw plant was used improperly.
Both ingredients are rated Likely Unsafe in pregnancy due to hormonal effects and insufficient safety data. Saw palmetto should be avoided while breastfeeding.
Stinging nettle's safety during breastfeeding has not been established, so talk with your doctor or pharmacist before using it if you're nursing.
Meds to double-check
Moderate interaction found
Before taking Prostol, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate risk of increased bleeding). Also double-check if you're on hormonal contraceptives or estrogen therapy (Moderate risk of reduced effectiveness), diabetes medications (Moderate additive effect on blood sugar), lithium (Moderate risk of lithium buildup), diuretics, or warfarin specifically.
The bottom line
Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Prostol is meant to support prostate and urinary health, but the evidence for that purpose is not strong in our data. If you take any blood thinners, hormonal contraceptives, estrogens, diabetes medications, lithium, diuretics, or warfarin, you'll need to check this product with your own doctor or pharmacist before starting — the interactions could affect how those drugs work.
Do not take this product if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Prostol, straight from the product label.
| Brand | Nature's Way |
|---|---|
| Barcode (UPC) | 033674149331 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 26, 2020 |
| DSLD ID | 213090 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Prostol by Nature's Way, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sabal extract | 160 mg | -- |
| Urtica extract | 120 mg | -- |
Other ingredients: Plant Glycerides, Gelatin, Glycerin, Soybean Oil, Carmel color, Titanium Dioxide color, Carmine color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Dual action prostate support
Gluten free. No salt, yeast-derived ingredients, corn, wheat, dairy products, or artificial flavors, or preservatives.
Formula
Prostol brings a synergistic combination of Saw Palmetto (Sabal) and Nettle that, through clinical research, has been shown to support prostate health.
Saw Palmetto & Nettle 280 mg per serving
General Statements
At Nature's Way we believe nature knows best. That's why our mission is to seek out the best herbs the earth has to give. It's the way we deliver uncompromising quality and help you live healthier.
Nature’s Way Since 1969
Product of Germany
Bottles made from 97% post-consumer recycled plastic
FDA Disclaimer Statement
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary supplement
Suggested/Recommended/Usage/Directions
Recommendation: take 1 softgel twice daily.
Precautions
Not formulated for women.
If you are taking any medications, consult a healthcare professional before use.
Contains soy
Keep out of reach of children.
Safety sealed with printed inner seal. Do not use if seal is broken or missing.
Brand IP Statement(s)
2019 Nature’s Way Brands, LLC
Seals/Symbols
Quality Global Sourcing Bottled & Tested In the USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Prostol by Nature's Way label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Prostol by Nature's Way
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sabal extract
Interacts with174 drugs
Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...
Sabal extract monograph & interactionsUrtica extract
Interacts with164 drugs
Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...
Urtica extract monograph & interactionsOther (inactive) ingredients: Plant Glycerides, Gelatin, Glycerin, Soybean Oil, Carmel color, Titanium Dioxide color, Carmine color. These complete the product’s ingredient list but are not active constituents.
Prostol by Nature's Way Drug Interactions
HelloPharmacist Interaction Report
Prostol by Nature's Way contains saw palmetto and stinging nettle, both of which interact with medications.
The most serious concern is saw palmetto's potential to increase bleeding risk with blood thinners and antiplatelet drugs (anticoagulants and antiplatelet agents) — a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Saw palmetto also affects hormonal medications. It may reduce the effectiveness of estrogens and hormonal contraceptives through antiestrogenic effects.
Stinging nettle adds several Moderate interactions of its own: it may lower blood sugar additively with diabetes medications, increase lithium levels by reducing its excretion, and potentially decrease warfarin (Coumadin) effectiveness because it contains vitamin K.
Stinging nettle may also have additive effects with diuretic drugs. Altogether, these interactions span 336 individual medications.
Use the medication checker below to search your exact drugs before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Prostol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Prostol interact with 336 drugs. Click any drug to see the details.
2 of the 2 ingredients in Prostol interact with drugs. Each result below shows which ingredient is responsible. Sabal extract Urtica extract
AbciximabReoPro
How Abciximab interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Prostol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sabal extract
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Urtica extract
Antidiabetes Drugs
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.
Diuretic Drugs
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.
Lithium
Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.
Warfarin (Coumadin)
There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.
Brand information
Manufacturer and brand details for Prostol, from the product label.
Nature's Way
See all Nature's Way products- Name
- Nature's Way Brands, LLC
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- 1-800-962-8873
- Web Address
- naturesway.com
Prostol by Nature's Way: Common Questions
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Does this actually work for prostate problems?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Prostol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Prostol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Saw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographStinging Nettle
Interacts with 164 drugsStinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...
Read the full Stinging Nettle monograph →Sources & How We Checked
Prostol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 45 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Saw Palmetto 22 references
- Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
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