Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Pure Apple Cider Vinegar 1875 mg Ingredients & Drug Interactions

by NutriRise

Pure Apple Cider Vinegar 1875 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Apple Cider Vinegar 1875 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Apple Cider Vinegar 1875 mg is a dietary supplement by NutriRise with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 162 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pure Apple Cider Vinegar 1875 mg by NutriRise

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Apple Cider Vinegar 1875 mg by NutriRise — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Pure Apple Cider Vinegar 1875 mg by NutriRise

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: apple cider vinegar at 1875 mg per capsule. The remaining ingredients are inert — a vegetable capsule shell, silica (a flow agent), and L-leucine (an amino acid used to prevent clumping).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Apple Cider Vinegar product and its label doesn't state a use — see Apple Cider Vinegar's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have enough reliable evidence to say whether Pure Apple Cider Vinegar works for acne, athletic performance, cognitive function, dental plaque, depression, or atopic dermatitis (eczema). The evidence we hold rates all six of these claims as insufficient, which means the data isn't established enough to make a recommendation either way.

The evidence, ingredient by ingredient Apple Cider Vinegar

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In the small amounts you'd get from food, apple cider vinegar is generally well tolerated. Short-term use at medicinal doses also appears well tolerated in most people.

However, large doses or long-term use raise concerns: rare cases have reported low potassium (hypokalemia), elevated renin levels, and bone loss (osteoporosis) with chronic high-dose use — one documented case involved 250 mL daily for 6 years. Topical application carries its own risk; apple cider vinegar can cause chemical burns and skin irritation on the skin.

Safety data on large supplement doses is limited, so if you're considering higher amounts, talk with your doctor first.

Side effects, ingredient by ingredient Apple Cider Vinegar

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Apple Cider Vinegar.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 162 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take diuretics (water pills) or digoxin — these carry moderate risk of serious potassium loss and heart effects. Also clear it if you use insulin or any diabetes medication, as it might lower blood sugar.

The search tool on this page can help you verify your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is one to clear before you start, especially if you take water pills, heart medications like digoxin, insulin, or diabetes drugs. The main risk is low potassium — a serious concern with some medications.

If you're otherwise healthy and take no medications, food amounts are generally fine, but talk to your pharmacist or doctor before using it as a supplement, particularly long-term or in large doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Apple Cider Vinegar 1875 mg, straight from the product label.

Brand NutriRise
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 229958
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Apple Cider Vinegar 1875 mg by NutriRise, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetarian Capsule(s)
Maximum serving Sizes:
3 Vegetarian Capsule(s)
Servings per container
30
IngredientAmount% DV
Apple Cider Vinegar1875 mg--

Other ingredients: Vegetable Capsule, Silica, L-Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Get your free bottle at Free.NutriRise.com

Please recycle

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take three (3) capsules daily. For best results, take one (1) capsule three times a day, 20-30 min. before a meal with an 8 oz. glass of water or as directed by your healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

All-natural Extra-strength - 1875 mg Natural cleanse & detox Advanced weight management Supports healthy digestion Helps eliminate toxins

Non-GMO Gluten & dairy free ingredients

FDA Statement of Identity

Dietary Supplement

Formula

100% Natural ingredients

Seals/Symbols

Made in USA FDA Registered Facility Lab Tested 3rd Party Certified for Potency & Purity

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Apple Cider Vinegar 1875 mg by NutriRise label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Apple Cider Vinegar 1875 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Apple Cider Vinegar 1875 mg by NutriRise

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Apple Cider Vinegar

Interacts with
162 drugs
1875 mg per serving

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Other (inactive) ingredients: Vegetable Capsule, Silica, L-Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Apple Cider Vinegar 1875 mg by NutriRise Drug Interactions

Want to check YOUR meds against Pure Apple Cider Vinegar 1875 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
162Drugs
89 Moderate 73 Minor

Ingredients driving the most interactions

Apple Cider Vinegar 162

Individual Drug Interactions

The ingredients in Pure Apple Cider Vinegar 1875 mg interact with 162 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure Apple Cider Vinegar 1875 mg interact with drugs. Each result below shows which ingredient is responsible. Apple Cider Vinegar

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Apple Cider Vinegar 1875 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Apple Cider Vinegar 1875 mg, from the product label.

NutriRise

See all NutriRise products
Name
NutriRise
City
Houston
State
TX
Phone Number
+1 (855) 302-3867
Web Address
http://nutririse.com
Pharmacist Counseling Corner

Pure Apple Cider Vinegar 1875 mg by NutriRise: Common Questions

Does Pure Apple Cider Vinegar 1875 mg by NutriRise interact with any medications?
Yes. Based on its ingredients, Pure Apple Cider Vinegar 1875 mg has a known interaction with 162 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Apple Cider Vinegar 1875 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does apple cider vinegar really work for acne or skin problems?
We don't have enough reliable evidence to say. The data we hold rates it as insufficient for acne and eczema. If you're thinking about using it on your skin, keep in mind that apple cider vinegar can cause chemical burns and irritation when applied directly — talk to your doctor before trying it topically.
Can I take this if I'm on a water pill?
That's a conversation to have with your doctor or pharmacist first. Apple cider vinegar can lower your potassium level, and water pills do the same thing — combining them raises your risk of dangerously low potassium. Your provider can tell you whether it's safe for you.
What does 'hypokalemia' mean?
It's low blood potassium. Your body needs potassium for your heart and muscles to work right, so running low can cause serious problems — especially if you're also taking heart medications like digoxin.
Is this safe if I take insulin or diabetes medication?
Apple cider vinegar might lower blood sugar on its own, so combined with insulin or diabetes drugs there's a theoretical risk of blood sugar dropping too low (hypoglycemia). Check with your doctor or pharmacist before you start — they can tell you if it's okay for you and whether you need monitoring.
How much apple cider vinegar is in each capsule?
Each capsule contains 1875 mg of apple cider vinegar. The capsule also contains inactive ingredients: a vegetable capsule shell, silica, and L-leucine.
Is it safe to take this long-term?
We don't have much safety data on long-term supplement use at large doses. Rare cases of low potassium, elevated renin, and bone loss have been reported with chronic high-dose use over years. Talk to your doctor before taking it regularly in supplement form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Apple Cider Vinegar 1875 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Apple Cider Vinegar 1875 mg label
Go deeper

The Full Monographs Behind Pure Apple Cider Vinegar 1875 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph →
Sources

Sources & How We Checked

Pure Apple Cider Vinegar 1875 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Apple Cider Vinegar 11 references
  1. Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
  3. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
  4. Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
  5. Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
  6. Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
  7. Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
  8. Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
  9. Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
  10. Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
  11. Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro

See these in context on the Apple Cider Vinegar monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team