Interactions on record — worth a quick check against your medications. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Pure CLA 1250 Ingredients & Drug Interactions

by SAN

Pure CLA 1250 label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure CLA 1250 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure CLA 1250 is a dietary supplement by SAN with 4 active ingredients. Its ingredients are commonly taken for heart health, healthy cooking fat, skin moisturizing.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pure CLA 1250 by SAN

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure CLA 1250 by SAN — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Pure CLA 1250 by SAN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “Conjugated Linoleic Acid” is listed as a grouped ingredient — the label gives one combined amount (1 Gram(s)) without saying how much of each component you get.
  • “ultra pure highly concentrated Safflower Oil” is listed as a grouped ingredient — the label gives one combined amount (1.25 Gram(s)) without saying how much of each component you get.

Pure CLA 1250 contains six active ingredients centered on conjugated linoleic acid (CLA) and related fatty acids. The formula includes conjugated linoleic acid itself, oleic acid (a monounsaturated fat), palmitic acid (a saturated fat), stearic acid, and other isomers, delivered through a highly concentrated safflower oil base.

The softgel capsule also contains bovine gelatin, glycerin, purified water, and caramel as inactive binders and colorants.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oleic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: body fat reduction and weight management.
  • We looked for evidence on: Obesity, body composition, weight loss, metabolic health.
  • The closest evidence on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

Oleic acid in this product is possibly effective for lowering cholesterol and supporting heart health, based on research comparing it to other dietary fats. The evidence we hold doesn't establish effectiveness ratings for the conjugated linoleic acid itself or the other fatty acid components in this formula.

The evidence, ingredient by ingredient Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic acid from foods—like olive oil—is generally recognized as safe. However, concentrated supplement doses of oleic acid have not been well studied, especially in pregnancy and during breastfeeding; the data we hold advises caution.

No adverse effects are documented in our data for this product's ingredients.

Side effects, ingredient by ingredient Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (blood sugar–lowering medications), check with your pharmacist or doctor before starting Pure CLA 1250. Oleic acid may increase how well these medications work, which could lower your blood sugar more than expected.

Several ingredients in this product haven't been checked against our drug database, so run your complete medication list through the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This product may be worth considering if you're interested in fatty acid supplementation for cholesterol or heart health, but it's most important if you take diabetes medications—the oleic acid could make them work more strongly. Talk with your doctor or pharmacist about whether this product fits your health plan and whether your current medications need any adjustments.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure CLA 1250, straight from the product label.

Brand SAN
Barcode (UPC) 672898126010
Net contents 18 Softgel(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175246
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure CLA 1250 by SAN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
18
UPC/BARCODE
672898126010
IngredientAmount% DV
Calories12 Calorie(s)--
Stearic Acid24 mg--
Calories from Fat12 Calorie(s)--
Total Fat1 Gram(s)2%
Conjugated Linoleic Acid1 Gram(s)--
Oleic Acid100 mg--
Saturated Fat0 Gram(s)--
Palmitic Acid63 mg--
Cholesterol0 Gram(s)--
Conjugated Linoleic Acid450 mg--
Conjugated Linoleic Acid450 mg--
Other Isomers100 mg--
Trans Fat0 Gram(s)--
ultra pure highly concentrated Safflower Oil1.25 Gram(s)--

Other ingredients: Bovine Gelatin, Glycerin, purified Water, Caramel

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Use: Take 1 softgel 3-4 times daily with a meal or as directed by your health care provider.

Precautions

Warning: Do not exceed 6 softgels in any 24 hour period. Use only under the advice of your physician if you have a medical condition.

Keep out of reach of children.

Manufactured in a facility that also processes egg, shellfish, fish, soy, peanuts, tree nuts and milk ingredients.

Storage

Storage Instructions: Protect from heat, freezing or humidity (above 65%) Keep container tightly closed when not in use.

Formula

Description: CLA or Conjugated Linolenic Acid is a naturally occurring fatty acid in animal tissue and food sources, including beef, poultry, eggs and dairy products such as cheeses, milk and yogurt.

Ultra pure CLA

General Statements

Supplementation may have a substantial impact on how effectively our body chemically decomposes and deposits fat in our cells. Recent research has shown that use of CLA has proven to be extremely effective in reducing body fat and increasing lean muscle mass.

SAN products are manufactured under GMP (Good Manufacturing Practices) standards with stringent quality control guidelines. Additionally, each lot produced by SAN is independently tested for purity and potency by HPLC analysis to ensure only the highest quality ingredients in our innovative formulas.

Live a vibrant life!

Quick release softgels HPLC tested & certified

Made in the U.S.A.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Manufactured in an FDA registered facility

HPLC & FTIR Tested Quality approved

GMP Certified GMP Manufactured FDA Licensed Facility

FDA Statement of Identity

Dietary Supplement

General

Ver 1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure CLA 1250 by SAN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure CLA 1250 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure CLA 1250 by SAN

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container18 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Ultra pure highly concentrated Safflower Oil

1.25 Gram(s) per serving Form: Conjugated Linoleic Acid
  • › Stearic Acid
  • › Conjugated Linoleic Acid
  • › Oleic Acid
  • › Palmitic Acid

Other (inactive) ingredients: Bovine Gelatin, Glycerin, Purified Water, Caramel. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure CLA 1250 by SAN Drug Interactions

Want to check YOUR meds against Pure CLA 1250?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Oleic Acid 86

Individual Drug Interactions

The ingredients in Pure CLA 1250 interact with 86 drugs. Click any drug to see the details.

1 of the 4 ingredients in Pure CLA 1250 interact with drugs. Each result below shows which ingredient is responsible. Oleic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure CLA 1250 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Oleic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure CLA 1250, from the product label.

SAN

See all SAN products
Name
San Corporation
Street Address
716 N. Ventura Road #431
City
Oxnard
State
CA
Phone Number
(888) 519-9300
Web Address
Vibrantlife.net
Pharmacist Counseling Corner

Pure CLA 1250 by SAN: Common Questions

Does Pure CLA 1250 by SAN interact with any medications?
Yes. Based on its ingredients, Pure CLA 1250 has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure CLA 1250 contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is CLA, and what's it supposed to do?
CLA stands for conjugated linoleic acid, a type of fatty acid. This product focuses on CLA and related fatty acids like oleic acid. Oleic acid—one component here—is possibly effective for cholesterol and heart health based on research comparing different dietary fats.
Will this interact with my diabetes medication?
Yes, possibly. The oleic acid in this product may increase the effects of blood sugar–lowering drugs, meaning your medication could work more strongly than usual. Check with your doctor or pharmacist before you start, especially if your blood sugar levels are already well controlled.
Is this safe during pregnancy or breastfeeding?
The oleic acid in this product comes from food sources in the diet safely, but concentrated supplement doses haven't been well studied in pregnancy or breastfeeding. There isn't enough data to know if it's safe at supplement levels; talk with your doctor for personalized advice.
What are the inactive ingredients?
The softgel capsule contains bovine gelatin, glycerin, purified water, and caramel. These are binders, humectants, and a colorant—they help form and color the capsule but aren't active ingredients.
Does this product have side effects?
No adverse effects are documented in our data for this product's ingredients. That doesn't mean none can occur, but clinical trials or reports haven't flagged any in our records.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure CLA 1250 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure CLA 1250 label
Go deeper

The Full Monographs Behind Pure CLA 1250’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Sources

Sources & How We Checked

Pure CLA 1250's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 19 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
  3. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
  4. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
  5. Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
  6. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
  7. FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
  8. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
  9. Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
  11. Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
  12. Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
  13. Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
  14. Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
  15. Ben Fradj MK, Ouanes Y, Hadj-Taieb S, et al. Decreased oleic acid and marine n?-?3 polyunsaturated fatty acids in Tunisian patients with urothelial bladder cancer. Nutr Cancer. 2018;70(7):1043-1050.
  16. de Silva PS, Luben R, Shrestha SS, Khaw KT, Hart AR. Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries. Eur J Gastroenterol Hepatol. 2014;26(1):11-8. PubMed
  17. Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. Lipids. 2001;36(1):1-6. PubMed
  18. Lin HC, van Citters GW, Heimer F, Bonorris G. Slowing of gastrointestinal transit by oleic acid: a preliminary report of a novel, nutrient-based treatment in humans. Dig Dis Sci. 2001;46(2):223-9. PubMed
  19. Li D, Tong Y, Li Y. Associations between dietary oleic acid and linoleic acid and depressive symptoms in perimenopausal women: The Study of Women's Health Across the Nation. Nutrition. 2020 Mar;71:110602. PubMed

See these in context on the Oleic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team