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Dietary supplement

Pure Stevia 90% Steviosides Extract Powder Ingredients & Drug Interactions

by HARD RHINO

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pure Stevia 90% Steviosides Extract Powder is a dietary supplement by HARD RHINO with 1 active ingredient. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia 90% Steviodies Extract Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pure Stevia 90% Steviosides Extract Powder by HARD RHINO

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a single-ingredient supplement: stevia extract standardized to 90% steviosides (the active compounds that make stevia sweet). There are no inactive ingredients listed.

Stevia is a zero-calorie sweetener derived from the stevia plant leaf.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Stevia product and its label doesn't state a use — see Stevia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for stevia's effectiveness is limited. For blood sugar control, weight management, and blood pressure, we don't yet hold enough reliable evidence to rate how well it works.

Some small clinical studies suggest stevia might affect blood sugar levels when taken with food, and animal research hints at blood pressure effects, but human research hasn't confirmed these findings clearly enough to say stevia reliably does what people hope it will.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Purified stevia at typical food amounts is generally well tolerated. The most common side effects—bloating, dizziness, headache, muscle pain, nausea, and numbness—tend to be mild and often resolve within the first week.

Rare allergic reactions have been reported. Because this is a supplement dose rather than a food amount, safety data are limited; use caution and talk with your doctor or pharmacist if you have concerns, especially if you're taking other medications or have a medical condition.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this stevia product, double-check with your doctor or pharmacist if you take lithium (Moderate interaction risk), blood pressure medications, or diabetes drugs (Minor risks). No interactions are documented beyond these three medication categories, but 259 individual drugs across them are potentially affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to people looking for a calorie-free sweetener, but the evidence that it helps with blood sugar, blood pressure, or weight isn't solid yet. If you take lithium, blood pressure medication, or diabetes medication, check with your doctor or pharmacist before using it—the interaction risks are real, even if they're not guaranteed to affect you.

Start by reviewing your exact medications using the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Stevia 90% Steviosides Extract Powder, straight from the product label.

Brand HARD RHINO
Net contents 500 Gram(s); 1.1 lb
Market status On market
Date entered into DSLD Jun 25, 2014
DSLD ID 34542
Product type Botanical
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Stevia 90% Steviosides Extract Powder by HARD RHINO, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
40 mg
Maximum serving Sizes:
40 mg
Servings per container
12500
IngredientAmount% DV
Stevia 90% Steviodies Extract Powder40 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No added fillers No flow agents No driers No other ingredients

Allergens: This product contains NO Soy, Milk & Byproducts, Eggs, Fish, Shellfish, Wheat, Gluten, Tree Nuts, or Sesame Seeds.

Suggested/Recommended/Usage/Directions

Suggested Use: Typical dosages for Stevia start at 40 mg. Stevia 90% is 300 times sweeter than sugar. As with all of our powders, a micro scale is strongly recommended for proper dosage.

Suggested Use: Typical dosages start at 40 mg, Stevia is 300x sweeter than sugar.

Storage

Storage: Store in a cool & dry place. Keep away from strong light & heat.

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

WARNING: A scale is required for accurate measurements.

Keep away from children.

Do not take this or any other supplement if you are pregnant or nursing.

Do not take if you have high blood pressure or any medical complications.

WARNING: A micro scale is required for accurate measurements.

Do not take this or any other supplement if you are pregnant or nursing, have high blood pressure or taking other prescription drugs.

General Statements

Always consult with your physician before taking any new dietary supplements. Expiration date on back of pouch.

USP-FCC

This is a NON-GMO ingredient produced with organic material.

Always consult with a physician before taking any new dietary supplement.

Quality Healthcare Worldwide

FDA Statement of Identity

DIETARY SUPPLEMENT

See for yourself

Pure Stevia 90% Steviosides Extract Powder by HARD RHINO label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pure Stevia 90% Steviosides Extract Powder by HARD RHINO

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size40 mg Dosage formPowder Servings per container12500 Amounts shown are per serving.

Stevia 90% Steviodies Extract Powder

Interacts with
259 drugs
40 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia 90% Steviodies Extract Powder monograph & interactions
Interaction report

Pure Stevia 90% Steviosides Extract Powder by HARD RHINO Drug Interactions

Want to check YOUR meds against Pure Stevia 90% Steviosides Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Stevia 90% Steviosides Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia 90% Steviodies Extract Powder3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Pure Stevia 90% Steviosides Extract Powder, from the product label.

HARD RHINO

Name
GUARDIAN Biosciences
City
Phoenix
State
Arizona
Pharmacist Counseling Corner

Pure Stevia 90% Steviosides Extract Powder by HARD RHINO: Common Questions

Does Pure Stevia 90% Steviosides Extract Powder by HARD RHINO interact with any medications?
Yes. Based on its ingredients, Pure Stevia 90% Steviosides Extract Powder has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Stevia 90% Steviosides Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is stevia safe to use every day?
Purified stevia at typical food amounts appears safe for regular use. However, this is a concentrated supplement dose, not a food amount, and long-term safety data are sparse. Talk with your doctor or pharmacist about whether daily use is right for you, especially if you have any medical conditions.
Can I use this if I take blood pressure or diabetes medication?
Not without checking first. Stevia may interact with both types—potentially lowering blood pressure or blood sugar further. Your doctor or pharmacist can review your specific medications and advise whether it's safe for you.
What are the most common side effects?
Bloating, dizziness, headache, muscle pain, nausea, and numbness are the most common, though they're usually mild and often fade within the first week of use.
Does stevia actually help with weight loss or blood sugar control?
We don't have enough reliable evidence yet to say how well it works for either. Some small studies suggest possible effects, but human research hasn't been conclusive enough to make a strong claim.
Is this safe during pregnancy or while breastfeeding?
The safety data on file don't include information about pregnancy or breastfeeding. Talk with your doctor or pharmacist before using it if you're pregnant, planning to become pregnant, or nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Stevia 90% Steviosides Extract Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Stevia 90% Steviosides Extract Powder label
Go deeper

The Full Monographs Behind Pure Stevia 90% Steviosides Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pure Stevia 90% Steviosides Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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