PureBi-Ome G.I. Ingredients & Drug Interactions
What is this page for?
First and foremost: checking PureBi-Ome G.I. against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
PureBi-Ome G.I. is a dietary supplement by Pure Encapsulations with 2 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 232 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Blend, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against PureBi-Ome G.I. by Pure Encapsulations
Ask about any prescription or over-the-counter medication and we check it for interactions with PureBi-Ome G.I. by Pure Encapsulations — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of PureBi-Ome G.I. by Pure Encapsulations
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
PureBi-Ome G.I. contains 5 active ingredients: two strains of Lactobacillus acidophilus (NCIMB 30157 and NCIMB 30156), Bifidobacterium bifidum (NCIMB 30153), Bifidobacterium lactis (NCIMB 30172), and L-Glutamine. These are live probiotics (beneficial bacteria) and an amino acid designed to support digestive and intestinal health.
The inactive ingredients—vegetarian capsule, potato maltodextrin, plant fiber, and silica—are excipients that hold the capsule together and aid absorption.
Does it work?
Strong evidence
L-Glutamine is rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and recovery from critical illness or trauma. The two Lactobacillus acidophilus strains are each rated Possibly Effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis, though they're rated Possibly Ineffective for atopic disease.
Bifidobacterium bifidum is rated Possibly Effective for irritable bowel syndrome and respiratory tract infections. For other potential uses listed in the data—such as allergic rhinitis, Alzheimer disease, and generalized anxiety disorder—the evidence we hold is insufficient to rate.
How safe is it?
Well-documented data
L-Glutamine is rated Likely Safe in pregnancy and is generally well tolerated by healthy adults, though people with kidney or liver disease should use it only under medical supervision. The most common side effects are gastrointestinal: belching, bloating, constipation, flatulence, diarrhea, nausea, and vomiting.
Both Lactobacillus acidophilus strains and Bifidobacterium bifidum are rated Possibly Safe in pregnancy; they're generally well tolerated in healthy adults and children, though those with weakened immune systems should be cautious. Uncommon gastrointestinal side effects include abdominal pain, dyspepsia, and burping.
A small number of trial participants reported rash or itching, though it's unclear whether the probiotics caused it. Live probiotics carry a theoretical risk of infection in severely immunocompromised patients, though this is rare.
Meds to double-check
Moderate interaction found
Before taking PureBi-Ome G.I., check with your doctor or pharmacist if you take antibiotic drugs (Moderate interaction—take them several hours apart) or anticonvulsants/seizure medications (Moderate interaction). We could not check Bifidobacterium lactis for interactions, so mention this ingredient to your pharmacist as well.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with digestive issues like irritable bowel syndrome, especially if you're not taking antibiotics. If you're on seizure medication or antibiotics, talk with your doctor or pharmacist before starting it—timing matters.
Expect possible mild bloating or digestive upset when you first begin. It's generally well tolerated, but people with weakened immunity should check with their healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about PureBi-Ome G.I., straight from the product label.
| Brand | Pure Encapsulations |
|---|---|
| Barcode (UPC) | 766298015439 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2021 |
| DSLD ID | 245992 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for PureBi-Ome G.I. by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Glutamine | 450 mg | -- |
| Lactobacillus acidophilus (NCIMB 30157) | 0 NP | -- |
| Lactobacillus acidophilus (NCIMB 30156) | 0 NP | -- |
| Bifidobacterium lactis (NCIMB 30172) | 0 NP | -- |
| Bifidobacterium bifidum (NCIMB 30153) | 0 NP | -- |
| Probiotic Blend | 0 NP | -- |
Other ingredients: Vegetarian Capsule, Potato Maltodextrin, hypoallergenic Plant Fiber, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Keep refrigerated
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.
Precautions
Warning: Probiotics may be contraindicated for immunocompromised individuals.
If you are pregnant or lactating, have any health condition or are immunocompromised, or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
General Statements
Scan to learn about our hypoallergenic supplements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Formulation
Probiotic combination to support gastrointestinal integrity and health
Gluten-free, Non-GMO & Hypoallergenic
Gluten-free, Non-GMO & Hypoallergenic
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
PureBi-Ome G.I. by Pure Encapsulations label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in PureBi-Ome G.I. by Pure Encapsulations
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Glutamine
Interacts with50 drugs
Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...
L-Glutamine monograph & interactionsProbiotic Blend
Interacts with182 drugs
Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...
Probiotic Blend monograph & interactions- › Lactobacillus acidophilus (NCIMB 30157)
- › Lactobacillus acidophilus (NCIMB 30156)
- › Bifidobacterium lactis (NCIMB 30172)
- › Bifidobacterium bifidum (NCIMB 30153)
Other (inactive) ingredients: Vegetarian Capsule, Potato Maltodextrin, Hypoallergenic Plant Fiber, Silica. These complete the product’s ingredient list but are not active constituents.
PureBi-Ome G.I. by Pure Encapsulations Drug Interactions
HelloPharmacist Interaction Report
PureBi-Ome G.I. by Pure Encapsulations interacts with antibiotics through its Lactobacillus acidophilus and Bifidobacterium bifidum content.
The most serious concern is a Moderate interaction: these live-organism probiotics can be killed by antibiotics taken at the same time, which decreases how well the probiotics work. The product also contains L-Glutamine, which carries a Moderate interaction with anticonvulsants (seizure medications) — glutamine is broken down into glutamate, an excitatory brain chemical that might work against seizure drugs, though this hasn't been reported in people yet.
Read the full breakdown — every affected drug type, severity by severity
Additionally, we could not check Bifidobacterium lactis for interactions — we hold no data for it. Altogether, these interactions span 232 individual medications.
If you take antibiotics, separate them from this product by a few hours (ask your pharmacist or doctor for the timing that works best for your situation). If you take a seizure medication, check with your doctor or pharmacist before starting this supplement.
You can also run your exact medications through the search tool on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against PureBi-Ome G.I.?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in PureBi-Ome G.I. interact with 232 drugs. Click any drug to see the details.
2 of the 2 ingredients in PureBi-Ome G.I. interact with drugs. Each result below shows which ingredient is responsible. Probiotic Blend L-Glutamine
AcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Acetazolamide interactionAmikacinAmikin, Arikayce
How Amikacin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amikacin interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Amikacin interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Aminophylline, Amobarbital, Ephedrine interactionAmobarbitalAmytal
How Amobarbital interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Amobarbital, Secobarbital interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Amoxicillin Veterinary interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin, Clavulanate Potassium interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amphotericin, Tetracycline interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Ampicillin interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Ampicillin, Sulbactam interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Ampicillin, Sulbactam interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Aprobarbital, Butabarbital, Phenobarbital interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Avibactam Sodium, Ceftazidime interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Azithromycin interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Aztreonam interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Bacampicillin interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bacitracin interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Bacitracin interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, PhenobarbitalBellophen, Susano
How Belladonna, Phenobarbital interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Belladonna, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBenznidazoleBenznidazole
How Benznidazole interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Benznidazole interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionButalbital, Phenobarbital, SecobarbitalTribarb
How Butalbital, Phenobarbital, Secobarbital interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Butalbital, Phenobarbital, Secobarbital interactionCapreomycinCapastat
How Capreomycin interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Capreomycin interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Capreomycin interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with PureBi-Ome G.I. — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Carbamazepine interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Carbenicillin Indanyl Sodium interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Cefaclor interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with PureBi-Ome G.I. — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefadroxil interactionBifidobacterium Bifidum (ncimb 30153)Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum (ncimb 30153) + Cefadroxil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in PureBi-Ome G.I. with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Probiotic Blend
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
L-Glutamine
Anticonvulsants
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.
Brand information
Manufacturer and brand details for PureBi-Ome G.I., from the product label.
Pure Encapsulations
See all Pure Encapsulations products- Name
- Pure Encapsulations
- Street Address
- 490 Boston Post Road
- City
- Sudbury
- State
- MA
- Phone Number
- 1-800-753-2277
- Web Address
- www.PureEncapsulations.com
PureBi-Ome G.I. by Pure Encapsulations: Common Questions
Does PureBi-Ome G.I. by Pure Encapsulations interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on antibiotics?
Will this help my irritable bowel syndrome (IBS)?
What's L-Glutamine doing in here?
Is it safe to take while pregnant?
What side effects should I expect?
Is this safe if I have a weak immune system?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if PureBi-Ome G.I. is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind PureBi-Ome G.I.’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Glutamine
Interacts with 50 drugsGlutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...
Read the full Glutamine monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographBifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph →Sources & How We Checked
PureBi-Ome G.I.'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 33 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glutamine 11 references
- Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
- Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
- Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
- Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
- Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
- Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
- Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
- Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
- Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
- Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
- Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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