Quantum Detox Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Quantum Detox against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Quantum Detox is a dietary supplement by Quantum Nutrition Labs with 1 active ingredient. Its ingredients are commonly taken for bone health and osteoporosis prevention, dietary calcium deficiency, heartburn relief (calcium carbonate antacids).Based on those ingredients, 168 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Calcium Bentonite Clay. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Quantum Detox by Quantum Nutrition Labs
Ask about any prescription or over-the-counter medication and we check it for interactions with Quantum Detox by Quantum Nutrition Labs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Quantum Detox by Quantum Nutrition Labs
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Calcium.
- The most serious interaction on file is rated Major.
- Some involve high-stakes drug classes: heart-rhythm medications; lithium.
- For scale: 168 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Quantum Detox, straight from the product label.
| Brand | Quantum Nutrition Labs |
|---|---|
| Barcode (UPC) | 807735128388 |
| Net contents | 90 Plant-Source Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 21, 2025 |
| DSLD ID | 329099 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Quantum Detox by Quantum Nutrition Labs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calcium Bentonite Clay | 450 mg | -- |
Other ingredients: Cellulose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Take 1 capsule, 3 times daily with 4 oz. or more of purified water. When taken with a meal, supports healthy elimination of food contaminants.
Formula
This unique smectite form of bentonite clay exhibits powerful absorptive detoxification properties. It is believed to be the only known bentonite sourced from the site of an ancient underwater volcanic eruption that was flushed with fresh water for millions of years.
Quantum Detox with unique calcium bentonite clay
OU (Kosher)
OU (Kosher) We are proud to offer many OU Kosher Certified Products.
Precautions
Keep out of reach of children.
Use only if seal is intact.
Consult your health practitioner if you are pregnant or nursing, taking medication or have a medical condition, before taking this product.
California residents only Prop 65 warning: Cancer and reproductive harm www.P65Warnings.ca.gov
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Full detoxification support
Gluten free Tested for pathogens No fillers or additives Heavy metal tested Non GMO Project Verified nongmoproject.org
Vegan friendly
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Non GMO Project Verified nongmoproject.org OU (Kosher)
General Statements
Scan to discover more
Quantum Nutrition for Quantum Health
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Quantum Detox by Quantum Nutrition Labs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Quantum Detox by Quantum Nutrition Labs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Calcium Bentonite Clay
Interacts with168 drugs
Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...
Calcium Bentonite Clay monograph & interactionsOther (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.
Quantum Detox by Quantum Nutrition Labs Drug Interactions
Quantum Detox contains a single active ingredient, and it has known interactions with 168 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Quantum Detox?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Quantum Detox interact with 168 drugs. Click any drug to see the details.
1 of the 1 ingredient in Quantum Detox interact with drugs. Each result below shows which ingredient is responsible. Calcium Bentonite Clay
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydrochlorothiazide, Propranolol interactionHydrochlorothiazide, QuinaprilAccuretic
How Hydrochlorothiazide, Quinapril interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydrochlorothiazide, Quinapril interactionHydrochlorothiazide, ReserpineHydropres, Serpasil-Esidrix, Serpasil-Esidrix #1, Serpasil-Esidrix #2
How Hydrochlorothiazide, Reserpine interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydrochlorothiazide, Reserpine interactionHydrochlorothiazide, SpironolactoneAldactazide, Aldactide 25, Aldactide 50, Spirozine
How Hydrochlorothiazide, Spironolactone interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydrochlorothiazide, Spironolactone interactionHydrochlorothiazide, TimololTimolide
How Hydrochlorothiazide, Timolol interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydrochlorothiazide, Timolol interactionHydrochlorothiazide, TriamtereneDyazide, Maxzide, Maxzide-25, Triamzide, Triazide
How Hydrochlorothiazide, Triamterene interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydrochlorothiazide, Triamterene interactionHydrochlorothiazide, ValsartanDiovan HCT
How Hydrochlorothiazide, Valsartan interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydrochlorothiazide, Valsartan interactionHydroflumethiazideSaluron
How Hydroflumethiazide interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydroflumethiazide interactionHydroflumethiazide, ReserpineSalutensin, Salutensin-Demi
How Hydroflumethiazide, Reserpine interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Hydroflumethiazide, Reserpine interactionIbandronateBoniva, Boniva IV
How Ibandronate interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayBisphosphonates Moderate
Interaction Summary
Calcium reduces the absorption of bisphosphonates.
Read the full Calcium Bentonite Clay + Ibandronate interactionIndapamideLozide, Lozol
How Indapamide interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Indapamide interactionIrbesartan, HydrochlorothiazideCoAprovel
How Irbesartan, Hydrochlorothiazide interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Irbesartan, Hydrochlorothiazide interactionLamivudine, RaltegravirDutrebis
How Lamivudine, Raltegravir interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayRaltegravir (isentress) Moderate
Interaction Summary
Calcium may reduce levels of raltegravir.
Read the full Calcium Bentonite Clay + Lamivudine, Raltegravir interactionLamivudine, Tenofovir Disoproxil FumarateTemixys
How Lamivudine, Tenofovir Disoproxil Fumarate interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate
Interaction Summary
Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Read the full Calcium Bentonite Clay + Lamivudine, Tenofovir Disoproxil Fumarate interactionLevofloxacinLeva-pak, Levaquin, Levaquin Injection
How Levofloxacin interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayQuinolone Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of quinolone antibiotics.
Read the full Calcium Bentonite Clay + Levofloxacin interactionLevofloxacin (ophthalmic)Levofloxacin
How Levofloxacin (ophthalmic) interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayQuinolone Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of quinolone antibiotics.
Read the full Calcium Bentonite Clay + Levofloxacin (ophthalmic) interactionLevothyroxineEltroxin, Estre, Euthyrox, Levo-T, Levolet, Levothroid +5 more
How Levothyroxine interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Read the full Calcium Bentonite Clay + Levothyroxine interactionLevothyroxine SodiumErmez, Thyquidity, Tirosint-Sol
How Levothyroxine Sodium interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Read the full Calcium Bentonite Clay + Levothyroxine Sodium interactionLevothyroxine, LiothyronineArmour Thyroid
How Levothyroxine, Liothyronine interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Read the full Calcium Bentonite Clay + Levothyroxine, Liothyronine interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayLithium Moderate
Interaction Summary
Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Read the full Calcium Bentonite Clay + Lithium Carbonate (prescription Drug) interactionLomefloxacinMaxaquin
How Lomefloxacin interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayQuinolone Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of quinolone antibiotics.
Read the full Calcium Bentonite Clay + Lomefloxacin interactionMethyclothiazideAquatensen, Enduron
How Methyclothiazide interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Methyclothiazide interactionMethyclothiazide, PargylineEutron
How Methyclothiazide, Pargyline interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Methyclothiazide, Pargyline interactionMethyclothiazide, ReserpineDiutensen-R
How Methyclothiazide, Reserpine interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Methyclothiazide, Reserpine interactionMetolazoneDiulo, Mykrox, Zaroxolyn
How Metolazone interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayThiazide Diuretics Moderate
Interaction Summary
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Read the full Calcium Bentonite Clay + Metolazone interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayTetracycline Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of tetracycline antibiotics.
Read the full Calcium Bentonite Clay + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayTetracycline Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of tetracycline antibiotics.
Read the full Calcium Bentonite Clay + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayTetracycline Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of tetracycline antibiotics.
Read the full Calcium Bentonite Clay + Minocycline Hydrochloride interactionMoxifloxacinAvelox
How Moxifloxacin interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayQuinolone Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of quinolone antibiotics.
Read the full Calcium Bentonite Clay + Moxifloxacin interactionNalidixic AcidNegGram
How Nalidixic Acid interacts with Quantum Detox — through 1 ingredient. Tap an ingredient for the detail:
Calcium Bentonite ClayQuinolone Antibiotics Moderate
Interaction Summary
Calcium seems to reduce the absorption of quinolone antibiotics.
Read the full Calcium Bentonite Clay + Nalidixic Acid interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Quantum Detox with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Calcium Bentonite Clay
Ceftriaxone (Rocephin)
Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.
Dolutegravir (Tivicay)
Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.
Elvitegravir (Vitekta)
Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.
Aluminum
Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.
Bisphosphonates
Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.
Calcipotriene (Dovonex)
Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.
Digoxin (Lanoxin)
Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.
Diltiazem (Cardizem, Others)
Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.
Levothyroxine (Synthroid, Others)
Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.
Lithium
Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.
Quinolone Antibiotics
Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.
Raltegravir (Isentress)
Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.
Sotalol (Betapace)
Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.
Tetracycline Antibiotics
Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.
Thiazide Diuretics
Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.
Verapamil (Calan, Others)
Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.
Calcium Channel Blockers
Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.
Brand information
Manufacturer and brand details for Quantum Detox, from the product label.
Quantum Detox by Quantum Nutrition Labs: Common Questions
Does Quantum Detox by Quantum Nutrition Labs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Quantum Detox is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Quantum Detox’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Quantum Detox's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 62 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Calcium 62 references
- Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
- Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
- Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
- Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
- Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
- Saunders D, Sillery J, Chapman R. Effect of calcium carbonate and aluminum hydroxide on human intestinal function. Dig Dis Sci 1988;33:409-13. PubMed
- Friedman PA, Bushinsky DA. Diuretic effects on calcium metabolism. Semin Nephrol 1999;19:551-6.
- Koo WK, Walters JC, Esterlitz J, et al. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82. DOI
- Raman L, Rajalakshmi K, Krishnamachari KAVR, et al. Effect of calcium supplementation to undernourished mothers during pregnancy on the bone density of the neonates. Am J Clin Nutr 1978; 31:466-9. DOI
- Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
- Chan JM, Giovannucci E, Andersson SO, et al. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer. Cancer Causes Control 1998;9:559-66.
- Butner LE, Fulco PP, Feldman G, et al. Calcium carbonate-induced hypothyroidism. Ann Intern Med 2000:132:595. PubMed
- Schneyer CR. Calcium carbonate and reduction of levothyroxine efficacy. JAMA 1998;279:750. PubMed
- Moser LR, Smythe MA, Tisdale JE. The use of calcium salts in the prevention and management of verapamil-induced hypotension. Ann Pharmacother 2000;34:622-9. PubMed
- Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA 2000;283:2822-5. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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