Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Rauwolscine Ingredients & Drug Interactions

by Gorilla Mind

Rauwolscine label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rauwolscine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Rauwolscine is a dietary supplement by Gorilla Mind with 1 active ingredient. Its ingredients are commonly taken for fat loss and weight management, bodybuilding and physique support, energy and stimulant effects.Based on those ingredients, 677 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rauwolscine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Rauwolscine by Gorilla Mind

Ask about any prescription or over-the-counter medication and we check it for interactions with Rauwolscine by Gorilla Mind — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Rauwolscine by Gorilla Mind

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: rauwolscine, a potent stimulant alkaloid. The capsule also holds inactive ingredients—gelatin, rice flour, silicon dioxide, and magnesium stearate—which are standard binders, fillers, and capsule materials.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: fat loss and athletic performance support.
  • We looked for evidence on: Athletic performance, Obesity, Weight management, Exercise performance.
  • The closest evidence on file: Rauwolscine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Rauwolscine is rated "Insufficient Reliable Evidence To Rate" for Obesity.

The evidence we hold does not establish rauwolscine as effective for athletic performance, weight loss, or sexual arousal. Our data shows insufficient reliable evidence to rate it for any of these uses.

The evidence, ingredient by ingredient Rauwolscine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rauwolscine is a potent stimulant with limited human safety data. It can affect heart rate and blood pressure, and no thorough safety evaluation has been completed.

A related chemical, yohimbine, has been associated with serious effects including seizures, loss of consciousness, paralysis, and vertigo; since rauwolscine is structurally similar, it might theoretically cause similar effects. Reported effects from yohimbine also include anxiety, impulsivity, tremor, dizziness, headache, and flushing.

The safety data advises against use during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Rauwolscine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rauwolscine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications.
  • For scale: 677 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Rauwolscine, double-check your medications with your doctor or pharmacist if you take seizure threshold lowering drugs, medications metabolized by the liver enzyme CYP2D6 (such as certain antidepressants and antiarrhythmics), blood thinners or antiplatelet drugs, calcium channel blockers (heart medications), stimulants, or clonidine. These represent Moderate severity concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Rauwolscine is a potent stimulant with limited human safety data and a wide range of documented medication interactions. If you take seizure medications, blood thinners, heart medications, other stimulants, or clonidine, you'll want to check with your doctor or pharmacist before adding this product.

Talk it over with them before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rauwolscine , straight from the product label.

Brand Gorilla Mind
Barcode (UPC) 850017020160
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 301146
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rauwolscine by Gorilla Mind, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
850017020160
IngredientAmount% DV
Rauwolscine3 mg--

Other ingredients: Gelatin, Rice Flour, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule 1-2 times per day, ideally on an empty stomach 30 minutes prior to exercise. Do not take within 6 hours of bed. To maximize efficacy, take 2-4 capsules of our stimulant-free fat loss formula "cAMP PM" with each dose of Rauwolscine.

Precautions

Warning: Keep out of reach of children. This product should not be taken by individuals who are pregnant, nursing, have or suspect a medical condition, are taking any medications, or are under 18 years of age.

This product should not be taken by individuals who are pregnant, nursing, have or suspect a medical condition, are taking any medications, or are under 18 years of age. Do not use this product with other caffeinated products, stimulants, MAO inhibitors, alcohol or other medications.

Consult a physician before taking this or any other dietary supplement.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Made In USA GMP Good Manufacturing Practice

Formula

alpha-Yohimbine

Formulation

Suppresses Appetite Increased Fat Loss Increased Energy

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rauwolscine by Gorilla Mind label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rauwolscine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rauwolscine by Gorilla Mind

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Rauwolscine

Interacts with
677 drugs
3 mg per serving Form: Rauwolfia vomitoria Root Extract

Rauwolscine (alpha-yohimbine) is a stimulant alkaloid closely related to yohimbine that is marketed mainly in fat-burning and pre-workout supplements....

Rauwolscine monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rauwolscine by Gorilla Mind Drug Interactions

Want to check YOUR meds against Rauwolscine ?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
677Drugs
677 Moderate

Ingredients driving the most interactions

Rauwolscine 677

Individual Drug Interactions

The ingredients in Rauwolscine interact with 677 drugs. Click any drug to see the details.

1 of the 1 ingredient in Rauwolscine interact with drugs. Each result below shows which ingredient is responsible. Rauwolscine

Each ingredient & the kinds of drugs it affects

For each ingredient in Rauwolscine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rauwolscine6 drug types · 677 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, rauwolscine may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Rauwolscine is structurally related to yohimbine. In vitro research shows that yohimbine inhibits platelet aggregation.

Likelihood Possible Evidence D
Calcium Channel Blockers

Theoretically, rauwolscine may have additive coronary vasodilatory effects if used with calcium channel blockers.
In vitro, rauwolscine inhibits calcium influx in aortic smooth muscle cells.

Likelihood Possible Evidence D
Clonidine (Catapres)

Theoretically, rauwolscine may inhibit the effects of clonidine.
In animal research, rauwolscine antagonized the effects of clonidine.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, rauwolscine might increase levels of drugs metabolized by CYP2D6.
Rauwolscine is structurally related to yohimbine. In vitro research shows that yohimbine inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Seizure Threshold Lowering Drugs

Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.
In animal research, intraperitoneal rauwolscine lowered the seizure threshold level of the drug metrazol.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, taking rauwolscine with stimulant drugs might increase the risk of adverse stimulant effects.
Rauwolscine has demonstrated stimulant effects in animal research.

Likelihood Possible Evidence D
Rauwolscine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Rauwolscine , from the product label.

Gorilla Mind

See all Gorilla Mind products
Name
Gorilla Mind, LLC
Street Address
7154 W State Street, STE 138
City
Boise
State
ID
ZipCode
83714
Phone Number
+1 208-757-4423
Web Address
www.gorillamind.com
Pharmacist Counseling Corner

Rauwolscine by Gorilla Mind: Common Questions

Does Rauwolscine by Gorilla Mind interact with any medications?
Yes. Based on its ingredients, Rauwolscine has a known interaction with 677 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rauwolscine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is rauwolscine, and what is it supposed to do?
Rauwolscine is a stimulant alkaloid—a potent compound that acts like a stimulant in the body. The product is marketed for athletic performance, weight loss, and sexual arousal, but our data shows insufficient reliable evidence to confirm it works for any of these uses.
Is rauwolscine safe to take?
Rauwolscine is a potent stimulant with limited human safety data and no thorough safety evaluation. It can affect heart rate and blood pressure. A related compound, yohimbine, has been linked to serious effects like seizures, loss of consciousness, and paralysis; rauwolscine might theoretically cause similar effects.
Can I take rauwolscine if I'm pregnant or breastfeeding?
The safety data advises against use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you.
Does rauwolscine interact with stimulants like caffeine or ADHD medications?
Yes. Rauwolscine has stimulant effects and theoretically may increase the risk of adverse stimulant effects if combined with stimulant drugs. Check with your doctor or pharmacist before combining it with any other stimulants.
Can rauwolscine affect my blood pressure or heart?
Yes. Rauwolscine can affect heart rate and blood pressure. It also theoretically has coronary vasodilatory effects and may interact with calcium channel blockers (heart medications). If you have heart concerns or take blood pressure medication, talk with your doctor or pharmacist first.
What ingredients are in this product besides rauwolscine?
The capsule contains gelatin, rice flour, silicon dioxide, and magnesium stearate—all standard inactive ingredients used as binders and fillers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rauwolscine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rauwolscine label
Go deeper

The Full Monographs Behind Rauwolscine ’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rauwolscine

Interacts with 677 drugs

Rauwolscine (alpha-yohimbine) is a stimulant alkaloid closely related to yohimbine that is marketed mainly in fat-burning and pre-workout supplements. Human evidence for its benefits is very...

Read the full Rauwolscine monograph →
Sources

Sources & How We Checked

Rauwolscine 's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rauwolscine 28 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Teloken C, Rhoden EL, Sogari P, et al. Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction. J Urol 1998;159:122-4. PubMed
  4. Jacobsen FM. Fluoxetine-induced sexual dysfunction and an open trial of yohimbine. J Clin Psychiatry 1992;53:119-22.
  5. Hollander E, McCarley A. Yohimbine treatment of sexual side effects induced by serotonin reuptake blockers. J Clin Psychiatry 1992;53:207-9.
  6. Sandler B, Aronson P. Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Urol 1993;41:343-5. PubMed
  7. Kearney T, Tu N, Haller C. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Ann Pharmacother 2010;44:1022-9. PubMed
  8. VandenBrink, B. M., Foti, R. S., Rock, D. A., Wienkers, L. C., and Wahlstrom, J. L. Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition. Drug Metab Dispos. 2012;40(1):47-53. PubMed
  9. Mustonen, P., Savola, J., and Lassila, R. Atipamezole, an imidazoline-type alpha(2)-adrenoceptor inhibitor, binds to human platelets and inhibits their adrenaline-induced aggregation more effectively than yohimbine. Thromb.Res 8-1-2000;99(3):231-237.
  10. Bagheri, H., Schmitt, L., Berlan, M., and Montastruc, J. L. Effect of 3 weeks treatment with yohimbine on salivary secretion in healthy volunteers and in depressed patients treated with tricyclic antidepressants. Br J Clin Pharmacol 1992;34(6):555-558. PubMed
  11. Swann, A. C., Birnbaum, D., Jagar, A. A., Dougherty, D. M., and Moeller, F. G. Acute yohimbine increases laboratory-measured impulsivity in normal subjects. Biol.Psychiatry 5-15-2005;57(10):1209-1211. PubMed
  12. Adeniyi, A. A., Brindley, G. S., Pryor, J. P., and Ralph, D. J. Yohimbine in the treatment of orgasmic dysfunction. Asian J Androl 2007;9(3):403-407. PubMed
  13. Giampreti, A., Lonati, D., Locatelli, C., Rocchi, L., and Campailla, M. T. Acute neurotoxicity after yohimbine ingestion by a body builder. Clin Toxicol.(Phila) 2009;47(8):827-829. PubMed
  14. Myers, A. and Barrueto, F., Jr. Refractory priapism associated with ingestion of yohimbe extract. J Med Toxicol. 2009;5(4):223-225.
  15. Berlin, I., Crespo-Laumonnier, B., Cournot, A., Landault, C., Aubin, F., Legrand, J. C., and Puech, A. J. The alpha 2-adrenergic receptor antagonist yohimbine inhibits epinephrine-induced platelet aggregation in healthy subjects. Clin Pharmacol.Ther. 199
  16. Swann, A. C. Mechanisms of impulsivity in bipolar disorder and related illness. Epidemiol.Psichiatr.Soc. 2010;19(2):120-130.
  17. Landis, E. and Shore, E. Yohimbine-induced bronchospasm. Chest 1989;96(6):1424. PubMed
  18. Susset, J. G., Tessier, C. D., Wincze, J., Bansal, S., Malhotra, C., and Schwacha, M. G. Effect of yohimbine hydrochloride on erectile impotence: a double-blind study. J Urol. 1989;141(6):1360-1363. PubMed
  19. Braddock, L., Cowen, P. J., Elliott, J. M., Fraser, S., and Stump, K. Binding of yohimbine and imipramine to platelets in depressive illness. Psychol.Med 1986;16(4):765-773. PubMed
  20. Charney, D. S., Heninger, G. R., and Sternberg, D. E. Assessment of alpha 2 adrenergic autoreceptor function in humans: effects of oral yohimbine. Life Sci 6-7-1982;30(23):2033-2041.
  21. Boon, N. A., Elliott, J. M., Grahame-Smith, D. G., John-Green, T., and Stump, K. A comparison of alpha 2-adrenoreceptor binding characteristics of intact human platelets identified by [3H]-yohimbine and [3H]- dihydroergocryptine. J Auton.Pharmacol 1983;3
  22. Riley AJ, Goodman R, Kellett JM, and et al. Double blind trial of yohimbine hydrochloride in the treatment of erection inadequacy. Sexual Marital Ther 1989;4(1):17-26. DOI
  23. Wylie KR. Yohimbine and sinusitis. Br J Psychiatry. 1996;169(3):384-5. PubMed
  24. Aziz TA, Hussain SA, Mahwi TO, Ahmed ZA, Rahman HS, Rasedee A. The efficacy and safety of Ginkgo biloba extract as an adjuvant in type 2 diabetes mellitus patients ineffectively managed with metformin: a double-blind, randomized, placebo-controlled trial.
  25. Godfraind T, Miller RC, Socrates Lima J. Effects of yohimbine, rauwolscine and corynanthine on contractions and calcium fluxes induced by depolarization and prostaglandin F2 alpha in rat aorta. Br J Pharmacol. 1983;80(1):115-21.
  26. Shepperson NB, Duval N, Massingham R, Langer SZ. Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog. J Pharmacol Exp Ther. 1981;219(2):540-6. DOI
  27. Szabo B, Hedler L, Starke K. Peripheral presynaptic and central effects of clonidine, yohimbine and rauwolscine on the sympathetic nervous system in rabbits. Naunyn Schmiedebergs Arch Pharmacol. 1989;340(6):648-57. PubMed
  28. Doxey JC, Lane AC, Roach AG, Virdee NK. Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. Naunyn Schmiedebergs Arch Pharmacol. 1984;325(2):136-44.

See these in context on the Rauwolscine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team