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Dietary supplement

Red Reishi Mushroom 500 mg Ingredients & Drug Interactions

by Brain Forza

Red Reishi Mushroom 500 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Red Reishi Mushroom 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Red Reishi Mushroom 500 mg is a dietary supplement by Brain Forza with 1 active ingredient. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Reishi Mushroom extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Red Reishi Mushroom 500 mg by Brain Forza

Ask about any prescription or over-the-counter medication and we check it for interactions with Red Reishi Mushroom 500 mg by Brain Forza — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Red Reishi Mushroom 500 mg by Brain Forza

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic reishi mushroom extract at 500 mg per capsule. Reishi is a fungus used in traditional medicine, and this extract is the concentrated form.

The capsule also contains vegetable cellulose and organic sorghum as inactive ingredients.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Reishi Mushroom product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Reishi Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“overall health and wellness support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for reishi's effectiveness is limited. For high cholesterol (hyperlipidemia), reishi is rated possibly ineffective based on available data.

For altitude sickness, Alzheimer disease, and athletic performance, we don't have enough reliable evidence to know whether it works. If you're considering this for one of those uses, talk with your pharmacist about what the research actually supports.

The evidence, ingredient by ingredient Reishi Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Reishi mushroom is generally well tolerated in the short term, but long-term safety hasn't been well studied, so that's something to keep in mind if you're thinking of taking it for months. Common side effects include dizziness, dry mouth, itching, nausea, rash, and stomach upset.

Respiratory allergies to reishi spores can happen, and some people report sore throat or runny nose. Rare effects include insomnia and headache.

Based on available safety data, reishi is best avoided during pregnancy and while breastfeeding. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Reishi Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Reishi Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check whether you're on blood pressure medications, blood thinners (anticoagulants) or antiplatelet drugs, or diabetes medications—all Moderate interactions with reishi mushroom. Use the medication checker on this page to look up your prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Reishi mushroom is a traditional supplement with limited proven benefits and some real medication interactions you need to watch for—especially if you're on blood pressure drugs, blood thinners, or diabetes medications. If you fall into those groups or take any prescription medication at all, check your exact drugs on this page before starting.

It's generally well tolerated short-term, but long-term safety data is sparse.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Red Reishi Mushroom 500 mg, straight from the product label.

Brand Brain Forza
Barcode (UPC) 616639120387
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 244142
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Red Reishi Mushroom 500 mg by Brain Forza, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
616639120387
IngredientAmount% DV
certified organic Reishi Mushroom extract1500 mg--

Other ingredients: Vegetable Cellulose, organic Sorghum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one capsule three times daily with water or, three capsules once daily with water.

Precautions

Manufactured in a facility that processes wheat, gluten, soy, milk, egg, shellfish, and tree nut ingredients.

Warning: Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are currently taking any prescription medications or receiving medical treatment.

Discontinue use if unusual symptoms occur.

Keep out of reach of children.

Formulation

Soy Free Gluten Free GMO Free

Vegan

Pressure cooked twice at high heat.

Reishi mushrooms are one of the staples of TCM and may support overall health and wellness.

Made in California Made in the USA Plant Grown In: USA

Certified Organic by CCOF

May promote overall health and wellness May support healthy immune function Stronger than extracts & HPLC Tested

Seals/Symbols

EarthKosher

"CCOF Certified Organic "

Formula

EarthKosher

Medicinal Mushrooms Made with Organic Full Spectrum Ganoderma Species

Our premium, lab-grown, certified organic, non-GMO, Reishi Mushroom blend. Consistent every time and naturally containing approx. 34% polysaccharides.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Tag us @BrainForza Instagram Facebook Twitter

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Red Reishi Mushroom 500 mg by Brain Forza label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Red Reishi Mushroom 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Red Reishi Mushroom 500 mg by Brain Forza

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Certified organic Reishi Mushroom extract

Interacts with
375 drugs
1500 mg per serving

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Certified organic Reishi Mushroom extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Organic Sorghum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Red Reishi Mushroom 500 mg by Brain Forza Drug Interactions

Want to check YOUR meds against Red Reishi Mushroom 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
375Drugs
375 Moderate

Ingredients driving the most interactions

certified organic Reishi Mushroom extract 375

Individual Drug Interactions

The ingredients in Red Reishi Mushroom 500 mg interact with 375 drugs. Click any drug to see the details.

1 of the 1 ingredient in Red Reishi Mushroom 500 mg interact with drugs. Each result below shows which ingredient is responsible. certified organic Reishi Mushroom extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Red Reishi Mushroom 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Reishi Mushroom extract3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
certified organic Reishi Mushroom extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Red Reishi Mushroom 500 mg, from the product label.

Brain Forza

See all Brain Forza products
Name
Brain Forza Labs Inc.
Street Address
6100 219th Street SW, Ste 480
City
Mountlake Terrace
State
WA
ZipCode
98043
Web Address
www.brainforza.com
Pharmacist Counseling Corner

Red Reishi Mushroom 500 mg by Brain Forza: Common Questions

Does Red Reishi Mushroom 500 mg by Brain Forza interact with any medications?
Yes. Based on its ingredients, Red Reishi Mushroom 500 mg has a known interaction with 375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Red Reishi Mushroom 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. There isn't enough safety data for reishi during pregnancy or breastfeeding, so it's best avoided in both cases. Talk with your doctor or pharmacist about whether it's right for you.
What are the most common side effects?
Dizziness, dry mouth, itching, nausea, rash, and stomach upset are the most frequently reported. Less commonly, people may experience insomnia or headache. If you're allergic to mold or fungal spores, you might develop respiratory allergy symptoms like sore throat or runny nose.
Does reishi actually work for high cholesterol?
No—reishi is rated possibly ineffective for lowering cholesterol based on the evidence we have. If that's your goal, talk with your pharmacist about what might actually help.
How long is it safe to take reishi?
Short-term use appears well tolerated, but long-term safety hasn't been well studied. If you're thinking of taking it for months, that's worth discussing with your pharmacist.
What does the 500 mg refer to?
That's the amount of reishi mushroom extract in each capsule—500 milligrams per dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Red Reishi Mushroom 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Red Reishi Mushroom 500 mg label
Go deeper

The Full Monographs Behind Red Reishi Mushroom 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph →
Sources

Sources & How We Checked

Red Reishi Mushroom 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
  16. Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
  17. Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.

See these in context on the Reishi Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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