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Dietary supplement

Rutin 500 mg Veg Capsules Ingredients & Drug Interactions

by BulkSupplements.com

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Rutin 500 mg Veg Capsules is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for varicose veins and chronic venous insufficiency, hemorrhoids, easy bruising and fragile capillaries.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rutin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Rutin 500 mg Veg Capsules by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: rutin, a plant compound found in foods like buckwheat and citrus. It's been studied for a range of conditions including inflammation, aging skin, and bleeding disorders.

The capsule itself is made from hypromellose (a plant-based capsule material), which is an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Rutin product and its label doesn't state a use — see Rutin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on rutin isn't established yet in the data we hold. Studies have looked at it for aging skin, autism spectrum disorder, inflammatory bowel disease, diabetes, exercise-related infections, and hemorrhoids, but the quality or amount of evidence isn't strong enough to rate any of these uses.

That doesn't mean it doesn't work — it means we need better research to know.

The evidence, ingredient by ingredient Rutin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rutin is generally well tolerated in food and when used as a short-term supplement, but long-term safety data at supplement doses are limited. A small number of people report headache, flushing, or rashes.

The safety data for supplement doses in pregnancy are limited — pregnancy is Likely Safe, but the facts don't establish strong evidence. Safety during breastfeeding is unknown, so it's best to avoid supplement doses while nursing unless your doctor advises otherwise.

Side effects, ingredient by ingredient Rutin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rutin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs — including insulin, metformin, sulfonylureas, or any other medication that lowers blood sugar — talk to your pharmacist or doctor before taking rutin. The risk is Moderate, and combining them might cause your blood sugar to drop too low.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Rutin may appeal to you if you're interested in plant-based compounds for general wellness, but the evidence for specific conditions isn't clear yet. If you take diabetes medication, talk to your pharmacist or doctor before starting — the interaction risk is real.

Anyone breastfeeding should check with their doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rutin 500 mg Veg Capsules, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003CSO4FZ
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 331299
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rutin 500 mg Veg Capsules by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg. Capsule(s)
Maximum serving Sizes:
1 Veg. Capsule(s)
Servings per container
180
UPC/BARCODE
X003CSO4FZ
IngredientAmount% DV
Rutin500 mg--

Other ingredients: Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Rutin 500 mg per serving

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 capsule once daily, or as directed by a physician.

Formulation

Free of: added sugar, soy, dairy, yeast, gluten, additives

Storage

Store in a dry, cool place

General Statements

Scan me New

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

See for yourself

Rutin 500 mg Veg Capsules by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Rutin 500 mg Veg Capsules by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veg. Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Rutin

Interacts with
86 drugs
500 mg per serving Form: Sophora japonica

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins...

Rutin monograph & interactions

Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rutin 500 mg Veg Capsules by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Rutin 500 mg Veg Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Rutin 86

Each ingredient & the kinds of drugs it affects

For each ingredient in Rutin 500 mg Veg Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rutin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking rutin with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that rutin has hypoglycemic effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Rutin 500 mg Veg Capsules, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Rutin 500 mg Veg Capsules by BulkSupplements.com: Common Questions

Does Rutin 500 mg Veg Capsules by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Rutin 500 mg Veg Capsules has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rutin 500 mg Veg Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does rutin actually do anything for my skin or energy?
The evidence isn't established yet in the data we hold. Rutin's been studied for aging skin and exercise-related infections, but we don't have enough high-quality research to say it works for either. That doesn't mean it won't help you personally — just that the science isn't clear yet.
Will rutin give me headaches?
It's possible but not common. Some people report headache, and others report flushing or rashes. Most people tolerate it well, especially for short-term use.
Is it safe to take while I'm pregnant?
Pregnancy is rated Likely Safe, but the long-term safety data at supplement doses are limited. Talk to your doctor or pharmacist for personalized advice based on your health.
Can I take it while breastfeeding?
Safety during breastfeeding is unknown, so it's best to avoid supplement doses unless your doctor advises otherwise. Check with your doctor or pharmacist before starting.
What's hypromellose, and why is it in there?
It's a plant-based material used to make the capsule itself — it's not an active ingredient. It's just the shell that holds the rutin powder.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rutin 500 mg Veg Capsules is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rutin 500 mg Veg Capsules label
Go deeper

The Full Monographs Behind Rutin 500 mg Veg Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Rutin 500 mg Veg Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rutin 2 references
  1. Mehta DK (Ex Ed). British National Formulary, Number 37. British Medical Association and Royal Pharmaceutical Society of Great Britain: London, England, March 1999.
  2. Sun C, Wang L, Sun J, Wang Z, Tang Z. Hypoglycemic and hypolipidemic effects of rutin on hyperglycemic rats. J Tradit Chin Med. 2020;40(4):640-645.

See these in context on the Rutin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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