SAMe 200 By ProThera Overview & Drug Interactions
Check For Interactions With SAMe 200
Supplement: SAMe 200 by ProThera
SAMe 200 Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
S-Adenosyl L-Methionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
-
S-Adenosyl L-Methionine Tosylate Disulfate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Drugs that interact with SAMe 200 by ProThera
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
6 Tablet(s)
|
| UPC/BARCODE | 828054010208 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| S-Adenosyl L-Methionine |
200 mg
|
SAMe |
--
|
| S-Adenosyl L-Methionine Tosylate Disulfate |
400 mg
|
SAMe |
|
| Other Ingredients: |
Cellulose
Mannitol
Sodium Starch Glycolate
Silicon Dioxide
Glyceryl Behenate
Magnesium Stearate
Enteric Coating
Forms
Titanium Dioxide
Magnesium Silicate
Triethylcitrate
Riboflavin
Glycerol Palmitostearate
Medium Chain Triglycerides
|
|---|
Label Statments:
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
|---|---|
| Brand IP Statement(s) |
- ProThera, Inc.
|
| Formula |
- 200 mg Elemental SAMe s-adenosyl l-methionine
- Each tablet contains a full 200 mg of elemental SAMe from 400 mg SAMe tosylate disulfate.
|
| FDA Statement of Identity |
- Dietary Supplement
|
| Suggested/Recommended/Usage/Directions |
- Suggested use: 1 to 6 tablets daily on an empty stomach.
|
| Precautions |
- Warning: Individuals being treated for neurological conditions, including those using prescribed medications such as antidepressants, serotonin reuptake inhibitors, and MAO inhibitors, should consult their healthcare professional before using this product. Individuals with bipolar disorder or manic depression should not take SAMe unless under medical supervision.
- Warning: Individuals being treated for neurological conditions, including those using prescribed medications such as antidepressants, serotonin reuptake inhibitors, and MAO inhibitors, should consult their healthcare professional before using this product.
- Do not use if outer seal of blister pack is broken.
- Keep out of reach of children.
|
| Formulation |
- Free of the following common allergens: milk/casein, egg, fish, shellfish, tree nuts, peanuts, wheat/gluten, and soybeans.
|
| General Statements |
- ProThera's SAMe 200 is provided in individual foil blister-packets to maximize product stability.
- Made in Italy
- ProThera provides pharmaceutical grade, stabilized SAMe manufactured under low temperature and low humidity conditions. An enteric tablet coating resistant to gastric acidity helps to further ensure a biologically active product.
- SAMe (S-Adenosylmethionine) is a derivative of the essential amino acid methionine and is formed by combining ATP with methionine.
- SAMe has a long history of clinical use with proven benefits for brain metabolism, joint function, and liver detoxification. Some of the reported beneficial actions of SAMe include:
Joint and connective tissue strength SAMe supports production of healthy connective tissue and joint structures by contributing its sulfur component for transulfuration processes that help form glucosamine and chondroitin sulfates, critical components of connective tissues.
Brain metabolism SAMe serves as a major source of methyl groups used by the brain in the synthesis of neurotransmitters such as serotonin, L-dopa, dopamine, and related hormones involved in mood regulation.
Liver function Metabolism of SAMe supports synthesis of glutathione and glutathione-dependant enzymes (glutathione peroxidase and glutathione-S-transferase), which are important antioxidants used in liver detoxification processes.
|
| Storage |
- Store in a cool, dry place (59(0)F-85(0)F) away from direct light.
|
| General |
- SAM rev100112A
|
Brand Information
See all products by this brand
| Manufactured for: | |
|---|---|
| Name | ProThera, Inc. |
| City | Reno |
| State | NV |
| ZipCode | 89521 |
| Phone Number | 888-488-2488 |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.