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Dietary supplement

Scott's Emulsion Cod Liver Oil Orange Flavour Ingredients & Drug Interactions

by GSK

Scott's Emulsion Cod Liver Oil Orange Flavour label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Scott's Emulsion Cod Liver Oil Orange Flavour against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Scott's Emulsion Cod Liver Oil Orange Flavour is a dietary supplement by GSK with 3 active ingredients. Its ingredients are commonly taken for eye and vision health, skin health and acne, immune support.Based on those ingredients, 974 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin D, Vitamin A, Ca hypophosphite. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Scott's Emulsion Cod Liver Oil Orange Flavour by GSK

Ask about any prescription or over-the-counter medication and we check it for interactions with Scott's Emulsion Cod Liver Oil Orange Flavour by GSK — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Scott's Emulsion Cod Liver Oil Orange Flavour by GSK

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Scott's Emulsion contains three active ingredients. Vitamin A supports vision, skin, and immune function.

Vitamin D helps your body absorb calcium and regulates calcium in the blood and bones. Calcium (as calcium hypophosphite) builds and maintains strong bones and teeth.

The product also contains inactive ingredients—sucrose, fructose, xanthan gum, citric acid, propylene glycol alginate, potassium sorbate, orange flavor, and Sunset Yellow FCF—that give it texture, taste, and shelf life.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: strong bones and teeth, immune health, brain development.
  • We looked for evidence on: Dental caries, Fractures, Corticosteroid-induced osteoporosis, Child development, Child growth, Fetal bone mineralization — and 3 related terms.
  • The strongest evidence on file: Vitamin D is rated "Effective" for Rickets (Natural Medicines).
  • Also on file: Vitamin D is rated "Effective" for Vitamin D deficiency.
  • Also on file: Calcium is rated "Likely Effective" for Corticosteroid-induced osteoporosis, Osteoporosis.

Vitamin A is effective for vitamin A deficiency and possibly effective for oral leukoplakia, aging skin, measles, ulcerative colitis, and bronchopulmonary dysplasia. Vitamin D is effective for familial hypophosphatemia, osteomalacia (soft bones from vitamin D lack), renal osteodystrophy, rickets, and hypoparathyroidism.

Calcium is effective for kidney failure, dyspepsia (indigestion), hypocalcemia (low blood calcium), and hyperkalemia (high potassium), and likely effective for osteoporosis.

The evidence, ingredient by ingredient Vitamin A Vitamin D Calcium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin A is generally well-tolerated at recommended doses, but high doses build up in your body and can become toxic, causing skin problems, liver damage, and in severe cases pseudotumor cerebri (dangerous brain swelling). The safety data shows vitamin A at recommended amounts is likely safe in pregnancy, though high doses—especially as retinol—can cause birth defects; at recommended amounts it's also acceptable during breastfeeding.

Vitamin D is well-tolerated and generally safe at recommended doses; very high doses over time can cause toxicity with high blood calcium. At recommended amounts, vitamin D is likely safe in pregnancy and breastfeeding, though high doses are possibly unsafe in pregnancy.

Calcium is generally safe at recommended amounts and well-tolerated when used appropriately, with most common side effects being belching, constipation, diarrhea, and stomach upset. Calcium is likely safe at recommended amounts in pregnancy and breastfeeding.

Side effects, ingredient by ingredient Vitamin A Vitamin D Calcium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Calcium, Vitamin D, Vitamin A.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium.
  • For scale: 975 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take any retinoids like isotretinoin (Accutane) or tretinoin (Retin-A); HIV integrase inhibitors dolutegravir (Tivicay) or elvitegravir (Vitekta); or the antibiotic ceftriaxone (Rocephin), especially intravenously. Also confirm if you take blood thinners like warfarin (Coumadin), tetracycline antibiotics, thiazide water pills, heart medications (verapamil, diltiazem, digoxin, sotalol), the cholesterol drug atorvastatin (Lipitor), the thyroid drug levothyroxine (Synthroid), or the integrase inhibitor raltegravir (Isentress).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is useful if you want to cover vitamin A, D, and calcium needs—particularly if you're at risk for deficiency or have a condition like rickets or osteoporosis that your doctor has identified. Because this emulsion interacts with many medications—especially HIV drugs, blood thinners, thyroid medication, and heart drugs—you need to check your exact prescriptions before starting.

Talk with your doctor or pharmacist about whether this product fits your personal health situation and current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Scott's Emulsion Cod Liver Oil Orange Flavour, straight from the product label.

Brand GSK
Market status On market
Date entered into DSLD Dec 24, 2013
DSLD ID 26874
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Scott's Emulsion Cod Liver Oil Orange Flavour by GSK, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
IngredientAmount% DV
Vitamin A850 IU--
Vitamin D85 IU--
Ca hypophosphite414 mg--

Other ingredients: Sucrose, Fructose, Xanthan Gum, Citric Acid, Propylene Glycol Alginate, Potassium Sorbate, Orange flavor, Sunset Yellow FCF

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

COD LIVER OIL

contains vitamins A & D, cod liver oil, calcium & orange juice

With Calcium

MIMS Class Vitamins A, D & E

Contents Cod liver oil.

General Statements

FOOD SUPPLEMENT NO APPROVED THERAPEUTIC CLAIM

Indications Helps develop strong bones & teeth, build up natural resistance to sickness & in healthy development of brain.

ACT Classification A11CB - Vitamin A and D in combination ; Used as dietary supplements.

Poison Schedule Non-Rx

Presentation/Packing Oral emulsion (orange flavor) 200 mL, 400 mL.

FDA Statement of Identity

VITAMIN & MINERAL SUPPLEMENT

Suggested/Recommended/Usage/Directions

Dosage Adults & childn >12 yr 15 mL tid. Childn 7-12 yr 15 mL bid, 4-6 yr 15 ml once daily, 1-3 15 mL once daily.

Storage

Storage Store below 30(0)C. Keep in a cool place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Scott's Emulsion Cod Liver Oil Orange Flavour by GSK label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Scott's Emulsion Cod Liver Oil Orange Flavour label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Scott's Emulsion Cod Liver Oil Orange Flavour by GSK

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 mL Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin A

Interacts with
387 drugs
850 IU per serving

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Vitamin D

Interacts with
715 drugs
85 IU per serving

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D monograph & interactions

Ca hypophosphite

Interacts with
168 drugs
414 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Ca hypophosphite monograph & interactions

Other (inactive) ingredients: Sucrose, Fructose, Xanthan Gum, Citric Acid, Propylene Glycol Alginate, Potassium Sorbate, Orange flavor, Sunset Yellow FCF. These complete the product’s ingredient list but are not active constituents.

Interaction report

Scott's Emulsion Cod Liver Oil Orange Flavour by GSK Drug Interactions

Want to check YOUR meds against Scott's Emulsion Cod Liver Oil Orange Flavour?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
974Drugs
16 Major 475 Moderate 483 Minor

Ingredients driving the most interactions

Vitamin D 715
Vitamin A 387
Ca hypophosphite 168

Individual Drug Interactions

The ingredients in Scott's Emulsion Cod Liver Oil Orange Flavour interact with 974 drugs. Click any drug to see the details.

3 of the 3 ingredients in Scott's Emulsion Cod Liver Oil Orange Flavour interact with drugs. Each result below shows which ingredient is responsible. Vitamin D Vitamin A Ca hypophosphite

Each ingredient & the kinds of drugs it affects

For each ingredient in Scott's Emulsion Cod Liver Oil Orange Flavour with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D8 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D full monograph & interactions

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Vitamin A full monograph & interactions

Ca hypophosphite18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Ca hypophosphite full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Scott's Emulsion Cod Liver Oil Orange Flavour, from the product label.

GSK

Name
GlaxoSmithKline
Pharmacist Counseling Corner

Scott's Emulsion Cod Liver Oil Orange Flavour by GSK: Common Questions

Does Scott's Emulsion Cod Liver Oil Orange Flavour by GSK interact with any medications?
Yes. Based on its ingredients, Scott's Emulsion Cod Liver Oil Orange Flavour has a known interaction with 974 medications, including 16 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Scott's Emulsion Cod Liver Oil Orange Flavour contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Vitamin A at recommended amounts is likely safe in pregnancy and breastfeeding, though high doses—especially as retinol—can cause birth defects in pregnancy. Vitamin D and calcium at recommended amounts are likely safe in both pregnancy and breastfeeding. Since this is a liquid emulsion, talk with your doctor or pharmacist about the right dose for you and your situation before starting.
What's the difference between the vitamin A in this product and prescription retinoids like Accutane?
Retinoids are prescription vitamin A derivatives—much more potent than the vitamin A in supplements. Taking this product with a retinoid prescription can cause dangerously high vitamin A levels and serious toxicity. Never combine them without explicit approval from your prescriber.
Can too much of this product hurt me?
Yes. Vitamin A builds up in your body and high doses can cause liver damage, skin problems, and dangerous brain swelling. Vitamin D and calcium at very high doses can also cause toxicity. Stick to the recommended dose on the label—don't take extra to feel better faster.
Will this help my bones?
Calcium is likely effective for osteoporosis, and vitamin D helps your body use calcium. If your doctor has told you that you have low bone density or osteoporosis, this product may help—but it works best alongside adequate diet, exercise, and any prescription your doctor recommends.
What are the inactive ingredients for?
The sucrose, fructose, xanthan gum, citric acid, propylene glycol alginate, potassium sorbate, orange flavor, and Sunset Yellow FCF are inactive ingredients. They give the liquid its texture, taste, sweetness, and shelf life—they're not medicinal, but they're necessary for the product to work as intended.
Does this product have any common side effects?
At recommended doses, the ingredients are generally well-tolerated. Calcium can cause belching, constipation, diarrhea, flatulence, and stomach upset in some people. If you notice any unusual symptoms, stop taking it and talk with your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Scott's Emulsion Cod Liver Oil Orange Flavour label
Go deeper

The Full Monographs Behind Scott's Emulsion Cod Liver Oil Orange Flavour’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph →
Sources

Sources & How We Checked

Scott's Emulsion Cod Liver Oil Orange Flavour's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 119 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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