Senna Leaf Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Senna Leaf Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Senna Leaf Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for short-term constipation relief, bowel cleansing before procedures, occasional irregularity.Based on those ingredients, 140 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Senna Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Senna Leaf Extract by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Senna Leaf Extract by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Senna Leaf Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains a single active ingredient: Senna Leaf Extract. There are no inactive ingredients listed.
Does it work?
Strong evidence
Senna is likely effective for constipation and possibly effective for bowel preparation — those are its established uses. The data we have doesn't establish whether it works for high potassium levels (hyperkalemia).
How safe is it?
Well-documented data
Senna is generally well tolerated when you use it short-term in the right dose. The most common side effects are belly pain and cramping, diarrhea, gas, nausea, and urgency to go.
Urine may also discolor. Skin eruptions are rare but have been reported.
The big safety point: don't use senna long-term or daily without medical advice. It's meant for short-term, occasional use — talk to your doctor before making it a routine.
Meds to double-check
Moderate interaction found
Before taking senna, double-check with your pharmacist if you take warfarin or other blood thinners (Moderate risk — diarrhea can increase bleeding), estrogens like birth control (Moderate — may reduce absorption), diuretics or water pills (Moderate — potassium loss risk), digoxin or other heart glycosides (Moderate — potassium depletion risk), or other stimulant laxatives (Moderate — compounded fluid and electrolyte loss).
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you have occasional constipation and don't take blood thinners, heart medications, diuretics, estrogens, or other laxatives, senna may help. If you're on any regular medication, especially the ones above, check with us or your doctor first.
Senna's not for daily long-term use without medical guidance.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Senna Leaf Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X000PB97NB |
| Net contents | 500 Gram(s); 17.6 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 311552 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Senna Leaf Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Senna Leaf Extract | 150 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
BulkSupplements.com Clean & Pure Bulk Supplements
Formulation
Color may vary
Free of: Added sugar, soy, dairy, yeast, gluten, additives
Natural laxative Herbal laxatives Laxative powder
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 150 mg (about 1/10 tsp) once at bedtime, or as directed by a physician.
Storage
Store in a dry, cool place
General Statements
Use an accurate milligram scale. Contents are sold by weight, not volume. Settling may occur. New
Formula
Senna laxative Senna leaves
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Senna Leaf Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Senna Leaf Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size150 mg Dosage formPowder Servings per container3333 Amounts shown are per serving.
Senna Leaf Extract
Interacts with140 drugs
Senna is a plant-based stimulant laxative that is widely used and generally effective for short-term relief of constipation. It is best used occasiona...
Senna Leaf Extract monograph & interactionsSenna Leaf Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Senna Leaf Extract by BulkSupplements.com has several documented interactions with medications.
The most serious concern is with blood thinners like warfarin (Coumadin) — senna's laxative effect can cause diarrhea, which increases how warfarin works in your body, raising your bleeding risk. One case report documented this after three weeks of heavy senna use.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check if you take estrogens (including birth control pills), diuretics (water pills), digoxin (a heart medication), or other stimulant laxatives. Estrogens may not absorb well when you're taking senna.
Diuretics and senna together can compound potassium loss in your blood (hypokalemia). Digoxin's risk of side effects goes up when senna depletes potassium.
Adding senna to another stimulant laxative risks too much fluid and electrolyte loss.
Altogether, these interactions span 140 individual medications. Before you start senna, use the medication checker below with your exact prescriptions.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Senna Leaf Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Senna Leaf Extract interact with 140 drugs. Click any drug to see the details.
1 of the 1 ingredient in Senna Leaf Extract interact with drugs. Each result below shows which ingredient is responsible. Senna Leaf Extract
Acetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Acetazolamide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Ammonium Chloride interactionArmodafinilNuvigil
How Armodafinil interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Armodafinil interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Atenolol, Chlorthalidone interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Azilsartan, Chlorthalidone interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractEstrogens Moderate
Interaction Summary
Theoretically, taking senna may interfere with the absorption of exogenous estrogens.
Read the full Senna Leaf Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Benzthiazide interactionBisacodylDulcolax, Gentlax
How Bisacodyl interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Bisacodyl interactionBisacodyl, DocusateDulcolax Laxative Tabs
How Bisacodyl, Docusate interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Bisacodyl, Docusate interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Bisoprolol, Hydrochlorothiazide interactionBumetanideBurinex
How Bumetanide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Bumetanide interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Bumetanide, Potassium interactionCaffeine, Potassium Salicylate, SalicylamideTrim-Elim
How Caffeine, Potassium Salicylate, Salicylamide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Caffeine, Potassium Salicylate, Salicylamide interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Captopril, Hydrochlorothiazide interactionCasanthranolDoxidan Liquid Gels
How Casanthranol interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Casanthranol interactionCasanthranol, DocusateDoxidan
How Casanthranol, Docusate interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Casanthranol, Docusate interactionCasanthranol, Docusate PotassiumDialose Plus
How Casanthranol, Docusate Potassium interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Casanthranol, Docusate Potassium interactionCasanthranol, Docusate SodiumPeri-Colace
How Casanthranol, Docusate Sodium interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Casanthranol, Docusate Sodium interactionCastor Oil (otc Drug)Purge
How Castor Oil (otc Drug) interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Read the full Senna Leaf Extract + Castor Oil (otc Drug) interactionChlorothiazideDiuril
How Chlorothiazide interacts with Senna Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Senna Leaf ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna Leaf Extract + Chlorothiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Senna Leaf Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Senna Leaf Extract
Digoxin (Lanoxin)
Theoretically, senna might increase the risk of adverse effects when taken with digoxin.
Overuse/abuse of senna increases the risk of adverse effects from cardiac glycosides, such as digoxin, due to potassium depletion.
Diuretic Drugs
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of senna might compound diuretic-induced potassium loss and increase the risk for hypokalemia.
Estrogens
Theoretically, taking senna may interfere with the absorption of exogenous estrogens.
Some preliminary clinical evidence suggests that senna reduces the absorption of estradiol and decreases serum concentrations of estrone and estrone sulfate by decreasing intestinal transit time.
Stimulant Laxatives
Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Senna is a stimulant laxative; concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, excessive use of senna might increase the effects of warfarin.
Senna has stimulant laxative effects and can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. In one case report, excessive use of senna for 3 weeks resulted in diarrhea, bloody stools, and an elevated INR of 11.9.
Brand information
Manufacturer and brand details for Senna Leaf Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Senna Leaf Extract by BulkSupplements.com: Common Questions
Does Senna Leaf Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is senna safe to use every day?
What are the most common side effects?
Can I take senna if I'm on birth control?
Can senna help with bowel prep for a procedure?
I take a water pill (diuretic) for my blood pressure. Can I take senna?
What's in this product besides senna?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Senna Leaf Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Senna Leaf Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Senna Leaf Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 42 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Senna 42 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Pediatrics 2001;108:776-89. PubMed
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Seybold U, Landauer N, Hillebrand S, Goebel FD. Senna-induced hepatitis in a poor metabolizer. Ann Intern Med 2004;141:650-1. PubMed
- Vanderperren B, Rizzo M, Angenot L, et al. Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides. Ann Pharmacother 2005;39:1353-7. PubMed
- Xing JH, Soffer EE. Adverse effects of laxatives. Dis Colon Rectum 2001;44:1201-9. PubMed
- Prior J, White I. Tetany and clubbing in patient who ingested large quantities of senna. Lancet 1978;2:947. PubMed
- Langmead L, Rampton DS. Review article: herbal treatment in gastrointestinal and liver disease--benefits and dangers. Aliment Pharmacol Ther 2001;15:1239-52. PubMed
- Joo JS, Ehrenpreis ED, Gonzalez L, et al. Alterations in colonic anatomy induced by chronic stimulant laxatives: the cathartic colon revisited. J Clin Gastroenterol 1998;26:283-6. PubMed
- Godding EW. Laxatives and the special role of senna. Pharmacology 1988;36:230-6. PubMed
- van Os FH. Anthraquinone derivatives in vegetable laxatives. Pharmacology 1976;14:7-17. PubMed
- Sondheimer JM, Gervaise EP. Lubricant versus laxative in the treatment of chronic functional constipation of children: a comparative study. J Pediatr Gastroenterol Nutr 1982;1:223-6. DOI
- Perkin JM. Constipation in childhood: a controlled comparison between lactulose and standardized senna. Curr Med Res Opin 1977;4:540-3. PubMed
- Shelton MG. Standardized senna in the management of constipation in the puerperium: A clinical trial. S Afr Med J 1980;57:78-80.
- [No authors listed] Senna in the puerperium. Pharmacology 1992;44:23-5. PubMed
- Passmore AP, Davies KW, Flanagan PG, et al. A comparison of Agiolax and lactulose in elderly patients with chronic constipation. Pharmacology 1993;47:249-52. PubMed
- Passmore AP, Wilson-Davies K, Stoker C, Scott ME. Chronic constipation in long stay elderly patients: a comparison of lactulose and a senna-fibre combination. BMJ 1993;307:769-71. PubMed
- MacLennan WJ, Pooler AFWM. A comparison of sodium picosulphate ("Laxoberal") with standardised senna ("Senokot") in geriatric patients. Curr Med Res Opin. 1974;2:641-7. PubMed
- Kittisupamongkol W, Nilaratanakul V, Kulwichit W. Near-fatal bleeding, senna, and the opposite of lettuce. Lancet 2008;371:784. PubMed
- Prather CM. Pregnancy-related constipation. Curr Gastroenterol Rep 2004;6:402-4. PubMed
- Werthmann WM Jr, Krees SV. Quantitative excretion of Senokot in human breast milk. Med Ann Dist Columbia 1973;42:4-5.
- Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact 1998;14:259-62. PubMed
- Faber P, Strenge-Hesse A. Senna-containing laxatives: excretion in the breast milk? Geburtshilfe Frauenheilkd 1989;49:958-62.
- Faber P, Strenge-Hesse A. Relevance of rhein excretion into breast milk. Pharmacology 1988;36 Suppl 1:212-20. PubMed
- Duncan AS. Standardized senna as a laxative in the puerperium; a clinical assessment. Br Med J 1957;1:439-41. PubMed
- Stickel, F. and Schuppan, D. Herbal medicine in the treatment of liver diseases. Dig.Liver Dis. 2007;39(4):293-304. PubMed
- BALDWIN, W. F. CLINICAL STUDY OF SENNA ADMINISTRATION TO NURSING MOTHERS: ASSESSMENT OF EFFECTS ON INFANT BOWEL HABITS. Can.Med Assoc.J 9-14-1963;89:566-568. DOI
- Sonmez, A., Yilmaz, M. I., Mas, R., Ozcan, A., Celasun, B., Dogru, T., Taslipinar, A., and Kocar, I. H. Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation. Acta Gastroenterol.Belg. 2005;68(3):385-387.
- Beuers, U., Spengler, U., and Pape, G. R. Hepatitis after chronic abuse of senna. Lancet 2-9-1991;337(8737):372-373. PubMed
- Lim, A. K., Hooke, D. H., and Kerr, P. G. Anorexia nervosa and senna misuse: nephrocalcinosis, digital clubbing and hypertrophic osteoarthropathy. Med J Aust. 1-21-2008;188(2):121-122. PubMed
- McLaughlin, A. F. Anorexia nervosa and senna misuse: nephrocalcinosis, digital clubbing and hypertrophic osteoarthropathy. Med J Aust. 9-15-2008;189(6):348. PubMed
- Soyuncu, S., Cete, Y., and Nokay, A. E. Portal vein thrombosis related to Cassia angustifolia. Clin.Toxicol.(Phila) 2008;46(8):774-777.
- Levine, D., Goode, A. W., and Wingate, D. L. Purgative abuse associated with reversible cachexia, hypogammaglobulinaemia, and finger clubbing. Lancet 4-25-1981;1(8226):919-920. PubMed
- Malmquist, J., Ericsson, B., Hulten-Nosslin, M. B., Jeppsson, J. O., and Ljungberg, O. Finger clubbing and aspartylglucosamine excretion in a laxative-abusing patient. Postgrad.Med J 1980;56(662):862-864. PubMed
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