Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

#Shatter SX-7 Watermelon Fusion Ingredients & Drug Interactions

by MuscleTech

#Shatter SX-7 Watermelon Fusion label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking #Shatter SX-7 Watermelon Fusion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

#Shatter SX-7 Watermelon Fusion is a dietary supplement by MuscleTech with 3 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 1,077 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against #Shatter SX-7 Watermelon Fusion by MuscleTech

Ask about any prescription or over-the-counter medication and we check it for interactions with #Shatter SX-7 Watermelon Fusion by MuscleTech — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of #Shatter SX-7 Watermelon Fusion by MuscleTech

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • “Sodium” is listed as a grouped ingredient — the label gives one combined amount (30 mg) without saying how much of each component you get.

Shatter SX-7 contains nine ingredients, including five actives with defined roles. Beta-alanine (CarnoSyn) supports athletic performance and muscle work.

Caffeine Anhydrous boosts mental alertness and athletic performance. Holy Basil extract, Nutmeg extract (Myristica fragrans), and Grains of Paradise extract are traditional botanical ingredients added for their purported ergogenic and wellness properties.

The product also includes three proprietary blends: Ultimate Muscle Building & Pump Complex and Extreme Energy & Focus Complex (whose exact ingredients and amounts we don't disclose on file), plus Brown Algae extract. Sodium is listed as a blend component.

The remaining ingredients are inactive — natural and artificial flavors, citric acid, sweeteners (acesulfame potassium and sucralose), salt, calcium silicate, and the color FD&C Red No. 40.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: powerful pre-workout with clinically tested ingredients.
  • We looked for evidence on: Athletic performance, Physical performance, Exercise-induced muscle breakdown, Exercise-induced muscle soreness, Mental alertness, Muscle strength — and 2 related terms.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Caffeine is rated "Likely Effective" for Mental alertness.
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.

Beta-alanine (CarnoSyn) is rated Possibly Effective for athletic performance and physical performance — it may help with muscle work and endurance, though evidence isn't conclusive. The evidence for its other listed uses — age-related cognitive decline, COPD, general cognitive function, and menopausal symptoms — is insufficient to establish whether it helps.

Caffeine is rated Likely Effective for mental alertness and athletic performance, meaning good evidence supports its use for focus and sports performance. Holy Basil, Nutmeg, Brown Algae, and the proprietary blends don't have effectiveness ratings in our data — the evidence for them isn't established, or we hold no data.

Grains of Paradise extract has no effectiveness ratings on file either.

The evidence, ingredient by ingredient Sodium Beta-alanine Caffeine Holy Basil Adenosine Nutmeg Grains Of Paradise

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-alanine is generally well tolerated in healthy adults but commonly causes a harmless tingling sensation (paresthesia), usually starting on the scalp within 20 minutes and lasting about an hour. Avoid it during pregnancy and breastfeeding — there isn't enough safety information.

Caffeine is generally safe in moderate amounts for healthy adults, though high doses carry serious risk. Limit intake during pregnancy and discuss safe limits with your doctor; small amounts pass into breast milk and moderate intake is usually acceptable but can affect the baby.

Holy Basil is generally well tolerated short-term in adults, with occasional loose stools or nausea reported, but avoid it during pregnancy and breastfeeding due to animal safety concerns. Adenosine supplement safety is limited and not well studied; avoid it during pregnancy and breastfeeding.

Nutmeg is safe as a food spice but becomes toxic at larger doses — avoid medicinal amounts and concentrated supplements. Grains of Paradise is likely safe in food amounts, but supplement safety isn't well studied; avoid medicinal doses during pregnancy and breastfeeding.

We hold no pregnancy or breastfeeding safety data for Brown Algae extract, Ultimate Muscle Building & Pump Complex, or Extreme Energy & Focus Complex.

Side effects, ingredient by ingredient Sodium Beta-alanine Caffeine Holy Basil Adenosine Nutmeg Grains Of Paradise

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 6 matched ingredients can interact with medications — Nutmeg, Caffeine, Adenosine, Holy Basil.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 954 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take Dipyridamole or any stimulant like Ephedrine (Major severity), or pentobarbital, phenobarbital, carbamazepine (Tegretol), clozapine, cimetidine, quinolone antibiotics, blood thinners, diabetes medications, sedatives, anticholinergic drugs, or certain psychiatric medications (Moderate severity). The product contains caffeine and adenosine plus botanical extracts that interact with many drug classes — your pharmacist can confirm whether your specific medications are affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a pre-workout powder designed for athletic performance, built mainly around beta-alanine and caffeine — ingredients with decent evidence for those goals. If you take heart medications (especially Dipyridamole or carbamazepine), blood thinners, diabetes drugs, sedatives, antipsychotics, or seizure medications, you must check your exact prescriptions with the tool on this page before using it.

Talk to your pharmacist or doctor, especially if you're pregnant, breastfeeding, or have caffeine sensitivity.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about #Shatter SX-7 Watermelon Fusion, straight from the product label.

Brand MuscleTech
Barcode (UPC) 631656706130
Net contents 6.12 oz.; 174 Gram(s)
Market status On market
Date entered into DSLD Aug 25, 2015
DSLD ID 48167
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for #Shatter SX-7 Watermelon Fusion by MuscleTech, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
12 Gram(s)
Maximum serving Sizes:
12 Gram(s)
Servings per container
30
UPC/BARCODE
631656706130
IngredientAmount% DV
Calories15 {Calories}--
Total Carbohydrates3 Gram(s)1%
Sodium30 mg1%
CarnoSyn1200 mg--
Caffeine Anhydrous160 mg--
Holy Basil extract20 mg--
Adenosine 5'-Triphosphate Disodium200 mg--
Myristica fragrans extract100 mg--
Brown Algae extract36 mg--
Ultimate Muscle Building & Pump Complex1400 mg--
Extreme Energy & Focus Complex336 mg--
Grains of Paradise extract20 mg--

Other ingredients: Natural and Artificial flavors, Citric Acid, Acesulfame Potassium, Salt, Calcium Silicate, Sucralose, FD&C Red No. 40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The most powerful pre-workout experience with clinically tested ingredients!

It is unlike anything you’ve ever tried! The unique, clean formula was designed to help you shatter your personal records and workout plateaus.

Shatter personal records & plateaus!

The most powerful pre-workout experience with clinically tested ingredients 147% Increase in muscle strength Subjects gained 8.8 LBS. of lean muscle in 12 weeks

Relentless energy, power & muscle pumps for more explosive workouts

Natural and artificial flavors

Results based on core ingredient testing. See back for study details.

30 servings

#Shatter(TM) SX-7(TM) is manufactured according to cGMP standards, as is required for all dietary supplements.

Made in the U.S.A. from international ingredients.

New super extreme pre-workout

Formulation

New #Shatter(TM) SX-7(TM) is a creatine-free pre-workout formulated with super-extreme and cutting-edge, premium ingredients to deliver a powerful and unparalleled workout experience.

Brand IP Statement(s)

#Shatter(TM) SX-7(TM) truly does work!

Protected by patent #6,723,737, 7,671,038, 7,629,329, 5,965,596, 6,426,361, 7,504,376 and 8,067,381

PEAK ATP(R) is a registered trademark of TSI USA Inc. and is used under license. Uses of ATP are licensed to Iovate by TSI USA Inc. under U.S. Patent Numbers 6,723,737, 7,671,038 and 7,629,329.

CarnoSyn(R) is licensed under one or more of U.S. patent numbers 5,965,596, 6,426,361, 7,504,376 and 8,067,381, each of which is owned by Natural Alternatives International, Inc. (NAI). NAI is also the owner of the registered trademark CarnoSyn(R).

(C) 2014. Patent pending.

Formula

1. Peak ATP(R) (Adenosine 5’- triphosphate disodium) – Hard-training subjects who supplemented with Peak ATP(R) in a 12-week human clinical study at the University of Tampa increased strength by 147% more than subjects using a placebo. Even better, these same subjects gained 8.8 lbs. of lean muscle versus the placebo group, who only gained 4.6 lbs. – that’s 90% more lean muscle. The Peak ATP(R) compound also forces crazy muscle pumps unlike anything you’ve ever felt. 2. Myristica fragrans – A nutmeg seed that contains a premium compound called myristicin, which contributes to the unique sensory experience. 3. Ecklonia cava – A premium brown algae that contains unique polyphenols called phlorotannins. 4. Holy basil (as Ocimum tenuiflorum) – An adaptogenic herb that contains ociglycoside I, rosmarinic acid, and triterpene acids such as oleanoic and ursolic acid. 5. Beta-alanine – #Shatter(TM) SX-7(TM) contains a 1,200mg dose of beta-alanine to help boost your muscle carnosine levels. 6. Grains of paradise – Contains the pungent compound 6-paradol. 7. Caffeine – #Shatter(TM) SX-7(TM) provides a potent dose of the stimulant caffeine for increased focus, endurance, and energizing effects.

Only pre-workout with Peak ATP(R) & Myristica for an unparalleled sensory experience.

One serving of this product contains up to as much caffeine as 2 cups of coffee.

Seals/Symbols

Research & development

Made in the USA from international ingredients

PEAK ATP(R)

CarnoSyn(TM) Carnosine Synthesizer

Precautions

Processed in a facility that also processes egg, milk, peanut, shellfish, soy and wheat ingredients.

Do not use if packaging has been tampered with.

Stimulant sensitive individuals should assess their tolerance before using. Do not exceed 2 scoops in a 24-hour period. Drink 10 glasses of water daily for general good health. Read the entire label before use and follow directions provided.

WARNING: Not intended for use by persons under 18.

Do not use if pregnant or nursing.

Discontinue use and consult a medical doctor if you experience unusual symptoms.

Consult a medical doctor before use if you have been treated for, or diagnosed with, or have a family history of any medical condition, or if you are using any prescription or over-the-counter drug(s), including blood thinners.

One serving of this product contains up to as much caffeine as 2 cups of coffee. Caffeine sensitive individuals may experience the following symptoms, including (but not limited to) restlessness, nervousness, tremors, headache, anxiety, palpitations, increased heart rate, or difficulty sleeping. Consult a medical doctor before starting any diet or exercise program. Do not exceed recommended serving. Improper use of this product will not improve results and is not advised. Use only as directed.

KEEP OUT OF REACH OF CHILDREN.

Storage

Store in a cool, dry place (60(0)F to 80(0)F).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

DIRECTIONS: Take 2 servings (2 scoops) with 8 to 12 oz. of water and consume 30 to 45 minutes before your workout.

General

9754US 0414

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

#Shatter SX-7 Watermelon Fusion by MuscleTech label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

#Shatter SX-7 Watermelon Fusion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in #Shatter SX-7 Watermelon Fusion by MuscleTech

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size12 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
30 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Ultimate Muscle Building & Pump Complex

1400 mg per serving

Extreme Energy & Focus Complex

336 mg per serving

Other (inactive) ingredients: Natural and Artificial flavors, Citric Acid, Acesulfame Potassium, Salt, Calcium Silicate, Sucralose, FD&C Red No. 40. These complete the product’s ingredient list but are not active constituents.

Interaction report

#Shatter SX-7 Watermelon Fusion by MuscleTech Drug Interactions

Want to check YOUR meds against #Shatter SX-7 Watermelon Fusion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,077Drugs
10 Major 1,006 Moderate 61 Minor

Ingredients driving the most interactions

Sodium 205

Individual Drug Interactions

The ingredients in #Shatter SX-7 Watermelon Fusion interact with 1,077 drugs. Click any drug to see the details.

1 of the 3 ingredients in #Shatter SX-7 Watermelon Fusion interact with drugs. Each result below shows which ingredient is responsible. Sodium

Each ingredient & the kinds of drugs it affects

For each ingredient in #Shatter SX-7 Watermelon Fusion with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for #Shatter SX-7 Watermelon Fusion, from the product label.

MuscleTech

See all MuscleTech products
Name
Iovate Health Sciences U.S.A. Inc.
Street Address
1105 North Market Street, Suite 1330
City
Wilmington
State
DE
ZipCode
19801
Pharmacist Counseling Corner

#Shatter SX-7 Watermelon Fusion by MuscleTech: Common Questions

Does #Shatter SX-7 Watermelon Fusion by MuscleTech interact with any medications?
Yes. Based on its ingredients, #Shatter SX-7 Watermelon Fusion has a known interaction with 1,077 medications, including 10 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
#Shatter SX-7 Watermelon Fusion contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this cause that pins-and-needles tingling I've heard about?
Yes, possibly. Beta-alanine commonly causes paresthesia — a harmless tingling that usually starts on your scalp within 20 minutes and lasts about an hour. The intensity depends on the dose; you may not feel it at lower amounts, but it's a normal side effect, not dangerous.
Can I take this if I'm pregnant or breastfeeding?
Not safely, based on the data we have. Beta-alanine and Holy Basil lack adequate pregnancy safety information, so they're best avoided. Caffeine is classified as Possibly Safe in pregnancy but should be limited — ask your doctor about safe amounts. Small amounts of caffeine pass into breast milk; moderate intake is usually considered acceptable but can affect the baby.
Does beta-alanine actually help with athletic performance?
Beta-alanine is rated Possibly Effective for athletic and physical performance, which means there's some evidence it may help, but it's not conclusive. Caffeine in this product is rated Likely Effective for mental alertness and athletic performance, so it has stronger support for focus and endurance.
What's Adenosine 5'-Triphosphate in this product for?
Adenosine (ATP) is included as part of the pre-workout formula for muscle and energy support, though it's more commonly studied in prescription cardiac contexts. The supplement evidence for oral ATP is limited, and it can interact with several heart and anticonvulsant medications.
Are there any inactive ingredients I should know about?
The inactive ingredients are natural and artificial flavors, citric acid, acesulfame potassium and sucralose (sweeteners), salt, calcium silicate, and FD&C Red No. 40 (color). If you're sensitive to artificial sweeteners or dyes, check these before you buy.
What does the 'Ultimate Muscle Building & Pump Complex' in this product contain?
We don't have the detailed ingredient breakdown for that proprietary blend on file. Ask the manufacturer directly, or check the full product label, to see what's in it — that will help your pharmacist check for interactions too.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if #Shatter SX-7 Watermelon Fusion is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

#Shatter SX-7 Watermelon Fusion label
Go deeper

The Full Monographs Behind #Shatter SX-7 Watermelon Fusion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Caffeine

Interacts with 655 drugs

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredness for most healthy adults, but too muc...

Read the full Caffeine monograph → Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph → Herb & supplement monograph

Adenosine

Interacts with 47 drugs

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat certain fast heart rhythms. As an over-t...

Read the full Adenosine monograph → Herb & supplement monograph

Nutmeg

Interacts with 528 drugs

Nutmeg is a popular cooking spice that has long been used in traditional medicine for digestion and other complaints, but there is little solid human research to support its medicinal use. I...

Read the full Nutmeg monograph → Herb & supplement monograph

Grains Of Paradise

Grains of paradise is a West African spice in the ginger family that people use for digestion, as a spice, and more recently in supplements aimed at metabolism. Early human research suggests...

Read the full Grains Of Paradise monograph →
Sources

Sources & How We Checked

#Shatter SX-7 Watermelon Fusion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 336 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
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Grains Of Paradise 2 references
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See these in context on the Grains Of Paradise monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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