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Dietary supplement

Shepherd's Purse Non-Alcohol Ingredients & Drug Interactions

by Hawaii Pharm

Shepherd's Purse Non-Alcohol label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Shepherd's Purse Non-Alcohol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Shepherd's Purse Non-Alcohol is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for heavy or prolonged menstrual bleeding, minor bleeding (nosebleeds, wounds), mild diuretic.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Shepherd's Purse extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Shepherd's Purse Non-Alcohol by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Shepherd's Purse Non-Alcohol by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Shepherd's Purse Non-Alcohol by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: certified organic Shepherd's Purse extract. Shepherd's purse is a plant traditionally used for menstrual and postpartum support, though the clinical evidence for these uses is not yet reliable enough to rate.

The liquid is delivered in a base of vegetable palm glycerin and artesian Hawaiian water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Shepherd's Purse's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support healthy menstrual function.
  • We looked for evidence on: Menorrhagia, menstrual bleeding, heavy periods.
  • The closest evidence on file: Shepherd's Purse is rated "Insufficient Reliable Evidence To Rate" for Menorrhagia (Natural Medicines).

The data we hold doesn't establish reliable evidence for shepherd's purse in either postpartum complications or menorrhagia (heavy menstrual bleeding). Both uses are rated as having insufficient reliable evidence to rate, which means we can't tell you whether it works for these purposes based on current research.

The evidence, ingredient by ingredient Shepherd's Purse

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Shepherd's purse seems to be well tolerated when used orally in small amounts for a short time. However, human safety data are limited.

The supplement should be avoided during pregnancy because it may stimulate the uterus. It should also be avoided while breastfeeding due to insufficient safety information.

Adverse effects traditionally associated with it include sedation, high or low blood pressure, abnormal thyroid function, irregular menstruation, and heart palpitations, though these are not commonly reported with typical short-term use.

Side effects, ingredient by ingredient Shepherd's Purse

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Shepherd's Purse.
  • The most serious interaction on file is rated Moderate.
  • For scale: 264 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any sedating drugs (sleep aids, anxiety medications, opioids) and thyroid hormone replacement therapy with your pharmacist. These are the medication types we have documented interactions for with shepherd's purse.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Shepherd's Purse Non-Alcohol may be considered by adults for short-term use, but the evidence for its intended purposes isn't established. If you take sedating medications or thyroid hormone, check with your pharmacist before starting.

Avoid it entirely if you're pregnant or breastfeeding. Talk with your pharmacist about whether this product fits your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Shepherd's Purse Non-Alcohol, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 0748399924827
Net contents 4 Fluid Ounce(s); 120 mL
Market status Off market
Date entered into DSLD Dec 26, 2020
DSLD ID 238609
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Shepherd's Purse Non-Alcohol by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
0748399924827
IngredientAmount% DV
certified organic Shepherd's Purse extract0 NP--

Other ingredients: Vegetable Palm Glycerin, crystal clear artesian Hawaiian Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Non-Alcohol Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.

Super concentrated liquid herbal extract Dry herb/menstruum ratio: 1:3

Contains no alcohol

Description: We produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic. We use a cold maceration extraction method, so that the active constituents of the herbs are extracted and maintained.

Manufactured in an FDA registered facility. Ultra Sonic

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.

Precautions

Warnings: Keep out of the reach of children.

Not to be used during pregnancy. Consult a physician before using if nursing or taking any medications.

Do not use if you are allergic to any ingredients.

Do not use if seal is broken or missing.

Storage

Refrigerate after opening.

Formula

(Capsella bursa-pastoris)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Shepherd's Purse Non-Alcohol by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Shepherd's Purse Non-Alcohol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Shepherd's Purse Non-Alcohol by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Certified organic Shepherd's Purse extract

Interacts with
264 drugs
0 NP per serving

Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is ver...

Certified organic Shepherd's Purse extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Crystal clear artesian Hawaiian Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Shepherd's Purse Non-Alcohol by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Shepherd's Purse Non-Alcohol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
264Drugs
264 Moderate

Ingredients driving the most interactions

certified organic Shepherd's Purse extract 264

Individual Drug Interactions

The ingredients in Shepherd's Purse Non-Alcohol interact with 264 drugs. Click any drug to see the details.

1 of the 1 ingredient in Shepherd's Purse Non-Alcohol interact with drugs. Each result below shows which ingredient is responsible. certified organic Shepherd's Purse extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Shepherd's Purse Non-Alcohol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Shepherd's Purse extract2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, concomitant use may interfere with thyroid dysfunction therapy.

Likelihood Possible Evidence D
certified organic Shepherd's Purse extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Shepherd's Purse Non-Alcohol, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Pharmacist Counseling Corner

Shepherd's Purse Non-Alcohol by Hawaii Pharm: Common Questions

Does Shepherd's Purse Non-Alcohol by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Shepherd's Purse Non-Alcohol has a known interaction with 264 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Shepherd's Purse Non-Alcohol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
No. Shepherd's purse may stimulate the uterus, and the safety data advises against use during pregnancy. Talk with your doctor about alternatives.
Is it safe to breastfeed while taking this?
Not enough safety information exists for breastfeeding. The data advises against it. Check with your pharmacist or doctor for personalized advice.
Does shepherd's purse actually help with heavy periods?
The clinical evidence isn't solid enough to say. Heavy menstrual bleeding is listed as having insufficient reliable evidence to rate, so we can't confirm it works for that purpose.
What's in the liquid besides the extract?
The liquid base is vegetable palm glycerin and crystal clear artesian Hawaiian water — no alcohol.
What side effects should I watch for?
When used short-term in small amounts, it's generally well tolerated. Adverse effects traditionally linked to shepherd's purse include sedation, high or low blood pressure, heart palpitations, and irregular menstruation, though these aren't common with typical use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Shepherd's Purse Non-Alcohol is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Shepherd's Purse Non-Alcohol label
Go deeper

The Full Monographs Behind Shepherd's Purse Non-Alcohol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Shepherd's Purse

Interacts with 264 drugs

Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is very limited. Because it may affect blood c...

Read the full Shepherd's Purse monograph →
Sources

Sources & How We Checked

Shepherd's Purse Non-Alcohol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Shepherd's Purse 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Naafe M, Kariman N, Keshavarz Z, et al. Effect of hydroalcoholic extracts of Capsella bursa-pastoris on heavy menstrual bleeding: A randomized clinical trial. J Altern Complement Med. 2018;24(7):694-700. PubMed
  4. Ghalandari S, Kariman N, Sheikhan Z, et al. Effect of hydroalcoholic extract of Capsella bursa pastoris on early postpartum hemorrhage: A clinical trial study. J Altern Complement Med. 2017;23(10):794-799.

See these in context on the Shepherd's Purse monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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