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Dietary supplement

Shu Di Huang Sugar Free Ingredients & Drug Interactions

by Herbal Terra

Shu Di Huang Sugar Free label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Shu Di Huang Sugar Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Shu Di Huang Sugar Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for kidney and adrenal support, anemia and blood building (traditional), inflammatory conditions.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rehmannia glutinosa Root Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Shu Di Huang Sugar Free by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Shu Di Huang Sugar Free by Herbal Terra — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Shu Di Huang Sugar Free by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Rehmannia glutinosa Root Extract, Dry. Rehmannia is a root used in traditional herbal medicine, particularly in East Asian practice, often valued for its potential effects on the blood and kidneys.

The liquid also includes inactive ingredients — alcohol, water, and glycerin — which serve as a base and preservative for the extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Rehmannia's overall clinical evidence instead.

Moderate

Some clinical evidence supports Rehmannia for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Chronic kidney disease (CKD) — rated "Possibly Effective" (Natural Medicines).

The evidence we hold shows that Rehmannia is possibly effective for chronic kidney disease (CKD). For other uses — aplastic anemia, atopic disease, osteoporosis, diabetes, and diabetic nephropathy — the evidence is currently insufficient to rate.

That means either we don't have enough human trials, or the ones we do have aren't strong enough to call it effective yet.

The evidence, ingredient by ingredient Rehmannia

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for Rehmannia are limited, and product quality varies, so approach with caution. The safety data advise against use during pregnancy and while breastfeeding because there isn't enough information to know whether it's safe in these times.

No adverse side effects were reported in the data we hold, but the overall safety profile is not well established in humans.

Side effects, ingredient by ingredient Rehmannia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rehmannia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check if you're on any blood pressure medications or diabetes medications with your pharmacist. Both are rated Moderate severity interactions with Rehmannia.

No other drug interactions are documented for this ingredient.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you have chronic kidney disease and want to explore herbal options, this might be worth discussing with your doctor or pharmacist. But if you take blood pressure or diabetes medication, or if you're pregnant or breastfeeding, skip this one unless your prescriber says otherwise.

Talk to your pharmacist before starting — the interaction potential and limited safety data mean this needs a careful personal review.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Shu Di Huang Sugar Free, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7238360619386
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 325400
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Shu Di Huang Sugar Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7238360619386
IngredientAmount% DV
Rehmannia glutinosa Root Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Rehmannia glutinosa

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic raw material.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Shu Di Huang Sugar Free by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Shu Di Huang Sugar Free label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Shu Di Huang Sugar Free by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Rehmannia glutinosa Root Extract, Dry

Interacts with
258 drugs
983 mg per serving

Rehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human eviden...

Rehmannia glutinosa Root Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Shu Di Huang Sugar Free by Herbal Terra Drug Interactions

Want to check YOUR meds against Shu Di Huang Sugar Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Rehmannia glutinosa Root Extract, Dry 258

Individual Drug Interactions

The ingredients in Shu Di Huang Sugar Free interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in Shu Di Huang Sugar Free interact with drugs. Each result below shows which ingredient is responsible. Rehmannia glutinosa Root Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Shu Di Huang Sugar Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rehmannia glutinosa Root Extract, Dry2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).

Likelihood Possible Evidence D
Rehmannia glutinosa Root Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Shu Di Huang Sugar Free, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Shu Di Huang Sugar Free by Herbal Terra: Common Questions

Does Shu Di Huang Sugar Free by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Shu Di Huang Sugar Free has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Shu Di Huang Sugar Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Rehmannia safe during pregnancy or breastfeeding?
The safety data advise against use during pregnancy and while breastfeeding. There isn't enough information to know either way, so talk with your doctor or pharmacist for personalized advice.
What is Rehmannia supposed to do?
In traditional herbal medicine, Rehmannia is valued for its effects on blood and kidney health. Our data show it's possibly effective for chronic kidney disease, but evidence for other uses — like diabetes, osteoporosis, and anemia — is insufficient.
Why can't I take this with blood pressure or diabetes medication?
Animal research shows Rehmannia may lower blood pressure and blood sugar on its own. Combined with medication that does the same thing, you risk dangerously low blood pressure or low blood sugar.
Are there any side effects I should know about?
No adverse effects were reported in our data, but human safety information overall is limited and varies by product quality. If you experience any unusual symptoms, stop and talk to your pharmacist.
What are the inactive ingredients?
The liquid base includes alcohol, water, and glycerin. If you need to avoid any of these — like if you're sensitive to alcohol — check with your pharmacist before use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Shu Di Huang Sugar Free is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Shu Di Huang Sugar Free label
Go deeper

The Full Monographs Behind Shu Di Huang Sugar Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rehmannia

Interacts with 258 drugs

Rehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...

Read the full Rehmannia monograph →
Sources

Sources & How We Checked

Shu Di Huang Sugar Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rehmannia 3 references
  1. Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
  2. Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
  3. Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.

See these in context on the Rehmannia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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