Strong Bones Power Shake Ingredients & Drug Interactions
by Herb Stop
What is this page for?
First and foremost: checking Strong Bones Power Shake against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Strong Bones Power Shake is a dietary supplement by Herb Stop with 8 active ingredients. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 1,377 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Chamomile, Valerian, Alfalfa. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Strong Bones Power Shake by Herb Stop
Ask about any prescription or over-the-counter medication and we check it for interactions with Strong Bones Power Shake by Herb Stop — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Strong Bones Power Shake by Herb Stop
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Strong Bones Power Shake contains 8 ingredients. The active ones are spirulina (a blue-green algae), valerian (an herb traditionally used for sleep), alfalfa (a legume leaf), watercress, horsetail, chamomile, baobab (a fruit), and coconut water.
There are no inactive fillers or other ingredients listed.
Does it work?
Not established
The evidence for this product's individual ingredients is mixed and mostly limited. Spirulina is possibly effective for high blood pressure, but evidence for acne, hay fever, anemia, and arsenic poisoning is insufficient.
Valerian is possibly effective for insomnia but lacks reliable evidence for restless legs, pre-procedural anxiety, stress, and period pain. For alfalfa, watercress, horsetail, baobab, and coconut water, the data we hold shows insufficient evidence to rate their usefulness for any condition listed.
No effectiveness data exists for chamomile in our records.
How safe is it?
Well-documented data
Spirulina is generally well tolerated, though the most common side effects are abdominal cramps, bloating, diarrhea, dizziness, fatigue, flatulence, headache, nausea, and vomiting. Rare but serious allergic reactions including anaphylaxis have been reported.
A key concern: quality varies widely and some products are contaminated with toxins or heavy metals — the safety data advises caution. Valerian is generally well tolerated short-term, with common effects being drowsiness, dizziness, mental slowness, headache, and vivid dreams.
Long-term safety is not well studied. If you stop valerian after extended use, taper slowly to avoid withdrawal symptoms like anxiety and insomnia; rare cases of hepatotoxicity have been reported.
Alfalfa is generally well tolerated in small food amounts but carries estrogen-like activity — supplement doses are best avoided in pregnancy. Watercress in food amounts is safe; raw wild watercress can carry parasitic flukes.
Horsetail may be used short-term but crude forms contain thiaminase, which can cause thiamine deficiency with prolonged use. Baobab can trigger IgE-mediated anaphylaxis in sensitive individuals.
Coconut is generally safe in food amounts but can cause allergic reactions ranging from hives to anaphylaxis. There is not enough safety data on chamomile in our records.
Meds to double-check
Major interaction found
Before taking this product, double-check these medication types: blood thinners like warfarin (Major severity from alfalfa), then sleep aids and anti-anxiety drugs (Moderate from valerian), diabetes medications (Moderate from spirulina, alfalfa, horsetail, and Minor from coconut water), immune-suppressing drugs (Moderate from spirulina and alfalfa), diuretics and lithium (Moderate from watercress and horsetail), muscle relaxants like chlorzoxazone (Moderate from watercress), and antiretroviral HIV drugs including efavirenz (Moderate from horsetail). Alcohol also adds to valerian's sedative effects (Moderate).
No interactions are documented for chamomile in our data.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
This is a multi-ingredient supplement with several moderate interactions — especially with blood thinners, sleep medications, diabetes drugs, and immune-suppressing drugs. The product's effectiveness for bone health (or any specific condition) is not established in our data.
If you take any prescription medication, particularly warfarin, CNS depressants, diabetes medications, lithium, or immune-suppressing drugs, check your exact medications with the tool on this page before starting, and talk to your pharmacist or doctor first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 8 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Strong Bones Power Shake, straight from the product label.
| Brand | Herb Stop |
|---|---|
| Net contents | 4 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2023 |
| DSLD ID | 297439 |
| Product type | Botanical With Nutrients |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Strong Bones Power Shake by Herb Stop, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0 NP | -- |
| Spirulina | 0 NP | -- |
| Valerian | 0 NP | -- |
| Alfalfa | 0 NP | -- |
| Watercress | 0 NP | -- |
| Horsetail | 0 NP | -- |
| Chamomile | 0 NP | -- |
| Baobab | 0 NP | -- |
| Coconut Water | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
79% organic content
Vegan.
No preservatives. No artificial flavoring.
100% natural. No animal testing.
Made in USA.
Formula
This power shake contains herbs that are high in essential nutrients - specifically calcium & magnesium.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
1/2 tsp/cup Step 1 measure Step 2 blend Step 3 enjoy! Suggested use: Mix 1/2 teaspoon in 8 oz of liquid (water, your morning shake, juice, etc.). Blend well and drink. Be creative - add to your cereals, oatmeals, yogurt, etc.
Precautions
Safety guideline: Consult your physician prior to use if you are currently taking anti-coagulant therapy.
Not to be used during pregnancy or lactation. If you have a medical condition or take pharmaceutical drugs, please consult with your doctor before use.
Keep away from children.
Use only as directed on label.
Seals/Symbols
Cruelty free
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Strong Bones Power Shake by Herb Stop label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Strong Bones Power Shake by Herb Stop
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 Teaspoon(s) Dosage formPowder Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Spirulina
- › Valerian
- › Alfalfa
- › Watercress
- › Horsetail
- › Chamomile
- › Baobab
- › Coconut Water
Strong Bones Power Shake by Herb Stop Drug Interactions
HelloPharmacist Interaction Report
Strong Bones Power Shake by Herb Stop contains several ingredients with documented interactions.
The most serious concern is alfalfa, which may reduce the anticoagulant effects of warfarin (a blood thinner used to prevent clots) because alfalfa is high in vitamin K, which directly opposes warfarin's action — this is a Major severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions span several drug categories. Spirulina may increase bleeding risk with blood thinners and antiplatelet drugs, interfere with drugs that suppress the immune system, and raise the risk of low blood sugar (hypoglycemia) if you take diabetes medications.
Valerian — used for sleep — can add to the sedating effects of CNS depressants (sleep aids, anxiety medications, pain relievers), alcohol, and alprazolam, and may weakly increase levels of certain drugs your liver breaks down. Alfalfa also theoretically interferes with birth control pills, hormone therapy, immune-suppressing drugs, and diabetes medications.
Watercress may increase lithium levels and reduce warfarin's effectiveness, and can increase side effects of chlorzoxazone (a muscle relaxant). Horsetail carries moderate risks with diabetes drugs, diuretics (water pills), lithium, and HIV medications like efavirenz.
Coconut water has a Minor interaction with diabetes drugs, raising hypoglycemia risk slightly. We could not check chamomile for interactions — no data is on file for it.
Baobab showed no interactions in our data.
Altogether, these interactions span 1,337 individual medications. Check your exact medications with the tool below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Strong Bones Power Shake?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Strong Bones Power Shake interact with 1,377 drugs. Click any drug to see the details.
7 of the 8 ingredients in Strong Bones Power Shake interact with drugs. Each result below shows which ingredient is responsible. Chamomile Valerian Alfalfa Spirulina Horsetail Coconut Water Watercress
WarfarinWarfarin
How Warfarin interacts with Strong Bones Power Shake — through 5 ingredients. Tap an ingredient for the detail:
AlfalfaWarfarin (coumadin) Major
Interaction Summary
Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Read the full Alfalfa + Warfarin interactionSpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina + Warfarin interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Warfarin interactionWatercressWarfarin (coumadin) Moderate
ValerianCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Strong Bones Power Shake — through 5 ingredients. Tap an ingredient for the detail:
AlfalfaWarfarin (coumadin) Major
Interaction Summary
Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Read the full Alfalfa + Warfarin Sodium interactionChamomileWarfarin (coumadin), Cytochrome P450 2c9 (cyp2c9) Substrates +2 Moderate
Interaction Summary
German chamomile might increase the effects of warfarin and increase the risk of bleeding.
Read the full Chamomile + Warfarin Sodium interactionSpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina + Warfarin Sodium interactionWatercressWarfarin (coumadin) Moderate
Interaction Summary
Watercress contains vitamin K.
Read the full Watercress + Warfarin Sodium interactionValerianCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Warfarin Sodium interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina + 6-mercaptopurine interactionAlfalfaImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Ado-trastuzumab Emtansine interactionValerianCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Strong Bones Power Shake — through 1 ingredient. Tap an ingredient for the detail:
HorsetailNucleoside Reverse Transcriptase Inhibitors (nrtis) Moderate
Interaction Summary
Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
Read the full Horsetail + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Strong Bones Power Shake — through 1 ingredient. Tap an ingredient for the detail:
HorsetailNucleoside Reverse Transcriptase Inhibitors (nrtis) Moderate
Interaction Summary
Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
Read the full Horsetail + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Strong Bones Power Shake — through 1 ingredient. Tap an ingredient for the detail:
SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abemaciclib interactionValerianCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abiraterone interactionValerianCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abiraterone Acetate interactionValerianCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Strong Bones Power Shake — through 3 ingredients. Tap an ingredient for the detail:
AlfalfaImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa + Abrocitinib interactionSpirulinaAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina + Abrocitinib interactionChamomileCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acalabrutinib interactionValerianCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Strong Bones Power Shake — through 4 ingredients. Tap an ingredient for the detail:
SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Spirulina + Acarbose interactionAlfalfaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Alfalfa + Acarbose interactionHorsetailAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking horsetail with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Horsetail + Acarbose interactionCoconut WaterAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Strong Bones Power Shake — through 1 ingredient. Tap an ingredient for the detail:
SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Strong Bones Power Shake — through 3 ingredients. Tap an ingredient for the detail:
ChamomileCns Depressants Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full Chamomile + Acepromazine interactionValerianCns Depressants Moderate
Interaction Summary
Valerian can have additive sedative effects when used concomitantly with CNS depressant drugs.
Read the full Valerian + Acepromazine interactionAlfalfaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ValerianGlucuronidated Drugs Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Strong Bones Power Shake — through 3 ingredients. Tap an ingredient for the detail:
ValerianGlucuronidated Drugs Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Aspirin interactionSpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina + Acetaminophen, Aspirin interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Strong Bones Power Shake — through 3 ingredients. Tap an ingredient for the detail:
ValerianGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Aspirin, Caffeine interactionSpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina + Acetaminophen, Aspirin, Caffeine interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Strong Bones Power Shake — through 3 ingredients. Tap an ingredient for the detail:
AlfalfaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionValerianGlucuronidated Drugs Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ValerianGlucuronidated Drugs Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Butalbital interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital, Caffeine interactionValerianGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ValerianCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +2 Moderate
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Acetaminophen, Butalbital, Caffeine, Codeine interactionChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital, Codeine interactionValerianGlucuronidated Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ValerianCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Valerian can have additive sedative effects when used concomitantly with CNS depressant drugs.
Read the full Valerian + Acetaminophen, Butalbital, Codeine Phosphate interactionChamomileCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Strong Bones Power Shake — through 3 ingredients. Tap an ingredient for the detail:
ChamomileCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full Chamomile + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionValerianGlucuronidated Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAlfalfaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ValerianCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Valerian can have additive sedative effects when used concomitantly with CNS depressant drugs.
Read the full Valerian + Acetaminophen, Caffeine, Codeine interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Codeine, Salicylamide interactionValerianGlucuronidated Drugs, Cns Depressants +2 Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full Chamomile + Acetaminophen, Caffeine, Dihydrocodeine interactionValerianGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Strong Bones Power Shake — through 2 ingredients. Tap an ingredient for the detail:
ValerianCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Read the full Valerian + Acetaminophen, Caffeine, Isometheptene interactionChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Strong Bones Power Shake — through 3 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Pyrilamine interactionValerianGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
Read the full Valerian + Acetaminophen, Caffeine, Pyrilamine interactionHorsetailDiuretic Drugs Moderate
Interaction Summary
Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Read the full Horsetail + Acetaminophen, Caffeine, Pyrilamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Strong Bones Power Shake with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Chamomile
Cns Depressants
Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.
Contraceptive Drugs
Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.
Estrogens
Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.
Tamoxifen (Nolvadex)
Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.
Warfarin (Coumadin)
German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.
Valerian
Alcohol (Ethanol)
Valerian can have additive sedative effects when used concomitantly with alcohol.
Valerian has sedative effects. Theoretically, valerian might have an additive sedative effect when combined with alcohol. Excessive sedation has been reported in an alcohol-abusing individual who took valerian and Gingko biloba. However, the potential interaction between valerian and alcohol has been disputed in other research. Limited evidence suggests that a combination of valerian 160 mg and lemon balm 80 mg (Euvegal) does not cause further deterioration in reaction ability and reaction rate when taken with alcohol as compared to the effects of alcohol alone.
Alprazolam (Xanax)
Valerian can have additive sedative effects when used with alprazolam. Also, valerian in high doses might modestly increase alprazolam levels, though this is not likely to be clinically significant.
Valerian has sedative effects. Theoretically, valerian might cause additive sedation when combined with alprazolam. Also, a small pharmacokinetic study shows that taking valerian extract 1000 mg daily (providing 11 mg valerenic acid) might increase alprazolam levels by about 19%. This might be due to valerian's mild inhibition of cytochrome P450 3A4 (CYP3A4). Despite being statistically significant, this increase is not likely to be clinically significant.
Cns Depressants
Valerian can have additive sedative effects when used concomitantly with CNS depressant drugs.
Theoretically, concomitant use of valerian and drugs with sedative and anesthetic properties may cause additive therapeutic and adverse effects.
Glucuronidated Drugs
Valerian might weakly inhibit glucuronidation and increase concentrations of drugs metabolized by UGT1A1 and UGT2B7.
In vitro research shows that methanolic valerian extract and valerenic acid might competitively inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1) and UGT2B7.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP2D6.
Although some in vitro evidence suggests that valerian affects CYP2D6, clinical pharmacokinetic (PK) studies show that valerian is unlikely to affect the CYP2D6 enzyme. In one PK study, taking valerian 1000 mg (providing about 11 mg valerenic acid) nightly for 14 days did not affect the metabolism of dextromethorphan, a CYP2D6 substrate. In another PK study, taking valerian 125 mg three times daily for 28 days did not affect metabolism of debrisoquine, an accepted CYP2D6 probe-substrate.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP3A4.
Although some in vitro evidence suggests that valerian extract might inhibit or induce CYP3A4, clinical pharmacokinetic (PK) studies show that valerian does not have a clinically significant effect on the CYP3A4 enzyme. In one PK study, taking valerian 125 mg three times daily for 28 days did not affect metabolism of midazolam, an accepted CYP3A4 probe-substrate. In another PK study, taking valerian 1000 mg (providing about 11 mg valerenic acid) nightly for 14 days modestly increases levels of alprazolam, a CYP3A4 substrate, suggesting mild inhibition of CYP3A4. However, this mild inhibition is unlikely to be clinically relevant.
Alfalfa
Warfarin (Coumadin)
Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Alfalfa contains a large amount of vitamin K. This could theoretically interfere with the activity of warfarin.
Antidiabetes Drugs
Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that alfalfa decreases blood sugar in diabetic mice. Also, in one case report, a diabetic patient experienced hypoglycemia after consuming alfalfa extract. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Contraceptive Drugs
Theoretically, alfalfa might interfere with the activity of contraceptive drugs.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.
Estrogens
Theoretically, alfalfa might interfere with hormone therapy.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.
Immunosuppressants
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
In vitro research and human case reports suggest that alfalfa may have immunostimulant effects.
Photosensitizing Drugs
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Animal research suggests that excessive doses of alfalfa may increase photosensitivity, possibly due to its chlorophyll content. It is unclear if this effect would be clinically relevant in humans.
Spirulina
Anticoagulant/Antiplatelet Drugs
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.
Antidiabetes Drugs
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.
Immunosuppressants
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.
Horsetail
Antidiabetes Drugs
Theoretically, taking horsetail with antidiabetes drugs might increase the risk of hypoglycemia.
Equisetum myriochaetum has demonstrated hypoglycemic activity in clinical research. In an animal diabetic model, Equisetum giganteum had hypoglycemic effects. It is unclear whether other horsetail species have hypoglycemic effects.
Diuretic Drugs
Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Laboratory research shows that various species of horsetail have diuretic properties. Due to its diuretic effects, there has been concern that taking horsetail along with potassium-depleting diuretics might increase the risk for hypokalemia. However, pharmacokinetic research in humans shows that taking horsetail 900 mg daily for 4 days does not affect urinary excretion of electrolytes, including potassium and sodium, despite having a diuretic effect similar to taking hydrochlorothiazide 25 mg daily. It is unclear if taking horsetail for a longer duration would affect electrolyte levels. Until more is known, use with caution.
Efavirenz (Sustiva)
Theoretically, horsetail might decrease the levels and clinical effects of efavirenz.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral regimen that included efavirenz. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing horsetail, the viral loads became undetectable in both cases. The exact mechanism of this interaction is unknown. It is also unclear if this interaction is specific to efavirenz or if it is related to various components of antiretroviral therapy.
Lithium
Theoretically, horsetail might increase the levels and adverse effects of lithium.
Animal research suggests that horsetail has diuretic properties. Theoretically, due to these potential diuretic effects, horsetail might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Nucleoside Reverse Transcriptase Inhibitors (Nrtis)
Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral therapy. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing the supplement, the viral loads became undetectable in both cases. The exact mechanism of these interactions is unknown. It is also unclear if these interactions are specific to NRTIs or if they are related to various components of antiretroviral therapy.
Coconut Water
Antidiabetes Drugs
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.
Watercress
Chlorzoxazone (Parafon Forte, Paraflex)
Watercress might reduce the metabolism of chlorzoxazone and increase its effects and side effects. Clinical research in healthy volunteers shows that a single ingestion of watercress 50 grams increases the chlorzoxazone plasma concentration-time curve by about 56% and increases its half-life by about 53%.
Lithium
Watercress is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, watercress might reduce excretion and increase levels of lithium.
Warfarin (Coumadin)
Watercress contains vitamin K. Consuming large amounts of watercress might antagonize the anticoagulant effects of warfarin.
Brand information
Manufacturer and brand details for Strong Bones Power Shake, from the product label.
Herb Stop
See all Herb Stop products- Name
- Herb Stop
- Phone Number
- 1.877.345.4372
- Web Address
- HerbStopOnline.com
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Strong Bones Power Shake’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Blue-green Algae
Interacts with 327 drugsBlue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and general wellness. Evidence for most heal...
Read the full Blue-green Algae monograph → Herb & supplement monographValerian
Interacts with 902 drugsValerian is an herb whose root is widely used as a natural sleep aid and for calming nerves. The evidence is mixed and often weak, so it may help some people sleep but does not work reliably...
Read the full Valerian monograph → Herb & supplement monographAlfalfa
Interacts with 583 drugsAlfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of these uses is limited. It is best avoid...
Read the full Alfalfa monograph → Herb & supplement monographWatercress
Interacts with 6 drugsWatercress is a nutrient-rich leafy green that provides vitamins A, C, and K plus minerals and antioxidant plant compounds. Eaten as a food it is generally safe and healthy for most people,...
Read the full Watercress monograph → Herb & supplement monographHorsetail
Interacts with 188 drugsHorsetail is a traditional herb most often used as a mild diuretic and for hair, nail, and bone support, but high-quality human evidence is limited. It can cause thiamine (vitamin B1) loss w...
Read the full Horsetail monograph → Herb & supplement monographGerman Chamomile
Interacts with 960 drugsGerman chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible benefits for mild anxiety and some skin o...
Read the full German Chamomile monograph → Herb & supplement monographBaobab
Baobab is a nutrient-rich fruit from a tree native to Africa and is most often used as a food and source of vitamin C and fiber. Early research hints it may help with blood sugar and digesti...
Read the full Baobab monograph → Herb & supplement monographCoconut
Interacts with 86 drugsCoconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...
Read the full Coconut monograph →Sources & How We Checked
Strong Bones Power Shake's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 165 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Blue-green Algae 22 references
- Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
- Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
- Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
- Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
- Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
- Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
- Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
- Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
- Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
- Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
- Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
- Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
- Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
- Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
- Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
- Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
- Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
- Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
- Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
- Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
- Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
- Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed
Valerian 37 references
- Willey LB, Mady SP, Cobaugh DJ, Wax PM. Valerian overdose: a case report. Vet Hum Toxicol 1995;37:364-5.
- Kuhlmann J, Berger W, Podzuweit H, Schmidt U. The influence of valerian treatment on "reaction time, alertness and concentration" in volunteers. Pharmacopsychiatry 1999;32:235-41. PubMed
- Klepser TB, Klepser ME. Unsafe and potentially safe herbal therapies. Am J Health Syst Pharm 1999;56:125-38. PubMed
- Houghton PJ. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol 1999;51:505-12. PubMed
- Garges HP, Varia I, Doraiswamy PM. Cardiac complications and delirium associated with Valerian root withdrawal. [Letter to the Editor]. JAMA 1998;280:1566-7. PubMed
- Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
- MacGregor FB, Abernethy VE, Dahabra S, et al. Hepatotoxicity of herbal remedies. BMJ 1989;299:1156-7. PubMed
- Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med 1985;2:144-8. PubMed
- Hadley S, Petry JJ. Valerian. Am Fam Physician 2003;67:1755-8..
- Glass JR, Sproule BA, Herrmann N, et al. Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects. J Clin Psychopharmacol 2003;23:260-8. PubMed
- Lefebvre T, Foster BC, Drouin CE, et al. In vitro activity of commercial valerian root extracts against human cytochrome P450 3A4. J Pharm Pharmaceut Sci 2004;7:265-73.
- Yuan CS, Mehendale S, Xiao Y, et al. The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesth Analg 2004;98:353-8. PubMed
- Donovan JL, DeVane CL, Chavin KD, et al. Multiple night-time doses of valerian (Valeriana officinalis) had minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteers. Drug Metab Dispos 2004;32:1333-6. PubMed
- Gurley BJ, Gardner SF, Hubbard MA, et al. In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes. Clin Pharmacol Ther 2005;77:415-26. PubMed
- Gutierrez S, Ang-Lee MK, Walker DJ, Zacny JP. Assessing subjective and psychomotor effects of the herbal medication valerian in healthy volunteers. Pharmacol Biochem Behav 2004;78:57-64. PubMed
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